Hotel vacation rentals in Downtown / Union Square

4.92 out of 5 average rating, 26 reviews

A spacious room features a large bed with a dark headboard, complemented by decorative pillows. A comfortable seating area includes a sofa and a small table. Natural light filters through large windows adorned with sheer curtains, enhancing the calming ambiance.

Resort in Union Square

Chic King Suite at Wyndham Donatello in SF

Escape to a tranquil retreat in the heart of San Francisco's Union Square neighborhood. Discover serenity and sophistication at our elegant resort, where you can unwind and rejuvenate amidst the bustling city. Immerse yourself in the vibrant energy of San Francisco, from its iconic landmarks to its charming neighborhoods. Indulge in the comfort and style of our luxury accommodations. Relax and recharge in our thoughtfully designed space, complete with modern amenities and a soothing ambiance.

Hotel room in South of Market

A well-lit room features a spacious bed with gray linens. A small table and chairs are positioned next to a window. A flat-screen TV is mounted on the wall opposite the bed, with a white shelving unit nearby. The room offers a minimalist design.

4.8 out of 5 average rating, 49 reviews

SoMa 9 Residences Room 7 Shared Bath

SOMA (short for South of Market St) is top of the list for where to stay in San Francisco for the first time. SOMA 9 Residences is located in the Heart of SF SOMA District, were you'll find everything from shopping to fine dining, plus landmarks such as Yerba Buena, Moscone convention center, SF MOMA, and steps away to Giants Ballpark. The proximity to Market St. makes SOMA one of the most accessible areas of the city. There's buses and rail lines (called BART) on just about every block.

New place to stay

Sophisticated Stay | Cable Cars Tours. Gym

Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

A spacious room is highlighted by a large bed with a white duvet and decorative pillows. A modern artwork featuring a woman and butterflies is mounted above the bed. Two bedside tables flank the bed, and a window with sheer curtains allows natural light to enter.

4.86 out of 5 average rating, 85 reviews

Book-filled Writer’s Alcove in the lobby

Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

4.7 out of 5 average rating, 53 reviews

An elegant hotel exterior is displayed at night, featuring a well-lit facade with blue accents. Surrounding trees are lit up, and the vibrant street scene includes moving cars. The building's top is adorned with an American flag, contributing to the lively urban atmosphere.

Hotel room in Nob Hill

Art-centric stay with views from atop Nob Hill

Power down and recharge in our stylish, minimalist accommodations—an ideal retreat for modern mavericks and mavens seeking a break from the city’s energy. Enjoy clean lines, custom-designed furniture, and thoughtfully simple design for ultimate comfort. Our compact, interior-facing rooms span 205–220 square feet and feature a Queen or King bed. Each space is efficiently equipped with a 49” HD television, HDMI and USB ports, USB outlets, and a mini-fridge for your convenience.

A spacious guest room features a king bed with crisp white linens against a warm wood headboard. A window with light-filtering shades provides natural light, while modern fixtures and a wooden shelving unit offer functionality and style.

4.77 out of 5 average rating, 31 reviews

Fun Respite | Happy Hour. Game Room. Pet Friendly.

Axiom Hotel, a 4-star establishment in San Francisco's city center, is an ideal accommodation for those looking for a fun hotel to stay in during their trip to SF. It features a fitness center and a game room. Guests can also venture out to see prime attractions nearby, like Moscone Center and the Ferry Building. ✔ Fitness center ✔ Robot-delivered room service ✔ Pet-friendly ✔ Arcade games ✔ Cafe on-site ✔ Breakfast, lunch, dinner, boba and a full bar

Hotel room in Pacific Heights

A spacious bedroom features a soft-colored quilted bed with plush pillows. Natural light floods in through large windows dressed in sheer curtains. A small table with white chairs is positioned near the window, enhancing the room's airy feel.

4.8 out of 5 average rating, 65 reviews

Monroe Studio 303

The Monroe Residence Club is a residential hotel located centrally in the heart of San Francisco with public transportation at our doorstep and local shops and businesses nearby. It is conveniently located just a block from Whole Foods, blocks from a the iconic Lafayette Park, within walking distance of several hospitals and more! The Monroe offers 24-hour front desk security, breakfast and dinner on-site, as well as common areas for congregating.

Top guest favorite

A spacious living area is highlighted by a light-colored sofa, accompanied by a patterned throw and decorative cushions. Artwork adorns the walls, and a dining area with modern chairs is visible in the background, leading to the kitchenette and staircase.

Casa particular in San Francisco

4.95 out of 5 average rating, 125 reviews

Boutique large studio in NoPa San Francisco

Self-contained large studio in San Francisco with kitchenette. Located in San Francisco's NoPa area which provides some of the best restaurants and bars in the city as well as close access to the outside spaces of the Panhandle and Golden Gate Park. The studio is located on a quiet street which is a 5 minute walk from the NoPa restaurants and Bi-Rite on Divisadero, 7 mins walk from Alamo Square and 15 mins walk from Golden Gate Park

A cozy kitchen area features a small round table set for two, adorned with a vibrant tablecloth. Bright flowers are arranged in a vase on the table. Cabinets in soft green and a white gas stove are visible, alongside a window showcasing colorful buildings outside.

Hotel room in Marina

4.65 out of 5 average rating, 231 reviews

Queen Street Suite, Dog+, Reserved Parking

This is a street facing room with one queen bed, a sofa; and a full kitchen. We are a small family run Motel in the Marina district, close to Cow Hollow and Pacific Heights. You’ll love this motel because of the walk-able neighborhood, the roomy kitchen, cozy European feel and the free off-street parking. This is a dog friendly room. (with an extra charge of $25 per dog, per night) Sorry, no cats are permitted.

A well-appointed sitting area is created with two elegant armchairs and two striped chairs surrounding a glass-topped coffee table. A decorative fireplace serves as a focal point, complemented by soft lighting from the lamps on either side.

5 out of 5 average rating, 11 reviews

San Francisco Suites Studio lll on Nob Hill

Unwind in this quiet and cozy parlor suite, designed for ultimate relaxation. Tucked away from street noise, you'll enjoy a peaceful atmosphere perfect for a restful getaway. The open and airy floor plan features a comfortable space, and you can indulge in the whirlpool Jacuzzi bathtub/shower combination. Prepare your favorite meals in the full kitchen, making your stay even more convenient and enjoyable.

4.88 out of 5 average rating, 84 reviews

The exterior view of The Marker showcases its Beaux-Arts architecture with elegant detailing. Multiple stories feature large windows, illuminated at dusk, creating a welcoming ambiance. The building is framed by trees and streetlights, set against a softly lit sky.

Hotel room in Tenderloin

Union Square Stay | On Site Restaurant & Bar

The Marker brings sophistication and style to San Francisco like no other. Set in one of the most vibrant and captivating cities in the world, the Beaux-arts style hotel invites you to feel inspired and right at home. Just steps from Union Square, welcome to The Marker, where modern elegance effortlessly blends to classic Bay Area charm. Winner of the Conde Nast Traveler Readers Choice Awards 2019-2022.

A spacious hotel room features a comfortable King bed and a sleek sofa with accent pillows. Natural light fills the room through large windows adorned with light drapes, while a workspace and television are situated nearby, creating a functional and well-appointed area.