
Guesthouse vacation rentals in Downtown, San Antonio
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Top-rated guesthouse rentals in Downtown, San Antonio
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Popular amenities for Downtown, San Antonio guesthouse rentals
Family-friendly guest house rentals

Casa Lejana | Casita 1
We absolutely love Casa Lejana! The area is stunning and the room is very cozy. I love all of the trees and stars. Jenna and Brett are wonderful hosts. We will be back!

Close to Downtown -Casa Tierra Alta
We really liked this place. The outside area looked just like the pictures. We had coffee outside in the morning with our jammies on - very private. lol. At night we sat out and had a glass of wine by the fireplace. The downtown area was super noisy so it was nice to get back to a quiet neighbourhood. The inside was nice and homey with plenty of room. We stayed 5 nights and highly recommend this place!

Ideal for Couples. Great value. Close to Downtown
We stayed at Andrew's place for a concert this past week! Andrew provided such clear instructions to the home and even provided pictures! I love that they were so responsive & had great communication with my sister & I. The area felt safe to us. We felt so comfy because it's gated and our truck felt secure. The home was comfortable and cozy! My sister used the main bedroom and I used an inflatable mattress in the living room. It was great! The place was clean when we arrived. It was a cozy and nice stay for us while we stayed in San Antonio.

Sandra’s Cozy Cottage & Pool (Centrally Located!)
We loved our stay at this cozy little cottage. The location was amazing close to the highway. Sandra, the host, was very quick to respond to text and offer suggestions on places to go as well as where to eat nearby. We thoroughly enjoyed our stay. Visits from Searge, the pup, made our day! I would highly recommend this cottage. Felt like home.

Enchanting San Antonio Southtown guest cottage
This is a great place to get away. The house had perfect amenities. The linens were extremely comfortable and everything was clean. The dipping pool was fabulous and perfect size. The location is ideal for all the things around town. Steve and Cindi was very sweet and easy to talk too. The only thing I could say is that the ac unit did not blow very well. Besides that, everything was great.

Private Cottage Deco District/ Downtown area
We had an amazing stay. Very nice and peaceful location. Easy to get around from. Perfect little piece of heaven. Definitely a place I would recommend and stay at again. Hosts were amazing at check in and were helpful with recommendations.

Casa Alexander
Melody‘s place was very comfortable in a centrally located area. I appreciate it Melody‘s hospitality and I would like to return the next time I’m in the area. I highly recommend Melody‘s place to others!

Private Historic Charmer 3 Minute Walk From River
I loved my long weekend stay! It was perfectly located near downtown however just far enough away that you are not in the hustle and bustle. The river walk is just a couple blocks away and walks right into downtown, which I used several times. If you are going to San Antonio I would highly recommend Jen’s spot!
Guest house rentals with a patio

Flower Box Cottage
Had a great stay! The place was clean, cozy, and exactly as described. The host was super responsive and made everything easy. Definitely recommend and would stay again!

The Downtown Nest
I needed a quick reservation to recover after a two week work trip. Jessica was responsive and flexible setting up my reservation and then working with me to extend it a day. Her place was quiet, clean and comfy. It was a perfect fit for what I was looking for. I look forward to staying again.

Madriguera guest house
Very responsive and kind hosts. Clean and private. It was perfect!

The Little House
Thus was a super cute little place. Perfect for two looking for a peaceful stay. Check in was easy and everything was super clean. Hope we can stay here again in the future.

The Botanist's Bungalow
Absolutely delightful experience! Will was very kind and helpful and the accommodations were fantastic. I would love to stay here again. It’s a magical place, see for yourself!

4- A bedroom apartment near Airport and Downtown.
We had a fantastic stay! The unit was clean and equipped with all the extras you need and not have to pack and travel with. The location of place is as centrical as we wanted, close to all areas we were going to. All hosts were great, all communicated so promptly, and all directions were so clear and understanding. Unit was clean and cozy, AC worked great, no issues, neighborhood felt safe, very quiet area, minimal noise levels. Thank you!

The Casita
Such a cute spot! It was very clean and perfect for our family. Will definitely be back!

