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Places to stay near Case Western Reserve University

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Top-rated vacation rentals near Case Western Reserve University

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious outdoor area features a jacuzzi next to a dining table with chairs and an umbrella. Stone flooring surrounds the space, while a brick wall provides a rustic backdrop. Decorative lighting adds a calming touch to the environment.
Vacation home in Cleveland
4.98 out of 5 average rating, 308 reviews

New Cleveland Apt: Little Italy! Massage&Hot tub!

Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!

Top guest favorite
A modern kitchen area features gray cabinetry and a stainless steel sink, complemented by a sleek, dark countertop. A black stove and microwave are seen, alongside a refrigerator with a textured finish. White tiles line the backsplash, reflecting light from the overhead fixture.
Home in Cleveland
4.93 out of 5 average rating, 359 reviews

Historic Little Italy Garden Apartment

Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

Guest favorite
The spacious living room features two leather sofas, one adorned with a yellow throw, arranged around a sleek black coffee table. A stone fireplace serves as a focal point, complemented by a wall-mounted TV. Natural light filters in through the large windows.
Apartment in Cleveland
4.87 out of 5 average rating, 82 reviews

Walkable Little Italy Gem w/ King Bed | Near CWRU

Stay in Cleveland’s Little Italy area in a clean 2BR apartment with a king bedroom, queen bedroom, full kitchen, Wi-Fi, and Roku TV. Walk to neighborhood restaurants, bakeries, and coffee shops, with easy access to Case Western Reserve, Cleveland Institute of Music, Cleveland Clinic, University Hospitals, and University Circle. Ideal for up to 4 guests visiting for school, medical appointments, work, or a Cleveland getaway. ⚠️ See full description for temporary construction April - June 2026

Top guest favorite
The modern kitchen features a geometric tiled island with a natural wood countertop. A stainless steel refrigerator and sleek stove are visible against the white brick wall, illuminated by wall-mounted lighting. The space showcases a blend of contemporary design and functional layout.
Apartment in Cleveland
5 out of 5 average rating, 32 reviews

Little Italy 4, Modern 1BR in Little Italy, AC

Experience a one-of-a-kind stay at this boho-chic apartment located in the heart of Little Italy. With its exposed brick walls, hardwood floors, and wooden furnishings, this place has a unique and stylish aesthetic. You can enjoy a cozy dinner in the kitchen and relax on the comfortable sofa while watching TV. The apartment is situated on a quiet side street, walkable to the bustling heart of Little Italy, where you'll find plenty of restaurants, cafes, and shops. Parking on premises, 1 car.

Guest favorite
A spacious living area is presented, featuring a comfortable sofa and a soft area rug. A modern coffee table sits in the center, while a large TV is positioned against the wall. Natural light filters in through sloped ceilings and a nearby window.
Apartment in Cleveland Heights
4.98 out of 5 average rating, 140 reviews

New! “Modernistic Retreat”

Elevate your stay in this bright, elegant and spacious 3rd floor apartment that offers the perfect blend of tranquility and urban convenience. Less than 10 minutes from Cleveland Clinic, 8 min from Case Western University, 17 min from Rock and Roll Hall of Fame, 18 min from Cleveland Browns Stadium, 20 min from Downtown, 28 min from Cleveland Airport and 45 min from Blossom Music Venue. Moments from charmed local neighborhoods such as Coventry, Little Italy, Cedar Fairmont and Lee Rd.

Superhost
The living room features a blue couch, a wooden coffee table, and a green accent chair. Natural light fills the space through multiple windows. A dining area with a table for two is visible, and a modern kitchen is partially seen in the background.
Apartment in Cleveland
4.94 out of 5 average rating, 62 reviews

Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #7

Fully furnished luxury apartment that has been completely renovated combining old-time 19th century charm with modern amenities. Just move in with your suitcase! Within walking distance to the Cleveland Clinic Campus (5 min walk from main hospital). It’s also near University Hospitals, CWRU, Great University Circle, Downtown Cleveland, and Little Italy. This location is perfect for those receiving medical treatments and their families, doctors on rotation, travel nurses, and interns.

