Hotels in Key West

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Top-rated hotels in Key West

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Guest favorite
Hotel room in Key West
4.88 out of 5 average rating, 672 reviews

The Sanchez House Room #3

There is no better welcome to Key West than staying in local and famous folk artist Mario Sanchez's birth home. This home was built in the 1860's in the heart of the historic Gato and Merrero cigar factory villages. Featuring original Dade County pine construction, and located right on historic Duval Street, the Sanchez House is guaranteed to offer the historic atmosphere and living a part of Key West many visitors want to experience. Sit on the balcony and enjoy the trade winds & Ocean Breeze.

Guest favorite
A well-appointed room features a spacious bed adorned with colorful pillows. Large windows with decorative glass let in natural light, illuminating the warm yellow walls. A flat-screen TV and stylish furniture create a cozy atmosphere, while decorative artwork enhances the aesthetic appeal.
Hotel room in Key West
4.97 out of 5 average rating, 39 reviews

Marrero's Guest Mansion Adult Only (21+) Room 6

Adult Only Boutique Hotel (21+). Experience the grandeur of the stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. This room features one king bed and a full private bath located on the second floor of the mansion. This room is home to the largest veranda in the house and provides guests with a fantastic view of Fleming Street - perfect for relaxing, people watching, or enjoying a drink as you unwind. Also features a room with closet for extra storage.

Superhost
Hotel room in Key West

Hyatt Sunset Harbor Key West 1 BR,1 BA Mallory Sq

Hyatt Residence Club Sunset Harbor has the best location in the heart of Key West’s famed Old Town. Walk to Mallory Square & all the bars/restaurants around Duval Street. Private 1 Bedroom unit sleeps 4. Offers Queen sized bed and Queen size Sleep sofa. Hallway bathroom with sink and shower/tub combo., TV, WIFI, full kitchen, utensils for 4 and large balcony. Resort has shared pool, hot tub, BBQ grills, laundry machines for guest use. Easy walk or public transport to Key West attractions!

Hotel room in Key West
5 out of 5 average rating, 4 reviews

Steps to Duval St + Free Breakfast, Pool & Spa

Located at the quiet end of Duval Street, The Guesthouses at Southernmost Beach Resort offer an adult-focused sanctuary with a sophisticated Key West vibe. Guests enjoy "stay at one, play at all" access to the entire resort, including 3 pools, a private beach, and oceanfront bars. Walk to the Southernmost Point or relax in lush tropical gardens. Highlights include the beach-chic decor, world-class spa, and daily breakfast, blending boutique intimacy with full-scale luxury amenities.

Guest favorite
A well-lit bedroom features a spacious bed with a light-colored quilt, complemented by two bedside tables with orange lamps. French doors open to a balcony overlooking lush greenery. A light blue wall adds a calm touch, while a white wicker chair is positioned near the window.
Hotel room in Key West
5 out of 5 average rating, 19 reviews

Aquamarine Deluxe King

***21 and up*** Enjoy this charming hotel located 2 blocks from the Historic Wharf and 4 blocks to Duval St. This room is just steps away from our main pool, and appointed with a king bed with a walk in shower, Keurig coffee maker, TV, patio, and mini fridge. Perfect romantic getaway for 2! It shares a small patio with the neighboring room. Our property sports 2 pools, lush gardens, sitting areas, complimentary breakfast, and all the amenities you would need to enjoy Key West!

Santa Maria Suites
4.9 out of 5 average rating, 20 reviews

Santa Maria Suites

Enjoy 910 sq. ft. of tropical modern living in this 2-bedroom, luxury bi-level suite. Upstairs bedrooms feature pillow-top queen beds, work desks, spacious closets, and spa-inspired separate bathrooms, one with a walk-in shower that includes a rainfall showerhead & the other with a full-sized bathtub. The suite includes a downstairs living area that comes with a comfortable queen-size sleeper sofa, guest powder room, and laundry area with both washer and dryer + pool view!

