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House vacation rentals in Guadalupe

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost
Home in Cañamero
4.83 out of 5 average rating, 18 reviews

Finca Romero · Home with barbecue and pool

The house is a detached home rented in its entirety, set in the heart of nature within the Villuercas‑Ibores‑Jara UNESCO Global Geopark. It is part of a 300‑hectare private forest estate, a very quiet and natural setting that is ideal for relaxing and exploring one of the most special areas in Extremadura.​ The accommodation has a bedroom with a double bed and a full en‑suite bathroom, as well as a second bedroom with two single beds and another full bathroom. The spacious 55 m² living‑dining room is very bright and also has a guest toilet with a WC and sink. The kitchen is separate and fully equipped, designed for both longer stays and weekend getaways.​ The house is part of a small complex of three semi‑detached homes that share a large communal pool with night lighting (20 x 7‑metre basin) and a spacious 900 m² relaxation area. Each accommodation has its own designated private lounging area with outdoor furniture, so you can enjoy the outdoors comfortably within the estate’s shared spaces. In addition, the complex has a communal outdoor barbecue area shared by the three homes, ideal for preparing meals and dinners outside during your stay.​ The location is perfect for exploring the area: Guadalupe is just 10 km away, and Trujillo, Cáceres and Mérida are all less than a 90‑minute drive. The village of Cañamero is 5 km away and offers all essential services such as supermarkets, a pharmacy, restaurants, banks and a health centre. Access is easy and flexible thanks to a self check‑in system with a key safe and code, which is provided before arrival.​

Top guest favorite
An outdoor dining area is shaded by a vine-covered pergola, featuring a stone wall and a table surrounded by four wooden chairs. Natural light filters through the leaves, creating a serene setting overlooking the garden.
Home in Villanueva de la Vera
4.98 out of 5 average rating, 48 reviews

Los Cipreses de Bocaloso

Traditional stone cottage with pool in Villanueva de la Vera. 6 guests, 3 bedrooms, 2 bathrooms. Lovely stone cottage set in a private finca of our Pure Spanish Horse stud of 16 hectares, with stunning views of the Gredos mountains. A comfortable open plan sitting/dining room, fully equipped kitchen, 3 double bedrooms and 2 bathrooms. A pretty rose and herb garden with an salt water alberca for swimming, shady sitting areas looking out to the valley below. Horseriding can be arranged locally.

Superhost
A vibrant red farmhouse is set amidst lush greenery, surrounded by scattered oak trees and rolling hills in the background. Grazing horses are seen in the foreground, adding to the serene countryside landscape.
Home in Montánchez
4.91 out of 5 average rating, 11 reviews

El Cortijo, a unique atmosphere with charm & style

Finca al-manzil, a farm in the magical Sierra de Montanchez, Extremadura, a wonderful part of Spain with plenty to see and do. This is a unique property full of character. A perfect summer holiday, spring break or winter retreat for families, friends or couples. Bird watching and walking in the sierra are exceptional. Total privacy in a world of it own within walled grounds. Really gorgeous private pool, exclusive access for cortijo and barn if rented, great unspoilt views of the countryside

Guest favorite
A bright kitchen area is highlighted by a wooden bar made from barrels, complemented by high stools. A countertop is visible along one wall, featuring a microwave and sink. A foosball table is positioned in the foreground, with warm yellow walls adding to the inviting ambiance.
Home in Orellana de la Sierra
4.86 out of 5 average rating, 44 reviews

House in the Orellana swamp

Very close to the beach, with Wi-Fi. The house has a great view of the Orellana swamp and the region of La Serena, a porch with garden furniture, a patio with a barbecue and a cellar with a fireplace. Orellana de la Sierra is a small town of 200 inhabitants, typical of Extremadura Siberia, where you can enjoy a swimming area, water sports and fishing. You can admire the great variety of birds in the area and one of the most important crane camps in Extremadura.

Guest favorite
Home in Calera y Chozas
4.9 out of 5 average rating, 52 reviews

Casa VAS ~ private pool 15 km from Talavera

Disconnect from the routine in this traditional, unique and cozy village house. Castilla la Mancha has a richness and quality in the skies that makes it an unparalleled destination for ASTRONOMICAL TOURISM Renovated, with all the current amenities, but respecting the original charm and essence, preserving its wooden ceiling and wide walls, which keeps the heat in winter and cool in summer. Peacefulness, disconnection and warmth are its main characteristics.

