
Places to stay near Case Western Reserve University
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Top-rated vacation rentals near Case Western Reserve University
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In the heart of Little Italy! Free Parking! 3BR-UP
Enjoy your stay at this centrally located - upper unit- in a two-family home in Little Italy. Apartment is complete with a well-equipped kitchen. The living room includes comfortable seating for 6, a smart TV, 3 poufs & coffee table - so that ALL may rest their feet from a long day, modern furnishings and a washer/dryer/linen closet. Each bedroom includes USB plugs in the lamps, alarm clocks with sound machines, blackout curtains, ceiling fans, Smart TVs, "ultra-quiet" ACs, desk, chair & mirror.

Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled experience at this boho-chic apartment in the heart of Little Italy. Exposed brick walls, hardwood floors, and wooden furnishings combine to give this apartment a boho-chic aesthetic. Enjoy dinner in the cozy kitchen and watch TV while relaxing on the comfortable sofa. One flight of stairs is leading up to the second floor (17 steps)The unit is on a quiet side street in walking distance to the heart of Little Italy (restaurants,cafes, shops).Free parking on premises(1car)

The Farmhouse - 1 Bdrm Apt in a Great Location
Welcome to this 2nd flr 1 bd/1 ba private apartment in a charming 1880s farmhouse located in a friendly walkable neighborhood. Full kitchen with all you need to make your own meals, washer/dryer and separate office inside the unit. Free off-street parking. You are only: 5 min walk to Starbucks, a variety of restaurants, bars, shops, trails 5-10 min drive to Cleveland Clinic, University Hospitals, Case Western, museums, parks, Little Italy and more 15 min drive to major attractions and Lake Erie

Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

New! “Modernistic Retreat”
Elevate your stay in this bright, elegant and spacious 3rd floor apartment that offers the perfect blend of tranquility and urban convenience. Less than 10 minutes from Cleveland Clinic, 8 min from Case Western University, 17 min from Rock and Roll Hall of Fame, 18 min from Cleveland Browns Stadium, 20 min from Downtown, 28 min from Cleveland Airport and 45 min from Blossom Music Venue. Moments from charmed local neighborhoods such as Coventry, Little Italy, Cedar Fairmont and Lee Rd.

Mid-Century Modern Retreat in Little Italy
Nestled in the vibrant yet peaceful and safe Little Italy neighborhood of Cleveland, this newly remodeled Mid-Century Modern style 2bed/1bath Lower unit is within walking distance to the best Cleveland has to offer. Enjoy a stroll to Case Western Reserve University, University Circle, the Cleveland Museum of Art, Cleveland Botanical Garden, and more. Discover local shops, bakeries, and renowned restaurants that give Little Italy its charm. The RTA redline station is a five minute walk.

Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #6
Fully furnished luxury apartment that has been completely renovated combining old-time 19th century charm with modern amenities. Just move in with your suitcase! Within walking distance to the Cleveland Clinic Campus (5 min walk from main hospital). It’s also near University Hospitals, CWRU, Great University Circle, Downtown Cleveland, and Little Italy. This location is perfect for those receiving medical treatments and their families, doctors on rotation, travel nurses, and interns.

Rare Cleveland Apt: Little Italy! W/Sauna&Hot tub!
Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated in the heart of Little Italy, walking distance from University Circle, UH Hospital, Cleveland Museum of Art, Botanical Garden, Public Transportation and much more. Apartment is complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation/business rental delivers all the essentials so you can spend more time relaxing and exploring.

Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

Steps to Cleveland Clinic - Sleeps 3
Discover a beautifully remodeled 1-bedroom retreat in a Victorian home built in the 1800s, just a short walk from the Cleveland Clinic. This inviting space comfortably sleeps 3, featuring a cozy bedroom, a pull-out couch, a fully equipped kitchen, private parking, and modern amenities like keyless entry and a temperature-controlled system. Perfect for work, relaxation, or extended stays, this charming unit offers the ideal blend of comfort and convenience.

Peaceful Mansion Studio | Steps from Cle Clinic
🛏 Queen bed • 1 bathroom • Sleeps 2 🏛 Historic Cleveland mansion • Second floor studio 🍳 Full kitchen • Smart TV • Streaming apps 🚗 Free off-street parking • Quiet location 💤 Peaceful, comfortable & full of charm 📍 Directly across from Cleveland Clinic Main Campus (10 min walk, 2 min drive) Step back in time while enjoying modern comfort in this bright and colorful studio nestled inside a beautifully restored Cleveland mansion.

Cozy and Warm #1*Family Run*
Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!
Popular amenities for vacation rentals near Case Western Reserve University
Other top sights near Case Western Reserve University
Condo rentals with wifi

Downtown CLE Loft | King Bed | Walk to Everything

Chic home near Cleveland airport

Luxury Top Floor Condo with a View

Retro Nostalgic Condo in the heart of Lakewood

Cozy Condo

Bright and Hip 2BR Condo in Heart of Ohio City

A Cleveland Modern & Historic Apartment 106-1

Tito’s Toast of Cleveland - A Rock & Roll Retreat
Family-friendly house rentals

Unique Home in Cleveland Heights

Cozy + Bright Lakeshore Cottage

Wade Manor-GameRoom, Gym, Office & Fenced Backyard

Cozy Heights Oasis-Walk to Restaurants

Hot Tub! Ohio City Modern Luxury · 2 King Beds

Charming Carriage House in Cleve. Heights

Beaulah Black | Spacious 4BR Near Clinic + Case

Tremont • urban cottage
Apartment rentals with air conditioning

Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic

2BR in Little Italy, 5 min walk to Case & UH

Walkable Little Italy Gem w/ King Bed | Near CWRU

New Luxury Studios | Walk to Cleveland Clinic

Cozy and Quiet Apartment

Flatiron Loft: Free Parking!

Modern 1BR Penthouse | Heart of CLE Views

Walk to Cleveland Clinic | Modern 1BR | Parking
Other great vacation rentals near Case Western Reserve University

Cheerful, Scandinavian, Midcentury 2 bedroom home

Urban Jungle Cottage in Historic Ohio City

Walk to CWRU w KingBed, Balcony, Gym, Parking, WD

Quaint 2BR in Little Italy

Your Main Street Studio

Quiet cozy Near Cedar Road Cleveland heights

Blue Historic House by Cle Clinic, CWRU, Museums

Little Italy · 2 TVs · 2 Cozy Beds · Fast Wifi
Destinations to explore
- Rentals with a washer and dryer Case Western Reserve University
- House rentals Case Western Reserve University
- Apartment rentals Case Western Reserve University
- Fitness-friendly rentals Case Western Reserve University
- Rentals with a patio Case Western Reserve University
- Family-friendly rentals Case Western Reserve University
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Cleveland Browns Stadium
- Headlands Beach State Park
- Gervasi Vineyard
- Mosquito Lake State Park
- Cleveland Metroparks Zoo
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- The Arcade Cleveland
- Laurentia Vineyard & Winery
- Cleveland Museum of Art
- Huntington Convention Center of Cleveland
- Cleveland Botanical Garden
- Cleveland Museum of Natural History
- Playhouse Square
- Crocker Park
- Debonné Vineyards
- Edgewater Park Beach
- Rocky River Reservation





