
Family-friendly vacation rentals in Downtown San Diego
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Downtown San Diego

Total vacation rentals
Explore 760 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 33,700 verified reviews to help you choose

Pet-friendly vacation rentals
Find 240 rentals that welcome pets

Vacation rentals with a pool
230 properties feature pools

Rentals with dedicated workspaces
480 properties have a dedicated workspace

Wi-Fi availability
760 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Downtown San Diego
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Designer Rental w/ FirePit- Petco Park, DT, + Zoo
Welcome to Our 1920s Designer Craftsman Apartment in San Diego’s Best Neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, + Conv Center :) *Washer&Dryer *High end Bedding *Easy Parking *Boutique hotel-like experience Fire pit, grills, and a cocktail/reading den! This stylish apartment is on the edge of the iconic Balboa Park, a short walk from the lively North Park scene, & 5-minute drive to the Gaslamp Quarter and airport. Beaches and Convention Center are only minutes away.

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Artifact Inn - Historic Deluxe Studio in Downtown
The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.

City View Banker's Hill
A beautifully renovated 2-bedroom, 1.5-bathroom craftsman-style duplex is perfectly situated in the heart of Bankers Hill. The perfect blend of classic craftsmanship and modern amenities in this beautifully restored home. Minutes away from San Diego's top attractions, including Balboa Park, Little Italy, and the vibrant Gaslamp Quarter. Two comfortable bedrooms provide a peaceful retreat. Fully equipped kitchen with new appliances. A perfect place to enjoy all that San Diego has to offer.

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Little Italy King Suite
A luxurious 1b/1b condo . The spacious living area includes a flat screen TV and large courtyard viewing window laced with marble tile. The peaceful bedroom features a king sized bed, SMART flat screen TV, and ample storage space. Experience San Diego in this prime Little Italy location . Walking distance to Water Front Park, Seaport Village, Embarcadero, and all of Little Italy. *No Parking Available After September 1, 2026.

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹
Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!

Bright & Modern OB Getaway
This newly built, 2 bedroom/2 bath, is the bright & airy, modern & stylish beach getaway you've been looking for! You'll be located 2 blocks from the beach, and are walking distance to a variety of different restaurants, coffee shops, yoga studios, and nightlife options. The rooftop deck provides an amazing panoramic view for catching sunsets, and even the Sea World fireworks show. Bikes and beach gear ready for use!

Grand Victorian Manor • Luxury Downtown Stay
Welcome to The Jade Manor, a 126 year old Victorian reborn as a dreamy San Diego escape. Set inside a gated, Parisian inspired tropical oasis, this home blends historic charm with modern luxury. Sun soaked spaces, elegant details, and celebration ready vibes make it perfect for bachelorette weekends, birthdays, and unforgettable group stays, while still feeling refined, private, and welcoming for all travelers.

At Mine | Spacious Suite in the Gaslamp Quarter
This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.
Popular amenities for Downtown San Diego family-friendly rentals
Family-friendly home rentals with a hot tub

Beautiful Historic Home and Gardens Near Downtown!

STUNNING MANSION THE BEST LOCATION & AMENITIES

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

Pool Oasis in Central Hillcrest by Park/Zoo

Stylish San Diego Home with Hot Tub Near SDSU

San Diego Oasis- A Retro Retreat w/ King Size Bed!

Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT
Family- and pet-friendly home rentals

The Cozy Craftsman

Downtown Dream 4

Little Italy 2BR Loft Near Waterfront & Convention

Modern 3-story Townhome|Free Parking|Walk to Petco

Beautiful Canyon Cottage located on a huge lot

Lux Villa: Heated Pool & Sauna

Urban Greenhouse

Ventana Vista | Ocean View | EV Charger | Designer
Family-friendly home rentals with a pool

Designer Luxury Rental With Pool

Private Heated Pool | Sleeps 10

The Queen House

Your Modern Lux Pool Resort in the Heart of SD

Lionhead - Private Boutique Home

Modern Central SD Home w/ Pool & Spa Near Beach

Relax in Style! 4BR Pool/Spa/Firepit – SuperHost

Hillcrest canyon home casita with pool access
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 735 | ﺩ.ﺇ 749 | ﺩ.ﺇ 815 | ﺩ.ﺇ 808 | ﺩ.ﺇ 830 | ﺩ.ﺇ 973 | ﺩ.ﺇ 970 | ﺩ.ﺇ 834 | ﺩ.ﺇ 753 | ﺩ.ﺇ 775 | ﺩ.ﺇ 797 | ﺩ.ﺇ 819 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Boutique hotels Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- House rentals Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Hotel rooms Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Liberty Station





