Boutique hotels in Key West

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Top-rated boutique hotels in Key West

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

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Guest favorite
A bright cabana room features a spacious bed adorned with colorful pillows. Large glass doors open to a view of the pool area, allowing natural light to brighten the space. Vibrant floral wallpaper complements the light tones of the decor, contributing to a tropical ambiance.
Hotel room in Key West
4.96 out of 5 average rating, 68 reviews

Marrero's Guest Mansion Adult Only (21+) Room 12

Adult Only Boutique Hotel (21+). Experience the grandeur of their stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. We are located in the heart of Old Town, just half a block from Duval Street. This beautiful room is right next to our revitalizing saltwater-treated pool. Separate from the main house, this cabana room offers guests a more private tropical escape. This room features a pillow top king bed with a private bath and sitting area.

Top guest favorite
A waterfront rental property is shown, featuring a two-story building painted in a soft peach hue. Several palm trees frame the scene, while wooden docks extend into the calm waters. A spacious balcony overlooks the dock area, providing access to the scenic Florida Bay.
Hotel room in Duck Key
5 out of 5 average rating, 38 reviews

Conch Key Villas #1. Fun, fishing & great sunsets

Studio One's waterfront rental is located on the ground level. Our units differ vastly from other Florida Keys lodgings because our property is right on Florida Bay. If you trailer your boat, the dockage is a few feet from the back door. Our docks can handle boats up to 25’ and you can park your trailer in our front lot. There is a boat ramp just two blocks away. Studio 1 can sleep 2 adults and one child (up to 12 years). We have a king size bed and a futon.

Top guest favorite
Hotel room in Key West
4.89 out of 5 average rating, 483 reviews

Mallory House Room #3

There is no better place for your Key West stay than Mallory House. This historic circa 1890’s home is located on Duval Street in the Gato Cigar Factory Village. Mallory House is steps away from famous attractions, restaurants, cafés, bars and shops. Stay within close proximity to the Southernmost point and beach, the Hemingway house and lighthouse. Enjoy a complimentary cup of coffee on our spacious balcony overlooking world famous Duval Street.

A private oceanview terrace is presented, furnished with two comfortable chairs and a round table. Lush palm trees are visible in the background, framing the serene view of the ocean. Natural light enhances the welcoming atmosphere of this outdoor space.
Hotel room in Marathon

Marathon Oceanfront | ADA Queen + 5 Pools

Experience comfort and accessibility in the Oceanfront Balcony Queen ADA room. Designed for a seamless stay, this ADA-compliant retreat features a queen bed, a fully accessible deluxe bathroom, and a private oceanview terrace. Thoughtful details like wide doors, roll-in shower, and hearing-impaired features ensure ease and relaxation. Enjoy five pools, beachfront dining, and oceanfront luxury in the heart of the Florida Keys.

Superhost
The room features two wooden beds with crisp white linens and a contemporary design. Natural light enters through glass doors leading to a balcony. A comfortable chair is positioned beside a flat-screen TV and a wooden dresser, adding to the room's serene ambiance.
Hotel room in Marathon
4.89 out of 5 average rating, 109 reviews

Wreckers House Double Queen Room - Adults Only

Adults-only building, available for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

The entrance of The Paradise Inn is framed by lush palm trees and tropical vegetation. A welcoming sign indicates availability, while the charming architecture features a covered porch with ambient lighting, creating an inviting facade for guests arriving at night.
Hotel room in Key West
4.88 out of 5 average rating, 25 reviews

Gumbo Limbo Cottage

Experience all that our historical island has to offer while being able to unwind and relax in our historic Key West Inn, exclusive adult-only. With a refreshing pool area and shaded patios, you won’t have to leave our beautiful boutique-style Inn to feel like you are in a tropical haven. Lounge under the palms while sipping your beverage of choice, or take a dip in the inviting waters of the pool or hot tub.