Superhost
An open-concept living space is presented, featuring a modern kitchen with stainless steel appliances. A comfortable sectional sofa is adorned with decorative pillows, while a wooden coffee table and two circular side tables complete the area. Soft, natural light illuminates the room through large windows.
Apartment in Cleveland
4.82 out of 5 average rating, 11 reviews

Private Modern Retreat Mins From Clev Clinic & UH

You will love it here! This fully furnished apartment offers a private space with all the modern luxury amenities you need. Walking distance from Cleveland Clinic Main Campus, Louis Stokes VA Medical Center & Rainbow Babies Children's Hospital including top Cleveland Museums. Nestled right off Chester Ave and only 3 miles to I90. 15 mins to Tower City Center Shopping Mall & Downtown Cleveland. Easy access to the Airport via the Red Line Cedar-University Station RTA Train station.

Top guest favorite
A modern living area is filled with warm tones, featuring a comfortable brown sofa and a circular wooden coffee table. A 50-inch TV sits on a media console. The fully equipped kitchen is visible in the background, showcasing sleek cabinetry and bar seating for three.
Apartment in Cleveland
5 out of 5 average rating, 33 reviews

Modern 1B1.5B Loft w/ Gym + Parking

A Perfect Space for the Busy Professional! - Queen bed upstairs + roll‑out twin downstairs - Dedicated desk + fast Wi‑Fi for work - In‑unit foosball table - Access to gym, game room, fire pits & more - Minutes from Cleveland Clinic, UH & Case Western - Clean, modern & easy to settle into - Quick, responsive host to assist with anything you need Please Note: This community is brand NEW! The building is putting on final touches so a few shared amenities may be unavailable.

Guest favorite
A light-filled bedroom features a comfortable bed with a checked comforter and a yellow accent pillow. The space includes a chair and desk, with a cozy sitting area visible through an open door. Bright curtains frame the windows, illuminating the warm wood floor.
Apartment in Cleveland
4.83 out of 5 average rating, 124 reviews

2BR in Little Italy, 5 min walk to Case & UH

Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.

Top guest favorite
The exterior of a charming brick carriage house is showcased, featuring a steeply pitched roof and large, shuttered windows. Lush greenery surrounds the entrance, with flowering plants visible near the driveway, providing a welcoming ambiance on the sunlit day.
Guesthouse in Cleveland Heights
4.98 out of 5 average rating, 537 reviews

Clean and Cozy Carriage House Getaway

Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

Top guest favorite
A modern open-concept living area showcases a dining table surrounded by metal chairs, with a view of the kitchen featuring white cabinetry and appliances. A plush sofa is positioned nearby, and a black cat can be seen casually exploring the space.
Apartment in Cleveland
4.98 out of 5 average rating, 468 reviews

Little Italy - Heart of it all...

Modern, fully furnished, one-bedroom apartment (includes sofa bed for 3rd person). Set up for both short and longer comfortable stays. Cooking utensils supplied; dishwasher, gas stove & microwave; In-suite Laundry Walk, bike or take public transport (Health Line) to University Hospitals and the Cleveland Clinic or to Case Western Reserve University. Restaurants, Museums, & Specialty shops within close walking distance Off-street parking Weekly and Monthly Rates

Superhost
The studio features a spacious bed framed by soft, light-colored drapes and a large mirror above a wooden headboard. A cozy seating area is provided with a black armchair and round table, while an overhead fan adds comfort.
Apartment in Cleveland
4.74 out of 5 average rating, 98 reviews

Peaceful Mansion Studio | Steps from Cle Clinic

🛏 Queen bed • 1 bathroom • Sleeps 2 🏛 Historic Cleveland mansion • Second floor studio 🍳 Full kitchen • Smart TV • Streaming apps 🚗 Free off-street parking • Quiet location 💤 Peaceful, comfortable & full of charm 📍 Directly across from Cleveland Clinic Main Campus (10 min walk, 2 min drive) Step back in time while enjoying modern comfort in this bright and colorful studio nestled inside a beautifully restored Cleveland mansion.

Popular amenities for vacation rentals near Case Western Reserve University