Top guest favorite
The exterior of a single-story house is presented, featuring a stucco facade with a light beige color. A covered entrance is visible, along with a window with decorative metal bars. Air conditioning units are mounted on the exterior wall, and the street is quiet with nearby gates.
Home in Alberche del Caudillo
4.96 out of 5 average rating, 100 reviews

Nice house with patio 9 km from Talavera

Take a break and unwind at this peaceful home in the village of Alberche, a young and cozy town 9 km away. From Talavera de la Reina. With all amenities. 3 bedrooms, patio, bathroom, kitchen and living room, with central heating radiators in all rooms. TV in the living room and 2 bedrooms, with AMAZON Prime movies and DISNEY+ included and the NETFLIX App. Parking near the house is almost always possible, and if the car is not very large it fits in the patio.

Guest favorite
Home in San Bartolomé de las Abiertas
4.81 out of 5 average rating, 31 reviews

Casa Ayala with Private Saltwater Pool and BBQ

Welcome to Casa Ayala, a private villa for up to 8 guests — designed to disconnect, slow down and enjoy quality time with family or friends, with all the comforts you need. What makes this place special is the experience: - Private 8×4 m saltwater pool - 200 m² private patio - Barbecue and chill‑out areas - Air conditioning in every room (hot & cold) A warm, inviting atmosphere Casa Ayala is not just accommodation… it’s a place to live and feel.

Superhost
A fully equipped kitchen is highlighted by patterned tile floors and wooden beams. The space features a dining table with four chairs, modern appliances, and an open layout that allows for easy movement. Natural light enters through the doorway leading to the patio.
Home in Trujillo
4.92 out of 5 average rating, 52 reviews

CasaTrujillo Apartment

Casa Trujillo is located in Trujillo, just a 3-minute walk from the Plaza Mayor, and offers accommodation for up to 4 people, with a terrace (patio) and free Wi-Fi. It has 2 bedrooms, a living room, a fully-equipped kitchen with a microwave and coffee maker, and a bathroom with a shower and hairdryer. Towels and bedding are provided. In addition, the accommodation is equipped with air conditioning and heating. Registration number: AT-CC-00419.

Guest favorite
An inviting patio features a shaded seating area with a brown sofa and coffee table, surrounded by light-colored walls. A tree is centrally positioned, providing natural ambiance to the outdoor space, which is paved with neutral-toned tiles.
Home in Navalvillar de Pela
4.94 out of 5 average rating, 18 reviews

La Casita de Pela

The house has three bedrooms with a double bed, a large kitchen, and a living room with a TV, sofa, and fireplace. In addition to a pleasant interior patio that allows you to enjoy pleasant evenings. Free parking. The house is in a strategic location, close to the most interesting places in this area of Extremadura such as: the Orellana Reservoir, Guadalupe, Trujillo, García Sola Reservoir, Mérida and Cáceres.

Guest favorite
A cozy bedroom features a spacious bed adorned with neutral-toned linens. Wooden beams line the ceiling, and soft lighting creates a calming ambiance. A wardrobe and nightstands provide functional storage, while a bottle of champagne and towels are elegantly arranged at the foot of the bed.
Home in Trujillo
4.86 out of 5 average rating, 278 reviews

Apartamentos "El Canyon de la Rinconada"

Apartments of about 100 m2 (Full rental), from 2 to 4 people, in the heart of the historic center of Trujillo, just a few meters from its main square. Fully furnished with everything you need for a great and cozy stay. Its location is unbeatable for strolling through streets full of history, and in 50 meters to the round you can find the best restaurants, gourmet shops and drink bars in the city.

Guest favorite
A cozy sleeping area features a spacious bed adorned with decorative pillows covered in rich, red and gold fabric. The intricately carved headboard adds a touch of elegance, while subtle lighting enhances the textures of the bedding.
Home in Escurial
4.88 out of 5 average rating, 34 reviews

Butterfly in the bell

Get away from the routine at this unique and relaxing stay. Located in the heart of a village of 900 inhabitants. It combines the traditional with modern touches to provide a cozy stay. Its room with a brick vault brings a feeling of warmth and solidity that plays with light and shadows. Its Moorish decoration contrasts with the views from its windows to a 17th-century church.

Superhost
Home in Cáceres
5.0 out of 5 average rating, 3 reviews

La Vera 4 Cabin

Get away from routine at this unique and relaxing stay. Enjoy the luxury of tranquility and being in the countryside without leaving the cabin. You have a beautiful region around you to enjoy if you want to explore. No fires or barbecues during the high fire risk period between May 27, 2026 and October 15, 2026

Popular amenities for Guadalupe house rentals