
House vacation rentals in Downtown San Diego
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Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 140 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 14,210 verified reviews to help you choose

Family-friendly vacation rentals
100 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 50 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
140 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

Stunning Grand Villa Dream Yard Amenities Location
Stunning Grand Villa in the perfect Location with Amazing Amenities!! Relax and recharge in this beautifully designed home featuring a hot tub, soaking tub, peaceful Zen garden, fully fenced yard, gated parking, luxury Posturepedic mattresses, grill, central A/C, fast WiFi, parking, and a fully stocked kitchen. Located In Marston Hill next to Balboa Park and the Zoo, minutes from San Diego’s top beaches and attractions, and walking distance to an incredible selection of restaurants and shops.

Designer unit w/FirePit- Petco Park, Zoo, Downtown
Welcome to our 1920's craftsman in San Diego's Best neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, Conv Center *Washer & Dryer *Thoughtfully Renovated *Boutique hotel-like experience Fire pit, grills, and outdoor dining area! This chic apartment is located on the edge of the iconic Balboa Park, and is walkable to trendy restaurants and bars. Less than a mile from the San Diego Zoo, mins to Gaslamp Quarter, Convention center, airport, and a 10 minute drive to beaches.

Brunch House 3bd/2 Amazing Baths. Private yard.
Centrally located farmhouse with gated yard in vibrant urban neighborhood with Latin roots. Quick Uber to many SD tourist attractions: Chicano Park- 1.2 mi Balboa Park- 1.8 Gaslamp- 1.9 Petco Park Stadium- 1.9 Convention Center- 1.9 Seaport Village- 1.9 San Diego Zoo- 2.5 Little Italy- 3.8 Coronado Island- 3.9 Airport- 4.2 Old Town- 5.6 Ocean Beach- 7.9 Seaworld- 8.3 Mission Beach - 8.9 Pacific Beach- 9.9 La Jolla Beach- 13.8 Cabrillo National Park- 10.7 Close and convenient to EVERYTHING.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Family-friendly fun in the sun
You will be close to everything San Diego has to offer in our cozy 2 bedroom 1 bathroom home. Family-friendly fully-gated yard with playset, mini putting green, games and seating area. Crib, changing pad, pack and play, 2 high chairs, child baths and dinnerware. Have a relaxing and fun time with multiple indoor games, large living room and bedroom smart TVs. Fast wifi, separate office space with desk, central heat/AC for comfort, W/D, 2 car driveway, lux bathroom and fully-equipped kitchen.

Award-Winning North Park 2BR on Balboa Park nr Zoo
★ Condé Nast rated top in SD ★ Luxury 2BR/1BA home w/ AC ★ Across the street from Balboa Park ★ 4 min to SD Zoo ★ 7 min walk to restaurants, cafes, breweries, shops, North Park entertainment corridor ★ 15 min to Beach ★ Washer/Dryer ★ Family-friendly space, pack n' play ★ Easy free street parking ★ Fully remodeled in 2022, professionally designed ★ Fresh artisan coffee, Nespresso ★ 4K TV, Netflix, HBO ★ We welcome people from all backgrounds ★ Security camera at exterior entry (none inside)

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10
🏡 1,131 sq ft of curated interior space 🍳 Fully stocked kitchen 🛏️ 3 Queen Beds, 2 Twin Beds & 2 Twin Rollaway Beds 📺 Outdoor Lounge Area w/TV 🛁 Insta-worthy cast iron clawfoot hot tub — outdoors 🧺 Complimentary Washer & Dryer 🔒 Fully gated backyard 🚗 Private Parking (2 spots) 🏙️ 7 min to downtown 🦁 8 min to Zoo & Balboa Park ✈️ 12 min to airport & beach —>Want to enjoy the speakeasy? Just a heads-up—it’s not included in the base rate, but can be added for an additional fee!

Modern House In The Hills | Killer Location!
Enjoy a stylish experience at this centrally-located, spacious 2 bedroom top floor retreat in lower Mission Hills, just 2 minutes north of Little Italy. Perched in one of the most prestigious & historic neighborhoods in San Diego. Be close to downtown, only 10 minutes to Mission Beach and centrally located for all the city has to offer. This is the perfect launching point to exploring San Diego, and coming home to this beautifully appointed home in this location is second to none.

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
Popular amenities for Downtown San Diego house rentals
House rentals with a pool

Your Modern Lux Pool Resort in the Heart of SD

Casa De Colores

Lionhead - Private Boutique Home

Bright and spacious home with views, pool & spa.

1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa

Designer Luxury Rental With Pool

Stunning 2BR/2BA| Plunge Pool, AC, Private

Luxe Home w. Serene Backyard Spa
Weekly house rentals

South Park Spanish Stunner Renovated & Central
Walk to Petco Park, Downtown, Gaslamp w/ garage!

Bankers Hill House | Bay & Downtown Views+Fire Pit

Luxe & Cozy Getaway w/Skyline Views! 10 min to DT!

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹

EpicViews | 3-Stories with Rooftop | Cortez Hill

5 Min > Convoy | King Bed | Parking | Private Yard

NEW❤️Special Deals/HotTub/Firepit/private yard/BBQ
Private house rentals

Prime location near downtown and Coronado island

Peaceful Jungle Retreat In The Heart of San Diego

California Dreaming 2-Charming/Modern 2BD, 1 Bath

Ventana Vista | Ocean View | EV Charger | Designer

Tranquil Airy San Diego Home

Walk to Little Italy Sleeps 8, Backyard + Parking

Spacious House close to Petco Park and Gaslamp

Cheerful 2 bedroom house in heart of San Diego
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 738 | ﺩ.ﺇ 790 | ﺩ.ﺇ 859 | ﺩ.ﺇ 753 | ﺩ.ﺇ 830 | ﺩ.ﺇ 881 | ﺩ.ﺇ 1,025 | ﺩ.ﺇ 889 | ﺩ.ﺇ 804 | ﺩ.ﺇ 790 | ﺩ.ﺇ 786 | ﺩ.ﺇ 870 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Hotel rooms Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Hostel rentals Downtown San Diego
- Rentals with a fire pit Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with a patio Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Boutique hotels Downtown San Diego
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- Condo rentals Downtown San Diego
- House rentals San Diego
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- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- Balboa Park
- Tijuana Beach
- Pacific Beach
- San Diego State University
- Torrey Pines State Beach
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- La Misión Beach
- Moonlight State Beach
- Las Olas Resort & Spa
- Belmont Park
- Sesame Place San Diego
- Liberty Station
- Oceanside Harbor





