
Family-friendly vacation rentals in Downtown San Diego
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Downtown San Diego

Total vacation rentals
Explore 760 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 33,700 verified reviews to help you choose

Pet-friendly vacation rentals
Find 240 rentals that welcome pets

Vacation rentals with a pool
230 properties feature pools

Rentals with dedicated workspaces
480 properties have a dedicated workspace

Wi-Fi availability
760 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Downtown San Diego
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

Artifact Inn - Historic Deluxe Studio in Downtown
The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.

Gorgeous 2Bd Corner Bungalow in Little Italy
Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

City View Banker's Hill
A beautifully renovated 2-bedroom, 1.5-bathroom craftsman-style duplex is perfectly situated in the heart of Bankers Hill. The perfect blend of classic craftsmanship and modern amenities in this beautifully restored home. Minutes away from San Diego's top attractions, including Balboa Park, Little Italy, and the vibrant Gaslamp Quarter. Two comfortable bedrooms provide a peaceful retreat. Fully equipped kitchen with new appliances. A perfect place to enjoy all that San Diego has to offer.

Beautiful Historic Home and Gardens Near Downtown!
Location, Location, Location...Welcome to Union Street Gardens. We are dedicated to providing a peaceful, serene atmosphere in which our guests can relax after a long day of exploring beautiful, sunny San Diego. This unique historic craftsman bungalow is just minutes from downtown, Balboa Park, the Zoo, beaches, and includes a Chef's kitchen, outdoor deck, gardens, fire pit and spa! Perfect for a family of 4 or two couples. Sorry no parties or large groups and no external guests please.

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Little Italy King Suite
A luxurious 1b/1b condo . The spacious living area includes a flat screen TV and large courtyard viewing window laced with marble tile. The peaceful bedroom features a king sized bed, SMART flat screen TV, and ample storage space. Experience San Diego in this prime Little Italy location . Walking distance to Water Front Park, Seaport Village, Embarcadero, and all of Little Italy. *No Parking Available After September 1, 2026.

At Mine | Spacious Suite in the Gaslamp Quarter
This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

King Size Luxury Loft Petco-Park-Downtown SD
Welcome to your private Downtown San Diego retreat! This beautifully renovated, ground-level loft features a private entrance, no lobby or shared hallways, a comfortable king bed, high ceilings, fully equipped kitchen, fast Wi-Fi, and Smart TV. Just steps from Petco Park, Gaslamp, the Convention Center, Little Italy, restaurants, cafés, and nightlife. Perfect for business, events, or a fun city scape.
Popular amenities for Downtown San Diego family-friendly rentals
Family-friendly home rentals with a hot tub

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

Pool Oasis in Central Hillcrest by Park/Zoo

Stylish San Diego Home with Hot Tub Near SDSU

Cozy University Heights Cottage

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Heated Pool|Jacuzzi|King Bed|City Views|Chic Decor

California Dreaming l Hot tub l Private Backyard

Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT
Family- and pet-friendly home rentals

The Cozy Craftsman

Luxury 7 BR Mission Hills Home with a View

Lux Villa: Heated Pool & Sauna

Urban Greenhouse

Beautiful Canyon Cottage located on a huge lot

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC

Modern 3-story Townhome|Free Parking|Walk to Petco

Little Italy 2BR Loft Near Waterfront & Convention
Family-friendly home rentals with a pool

Designer Luxury Rental With Pool

San Diego Pool House with Luxury King/Queen Suites

Upscale Resort House /Views, Saltwater Pool/Spa !

Heart of San Diego in Old Town. Private Oasis 6

Hillcrest canyon home casita with pool access

Heated Pool + Hot Tub | Games | 10 min to Beach

The Queen House

Cozy home central to beaches & attractions
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 735 | ﺩ.ﺇ 749 | ﺩ.ﺇ 815 | ﺩ.ﺇ 808 | ﺩ.ﺇ 830 | ﺩ.ﺇ 973 | ﺩ.ﺇ 970 | ﺩ.ﺇ 834 | ﺩ.ﺇ 753 | ﺩ.ﺇ 775 | ﺩ.ﺇ 797 | ﺩ.ﺇ 819 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Resort rentals Downtown San Diego
- Boutique hotels Downtown San Diego
- Rentals with breakfast Downtown San Diego
- House rentals Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Hotel rooms Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Balboa Park
- San Diego State University
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Sesame Place San Diego
- Belmont Park
- South Mission Beach, San Diego
- Liberty Station





