
House vacation rentals in Downtown San Diego
Find and book unique houses on Airbnb
Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 170 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 14,860 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Top 1% North Park Hot Tub Oasis Walkable
Enjoy an unforgettable stay in the vibrant neighborhood of North Park and learn why The Birdhouse is ranked in the top 1% worldwide! This oasis of relaxation offers a perfect blend of modern amenities, high-end decor and convenience. Enjoy a memorable bird theme, a huge patio with lux cabana and hot tub, and prime location with easy access to major attractions San Diego Zoo -8 min drive SeaWorld -12 min drive La Jolla Cove -18 min drive Book For Lasting Memories In North Park See Details Below

Designer unit w/FirePit: Petco Park, Zoo, Downtown
Welcome to our 1920's craftsman in San Diego's Best neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, Conv Center *Washer & Dryer *Thoughtfully Renovated *Boutique hotel-like experience Fire pit, grills, and outdoor dining area! This chic apartment is located on the edge of the iconic Balboa Park, and is walkable to trendy restaurants and bars. Less than a mile from the San Diego Zoo, mins to Gaslamp Quarter, Convention center, airport, and a 10 minute drive to beaches.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

Historic Golden Hill Post Office - 3 BR w fire pit
There isn't a more unique experience than staying at an old Post Office! The 3 br 2 bath unit was renovated in 2021 with high-end finishes, designer furniture & 2 WFH workspaces. The interior is flooded with natural light from skylights throughout with access to a large private patio with BBQ, fire pit, and dining table. Ideally located within the trendiest neighborhood in San Diego. Walk to an abundance of cafes, restaurants, bars, shops, & parks. Check it out at postofficelofts . com

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10
🏡 1,131 sq ft of curated interior space 🍳 Fully stocked kitchen 🛏️ 3 Queen Beds, 2 Twin Beds & 2 Twin Rollaway Beds 📺 Outdoor Lounge Area w/TV 🛁 Insta-worthy cast iron clawfoot hot tub — outdoors 🧺 Complimentary Washer & Dryer 🔒 Fully gated backyard 🚗 Private Parking (2 spots) 🏙️ 7 min to downtown 🦁 8 min to Zoo & Balboa Park ✈️ 12 min to airport & beach —>Want to enjoy the speakeasy? Just a heads-up—it’s not included in the base rate, but can be added for an additional fee!

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

NEW❤️Special Deals/HotTub/Firepit/private yard/BBQ
Located in the heart of Normal Heights, close to the City Center/Zoo/Balboa Park with access to all major Freeways. *1600 sqft Two-Story House *Private Backyard *Hot Tub *Fireplace *Central AC *10 mins to downtown *Fully stocked and equipped kitchen *Walk to coffee, yoga, gyms, dining, entertainment, shopping! NOTE: Bedroom #1 has a “bonus room” inside the Master bedroom (see pics). Message if you have any questions.

Modern ❤️ of South Park, SD skyline, private patio
- Newly renovated home - Historical neighborhood - Spacious front deck patio facing Dog Park - Skyline view of downtown San Diego - Extra large shower - Cozy bedding - Safe street parking - Dog friendly! $75 (2 pets max) Key landmarks - Balboa Park - Balboa Golf Course - 10 min walk to local favorite spots - 10 min drive to downtown San Diego - 15 min drive to SAN Airport
Popular amenities for Downtown San Diego house rentals
House rentals with a pool

Modern Central SD Home w/ Pool & Spa Near Beach

Beach<15min,Heated Pool,New Central AC, 4Br Family

Cozy University Heights Cottage

Your Modern Lux Pool Resort in the Heart of SD

Lionhead - Private Boutique Home

Designer Luxury Rental With Pool

Stunning 2BR/2BA| Plunge Pool, AC, Private

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

Bright & Modern OB Getaway

Hillcrest 2 bed 2 en-suite baths garage zen garden

The Island View Penthouse

Admire Harbor Views from the Porch at a City Gem

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹

Little Italy Historical

New Luxury 3BR/3.5BA Point Loma Coastal One Story

Pool Oasis in Central Hillcrest by Park/Zoo
Private house rentals

Prime location near downtown and Coronado island

Peaceful Jungle Retreat In The Heart of San Diego

Walk to Bars, Restaurants 1 BD Hillcrest, Parking

Dreamy Spanish Style Home w/ Large Yard + Hot Tub

Luxe & Cozy Getaway w/Skyline Views! 10 min to DT!

Walk to Little Italy Sleeps 8, Backyard + Parking

Panoramic Bay Views | Private Deck Bankers Hill

5 Min > Convoy | King Bed | Parking | Private Yard
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 738 | ﺩ.ﺇ 790 | ﺩ.ﺇ 859 | ﺩ.ﺇ 753 | ﺩ.ﺇ 830 | ﺩ.ﺇ 881 | ﺩ.ﺇ 1,025 | ﺩ.ﺇ 889 | ﺩ.ﺇ 804 | ﺩ.ﺇ 790 | ﺩ.ﺇ 786 | ﺩ.ﺇ 870 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Rentals with a fire pit Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Boutique hotels Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Hostel rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Hotel rooms Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Rentals with a patio Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- House rentals San Diego
- House rentals San Diego County
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- SeaWorld San Diego
- Rosarito Beach
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- San Diego State University
- Torrey Pines State Beach
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- La Misión Beach
- Moonlight State Beach
- Las Olas Resort & Spa
- Belmont Park
- Sesame Place San Diego
- Liberty Station
- South Mission Beach, San Diego





