Boutique hotel vacation rentals in Central Illinois

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Central Illinois

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Boutique hotel in Washington

4.98 out of 5 average rating, 102 reviews

River Sirens Hotel Deluxe Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.

Jan 6 – 13

ﺩ.ﺇ611 per night

Guest favorite

Hotel room in Hermann

4.86 out of 5 average rating, 63 reviews

Hermann Crown's Katy Trail Suite, Amenities Galore

Welcome to the Hermann Crown Suites Katy Trail Suite. This Queen Bedroom Suite with Private Bath Celebrates the Katy Trail with Vintage Railroad and Bicycling Decor. Outstanding Amenities Include: Free Breakfast, Free Drink Coupons to the Midwest Renowned Onsite Hermann1837 Cellar Bar, and $25 Shuttle Service Daily to the Wineries. Walking Distance to Restaurants. Elevator Access. Free Live Bands on Weekends and 7 days a week May through October. Electric Vehicle Charging Onsite!

Jul 6 – 13

ﺩ.ﺇ663 per night

Guest favorite

Boutique hotel in Hannibal

4.95 out of 5 average rating, 100 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Jan 10 – 17

ﺩ.ﺇ428 per night

Superhost

Boutique hotel in Grafton

4.9 out of 5 average rating, 49 reviews

Rafton Inn Vacation Cottage 73

These charming, newly renovated, light-filled cottages feels like its own private hideaway, yet it's close to everything Grafton has to offer. Settled behind our charming three bedroom private main house (also ready for booking). It's walking distance to the river, shopping, restaurants, wineries, zip line, Sky Tour, short drive to Raging River's water park and State Park. Families, Friends and Business travelers alike will appreciate the view, fast wifi, cable TV, washer/dryer.

Sep 4 – 11

ﺩ.ﺇ575 per night

Guest favorite

Boutique hotel in Pacific

4.9 out of 5 average rating, 39 reviews

Pilot four. room for two with pool

Bookings are allowed 6 months in advance. Private queen room in a new boutique hotel offers a cozy queen bed, half bath in suite. There are shower rooms located on the 2nd floor near this room. There is a comfy common area outside the room, as well as additional shared spaces on the main floor. There is a large community kitchen for use and plenty of dining and activity spaces. Please only 1 med to lg dog for this space. if traveling with smaller pets please inquire.

Aug 27 – Sep 3

ﺩ.ﺇ434 per night

Guest favorite

Boutique hotel in Hermann

4.97 out of 5 average rating, 120 reviews

The Artists Suites, Claude Monet Suite

One of four rooms available at the Artist Suites, The Monet Room is carefully crafted to represent the unmatched talent of Claude Monet. You will not be disappointed with your stay at this creative property, which also hosts an art gallery and studio next door. All 4 rooms are located on the second floor, sharing a hallway in our beautiful brick building, constructed in the late 1800’s.

Jan 5 – 12

ﺩ.ﺇ603 per night

Guest favorite

Boutique hotel in Terre Haute

5.0 out of 5 average rating, 8 reviews

The Sunrise Room at The Sycamore Farmhouse

At the Sycamore Farmhouse, you'll find a comfortable place to rest your head. Whether celebrating a wedding with us, visiting friends or family, or simply passing through, enjoy the historic beauty and hospitality that The Sycamore Farm has to offer. Enjoy coffee and breakfast, which is included in your room rental, at Maggie & Moe's Coffee located on the first floor of the farmhouse.

Aug 6 – 13

ﺩ.ﺇ362 per night

Guest favorite

Boutique hotel in Saint Louis

4.89 out of 5 average rating, 829 reviews

King Redwood Bedroom at BnB in CWE!

This is the largest of the rooms we have at our CWE BnB - an historic house in St. Louis' premier neighborhood. It has one King sized bed, a pullout sleeper sofa, two back-to-back 45" 4K Smart TVs with Rokus, and bathroom and kitchen space shared with guests of other rooms on this floor. Within a short walk of the basilica and many bars and restaurants in the CWE!

Sep 16 – 23

ﺩ.ﺇ312 per night

Superhost

Boutique hotel in Washington

4.86 out of 5 average rating, 132 reviews

430 West Front: Balcony Riverfront View

This room is located on the second floor over our quaint wine bar with a private balcony overlooking the Missouri River. Enjoy a cup of coffee or glass of wine from our wine bar on your private balcony. Just steps from our Historic downtown riverfront community with plenty of bars, restaurants, and charming shops to explore.

Feb 12 – 19

ﺩ.ﺇ485 per night

Superhost

Boutique hotel in Louisiana

5.0 out of 5 average rating, 4 reviews

The Eagles Nest Inn

The Eagles Nest Inn is a family-run Inn tucked away in historic downtown Louisiana, Missouri. Our lovingly restored historic building features comfortable and inviting guest rooms, each with its own unique character. You'll experience our quaint town like a local, thanks to our helpful tips and recommendations.

Dec 14 – 21

ﺩ.ﺇ471 per night

Guest favorite

Boutique hotel in Breese

4.93 out of 5 average rating, 30 reviews

Breese Inn - Executive Deluxe Room-No added fees!

Tranquil and modest, the Executive Deluxe Room is filled with everything you need for a quiet respite. This charming second floor hideaway features everything: serene décor, a comfortable queen bed, a luxurious jacuzzi tub, Keurig coffee maker and a writing desk for organizing notes or paperwork.

Aug 17 – 24

ﺩ.ﺇ347 per night

Superhost

Boutique hotel in Grafton

4.89 out of 5 average rating, 18 reviews

River View Guest House, The Eagle's Nest

River View Guest Houses have magnificent views of the Mississippi and Illinois rivers. The large yards are outfitted with fire pits and picinic tables. Large covered decks or patios are perfect for dining alfresco! Both units are within walking distance to most attractions.

Oct 29 – Nov 5

ﺩ.ﺇ744 per night