Superhost
The living area features a Murphy bed within a dark wooden cabinet, a modern black sofa, and a wooden coffee table. A flat-screen television is positioned on a side cabinet. Natural light enters through sliding glass doors that lead to a private balcony.
Hotel room in Marathon
4.72 out of 5 average rating, 87 reviews

Knight's Key Suites Premium Apartment w/Kitchen

One-of-a-kind place accommodations located next to the 7-Mile Bridge in the heart of the Florida Keys. This room features one king, one queen, and one Murphy bed that can accommodate up to six people. full kitchen. Dear guest, we’re sorry to inform you that, due to unexpected circumstances beyond our control, the pool will be closed until Monday 4/20/26. A significant leak was found and emergency repairs are necessary to fix the problem.

Superhost
Hotel room in Key West
New place to stay

In the heart of Key West + Resort Style Pool

Experience the vibrant spirit of Cuba in the heart of Key West at Havana Cabana, a waterfront retreat full of charm and character. Classic cars, refreshing mojitos, and lively poolside music set the tone for a nostalgic escape inspired by Cuban art and culture. From the moment you arrive, vintage cars shine in the Florida sun while Flamenco rhythms and the scent of hand‑rolled cigars welcome you into an atmosphere that feels worlds away.

Guest favorite
Hotel room in Key West
5 out of 5 average rating, 32 reviews

Luxury King Studio – Come Hide at Key West Hotel

Welcome to The Key West Hotel—ideally located on Duval Street yet tucked away in a private oasis. Choose from charming rooms in a restored Victorian conch house or a modern poolside retreat, all surrounding a lush courtyard and sparkling pool. Guests can unwind at the exclusive Bali Bar, a tiki-style hideaway serving handcrafted island cocktails with live local music each night. It’s the perfect blend of relaxation and Key West energy.

Hotel room in Key West
4.68 out of 5 average rating, 101 reviews

Minutes to Duval + Free Breakfast. Newly Renovated

Escape to island charm and sunshine at this Hotel in Key West, your relaxing coastal retreat just minutes from Old Town and the airport. Wake up to complimentary breakfast, unwind at the tropical outdoor pool and tiki bar, or rent a bike to explore palm-lined streets and colorful coastal sights. Whether you’re here for adventure or leisure, this hotel blends laid-back comfort with all the essentials for a perfect Key West getaway.

The image features a multi-story resort building painted in pastel colors, accented by a large blue flamingo mural. A spacious pool is situated in the foreground, surrounded by palm trees and lounge chairs, under a bright blue sky with scattered clouds.
Hotel room in Key West
4.67 out of 5 average rating, 205 reviews

Close to Smathers Beach + Pool. Dining. Shuttle.

Cruise to the beach, nap in the sun, and live like a local at Blue Flamingo Resort Key West. Just minutes from Duval Street, this chill island stay has everything you need—bikes, a breezy pool, and a colorful vibe that feels more like a friend’s place than a resort. Bring your pup, stash the car, and spend your days hopping between beaches, seafood shacks, and sunset spots. Here, the only agenda is island time.

H2O Suites
5 out of 5 average rating, 4 reviews

H2O Suites

Enjoy a stylish suite with a private balcony overlooking the tropical courtyard and sea breeze. Relax in a spacious living area, a king bed, and a luxurious Italian marble bathroom with dual sinks, a separate vanity, and a rainfall shower. This suite is designed for comfort and tranquility.

Popular amenities for Key West hotels

When is the best time to visit Key West?

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Quick stats about hotels in Key West

  • Total vacation rentals

    Explore 360 vacation rentals in Key West

  • Nightly prices starting at

    Key West vacation rentals start at ﺩ.ﺇ624 per night before taxes and fees

  • Verified guest reviews

    Over 3,950 verified reviews to help you choose

  • Family-friendly vacation rentals

    70 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 110 rentals that welcome pets

  • Vacation rentals with a pool

    360 properties feature pools

  • Rentals with dedicated workspaces

    160 properties have a dedicated workspace

  • Wi-Fi availability

    360 of Key West vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Key West rentals

  • 4.6 Average rating

    Key West stays receive an average rating of 4.6 out of 5 from guests

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