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Apartment vacation rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
A bright room features a spacious bed with light bedding against an arched wall. A small table holds a bowl of oranges. Open windows provide views of the outdoors, complementing the soothing ambiance created by warm lighting.
Apartment in Caceres
4.95 out of 5 average rating, 110 reviews

Plaza Mayor 35's Apartments, Apartment with 2 bed.

Apartamentos Plaza Mayor 35 is the ideal option for travelers interested in getting to know the Monumental Complex of Cáceres. We offer 11 unique apartments located in the Plaza Mayor de Cáceres, two steps from one of the most complete urban complexes of the Middle Ages in the world.The apartments are located in acozy manor house completely renovated with free Wi-Fi, air conditioning hot/cold, fully equipped kitchen, large living room with sofa bed, comfortable rooms and bathroom with shower.

LocationFamilyLong stay

Superhost
A historic stone building is framed by olive trees and illuminated pathways. The structure features multiple balconies and large windows, highlighting the significant architectural details. The surrounding garden includes well-maintained flower beds, creating a serene environment for guests.
Apartment in Conquista de la Sierra
4.89 out of 5 average rating, 9 reviews

Balcony of the Sierra- La Higuera

This accommodation has brick vaults, stonework lintels in the windows and direct access to the courtyard, representing the construction of the S. century. Palace that comes from Francisco Pizarro. In this accommodation you will find a kitchen-living room, a bedroom and a bathroom. It also has a porch with a terrace where you can appreciate the entire courtyard. You can swim in your pool. Perfect for staying with family or friends, and you can book more accommodations.

LocationValueLaundry

Guest favorite
A cozy kitchen area features exposed brick walls and a modern layout. Stainless steel appliances include a washing machine and a stove. A small round table is set for two, complemented by a balcony access door, allowing natural light into the space.
Apartment in Caceres
4.93 out of 5 average rating, 336 reviews

Unbeatable location in Historic Center ATCC00523

The apartment is located in the heart of the Historic Center, declared a World Heritage Site, less than 100 meters from the Plaza Mayor and surrounded by the city's main monuments. In this Monumental Zone you can enjoy important free and outdoor musical events such as Womad, Irish Fleadh, Blues Festival etc. As well as a theater festival and a medieval market. Less than a 5-minute walk away are cafes, restaurants, shops, and public transportation. LIC-AT-CC-00523

FamilyValueSleep quality

Top guest favorite
A bright bedroom features a spacious bed adorned with neutral bedding and decorative pillows. Natural light filters through sheer curtains, and a patterned curtain adds depth to the space. The room connects to a doorway leading to a living area, enhancing the open feel.
Apartment in Merida
4.98 out of 5 average rating, 85 reviews

Javier's Apartments, Family apartment

Spacious flats in the centre of Merida, in a refurbished building from 1881, with all amenities, ideal for visiting and enjoying the city without taking the car. The property consists of 4 flats, 1 and 2 bedrooms, all with balconies or windows to the outside, king size beds, living room, kitchen and private bathrooms for each room, free WIFI, Smart TV, satellite TV. Quality bed linen and towels, bathroom amenities, coffee and tea capsules are included.

FamilyValueGetting around

Top guest favorite
A spacious living and dining area features modern furniture and an artistic wall mural. A dining table is paired with several black chairs, while a comfortable seating arrangement includes a couch and a television. Natural light is allowed through window openings with wooden shutters.
Apartment in Caceres
4.99 out of 5 average rating, 149 reviews

Gran Apartamento Turistico Sir Galahad

Spacious and accessible accommodation, cozy, great views towards the Plaza Mayor and Old Town with all the necessary amenities for your comfort. Views towards the Wall, Arco de la Estrella, City Hall, a few meters away you can find Restaurants, Pharmacy, Pedestrian street of shops, Banks and Taxi Stop. Our apartment is located in the Monumental Zone. With prior authorization that we manage, it can be accessed for loading and unloading of luggage.

