Boutique hotels in Key West

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Top-rated boutique hotels in Key West

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

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Top guest favorite
The room features a queen size bed with a light green patterned comforter. A flat screen TV is mounted on the wall opposite, alongside a small white table and lamp. Natural light enters through a window with sheer curtains, complemented by artwork on the walls.
Hotel room in Key West
4.95 out of 5 average rating, 61 reviews

Speakeasy Inn - Room 1B (1 Queen Bed)

This room sleeps 2 and has a queen size bed. It is located upstairs behind Room 1A with a sitting area on the wrap around balcony. This room has a private bath with shower, hair dryer and a clawfoot bathtub. The kitchenette is equipped with a refrigerator, microwave, toaster, coffee maker and dishware. A flat screen TV with cable channels, WiFi, individual A/C and iron and ironing board are among the many amenities in this room. Parking available on a first come first serve basis.

Guest favorite
A bright cabana room features a spacious bed adorned with colorful pillows. Large glass doors open to a view of the pool area, allowing natural light to brighten the space. Vibrant floral wallpaper complements the light tones of the decor, contributing to a tropical ambiance.
Hotel room in Key West
4.97 out of 5 average rating, 59 reviews

Marrero's Guest Mansion Adult Only (21+) Room 12

Adult Only Boutique Hotel (21+). Experience the grandeur of their stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. We are located in the heart of Old Town, just half a block from Duval Street. This beautiful room is right next to our revitalizing saltwater-treated pool. Separate from the main house, this cabana room offers guests a more private tropical escape. This room features a pillow top king bed with a private bath and sitting area.

Top guest favorite
A waterfront rental property is shown, featuring a two-story building painted in a soft peach hue. Several palm trees frame the scene, while wooden docks extend into the calm waters. A spacious balcony overlooks the dock area, providing access to the scenic Florida Bay.
Hotel room in Duck Key
5 out of 5 average rating, 34 reviews

Conch Key Villas #1. Fun, fishing & great sunsets

Studio One's waterfront rental is located on the ground level. Our units differ vastly from other Florida Keys lodgings because our property is right on Florida Bay. If you trailer your boat, the dockage is a few feet from the back door. Our docks can handle boats up to 25’ and you can park your trailer in our front lot. There is a boat ramp just two blocks away. Studio 1 can sleep 2 adults and one child (up to 12 years). We have a king size bed and a futon.

Guest favorite
Hotel room in Key West
4.89 out of 5 average rating, 461 reviews

Mallory House Room #3

There is no better place for your Key West stay than Mallory House. This historic circa 1890’s home is located on Duval Street in the Gato Cigar Factory Village. Mallory House is steps away from famous attractions, restaurants, cafés, bars and shops. Stay within close proximity to the Southernmost point and beach, the Hemingway house and lighthouse. Enjoy a complimentary cup of coffee on our spacious balcony overlooking world famous Duval Street.

Superhost
The room features two wooden beds with crisp white linens and a contemporary design. Natural light enters through glass doors leading to a balcony. A comfortable chair is positioned beside a flat-screen TV and a wooden dresser, adding to the room's serene ambiance.
Hotel room in Marathon
4.91 out of 5 average rating, 101 reviews

Wreckers House Double Queen Room - Adults Only

Adults-only building, available for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

A well-lit room features two sets of bunk beds with white linens, offering a clean and modern design. A red phone is mounted on the wall, while a wooden chair with a woven seat is positioned on the carpeted floor, providing additional seating.
Hotel room in Key West
4.4 out of 5 average rating, 5 reviews

NYAH 2 Bedroom Suite w Breakfast

PRIVATE ROOM IN A BOUTIQUE HOTEL - Adults only concept, just a few steps away from world-famous Duval Street, the head-turning Gulf, and countless eateries and shops. As our guests, you would also have access to our three pools, a jacuzzi, a small fleet of bicycle rentals, high-speed Wi-Fi, a continental breakfast bar, and complimentary 24-hour Starbucks coffee. Don't forget about our HAPPY HOUR!

