House vacation rentals in Lake City

4.88 out of 5 average rating, 147 reviews

Home in O'Brien

The Hidden Palms

Relax in this peaceful, spacious, family friendly farmhouse with a quaint tropical vibe in the backyard. We are minutes from several springs as well as the Suwannee, Ichetucknee & Santa Fe rivers. Only 6 miles from the Spring Diving Capital of the World & the nearest town for gas/food/etc. Our home features amenities that will make this a perfect spot for your family to host a memorable vacation for adults & children. Enjoy our indoor-outdoor living space, firepit, fully stocked home & farm.

4.95 out of 5 average rating, 149 reviews

Riverfront Retreat (Ichetucknee) w/ Kayaks & Tubes

DIRECTLY ON the crystal clear waters of the Ichetucknee River, the Riverfront Retreat is a beautiful rustic home and the perfect place to find peace, rest & relaxation. Swim or go tubing on what US Travel News deemed as Florida's best tubing river. Private viewing platform with floating dock right on the water. 4 Bedrooms & sleeps 9 with ping pong & foosball and is perfect for almost any group. We offer tubes & kayaks for guests to use during their stay. After 5 guests, $25 per person, per day.

The lodge features a two-level design with a spacious upstairs screened porch illuminated by warm lights. A staircase connects to the lower level, where additional seating is visible, surrounded by lush greenery, creating a comfortable outdoor space.

4.99 out of 5 average rating, 179 reviews

The Suwannee River Rest & Adventures

Nestled in Branford, FL, along the scenic Suwannee River in Hatch Bend, this pet friendly, three-bedroom, three-bath lodge is perfect for weekends or extended stays. Upstairs features two king bedrooms with ensuite baths, a cozy living area with a gas fireplace, and a fully equipped modern kitchen. Downstairs offers a king bedroom, full bath, kitchenette, and living space. An enclosed elevator makes transporting gear easy. Experience comfort, charm, and Suwannee River beauty at our retreat!

4.96 out of 5 average rating, 209 reviews

A spacious kitchen showcases modern white cabinetry and a large island with seating for four. Stylish pendant lights hang above the island, and stainless steel appliances are integrated into the design. A cozy living area is visible in the background, providing a seamless flow to the space.

Home in Jennings

Gated 5 acres with fitness, 5 tvs, king bed

There's plenty of boat and trailer parking on gated property. 3 types of coffee makers. Keurig ( with pods), French press, Drip. Quiet, secluded, New custom home on 5+ acres. 6-7 min off I75 Kick back and relax in this calm, stylish space. Peaceful Country Living meets Luxury and Style. Nearby Fun: 1. Jennings GP- Motor Track 2. Spirit of the Suwanee 3. Madison State Blue Park -Madison River 4 Wild Adventures - 30 Min 6. Cross Roads Metroplex 7. The Florida HikingTrail and much more...

A well-lit wooden boardwalk extends toward the lake, flanked by trees. The scene is set during twilight, with a soft glow illuminating the path. The reflection of the evening sky and trees on the calm water enhances the tranquil ambiance of the location.

4.96 out of 5 average rating, 394 reviews

Papa Joe’s Lake House

Quiet little piece of heaven on earth. Enjoy the lake, sit by a fire, enjoy the nature God has provided in our sanctuary on Pickett Lake. Boat ramp is 100 yards down the road. 4 kayaks, canoe, and paddleboard are provided, all of which can be launched from the house. Fish from the dock or explore the lake. Use the grill or take a short drive to Branford or Mayo and enjoy some of the restaurants. Come boat, fish, or swim in the lake or just enjoy the lake view. Outdoor fire pit includes wood.

A round treehouse structure is nestled among lush greenery. The building is elevated on stilts, featuring a spacious porch with white railings. A paved path leads to the entrance, surrounded by trees and foliage that create a natural, serene setting.

4.96 out of 5 average rating, 238 reviews

Otter Landing on Santa Fe River, 13 private acres

Spend all the time you want at home in Nature relaxing or recreating. This unique treehouse home is set high up in the trees and on 13 acres of natural habitat on the banks of the Santa Fe River. The Santa Fe has so much wildlife, and we are near the famous crystalline Ichetucknee River and miles of public trails. We share our kayaks, a canoe, and many amenities for your stay. So go for a solo paddle, join local guide trips to various springs, or hike on the property and at nearby parks.

A comfortable living area features a light-colored sofa positioned adjacent to an accent chair. A wooden entertainment center holds a television, while a patterned area rug anchors the space. Natural light is provided by a nearby window, enhancing the inviting atmosphere.

4.84 out of 5 average rating, 130 reviews

Deerwood Cottage 3BR /2BA Brick Home

Peaceful 3 BR 2 BA This is your adventure headquarters! Bring the whole family, or just get away to this great place with lots of space! This house is located on an acre in a nice rural neighborhood within 1.5 miles of a great park with hiking trails, biking trails, great fishing, birdwatching, disc golf and beautiful wildlife! Within a short drive are unique to North Florida features which include the following: crystal clear springs; a national forest ; racing venues; breweries & more

A picnic area is visible with a wooden table and grill, set against a backdrop of trees casting dappled shadows. The simple structure of the nearby building is framed by the natural landscape, enhancing the outdoor space.

