Apartment vacation rentals in South Euclid

Cle Rocks-Little Italy! W Massage chair/Hot tub #2

Fall in love with this charming, newly updated 2-bedroom, 1-bath upper unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!

Location · Family · Nearby

Little Italy 3, close to Cleveland Clinic, CWRU

Enjoy a uniquely styled experience at this boho-chic apartment in the heart of Little Italy. Exposed brick walls, hardwood floors, and wooden furnishings combine to give this apartment a boho-chic aesthetic. Enjoy dinner in the cozy kitchen and watch TV while relaxing on the comfortable sofa. One flight of stairs is leading up to the second floor (17 steps)The unit is on a quiet side street in walking distance to the heart of Little Italy (restaurants,cafes, shops).Free parking on premises(1car)

Value · Location · Kitchen

2nd Floor Semi Private Apartment Cleveland Heights

Near East Side. 2nd floor apt. private bed rooms, bath, living room and kitchen*, semi-private entrance. Off-street parking, grill & laundry facilities in basement. Close to Case, Cleveland Clinic, Univ Hospital, many museums. Great public trans access. Great for couples, solo or business travelers, small families, motorcyclists, bicyclists, anyone who likes cats. LGBTQ, all ethnicities welcome. Min 4 night stay; requests only within 30 days. (*fridge, microwave, air-fryer, rice cooker).

Location · Value · Cleanliness

Modern & Peaceful Loft | Private Entrance

You’ll experience comfort and privacy in this renovated Shaker Heights studio, just minutes from Cleveland Clinic. Professionally designed for peaceful stays with a private entrance, $5k+ countertops, fridge & freezer, microwave, $1k+ queen bed, soft close cabinets, firm mattress, etc. Enjoy fast Wi-Fi, secure self check-in, perfect for medical visits, work trips. Located in a safe/historic neighborhood. Apartment is located on 3rd floor of a Tudor house, some stairs are required to access.

Value · Location · Laundry

Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic

Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!

Value · Location · Parking

Private 2 Level Apartment with Hot Tub in Tremont

Welcome to this remodeled, charming 1 bed 1 bath in the heart of Tremont. This special place is just a minutes walk from all the bars, restaurants, cafes, parks, and vintage stores. Enjoy two floors of living space and a spacious deck on the second floor that is perfect for relaxing with your favorite drink or entertaining friends!! The unit has a private entrance with an open kitchen, LR, BR with a closet and a small workspace; WD. With a private brand new hot tub with plenty of space for 4!

Location · Value · Heating

Gem Stone Villa--12 minutes to CCF,CWRU,UH

The Gem Stone Villa features a 2 Bdrm/1 Bath apt located in the vibrant city of South Euclid that is 12 min to CWRU/Cleveland Clinic/Univ. Hospitals. This listing is for the down unit in a villa style duplex home composed of two separate apt suites. This apartment is fully furnished with a blend of modern and traditional décor featuring glamorous wood floors in a full living room with fireplace, dining room, updated kitchen and enclosed porch. Inquire about our weekly/monthly stay discounts!

Location · Wifi · Comfort

2BR Near Cleveland Clinic | Garage & Patio

Make yourself at home in this bright second-floor apartment in charming Cleveland Heights, just minutes from Cleveland Clinic, Case Western Reserve University, University Circle, and Little Italy. Relax in two comfortable bedrooms, prepare meals in the fully equipped kitchen, unwind on the private screened patio, and enjoy the convenience of private garage parking, high-speed Wi-Fi, and a dedicated workspace. Ideal for families, medical visitors, business travelers, and extended stays.

Location · Value · Sleep quality

Blake Zax Stylish Flat In Historic 1920s Building

Wifi is 1 GIG speed -Designer Done space. An inviting living room, A Bedroom with an area to get work with a desk and chair and a king size bed, luxury bedding and blackout drapes. Kitchen w/full size fridge, Gas Stove, microwave, Keurig coffee maker, toaster. Dining table w/ seating for 2. 11 minute drive to Cleveland Clinic, University Hospitals & Case Western Reserve. Cleveland Art Museum, Cleveland Botanical Gardens, and downtown Cleveland. 2nd floor walk up.

Location · Value · Decor

Stylish 2BR Retreat | Minutes to Beach & Downtown

Welcome to this beautifully renovated lower-level unit, designed for comfort and relaxation. Enjoy a warm, thoughtfully curated space from the moment you arrive, with inviting interiors that make it easy to settle in and feel at home🏠 Just minutes from Downtown, with a scenic Lake Erie park at the end of the street, perfect for picnics and sunsets. Whether for a quick getaway or a longer stay, this home is ready to welcome you with ease and convenience✨

Family · Location · Check-in

Gallery House | Near Clinic + Museums

🎨 Artist-curated apartment • Sleeps 4 🛋 Decorated w/ works by local artists (for sale!) 🛏 2 bedrooms • 1 bathroom ✨ Modern & bright 📍 Minutes to Cleveland Clinic, UH & CWRU 🎶 Walk to dining, bars, shopping & Cleveland Orchestra 📺 Smart TV w/ streaming apps 🚗 1 mid-sized off-street parking spot + free street parking Stay in style and surround yourself with Cleveland’s creative spirit — a one-of-a-kind apartment curated by local artist Dawn Tekler.

Location · Value · Check-in

The Maproom Room | 10 Mins to Cleveland Clinic, UH

🗺️ Map-themed studio • Sleeps 2 ✨ Fully renovated • Clean + modern ☕ Kitchenette • Coffee maker • Microwave & Instapot 📺 Smart Roku TV + streaming apps 🚗 Off-street parking for midsize cars (1 spot) 📍 10 min to Cleveland Clinic + University Circle Modern comfort meets world travel charm in this map-inspired studio apartment — thoughtfully designed and ideally located near Cleveland’s best cultural attractions.

Value · Location · Layout