Superhost
A spacious room features a large wooden bed with crisp white bedding. Light from a sliding glass door illuminates the space, revealing a view of palm trees and the outdoors. A ceiling fan and two bedside lamps provide ambient lighting, with a small desk and seating area visible.
Hotel room in Marathon
4.85 out of 5 average rating, 290 reviews

Wreckers House King Room - Adults Only

Adults-only building for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

A well-lit room features two sets of bunk beds with white linens, offering a clean and modern design. A red phone is mounted on the wall, while a wooden chair with a woven seat is positioned on the carpeted floor, providing additional seating.
Hotel room in Key West
4.67 out of 5 average rating, 9 reviews

NYAH 2 Bedroom Suite w Breakfast

PRIVATE ROOM IN A BOUTIQUE HOTEL - Adults only concept, just a few steps away from world-famous Duval Street, the head-turning Gulf, and countless eateries and shops. As our guests, you would also have access to our three pools, a jacuzzi, a small fleet of bicycle rentals, high-speed Wi-Fi, a continental breakfast bar, and complimentary 24-hour Starbucks coffee. Don't forget about our HAPPY HOUR!

An expansive pool, bordered by palm trees, reflects the vibrant sky at sunset. Sun loungers, arranged under white umbrellas, provide ample relaxation space. The backdrop features a building, offering a serene atmosphere for guests to unwind by the water.
Hotel room in Duck Key
5 out of 5 average rating, 3 reviews

Family Room in Duck Key | Sauna, Kayak & Pools

Gather the crew in the Family Oasis—a bright, roomy hideaway where bunk beds delight the kids and a plush king bed welcomes parents. Ideal for up to five guests, this relaxing space blends laid-back comfort with family-ready convenience. Located in Hawks Cay Resort, enjoy a full day of waterside fun, unwind in your oversized room, and let island time set the pace for your unforgettable stay.

A sparkling outdoor swimming pool is framed by swaying palm trees and lush tropical plants. Sun loungers are arranged around the pool area, providing ample space for relaxation. The backdrop features a charming white building with balconies and blue accents, creating a serene atmosphere.
Hotel room in Key West
4.91 out of 5 average rating, 11 reviews

2BR Unit, Enjoy Paradise with On-site Pools!

Step into a world of white sands and glimmering pools, where boat drinks and watersports are just steps from your front door. Explore vibrant Duval Street's shops and nightlife. Lounge at Smathers Beach via our complimentary shuttle. Immerse in historic Old Town Key West's charm. Adventure with kayaking and water sports, then unwind at our four pools. Your ideal Key West getaway awaits!

A bright room features a spacious bed with a light wood headboard and crisp white linens. A round dining table with two chairs sits beside the bed. Natural light enters through large windows adorned with sheer curtains, and a pendant light adds a modern touch.
Hotel room in Key West
4.57 out of 5 average rating, 54 reviews

Parrot Key, Garden 2 Bedroom Suite w/ Living Room

The island life awaits you at the Parrot Key Hotel and Villa in Key West. The Island getaway has an authentic ambiance with locally-inspired rooms and views of the Gulf of Mexico. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12.5%) and facility fee ($51 resort fee + 12.5% tax + $30 valet fee) will be charged upon arrival.

Superhost
A serene outdoor area is framed by lush greenery, featuring a charming archway leading to a small pool. Surrounding plant life adds a tropical feel, while the blue water glimmers in the sunlight, inviting relaxation amidst the natural backdrop.
Hotel room in Key West
5 out of 5 average rating, 3 reviews

Historic Cigar Barons Mansion

Upscale historic cigar barons mansion in walking distance to everything you desire in Key West. 3 spacious 1Br’s with outdoor living at its finest. Each guest suite has its own separate entrance to the gardens. pool, sitting areas, BBQ, 2 off street parking spaces, free laundry and Wi-Fi.

Popular amenities for Key West boutique hotels

When is the best time to visit Key West?

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Avg. priceﺩ.ﺇ1,333ﺩ.ﺇ2,013ﺩ.ﺇ1,517ﺩ.ﺇ1,245ﺩ.ﺇ1,421ﺩ.ﺇ1,061ﺩ.ﺇ1,109ﺩ.ﺇ911ﺩ.ﺇ793ﺩ.ﺇ929ﺩ.ﺇ1,285ﺩ.ﺇ1,385
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Quick stats about boutique hotels in Key West

  • Total vacation rentals

    Explore 50 vacation rentals in Key West

  • Nightly prices starting at

    Key West vacation rentals start at ﺩ.ﺇ514 per night before taxes and fees

  • Verified guest reviews

    Over 2,190 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    50 of Key West vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Key West rentals

  • 4.7 Average rating

    Key West stays receive an average rating of 4.7 out of 5 from guests

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