4.88 out of 5 average rating, 189 reviews

O'LE LADYBUG COTTAGE

***Newly added Wifi*** 5 minutes from I-75 exit # 414 .10 minutes to Ichetucknee Springs State park, 10 minutes to O'leno State park,25 minutes to Gainesville,15 minutes to High Springs,15 minutes to Lake City.Biking,hiking,diving,fishing,canoeing,kayaking and more all close by.Full kitchen,laundry room,bbq area with park grill and picnic table,fire pit,located on the backside of 500 acres of woods,lots of wildlife to view.Bring your cooler and bikes and enjoy the tranquility and nature.

Sunlight streams through the trees of a tranquil forest, creating a warm glow amidst the natural setting. Leafy branches arch overhead, while the ground is covered in a carpet of leaves, inviting moments of peaceful reflection and connection with nature.

4.91 out of 5 average rating, 138 reviews

Waldhaus! Forest sanctuary close to springs!

House nestled in the middle of the forest. Peaceful retreat with 2 decks. Fire pit and grill with gazebo. You are 5 min to I 75 , 5 min to Oleno park and 10 min to itchetucknee river. Ginnie springs is 25 min. Earth link internet w Roku . Around the property you see at any given day deer turkey & cows. Star gazing . The house is very cozy , well equipped , roomy. Baby travel bed/pen and table seat . Corn hole game. Great fun for family !

4.95 out of 5 average rating, 402 reviews

The single-story home is surrounded by lush green grass and trees, featuring two sets of windows flanked by dark green shutters. A small porch with a seating area sits in front, complemented by flowering bushes. The sky is bright with scattered clouds.

Home in Mayo

Small Town Charm & Living

Water Lover’s Paradise! Great place to get away for spring hopping, kayaking, canoeing, cave diving, or just a little R & R. If crystal clear springs are what you’re looking for, we’re just minutes from Lafayette Blue Springs State Park, Troy Springs State Park, Wes Skiles Peacock Springs State Park, & the Ichetucknee Springs State Park. We’re just 35 minutes from the Gulf of Mexico and fresh seafood restaurants.

A single-story home is depicted with a welcoming front porch, surrounded by lush greenery and tall pine trees. A rainbow arcs gently across the sky, adding a colorful backdrop to the residence. The driveway provides easy access to the entrance.

4.88 out of 5 average rating, 214 reviews

Fenced yard, pet friendly. Near I-75 and I-10.

2 bedroom house, that can sleep 4. Living room, kitchen, a full bath, and laundry room are available to guests. We are pet friendly. Fully fenced in backyard with a doggie door. 1 mile from I 75 and 12 miles south of I-10. Close to Ichetucknee Springs, Stephen Foster, and Big Shoals State Parks. Gainesville is 40 minutes south.

4.83 out of 5 average rating, 102 reviews

Home in High Springs

Sweetwater on the Range | Cozy Cabin • Firepit

↞----- Newly-Renovated ~ Family-Friendly Farm Getaway -----↠ ▻ Near world-famous freshwater Springs (Ginnie Springs, Blue, Ichetucknee) ▻ Sun-drenched Sunroom, ideal for gatherings or game nights ▻ Backyard Fire Pit, igniting cozy evenings Under the Stars ▻ Cozy all-wood cabin-style Rural Retreat to rest and recharge

Popular amenities for Lake City house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

Superhost

An aerial view captures a well-maintained tennis court featuring orange and blue courts set within a green area. Surrounding the courts, a spacious yard includes a multi-level house and various outdoor installations. The natural scenery of trees and greenery enhances the outdoor space.

4.8 out of 5 average rating, 100 reviews

La Casona

A stylish living room is illuminated by natural light through large windows. A plush sectional sofa and a comfortable armchair are arranged around a low coffee table, featuring a decorative centerpiece. A contemporary chandelier hangs overhead, providing additional ambient light.

4.97 out of 5 average rating, 120 reviews

Rare & Spacious Family Oasis • Private Pool &Games

Superhost

A two-story white house features a classic design with black shutters and a covered front entrance. The wide pathway leads to the main door, surrounded by neatly landscaped greenery. Large windows allow natural light to flow into the home, enhancing its welcoming appearance.

4.88 out of 5 average rating, 128 reviews

Coaches House - 1.5 mile from Ben Griffin Stadium

4.89 out of 5 average rating, 28 reviews

Jungle Oasis at Rose Creek- Pool & Nature Getaway

4.93 out of 5 average rating, 45 reviews

A spacious house is set in a green landscape, framed by tall trees and a fenced yard. The structure features a traditional design with a gabled roof, large front windows, and a welcoming porch area. A grassy lawn enhances the serene outdoor space.

