
House vacation rentals in Downtown San Diego
Find and book unique houses on Airbnb
Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 140 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 14,210 verified reviews to help you choose

Family-friendly vacation rentals
100 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 50 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
140 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

Spacious 2bd/1bath House Near Downtown
Recently renovated 2bd/1bath house with outdoor area. Close to downtown, Gaslamp Quarter, 32nd Street Navy Base, and the convention center! The house shares the property with another house. The living room has a smart TV with HBO, Netflix, Hulu, and YouTube TV (w/Redzone). Nicely landscaped front yard and patio with lounge furniture, outdoor grill, and one gated off street parking spot. Have a group larger than 6? Book both houses on the property! https://www.airbnb.com/rooms/962337467912227108

Brunch House 3bd/2 Amazing Baths. Private yard.
Centrally located farmhouse with gated yard in vibrant urban neighborhood with Latin roots. Quick Uber to many SD tourist attractions: Chicano Park- 1.2 mi Balboa Park- 1.8 Gaslamp- 1.9 Petco Park Stadium- 1.9 Convention Center- 1.9 Seaport Village- 1.9 San Diego Zoo- 2.5 Little Italy- 3.8 Coronado Island- 3.9 Airport- 4.2 Old Town- 5.6 Ocean Beach- 7.9 Seaworld- 8.3 Mission Beach - 8.9 Pacific Beach- 9.9 La Jolla Beach- 13.8 Cabrillo National Park- 10.7 Close and convenient to EVERYTHING.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Convention Center | Petco Park | Free Parking
Amazing Vibe | Create Memories with this Gem in Barrio Logan next to Downtown, Coronado & the Beaches of SD. Sleeps 6 comfortably with 3 bedrooms. Full Kitchen, 2 Baths, TV, WorkSpace, Board Games, Laundry, & Grill + seating area. Uber drive to the nightlife downtown gaslamp, Petco Park, Convention Center, Airport, Zoo, Trendy Restaurants & less than 10 mins to the Beaches. Loc is close to Everything! Unsuitable for children 2-12 Unsuitable for infants No baby gear at the property

Modern House In The Hills | Killer Location!
Enjoy a stylish experience at this centrally-located, spacious 2 bedroom top floor retreat in lower Mission Hills, just 2 minutes north of Little Italy. Perched in one of the most prestigious & historic neighborhoods in San Diego. Be close to downtown, only 10 minutes to Mission Beach and centrally located for all the city has to offer. This is the perfect launching point to exploring San Diego, and coming home to this beautifully appointed home in this location is second to none.

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

San Diego House: City Views, BBQ & Free Parking!
Experience the best of San Diego living in our conveniently located Victorian home in the prestigious Banker’s Hill neighborhood. 🏡 The home boasts breathtaking views of the San Diego Bay and downtown skyline 🌊✨ from its private balconies, classic charm with original moldings, high ceilings, and hardwood floors, plus modern amenities like a fully equipped kitchen and dining area. 🍴 The location couldn’t be more perfect — steps to Balboa Park, Little Italy, and Downtown!

South Park Spanish Stunner Renovated & Central
Charming Spanish, newly renovated home and close to everything! Come stay in this brand new place with space for the whole gang! Arched windows and vaulted ceilings make it a beautiful light and bright space. Chef's kitchen ready for you to make big family meals. Great outdoor space to sit back and relax and enjoy the perfect SoCal weather. Central location to get anywhere within minutes while still being in a fun walkable neighborhood!
Popular amenities for Downtown San Diego house rentals
House rentals with a pool

La Jolla Beach House-Family Focused-3min to Beach

Resort Style Living with Pool, Spa, and Bay Views!

Cozy University Heights Cottage

Casa Bahia Beautiful San Diego Home with Pool

Your Modern Lux Pool Resort in the Heart of SD

Lionhead - Private Boutique Home

1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa

Designer Luxury Rental With Pool
Weekly house rentals

Historic Golden Hill Post Office - 3 BR w fire pit

New! Stunning Retreat Steps from Sunset Cliffs

Craftsman house in Southpark

Cozy 3 Bedroom in Ocean Beach

Tranquil Airy San Diego Home

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹

California Dreaming - Charming/Modern 2BD, 1 Bath

Spacious House close to Petco Park and Gaslamp
Private house rentals

Designer unit w/FirePit- Petco Park, Zoo, Downtown

Cozy family retreat with fenced yard

Peaceful Jungle Retreat In The Heart of San Diego

New, 3 Bed, 2 Bath Luxury, Central, Parking

Amazing Views - Central Location & Close to SDSU

Coastal Chic Retreat in Bankers Hill

Walk to Little Italy Sleeps 8, Backyard + Parking

Little Italy Studio: Private Patio Cozy Getaway
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 738 | ﺩ.ﺇ 790 | ﺩ.ﺇ 859 | ﺩ.ﺇ 753 | ﺩ.ﺇ 830 | ﺩ.ﺇ 881 | ﺩ.ﺇ 1,025 | ﺩ.ﺇ 889 | ﺩ.ﺇ 804 | ﺩ.ﺇ 790 | ﺩ.ﺇ 786 | ﺩ.ﺇ 870 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Rentals with a fire pit Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with a patio Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Waterfront rentals Downtown San Diego
- Hotel rooms Downtown San Diego
- Condo rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Boutique hotels Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- House rentals San Diego
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- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- San Diego Zoo
- Coronado Beach
- Torrey Pines State Beach
- Tijuana Beach
- Balboa Park
- San Diego State University
- LEGOLAND California
- Mission Beach
- La Misión Beach
- Moonlight State Beach
- Liberty Station
- Oceanside Harbor
- Sesame Place San Diego
- Belmont Park
- Black's Beach





