Vacation rentals in Defiance

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Top-rated vacation rentals in Defiance

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Chalet in Wright City

5 out of 5 average rating, 11 reviews

On The Rocks by Innsbrook Vacations!

DanielRating, 5 stars2 weeks ago

Innsbrook is one of the nicest private resorts in the area. This particular stay is very accommodating for larger families or maybe two small families looking for a lake vacation. the hot tub with the TV under the deck was perfect for us! The golf course is immaculate! Dane was a great host and very responsive!

Guest favorite

A view of the deck through large glass doors reveals two wicker chairs and a small table, surrounded by lush greenery. The ceiling is adorned with an antler chandelier, enhancing the connection to nature beyond.

Chalet in Innsbrook

4.95 out of 5 average rating, 178 reviews

Clean & Cozy Chalet in a Relaxing Wooded Scene.

AlexandraRating, 5 stars2 weeks ago

The Missing Peace Chalet was exactly what we needed for a last minute weekend getaway. It rained a lot, which we knew beforehand and picked this Chalet so we could enjoy listening to the waterfall and enjoy being surrounded by nature during rainfall. Truly a place where you feel like you can pause the craziness of life for a moment. We will definitely be back when it’s not a rainy weekend so we can enjoy all the extras that Laura and Russell offer when staying within Innsbrook. If I could give more than 5 stars, I would.

Guest favorite

Guesthouse in Gray Summit

5 out of 5 average rating, 5 reviews

Restoration Ranch Carriage Guest House

GaryRating, 5 stars4 weeks ago

Our stay at the carriage house surpassed our expectations. The grounds were so beautiful and pristine. The carriage house was so nice. The bed was so comfortable. Our dog, Ellie loved to hang out with the horses. She whined because she did not want to go in. Stephanie was such a gracious host. We will definitely return when we are in the area again.

Superhost

A wooden dock extends towards a calm lake, surrounded by lush greenery. Bright red chairs are positioned at the dock's edge, offering views of the water. The scene reflects a serene atmosphere with boats visible on the opposite shore.

Cottage in Innsbrook

4.88 out of 5 average rating, 100 reviews

Dock & Resort Perks: Quiet Lakefront Cottage

RRating, 5 stars4 months ago

We stayed for the Thanksgiving weekend and had a great time and even got some snow. The house is cozy and has a great view. We saw lots of wildlife from the warmth of the cabin. Would love to visit again in the warmer weather and enjoy the water sports. Everything was clean and the house was well stocked with everything you might need for a weekend in the woods.

Superhost

A staircase with white banisters and wooden steps leads to the upper level. The exposed antique brick wall provides historical character to the space. A woven area rug is positioned at the base of the stairs, complementing the warm wooden flooring.

Loft in Saint Charles

4.84 out of 5 average rating, 148 reviews

Main Street Historic Loft

DanielleRating, 5 stars1 month ago

This places was excellent. We enjoyed our stay. The place was cozy and comfortable, had what we needed. We were there on a Friday night…be warned it can get a little noisy outside so if that bothers you, then staying on a fairly busy street with lots of businesses probably isn’t for you. We weren’t bothered at all. Lots of great stores and restaurants on the same stretch of road. Definitely enjoyed our stay.

Top guest favorite

A sunlit screened-in porch features white wicker chairs with purple cushions positioned on polished wooden floors. Two hanging ferns provide greenery above, while a wooden swing adds a cozy seating area. Large windows allow for ample natural light and a view of the outside.

Home in Grafton

5 out of 5 average rating, 22 reviews

Stay In A Piece Of History

KimRating, 5 stars3 weeks ago

Caroline's place is amazing. The location is perfect. It is right on the main street and walkable to restaurants and shops. Seven of us stayed there for a girl's weekend, and we had plenty of space. We enjoyed the outdoor seating as well as the enclosed front porch area with the hanging swing.

Top guest favorite

A modern kitchen is equipped with stainless steel appliances, including a gas stove and dishwasher. Open shelving showcases dishes, while a well-organized layout features several drawers. Natural light enters through small windows above the sink, and sleek countertops complete the space.

Home in South Hampton

5 out of 5 average rating, 41 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

HowardRating, 5 stars1 week ago

The house is well laid out, clean, and in a nice neighborhood. The location is convenient, safe, and quiet. The owner was responsive and flexible. While there is a garage, we never used it as there was always on-street parking right in front of the house. Everyone in our party thought it was a great choice!

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What guests are saying

Luxury, Lakefront Chalet with Hottub and firepits

4.98 out of 5 average rating, 48 reviews2 months ago

Emily's place was fantastic. She responded right away to questions I had before, during and after our stay. She even forewarned us about the roads leading to the house with the cruddy weather. The house is beautiful, just like the photos. The kitchen is fully stocked and there are plenty of towels for showers and the hot tub. Everything was clean and well cared for. Layout is perfect for larger families and groups of people looking for a quiet place to relax and have fun.