ValueLocationCondition

Superhost
A spacious living area features a comfortable sofa and an elegant coffee table. Large windows open to a view of the plaza, allowing natural light to flood in. A decorative wall art piece adds color to the neutral-toned walls, complemented by a compact dining table.
Apartment in Caceres
4.71 out of 5 average rating, 178 reviews

Apartamento Plaza Mayor Cáceres

Beautiful apartment in the main square of Cáceres, has unique views of the historic city, a world heritage site, history is breathed, the apartment has an unbeatable location to enjoy the city and make tourist, gastronomic routes. At the same time the house is spacious and very quiet and comfortable to have an unforgettable stay. The house has been renovated in November 2018 and is fully equipped, so you can feel at home

LocationFamilyGetting around

Guest favorite
A modern living area is highlighted by a grey sofa and two chairs, set against a backdrop of light, textured walls. A small dining table is positioned near a kitchenette, while a television is mounted on the wall. Natural light filters softly through curtain drapes.
Apartment in Trujillo
5.0 out of 5 average rating, 9 reviews

La Pata Suites, Apartment 1

Inaugurado in April 2025 after an integral reform. Personal information will be required from guests under applicable laws. The accommodation has: - living room kitchen equipped with sofa bed 150 x 200 cm, full kitchen and 42 "smart-tv - bedroom with a 150cm double bed and 42"smart-tv - full bathroom integrated into master bedroom - patio equipped with table and outdoor chairs

LocationFamilyAccuracy

Guest favorite
A wide-open landscape is depicted with rolling hills and patches of lush greenery. A large tree stands on the right, while distant mountains are visible under a cloudy sky. The scene conveys a serene and natural setting, ideal for nature lovers.
Apartment in Cabañas del Castillo
4.93 out of 5 average rating, 114 reviews

Charming studio with views

Studio apartment that was once an attic and now welcomes you as if it were a nest. It's small and simple but with handmade and original details that make it different. It's an ideal place for those looking to relax, for nature lovers and trails to walk quietly, without crowds. And it's especially a good place for birdwatching and the night sky.

LocationValueIndoor spaces

Guest favorite
A rustic dining area features a wooden table set with two glasses of red wine, complemented by a selection of charcuterie, cheese, and crackers. A built-in barbecue with brick detailing is visible in the background, providing a cozy cooking space.
Apartment in Trujillo
4.91 out of 5 average rating, 11 reviews

La Casa Del Escudo

A unique accommodation, in a stately home, in the same Plaza Mayor of Trujillo, recently renovated and with all the luxury of details, in which we highlight a rooftop with beautiful views, where you can enjoy a barbecue or some wines with your friends or family, we have 3 bedrooms and an Italian sofa convertible into a double bed

FamilyLocationQuiet

Superhost
A shaded seating area is provided under a large canopy. Natural stone seating surrounds a round table, with lush greenery in the background. A rectangular pool is visible, framed by a well-maintained lawn and decorative flower pots along the fence.
Apartment in Campo Lugar
5.0 out of 5 average rating, 5 reviews

Casa Rural El Miajón2 Near Trujillo

Apartment located in Campo Lugar (Cáceres) consists of 2 bedrooms, the first with a double bed and the second with two single beds, bathroom, kitchen and living room. It also has common areas such as a swimming pool, porch, garden and terrace. Registration Number TR-CC-00359

CleanlinessHospitalityOutdoor spaces

Guest favorite
A modern living space features a pink sofa centered in the room, complemented by a glass coffee table. Below, a transparent floor reveals illuminated ancient Roman ruins. A dining table with chairs is positioned in the corner, and soft natural light filters through sheer curtains.
Apartment in Merida
4.97 out of 5 average rating, 122 reviews

CMDreams Gold, Apartamento proserpina

Exclusive apartment with all the glass floor, where you can see under Roman remains. It has a room on the glass floor; a living room with kitchen and a bathroom.

FamilyLocationKitchen

Top guest favorite
The image features a historical square in Cáceres, showcasing a prominent stone tower and traditional buildings with terracotta roofs. A large yellow sign spelling 'Cáceres' stands in the foreground, while outdoor seating is visible, indicating a vibrant public space.
Apartment in Caceres
4.95 out of 5 average rating, 183 reviews

Casa para 5 personas junto a plaza mayor

A spectacular, recently refurbished home offering 3 bedrooms in the heart of Cáceres and overlooking the city´s Old Town.

LocationValueAir conditioning

Popular amenities for Santa Cruz de la Sierra apartment rentals