House vacation rentals in Downtown San Diego

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Popular amenities for Downtown San Diego house rentals

House rentals with a pool

Guest favorite

Home in Mission Hills

4.94 out of 5 average rating, 202 reviews

Boutique home with view, heated pool, spa + cabana

Mar 31 – Apr 7

ﺩ.ﺇ2,209 per night
Guest favorite

Home in Serra Mesa

5.0 out of 5 average rating, 138 reviews

Midcentury Lux 4BR home with Pool, Spa & Cabana

Nov 1 – 8

ﺩ.ﺇ3,011 per night
Guest favorite

Home in San Diego

4.95 out of 5 average rating, 174 reviews

Casa Paradiso: Pool, Hot Tub, Outdoor Lounge!

Nov 29 – Dec 6

ﺩ.ﺇ3,992 per night
Guest favorite

Home in Point Loma Peninsula

4.93 out of 5 average rating, 119 reviews

Luxe Point Loma Oasis w/ Pool, Spa & Fire Pit

May 27 – Jun 3

ﺩ.ﺇ4,126 per night
Guest favorite

Home in San Diego

4.97 out of 5 average rating, 118 reviews

Luxe Home - Heated Pool - Steps to Best Dining

Jan 16 – 23

ﺩ.ﺇ3,597 per night
Guest favorite

Home in Bay Park

4.97 out of 5 average rating, 239 reviews

Resort Style Living with Pool, Spa, and Bay Views!

Oct 21 – 28

ﺩ.ﺇ3,097 per night
Superhost

Home in Paradise Hills

4.87 out of 5 average rating, 144 reviews

*Luxury Home* Salt Water Pool* Hot Tub* Fire Pit*

Nov 1 – 8

ﺩ.ﺇ1,794 per night
Guest favorite

Home in La Jolla

4.93 out of 5 average rating, 127 reviews

Ocean Front at La Jolla Shores

Apr 20 – 27

ﺩ.ﺇ3,118 per night

Weekly house rentals

Guest favorite

Home in La Mesa

4.99 out of 5 average rating, 120 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Jul 11 – 18

ﺩ.ﺇ457 per night
Guest favorite

Home in North Park

4.98 out of 5 average rating, 335 reviews

Modern 2BR Spanish Home on Balboa Park, 1M to Zoo

Dec 8 – 15

ﺩ.ﺇ1,184 per night
Guest favorite

Home in North Park

4.88 out of 5 average rating, 153 reviews

Private cottage walkable to restaurants and bars

Oct 11 – 18

ﺩ.ﺇ445 per night
Guest favorite

Home in San Diego

4.91 out of 5 average rating, 123 reviews

Point Loma Comfort w/ King Bed & Central Location

Sep 14 – 21

ﺩ.ﺇ518 per night
Guest favorite

Home in San Diego

4.97 out of 5 average rating, 132 reviews

Stunning Ocean Beach Gem - has everything!

Feb 8 – 15

ﺩ.ﺇ598 per night
Guest favorite

Home in San Diego

4.95 out of 5 average rating, 394 reviews

Admire Harbor Views from the Porch at a City Gem

Oct 14 – 21

ﺩ.ﺇ811 per night
Superhost

Home in San Diego

4.81 out of 5 average rating, 139 reviews

PRIVATE CASITA: BEACH, DOWNTOWN, ZOO W/IN 15 MIN!

Apr 20 – 27

ﺩ.ﺇ474 per night
Guest favorite

Home in South Park

4.92 out of 5 average rating, 135 reviews

Golden Hill Little House

Aug 16 – 23

ﺩ.ﺇ556 per night

Quick stats about house rentals in Downtown San Diego

  • Total rentals

    160 properties

  • Wifi availability

    160 properties include access to wifi

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Pet-friendly rentals

    50 properties allow pets

  • Family-friendly rentals

    100 properties are a good fit for families

  • Total number of reviews

    16K reviews

Destinations to explore