Chalet in Innsbrook

What guests are saying

The Niederschulte House

4.96 out of 5 average rating, 46 reviews6 days ago

House was perfect for our visits to wineries and not that far to downtown St Louis to visit the Arch and botanical gardens, both of which were worth it. House had all amenities one could want - slow cooker, wine opener, colander, etc. Salt, pepper, oil, and some leftover ketchup and mustard, helped a lot for eating in. Restaurants are not very close, with the exception of 2 wineries, so we cooked. House was exceptionally clean. We had some soffit damage due to heavy windstorms, and it was fixed the day I called. (Very responsive!) Would highly recommend!

Home in Defiance

What guests are saying

Holly Hills hidden gem

5 out of 5 average rating, 4 reviews5 months ago

Tracey has created a lovely little haven. Her space exudes peace and comfort and provides all one could want for a short or longer stay. The park across the street was a great place to take my dog for walks. Grocery and other stores are nearby and the freeway is easily accessible. Tracey is a welcoming and thoughtful host.

Apartment in St. Louis

What guests are saying

Big Lake 'Livin A-Frame Chalet in Innsbrook Resort

4.82 out of 5 average rating, 116 reviews1 month ago

My family and I used this location for spring break and we had a blast. We were able to light a fire, use the boats, and jacuzzi. The place was very clean. Any issues (which was very few) were addressed imediately. Thank you so much for allowing us the opportunity to stay at your beautiful cabin

Chalet in Innsbrook

What guests are saying

Gorgeous Chalet with Cabin Feel (sleeps 10)

4.81 out of 5 average rating, 36 reviews6 months ago

As I celebrated my birthday, I sought a tranquil escape before the excitement of 6 Flags' Fear Fest. This Airbnb, nestled in a secluded yet accessible location, proved to be the perfect sanctuary. The opportunity to unwind by the firepit under the starry sky added a touch of magic to the experience. The host was incredibly responsive and helpful, even during a fire alarm incident that occurred while I was cooking. Their timely assistance allowed us to continue enjoying our stay without interruption. While the unfinished back porch was a minor inconvenience, it didn't impact our overall experience. The prime location and peaceful ambiance made it an ideal choice for a birthday getaway. The solitude and tranquility provided the perfect recharge before immersing ourselves in the thrilling adventures of 6 Flags. This Airbnb offers a serene escape for those seeking a quiet retreat. The host's responsiveness and commitment to guest satisfaction further enhance the overall experience.

Chalet in Innsbrook

What guests are saying

Lovely Couples Escape on Mississippi River!

4.98 out of 5 average rating, 52 reviews2 weeks ago

Our 4th stay and as always such a delight. We love the peacefulness of this getaway. The location is close enough to drive to St. Charles for a delicious dinner. Cozy is the best description for this property. Hosts are always in touch prior to arrival and instructions are clear. Well maintained and very clean. We will return again!

Loft in Saint Charles

What guests are saying

Luxury meets nature @ this Innsbrook stunning home

5 out of 5 average rating, 23 reviews6 months ago

We picked Charlton’s home for three couples’ annual birthday trip and everything from the start of booking to check-out and in between was perfect. Charlton was a super host and always responsive if we had a question. The home was very clean, super stocked, the furnishings were pleasingly tasteful and the setting was great! Over the years we have traveled to NC, TN, AR and MI for this annual trip and while we always enjoyed our rentals and surroundings, Charlton’s home is the first one that we all said we would go back and stay again! Thanks for a great stay!

Home in Innsbrook

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Popular amenities for Defiance vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Defiance's top sights

Montelle Winery18 locals recommend

Historic Daniel Boone Home15 locals recommend

Chandler Hill Vineyards15 locals recommend

Klondike Park14 locals recommend

Defiance Ridge Vineyards11 locals recommend

Noboleis Vineyards10 locals recommend

Other great vacation rentals in Defiance

Guest favorite

A lakeside home features a large deck with wooden railing, accessible by stairs. Natural stone firepit is surrounded by stones in the yard. Green grass and trees provide a serene backdrop. Water toys are visible nearby, emphasizing a family-friendly atmosphere.

Chalet in Innsbrook

4.96 out of 5 average rating, 77 reviews

Beautiful 5 Bedroom Lakefront Chalet with Beach

AmandaRating, 5 stars2 weeks ago

Matt’s place is stunning. The home is on a beautiful lake in Innsbrook. The views were gorgeous. The deck was beautiful. The living space is very well situated with a large Great Room. Fireplace, Extremely comfortable bedrooms. Large workable kitchen. We were seven people and had tons of space to just relax and enjoy. There were lots of games for us to play and we took advantage of that as the weather was not great. Matt was proactive and quick to respond. I appreciate the communication. I appreciated the cleanliness. I appreciated all the great recommendations.

Guest favorite

A fenced yard is featured, showcasing a blend of wooden panels in various tones. Flowering plants line the edge, with vibrant blooms among greenery. A putting green area is visible in the foreground, accompanied by a paved pathway leading to outdoor seating.