Home in Live Oak

Spacious Private Pool Home

4.82 out of 5 average rating, 252 reviews

A serene outdoor space features a wooden deck with four Adirondack chairs arranged around a central fire pit. Soft lighting is provided by hanging string lights, enhancing the ambiance. Surrounding trees provide shade and a sense of privacy in the green, grassy area.

Home in Alachua

Gated Golf Getaway close to Springs and UF

An outdoor space features a wooden gazebo with a hot tub underneath, illuminated by string lights. The area is surrounded by trees, and fallen leaves are scattered on the ground, enhancing the relaxed ambiance of the setting.

4.95 out of 5 average rating, 141 reviews

Orange Blossom Retreat | Pool, Hot Tub, and Game's

4.88 out of 5 average rating, 76 reviews

A spacious outdoor area features a large rectangular pool and a smaller adjacent hot tub. Surrounding the pool, a paved patio offers ample space for seating and relaxation. Lush greenery and open fields are visible in the background under a clear blue sky.

Home in Alachua

House in High Springs with Pool - Close to town

Weekly house rentals

5 out of 5 average rating, 26 reviews

Modern, comfortable 2 BR, 1 bath, full kitchen.

4.97 out of 5 average rating, 29 reviews

Home in White Springs

Luxury Riverside Escape on the Suwannee

5 out of 5 average rating, 68 reviews

A comfortable living area features a mix of seating options, including a dark brown sofa and woven armchairs. A decorative area rug complements the space, while sunlight filters through window treatments. Artwork is displayed on the wall, and a small table holds a lamp.

Home in White Springs

Hillside Abode in Historic White Springs

4.87 out of 5 average rating, 166 reviews

A serene scene of a cypress log home surrounded by lush greenery is reflected in the calm waters of the Santa Fe River. A wooden dock is visible at the water's edge, inviting relaxation amid nature.

Home in High Springs

Family Treehouse on The Santa Fe River

4.93 out of 5 average rating, 225 reviews

A charming cottage is nestled among lush green trees, showcasing light yellow exterior walls. The landscape is dappled with sunlight filtering through the leaves, creating a serene atmosphere. Large windows allow natural light to illuminate the interior, enhancing the connection with the surrounding nature.

Home in Alachua

Peaceful Cottage in Alachua Florida

5 out of 5 average rating, 66 reviews

A serene patio area is covered with slate stone tiles, featuring a round table surrounded by chairs. Lush greenery and decorative planters are placed around the space. The entrance to the home is visible to the right, complementing the peaceful natural setting.

Home in Fort White

Private relaxing stay in Fort White

4.83 out of 5 average rating, 24 reviews

Allen & Evelyn Country Comfort

4.96 out of 5 average rating, 57 reviews

~ La Casita ~ about 6 minutes to I-75

Private house rentals

A spacious bedroom features a plush bed with a white comforter, accentuated by decorative pillows. Two bedside tables with matching lamps stand beside the bed. A large piece of wall art depicting blue waves hangs above the headboard, while natural light enters through a nearby window.

4.86 out of 5 average rating, 91 reviews

Lake City Luxury New listing whole house

5 out of 5 average rating, 21 reviews

Home in High Springs

Charming Downtown High Springs Retreat. 3BR/2BA

5 out of 5 average rating, 43 reviews

A welcoming living area features a spacious sectional sofa in soft beige, complemented by a light wooden ceiling and recessed lighting. A large television is mounted on a white console, while a dining table with black chairs is positioned nearby. Glass doors provide access to the outdoor deck.

Home in Fort White

Cozy 3 Bdrm Cottage Retreat by the Springs

4.97 out of 5 average rating, 79 reviews

A quaint outdoor area features a rustic white picket fence and a vintage turquoise bicycle positioned beside a blooming vine-covered trellis. The charming structure enhances the serene yard, with hints of colorful flowers adding to the inviting atmosphere.

Home in Live Oak

Quiet Cottage on 41-Acre Farm | Private Front Acre

A vibrant living area features plush green sofas and yellow accent chairs, arranged around a coffee table. A red accent wall enhances the space, while a flat-screen TV is mounted for entertainment. Light streams in through window treatments, creating an inviting atmosphere.

4.89 out of 5 average rating, 65 reviews

The Velvet Rose

Superhost

A modern kitchen space is showcased, featuring gray cabinetry and stainless-steel appliances. A dining table with black chairs occupies the center, illuminated by recessed lighting. Natural light enters through a window that overlooks greenery, enhancing the room's inviting atmosphere.

4.69 out of 5 average rating, 32 reviews

Creekside

5 out of 5 average rating, 37 reviews

Lakefront Retreat - Pickett Lake

The exterior of the home features a welcoming façade with a maroon front door framed by decorative plants. A pathway leads to the entrance, bordered by stone landscaping. The property is set on a lush green lawn surrounded by trees under a clear blue sky.