
Family-friendly vacation rentals in Clayton
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Clayton

Total vacation rentals
Explore 20 vacation rentals in Clayton

Nightly prices starting at
Clayton vacation rentals start at ﺩ.ﺇ 294 per night before taxes and fees

Verified guest reviews
Over 1,120 verified reviews to help you choose

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Clayton vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Clayton rentals

4.7 Average rating
Clayton stays receive an average rating of 4.7 out of 5 from guests
Top-rated family-friendly rentals in Clayton
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Large U. City Apt 4 BR, 2 Bath, Pool, near Wash U.
Deb and I welcome you to our newly renovated charming U City first floor apartment - your home base to explore the best of St. Louis neighborhoods. Close to Wash U & Metro link. Minutes from Forest Park, Zoo, Loop, and Clayton - just 12 min to downtown. Choose from dozens of nearby restaurants or stay home and cook in the spacious kitchen. Lounge by the large pool open June through September. In unit washer/dryer. Park with playground and public tennis/pickleball courts across the street.
Indoor spacesKitchenBathroom

Dogtown Century home near Forest Park & Maplewood
Our historic home has lots of natural light and high ceilings. The two bedrooms are furnished with comfy queen beds. The sunroom also doubles as a third sleeping room. Enjoy a morning cup of coffee on the large front porch, or yard games and bbq in the fenced back yard. The updated kitchen comes fully equipped with everything you need to help you feel right at home. Minutes from Forest Park, BJC and SSM hospitals, universities, downtown, many great restaurants and shops. Furry friends welcome!
Indoor spacesFamilyWalkability

3-bdrm apt near Pageant, Wash U, Forest Park, Loop
Three bdrm, top floor apt. with private entrance in our home. Roomy, comfy, well-furnished with everything you need. Walk to Pageant, Delmar Hall, WashU, Blueberry Hill, Salt&Smoke, MagicMiniGolf. CVS, grocery, restaurants and shops on the Delmar Loop. Or stroll our leafy streets to Forest Park, built 1904 for a World’s Fair, now a first-class museum, zoo, golf course, boat rental. Easy access via metro train or Uber/Lyft to airport, baseball, hockey, live music clubs, City Museum, the Arch.
Indoor spacesKitchenCondition

Tranquil three-bedroom home in central St. Louis
Welcome to Spa 7748! Relax and enjoy the quiet, tranquil space we have to offer you. Three bedrooms, two full baths, laundry room, work out area, media/office area, fully equipped chef’s kitchen, two fireplaces, covered patio, outdoor fire pit, driveway parking, and street parking. Centrally located in University City, which is just minutes from the downtown Clayton business/entertainment district, Washington University, Fontbonne University Downtown STL, Central West End, The Grove, Dogtown.
FamilyKitchenAmenities

Cozy Cottage in a Quiet City Neighborhood!
Please inquire for longer stay rates. This 650sq.ft quaint cottage has EVERYTHING! Centrally located this sought after historical neighborhood, DOGTOWN!, is just minutes from Forest Park and a short drive to all of STL's BEST ATTRACTIONS! This charmer has all the amenities you could hope for @ your HOME away from home! 2 Bedrooms with a Queen Bed in each, 3 Smart TV's, a backyard patio, KEYLESS Self Entry, fully equppied kitchen with SS appliances, MAIN FLOOR LAUNDRY and fully UPDATED BATH!
KitchenIndoor spacesBackyard

Charming Cottage Near Forest Park in Quiet Area
Welcome to our home! It is a cozy brick bungalow from 1929. It is a quiet neighborhood. Partially fenced backyard. We're located close to historic Route 66, coffee shops, shops, restaurants. 15 minute drive from Gateway Arch National Park, Busch Stadium, Forest Park, Enterprise Center, Washington University, St. Louis University, Zoo, Art Museum, and Botanical Gardens. Smoking is not allowed inside or outside. Any smoke odor will result in a $150 fine. Noise monitoring device on property.
FamilyKitchenOutdoor spaces

1 BR Loft Near Central West End, Walk to BJC
Welcome to loft luxury, walking distance to BJC, nightlife, metro station, & Whole Foods! This space includes garage parking, in-unit W/D, and everything to stay a night or a month! Other great features: - High ceilings & huge windows - Pullout couch - 55" TV - Workspace w/ fast wireless internet - Fully-equipped kitchen - Queen memory foam bed *Please note, this loft's bedroom walls don't extend to the ceiling & there is no door. Please check photos to ensure the space meets your needs!
Indoor spacesKitchenCleanliness

A Modern Oasis in U. City/Clayton
Welcome to our apartment in the University City and Clayton area on Delmar Blvd near the Delmar Loop. We own this 4 unit apartment building with garage space and free off street parking. We have renovated this 3 bedroom, 1 bath spacious, airy and bright space for you. Enjoy the benefits and skip the hassle to stay in this cozy unit with modern furniture and clean accommodations in this safe neighborhood. Sleeps 6 but book with 2 other listings in this building for up to 18 guests total.
KitchenFamilyWalkability

