
Boutique hotels in Key West
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Key West
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Marrero's Guest Mansion Adult Only (21+) Room 12
Adult Only Boutique Hotel (21+). Experience the grandeur of their stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. We are located in the heart of Old Town, just half a block from Duval Street. This beautiful room is right next to our revitalizing saltwater-treated pool. Separate from the main house, this cabana room offers guests a more private tropical escape. This room features a pillow top king bed with a private bath and sitting area.

Conch Key Villas #1. Fun, fishing & great sunsets
Studio One's waterfront rental is located on the ground level. Our units differ vastly from other Florida Keys lodgings because our property is right on Florida Bay. If you trailer your boat, the dockage is a few feet from the back door. Our docks can handle boats up to 25’ and you can park your trailer in our front lot. There is a boat ramp just two blocks away. Studio 1 can sleep 2 adults and one child (up to 12 years). We have a king size bed and a futon.

Mallory House Room #3
There is no better place for your Key West stay than Mallory House. This historic circa 1890’s home is located on Duval Street in the Gato Cigar Factory Village. Mallory House is steps away from famous attractions, restaurants, cafés, bars and shops. Stay within close proximity to the Southernmost point and beach, the Hemingway house and lighthouse. Enjoy a complimentary cup of coffee on our spacious balcony overlooking world famous Duval Street.

Marathon Oceanfront | ADA Queen + 5 Pools
Experience comfort and accessibility in the Oceanfront Balcony Queen ADA room. Designed for a seamless stay, this ADA-compliant retreat features a queen bed, a fully accessible deluxe bathroom, and a private oceanview terrace. Thoughtful details like wide doors, roll-in shower, and hearing-impaired features ensure ease and relaxation. Enjoy five pools, beachfront dining, and oceanfront luxury in the heart of the Florida Keys.

Wreckers House Double Queen Room - Adults Only
Adults-only building, available for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

Gumbo Limbo Cottage
Experience all that our historical island has to offer while being able to unwind and relax in our historic Key West Inn, exclusive adult-only. With a refreshing pool area and shaded patios, you won’t have to leave our beautiful boutique-style Inn to feel like you are in a tropical haven. Lounge under the palms while sipping your beverage of choice, or take a dip in the inviting waters of the pool or hot tub.

Wreckers House King Room - Adults Only
Adults-only building for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

NYAH 2 Bedroom Suite w Breakfast
PRIVATE ROOM IN A BOUTIQUE HOTEL - Adults only concept, just a few steps away from world-famous Duval Street, the head-turning Gulf, and countless eateries and shops. As our guests, you would also have access to our three pools, a jacuzzi, a small fleet of bicycle rentals, high-speed Wi-Fi, a continental breakfast bar, and complimentary 24-hour Starbucks coffee. Don't forget about our HAPPY HOUR!

Family Room in Duck Key | Sauna, Kayak & Pools
Gather the crew in the Family Oasis—a bright, roomy hideaway where bunk beds delight the kids and a plush king bed welcomes parents. Ideal for up to five guests, this relaxing space blends laid-back comfort with family-ready convenience. Located in Hawks Cay Resort, enjoy a full day of waterside fun, unwind in your oversized room, and let island time set the pace for your unforgettable stay.

2BR Unit, Enjoy Paradise with On-site Pools!
Step into a world of white sands and glimmering pools, where boat drinks and watersports are just steps from your front door. Explore vibrant Duval Street's shops and nightlife. Lounge at Smathers Beach via our complimentary shuttle. Immerse in historic Old Town Key West's charm. Adventure with kayaking and water sports, then unwind at our four pools. Your ideal Key West getaway awaits!

Parrot Key, Garden 2 Bedroom Suite w/ Living Room
The island life awaits you at the Parrot Key Hotel and Villa in Key West. The Island getaway has an authentic ambiance with locally-inspired rooms and views of the Gulf of Mexico. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12.5%) and facility fee ($51 resort fee + 12.5% tax + $30 valet fee) will be charged upon arrival.

Historic Cigar Barons Mansion
Upscale historic cigar barons mansion in walking distance to everything you desire in Key West. 3 spacious 1Br’s with outdoor living at its finest. Each guest suite has its own separate entrance to the gardens. pool, sitting areas, BBQ, 2 off street parking spaces, free laundry and Wi-Fi.
Popular amenities for Key West boutique hotels
Family-friendly boutique hotels

Poolside Room w/ Spa & Tiki Beach | No Hidden Fee

Poolside Room w/ Kayak & Sauna | No Hidden Fee!

King ADA w/ Views in Duck Key | Marina, Spa & Pool

Marathon Beachfront | 2 Queens + Veranda

ADA Room w/ Views, Spa & Water Fun | No Hidden Fee

Southernmost Inn Private Deluxe King Room with Breakfast

Marathon Beachfront | 2BR, Veranda + 2 Luxe Baths

Duck Key Trip! | ADA Family Rm w/ Snorkeling + Spa
Boutique hotels with a patio

Conch Key Villas #2 Peaceful waterfront lodging

Marrero's Guest Mansion Adult Only (21+) Room 11

Marrero's Guest Mansion Adult Only (21+) Room 10

Galleon King Suite - Adults Only
Other boutique hotel vacation rentals

Perfect for a Relaxing Getaway w/ Free Breakfast

Marathon Oceanfront | 2 King Beds + Balcony

Dbl Queen Room | Pool, Spa & Kayak | No Hidden Fee

Marathon Beachfront | King Bed + Veranda

Water View King Rm in Duck Key | Spa, Kayak & Pool

Two Bedroom Suite

Marathon Beachfront | 2Kings, Veranda + 2LuxeBaths

Tropical Duck Key Escape! | King Rm w/ Pools & Spa
When is the best time to visit Key West?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ1,333 | ﺩ.ﺇ2,013 | ﺩ.ﺇ1,517 | ﺩ.ﺇ1,245 | ﺩ.ﺇ1,421 | ﺩ.ﺇ1,061 | ﺩ.ﺇ1,109 | ﺩ.ﺇ911 | ﺩ.ﺇ793 | ﺩ.ﺇ929 | ﺩ.ﺇ1,285 | ﺩ.ﺇ1,385 |
| Avg. temp | 21°C | 22°C | 24°C | 25°C | 27°C | 29°C | 30°C | 30°C | 29°C | 27°C | 25°C | 23°C |
Quick stats about boutique hotels in Key West

Total vacation rentals
Explore 50 vacation rentals in Key West

Nightly prices starting at
Key West vacation rentals start at ﺩ.ﺇ514 per night before taxes and fees

Verified guest reviews
Over 2,190 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
50 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
50 of Key West vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Key West rentals

4.7 Average rating
Key West stays receive an average rating of 4.7 out of 5 from guests
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