A sparkling outdoor swimming pool is framed by swaying palm trees and lush tropical plants. Sun loungers are arranged around the pool area, providing ample space for relaxation. The backdrop features a charming white building with balconies and blue accents, creating a serene atmosphere.
Hotel room in Key West
4.91 out of 5 average rating, 11 reviews

2BR Unit, Enjoy Paradise with On-site Pools!

Step into a world of white sands and glimmering pools, where boat drinks and watersports are just steps from your front door. Explore vibrant Duval Street's shops and nightlife. Lounge at Smathers Beach via our complimentary shuttle. Immerse in historic Old Town Key West's charm. Adventure with kayaking and water sports, then unwind at our four pools. Your ideal Key West getaway awaits!

The Cabana Inn is framed by a wooden fence and surrounded by lush greenery. The two-story building displays a traditional architectural style with a wide front porch, inviting guests to enter. Pathways of stone lead toward the entrance, enhancing the property's charm.
Hotel room in Key West
4.5 out of 5 average rating, 136 reviews

Cabana Inn 2 Bedroom Suite with Breakfast

When tropical oasis meets Duval Street, you know you have arrived at the Cabana Inn. Located just a block from Duval Street, our adult-only Key West inn is hidden amongst the shady trees to create a tranquil paradise. The historic conch estate, with cottages that were meticulously converted into a comfortable Key West hotel, features modern designs throughout the interior and exterior.

A bright room features a spacious bed with a light wood headboard and crisp white linens. A round dining table with two chairs sits beside the bed. Natural light enters through large windows adorned with sheer curtains, and a pendant light adds a modern touch.
Hotel room in Key West
4.57 out of 5 average rating, 54 reviews

Parrot Key, Garden 2 Bedroom Suite w/ Living Room

The island life awaits you at the Parrot Key Hotel and Villa in Key West. The Island getaway has an authentic ambiance with locally-inspired rooms and views of the Gulf of Mexico. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12.5%) and facility fee ($51 resort fee + 12.5% tax + $30 valet fee) will be charged upon arrival.

An outdoor terrace overlooks the ocean, featuring a glass-topped table and comfortable seating. Lush palm trees sway gently in the breeze, and the tranquil waters glisten under bright sunlight, creating a serene backdrop to the private retreat.
Hotel room in Marathon

Marathon Oceanfront Suite | Balcony + 2 Luxe Baths

Experience breathtaking oceanfront luxury in the Oceanfront Balcony | 2BR 2Qns room. Featuring a king bed, two queen beds, and two deluxe bathrooms, this spacious retreat is perfect for families or groups. Relax on the private oceanview terrace, enjoy modern comforts, and indulge in five pools, beachside dining, and endless adventures.

Superhost
A tranquil outdoor sitting area features two lounge chairs positioned on a brick patio surrounded by lush greenery. The blue pool is visible in the background, framed by palm trees and vibrant tropical plants, creating a serene environment for relaxation.
Hotel room in Key West
5 out of 5 average rating, 3 reviews

Historic Cigar Barons Mansion

Upscale historic cigar barons mansion in walking distance to everything you desire in Key West. 3 spacious 1Br’s with outdoor living at its finest. Each guest suite has its own separate entrance to the gardens. pool, sitting areas, BBQ, 2 off street parking spaces, free laundry and Wi-Fi.

A bright room features two spacious beds, each dressed in white linens. A small nightstand with a lamp sits between the beds, offering a viewing window that opens to a lush exterior landscape. Light-colored walls and natural light create an inviting atmosphere.
Hotel room in Marathon
4.76 out of 5 average rating, 113 reviews

Deluxe Two Double

This room has a queen bed, a double bed, refrigerator and microwave. It is located on the second floor of the guest building and is adjacent to a large deck that faces toward the aviaries and the landscape. Enjoy the free use of Kayaks.

Popular amenities for Key West boutique hotels

When is the best time to visit Key West?

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Quick stats about boutique hotels in Key West

  • Total vacation rentals

    Explore 60 vacation rentals in Key West

  • Nightly prices starting at

    Key West vacation rentals start at ﺩ.ﺇ514 per night before taxes and fees

  • Verified guest reviews

    Over 2,170 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Vacation rentals with a pool

    60 properties feature pools

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    60 of Key West vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Key West rentals

  • 4.6 Average rating

    Key West stays receive an average rating of 4.6 out of 5 from guests

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