Great Fam Friendly Home w/ Lrg Deck & Yard
**FAMILY FRIENDLY** (See details for the items avail for families) This 2 bedroom home has everything you need for a relaxing trip! Fully updated with stylish and comfortable furniture and decor. Fully equipped kitchen and an amazing backyard/deck. Quiet street by one of the best Mexican restaurants in St. Louis - Hacienda - (can walk 2 min there) Close to everything! 13 minutes to the St. Louis Zoo 10 minutes to The Magic House 15 minutes to Busch Stadium & Union Station
KitchenIndoor spacesLayout

Cozy, Family Friendly at Zoo & Forest Park
This home is centrally located to all Saint Louis attractions and half a mile walk from the Zoo and steps away from historic Dogtown! The 3bed/2 full bath home is equipped with mini crib and mattress, rocking chair, two strollers, child books, family games, toys, and is baby proofed throughout the home w/child gates. Enjoy the playground, huge sandbox, gas grill, pool table & foosball table. Eloquently styled for your family, friend meet-up or work retreat.
Indoor spacesKitchenNearby

Weaver Guest House
This charming, light-filled cottage feels like its own private hideaway, yet it's close to everything St. Louis has to offer. Tucked between trees in a quiet Maplewood neighborhood, it's a 15-minute walk to the MetroLink and a 10-minute drive to Washington University, Webster University, Fontbonne University, Forest Park, and Clayton. Business travelers and families alike will appreciate the washer/dryer, fast WIFI and cable TV.
KitchenFamilyValue

Large, Woodsy, Warm and Inviting | Cozy 2BR Apt
Tucked in a quiet neighborhood near the Delmar Loop, this 2-bedroom, 1-bath apartment offers a stylish and comfortable retreat. Enjoy a fully stocked kitchen with stainless steel appliances, a record player, and a 55” Google TV for streaming. Step outside to a shared patio with seating, outdoor dining, and a kids’ playground. Additional amenities include a dedicated workspace and in-house washer/dryer.
FamilyIndoor spacesBiking
Popular amenities for Clayton family-friendly rentals
Family-friendly home rentals with a hot tub

Luxury Getaway | Hot Tub, Pool Table & Garage
Indoor spacesKitchenLayout

Hot Tub * New Renovated * Massage Shower * Yard
FamilyIndoor spacesParks

Lux! Hot Tub. Game Room. Sauna. Fitness. Fire Pit.
FamilyIndoor spacesHospitality

*NEW HotTub* The Jewel on 5th-2br2b-near Main
FamilyKitchenTV

Spacious home with entertainment room and hot tub
KitchenIndoor spacesCheckout

Private Oasis w/hot tub
KitchenIndoor spacesParking

Luxurious, spa-like retreat steps from Main St.
KitchenIndoor spacesTV

Lodge at Pine Lake - Hot tub, lake, pets welcome
FamilyKitchenWifi
Family- and pet-friendly home rentals

Dogtown: The Place to Be near the Zoo, Wash U, BJC
FamilyKitchenView

King Suite • Art District • Fiber WiFi • Laundry
Indoor spacesKitchenSleep quality

The Little House.
KitchenFamilyBathroom

New: Cozy Cottage Near The Hill
FamilyIndoor spacesBackyard

Stylish Retreat | Cozy Apt. near Top Attractions!
KitchenIndoor spacesWifi

Paw-some Retreat: Fenced Yard, Near Hospitals, W/D
KitchenIndoor spacesValue

Dogtown:Yard/Barnes/SLU/WashU/Arch/Zoo/Forest Park
Indoor spacesFamilyDecor

Free for pets. No fees. Private. Keyless entry.
Indoor spacesFamilyParking
Family-friendly home rentals with a pool

Private indoor pool & sauna
Indoor spacesFamilyAccuracy

Blair's Pool House - Creve Couer Hot Tub Game Room
FamilyIndoor spacesBathroom

Arch View Luxury: Hottub-Pool-Sauna-Wine &Brkfst
KitchenIndoor spacesAir conditioning

Holly Hills hidden gem
Indoor spacesComfortCheckout

Spacious Home - Heated Pool Open - Amenity Packed
FamilyKitchenDecor

Roomy Oasis with hot tub on the Hill!
FamilyIndoor spacesComfort

Secluded Property w Pool and Hot Tub
KitchenIndoor spacesPool

Tower Grove Oasis #1 + King Bed + Queen Bed+ Patio
FamilyIndoor spacesCleanliness
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- Busch Stadium
- Central West End
- Six Flags St. Louis
- Saint Louis Zoo
- The Dome at America's Center
- Enterprise Center
- St. Louis Aquarium at Union Station
- Gateway Arch
- City Museum
- Missouri Botanical Garden
- Washington University in St Louis
- Forest Park
- Hidden Valley Ski Resort
- Meramec Caverns
- Saint Louis University
- The Pageant
- Castlewood State Park
- Gateway Arch National Park
- Saint Louis Science Center
- Soulard Farmers Market
- Westport Plaza
- Missouri History Museum
- Fabulous Fox
- Laumeier Sculpture Park