Home in St. Louis

4.89 out of 5 average rating, 207 reviews

Home away from Home St. Louis Cnty Ladue Schools

RaphaëlleRating, 5 stars3 weeks ago

Lisa was great! I needed a calm, peaceful and clean place for 2 weeks to recover from a surgery and her house was perfect. She was flexible with my arrival and departing time as I got updates from my surgeon and always worked it out with me, even last minute. There's a nice little park and neighborhood around and the house is very comfortable. Highly recommend!

Guest favorite

A spacious living area is featured with a large sectional couch and a round wooden coffee table. An electric fireplace is positioned below a wall-mounted TV displaying a beach scene. Kitchen and dining areas are visible in the background, showcasing modern appliances and a neutral color palette.

Apartment in Central West End

4.9 out of 5 average rating, 67 reviews

The Emerald House Near Wash U & Forest Park

LauraRating, 5 stars1 week ago

We loved our stay at Inayah and Bryson's place. We were in town visiting family and it felt like we were home. The place had everything we needed for our family of four and they checked in on us throughout the stay and promptly responded to our request to set up the outdoor furniture. We cannot wait to come back and stay again!

Guest favorite

A modern kitchen features crisp white cabinetry and stainless steel appliances. A large island with bar seating for four is illuminated by pendant lights. Natural light enters through a window by the dining area, enhancing the open and functional design.

Home in St. Louis

5 out of 5 average rating, 39 reviews

Bright Urban Comfort by JZ Vacation Rentals

JoshRating, 5 stars3 weeks ago

We really enjoyed our rental. The house was spacious, comfortable, and in a great location. Would definitely recommend!!

Superhost

A compact bathroom features a bathtub with a shower above, surrounded by neutral-toned tiles. A white vanity with a sink is positioned next to the bathtub. Light-colored products are arranged on the counter, and a decorative shower curtain adds a touch of color.

Private room in Hazelwood

4.73 out of 5 average rating, 11 reviews

A quick stay for the airport.

DaganRating, 5 stars2 months ago

Great place to stop for the airport

Guest favorite

A modern kitchen area features dark wooden cabinets and a granite countertop. An espresso machine is positioned beside a carousel of coffee pods. Stainless steel appliances are visible in the background, complemented by a vibrant painting of colorful umbrellas on the wall.

Home in O'Fallon

5 out of 5 average rating, 10 reviews

Quaint and Cozy Hamlet

SavannaRating, 5 stars3 weeks ago

My cousin was getting married and we needed a place to get ready. This house was PERFECT! Kevin was so incredibly nice letting us check in early and check out late to accommodate our wedding party. He went out of his way to make sure everything was exactly how we needed it. You don’t come by many people like that anymore! So blessed and thankful for Kevin and his generosity. Will definitely stay at this house again if I’m in the area!

An aerial view displays a large rectangular pool surrounded by a spacious patio area. Multiple lounge chairs are arranged around the pool, and shaded seating areas are highlighted with umbrellas. A designated grilling area is visible, adding to the outdoor amenities.

Cottage in Saint Clair

5 out of 5 average rating, 5 reviews

Guesthouse at Pinemark

BobbyRating, 5 stars6 months ago

Perfect for a wedding in town. Had plenty of room for multiple guests. Would stay here again

Guest favorite

A cozy living area is highlighted by a stone fireplace and two windows allowing natural light to enter. A comfortable blue sofa and a wooden coffee table complement the space, while a dark armchair is positioned for relaxation. The light-colored walls and floor enhance the inviting atmosphere.

Home in Grafton

4.98 out of 5 average rating, 93 reviews

Cozy Cottage off Main Street in Grafton

LeoRating, 5 stars1 month ago

The cottage was perfect for our weekend getaway! Linda was responsive, kind, and helpful. The space was clean and cozy. Highly recommend if you want a cute space close to the fun shops and restaurants in Grafton!

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Quick stats about vacation rentals in Defiance

Total rentals
10 properties
Nightly prices starting at
ﺩ.ﺇ257 before taxes and fees
Total number of reviews
340 reviews
Wifi availability
10 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Local attractions
Defiance Roadhouse, Defiance Ridge Vineyards, and Good News Brewing Company Defiance

Vacation rentals in Defiance

Top-rated vacation rentals in Defiance

Luxury, Lakefront Chalet with Hottub and firepits

Dogwood Treehouse (Innsbrook)

The Niederschulte House

Caper on Kings

Holly Hills hidden gem

Big Lake 'Livin A-Frame Chalet in Innsbrook Resort

Entire House in House Springs

Cozy Lake Hideaway at Innsbrook

American Spirit

Gorgeous Chalet with Cabin Feel (sleeps 10)

Lovely Couples Escape on Mississippi River!

Luxury meets nature @ this Innsbrook stunning home

Vacation rentals for every style

Popular amenities for Defiance vacation rentals

Stay near Defiance's top sights

Other great vacation rentals in Defiance

Quick stats about vacation rentals in Defiance

Total rentals

Nightly prices starting at

Total number of reviews

Wifi availability

Popular amenities

Local attractions

Destinations to explore