Beautiful guesthouse on a 2 acre gated property!
I really enjoyed my stay! Roxana was great and super responsive. She was very accommodating with an early check in. The property was really nice, I’m not sure the pictures did it justice! The entire property is fenced so it felt very private. The guesthouse was very clean and nicely laid out with plenty of space. The work space was great with a modern sit/stand desk. I had no problem being on a video call working in the space. The kitchen was stocked with everything I needed to prepare a small meal. The bed was comfortable and I definitely slept better there than I did at a recent hotel stay! Next time I am in San Antonio, I will definitely check the guest house for availability!
Guest house rentals with a washer and dryer

Southtown Carriage House w/ Tower of Americas View
Kelly was the perfect host - very easy to communicate with, clear instructions, helpful, and provided breakfast options (which was a nice touch). The apartment is in a carriage house on the alley behind their home with it's own dedicated parking. It's in a quiet neighborhood that has kind of funky vibe with lots of interesting restaurants just a few streets over. You can walk to downtown and the Alamo in about 20 minutes. The apartment was clean and welcoming and was lacking in nothing. The beds were comfortably firm. Would recommend staying here, especially if you intend to explore different neighborhoods, try unique restaurants, and walk a different section of the river walk.

Cozy Casita near Downtown & AFB Lackland
Jay & Magdalena were great hosts. Their casita was perfect for my little family. I saw on other reviews how they’re some really loud dogs next door, but to us they weren’t really that loud and we were able to sleep just fine. Jay and Magdalena were always very responsive whenever I had a question, and they also recommended us some great places to eat. I was very pleased on how clean the casita was. They provided everything you can need for a small trip, as a coffee lover I loved the Nespresso. My family and I arrived a little earlier than expected to San Antonio, and Jay and Magdalena were nice enough to let us check in earlier. I would definitely recommend Jay and Magdalena’s place to anyone planning on going to San Antonio.

Urban Family Friendly Getaway, Apt Unit2
The place was fine for what we paid for it initially. We were a bit concerned about the neighborhood but it was fine. The unit does need some work as the walls in the second bedroom are cracking and I am not positive the wall ac units would keep up with the Texas heat in summer. We had an issue that is clearly our fault my boys broke a lamp which of course is my responsibility but to value of the lamp in an extra bedroom was a little expensive. They did work with me and brought down the price of it, which I appreciate it.

SA City Tiny Farmhouse 🐴 Mins to Pearl ⭐️ Downtown
We had a fantastic stay at this cozy little house! It was the perfect home away from home—comfortable, clean, and thoughtfully furnished. The space felt warm and inviting, making it easy to relax after a long day. One of the highlights was its convenient location near Frost Bank Stadium, which made getting to and from the event incredibly easy. The neighborhood was quiet and felt safe, and the host was communicative and accommodating. We would definitely stay here again on our next trip to San Antonio!

Newly furnished 1Bedroom apartment near The Pearl
Donna was a fantastic host. She worked proactively with us to resolve an issue with the space that arose prior to our reservation and helped ensure that we were able to fully enjoy our stay. Would absolutely recommend her to anyone traveling to San Antonio.

Charming & Cozy 1BR, 1BA Downtown San Antonio
Eric & Carolyn’s place was perfect for a fun weekend at the NCAA Final four tournament. It was an easy walk to the Alamodome stadium with the Riverwalk just a little farther away. The bed was very comfortable, we loved that the tv had an AppleBox, and having laundry facilities in the unit was very convenient. We loved how it is tucked away behind the main house (standalone building) and was super quiet. Thank you for sharing your guesthouse with us!!

The Loft - Monte Vista
This home is located in a beautiful neighborhood, spacious, and well appointed. Eva was a great host! Very responsive and friendly at all times. She even left a little welcome note and treat for us upon arrival, that was just such a nice token of appreciation. The apt was also stocked with a variety of water, coffee, and tea.

Cozy-Chic Studio/Terrell Hills
Very nice place to stay for a weekend, lots of amenities and feels very home like, not far from base if you need a weekend off and not far from downtown or other attractions
Quick stats about guesthouse rentals in Downtown, San Antonio
Total rentals
40 properties
Nightly prices starting at
ﺩ.ﺇ147 before taxes and fees
Total number of reviews
4.6K reviews
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
40 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
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- San Antonio River Walk
- Alamodome
- Six Flags Fiesta Texas
- AT&T Center
- San Antonio Botanical Garden
- Guadalupe River State Park
- Schlitterbahn
- Blue Hole Regional Park
- Natural Bridge Caverns
- Morgan's Wonderland
- The Bandit Golf Club
- Government Canyon State Natural Area
- Canyon Springs Golf Club
- Natural Bridge Wildlife Ranch
- Brackenridge Park Golf Course
- Blanco State Park
- Jacob's Well Natural Area
- San Antonio Missions National Historical Park
- Tapatio Springs Hill Country Golf Course
- San Antonio Museum of Art
- Traders Village San Antonio
- The DoSeum
- Lakeside Golf Club
- McNay Art Museum