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Apartment vacation rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
Rental unit in Cáceres
4.98 out of 5 average rating, 176 reviews

Macarena Suites, historic center (parking free...

Disfruta de apartamentos exclusivos con terraza privada y acceso sin escaleras. Destacamos por nuestra comodidad inigualable: parking privado en el mismo edificio, cerraduras inteligentes para llegada autónoma y equipamiento premium con cocina completa. Alojamiento turístico de dos llaves, acabado de construir en 2025, con plaza de garaje y terraza. Pensando como una vivienda habitual con todas sus comodidades como horno, lavadora, secadora, Smart TV, sofá cama, nevera con congelador amplia, etc. Parking privado: plaza de garaje con acceso directo al interior del edificio (sin salir al exterior). Capacidad máxima 4 personas, como máximo dos adultos y dos niños hasta 17 años. No se permite el acceso a personas no indicadas en la Reserva como huéspedes.

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Top guest favorite
Apartment in Cáceres
4.99 out of 5 average rating, 137 reviews

Room Hands Ciudad Monumental Cáceres

Welcome to your home in Cáceres! A charming apartment in the heart of the old part. A bedroom with a double bed, a bathroom with a shower, and a cozy living room with large windows overlooking the courtyard. Over 100 years old and fully renovated. Air conditioning in the living room (there is a floor fan in the room) and Wi-Fi Next to Plaza Mayor, within the city walls Legal registration is ROOMHANDS AT-CC-324 "The apartment is in the heart of Cáceres's old town, two minutes from the Cathedral

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Top guest favorite
Rental unit in Cáceres
4.95 out of 5 average rating, 543 reviews

Plaza Mayor 35's Apartments

Apartamentos Plaza Mayor 35 is the ideal option for travelers interested in getting to know the Monumental Complex of Cáceres. We offer 10 unique apartments located in the Plaza Mayor de Cáceres, two steps from one of the most complete urban complexes of the Middle Ages in the world.The apartments are located in acozy manor house completely renovated with free Wi-Fi, air conditioning hot/cold, fully equipped kitchen, large living room with sofa bed, comfortable rooms and bathroom with shower.

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Superhost
A historic stone building is framed by olive trees and illuminated pathways. The structure features multiple balconies and large windows, highlighting the significant architectural details. The surrounding garden includes well-maintained flower beds, creating a serene environment for guests.
Apartment in Conquista de la Sierra
4.89 out of 5 average rating, 9 reviews

Balcony of the Sierra- La Higuera

This accommodation has brick vaults, stonework lintels in the windows and direct access to the courtyard, representing the construction of the S. century. Palace that comes from Francisco Pizarro. In this accommodation you will find a kitchen-living room, a bedroom and a bathroom. It also has a porch with a terrace where you can appreciate the entire courtyard. You can swim in your pool. Perfect for staying with family or friends, and you can book more accommodations.

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Guest favorite
A cozy kitchen area features exposed brick walls and a modern layout. Stainless steel appliances include a washing machine and a stove. A small round table is set for two, complemented by a balcony access door, allowing natural light into the space.
Apartment in Cáceres
4.93 out of 5 average rating, 337 reviews

Unbeatable location in Historic Center ATCC00523

The apartment is located in the heart of the Historic Center, declared a World Heritage Site, less than 100 meters from the Plaza Mayor and surrounded by the city's main monuments. In this Monumental Zone you can enjoy important free and outdoor musical events such as Womad, Irish Fleadh, Blues Festival etc. As well as a theater festival and a medieval market. Less than a 5-minute walk away are cafes, restaurants, shops, and public transportation. LIC-AT-CC-00523

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Top guest favorite
A spacious living and dining area features modern furniture and an artistic wall mural. A dining table is paired with several black chairs, while a comfortable seating arrangement includes a couch and a television. Natural light is allowed through window openings with wooden shutters.
Apartment in Cáceres
4.99 out of 5 average rating, 149 reviews

Gran Apartamento Turistico Sir Galahad

Spacious and accessible accommodation, cozy, great views towards the Plaza Mayor and Old Town with all the necessary amenities for your comfort. Views towards the Wall, Arco de la Estrella, City Hall, a few meters away you can find Restaurants, Pharmacy, Pedestrian street of shops, Banks and Taxi Stop. Our apartment is located in the Monumental Zone. With prior authorization that we manage, it can be accessed for loading and unloading of luggage.

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Superhost
A spacious living area features a comfortable sofa and an elegant coffee table. Large windows open to a view of the plaza, allowing natural light to flood in. A decorative wall art piece adds color to the neutral-toned walls, complemented by a compact dining table.
Apartment in Cáceres
4.72 out of 5 average rating, 181 reviews

Plaza Mayor Cáceres Apartment

Beautiful apartment in the main square of Cáceres, has unique views of the historic city, a world heritage site, history is breathed, the apartment has an unbeatable location to enjoy the city and make tourist, gastronomic routes. At the same time the house is spacious and very quiet and comfortable to have an unforgettable stay. The house has been renovated in November 2018 and is fully equipped, so you can feel at home

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Superhost
Rental unit in Mérida
4.84 out of 5 average rating, 141 reviews

Elite Apartments - Art Collection - Vincent, ...

Apartment located on the ground floor of a building. Access is via a few steps. This apartment has 2 bedrooms, one with a 135x190 double bed and the other with a 105x190 single bed, a bathroom with shower, and a living room area with a full kitchen. Both the bedrooms and the living room-kitchen area have a split hot-cold air conditioner. We have equipped the apartment with everything you need to enjoy a pleasant stay.

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Guest favorite
Rental unit in Trujillo
4.95 out of 5 average rating, 40 reviews

La Pata Suites, Apartment 1

Inaugurado in April 2025 after an integral reform. Personal information will be required from guests under applicable laws. The accommodation has: - living room kitchen equipped with sofa bed 150 x 200 cm, full kitchen and 42 "smart-tv - bedroom with a 150cm double bed and 42"smart-tv - full bathroom integrated into master bedroom - patio equipped with table and outdoor chairs

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Guest favorite
A wide-open landscape is depicted with rolling hills and patches of lush greenery. A large tree stands on the right, while distant mountains are visible under a cloudy sky. The scene conveys a serene and natural setting, ideal for nature lovers.
Apartment in Cabañas del Castillo
4.93 out of 5 average rating, 114 reviews

Charming studio with views

Studio apartment that was once an attic and now welcomes you as if it were a nest. It's small and simple but with handmade and original details that make it different. It's an ideal place for those looking to relax, for nature lovers and trails to walk quietly, without crowds. And it's especially a good place for birdwatching and the night sky.

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Guest favorite
A rustic dining area features a wooden table set with two glasses of red wine, complemented by a selection of charcuterie, cheese, and crackers. A built-in barbecue with brick detailing is visible in the background, providing a cozy cooking space.
Apartment in Trujillo
4.91 out of 5 average rating, 11 reviews

La Casa Del Escudo

A unique accommodation, in a stately home, in the same Plaza Mayor of Trujillo, recently renovated and with all the luxury of details, in which we highlight a rooftop with beautiful views, where you can enjoy a barbecue or some wines with your friends or family, we have 3 bedrooms and an Italian sofa convertible into a double bed

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Guest favorite
Rental unit in Mérida
4.87 out of 5 average rating, 254 reviews

CMDreams Gold

Apartamento exclusivo con todo el suelo de cristal, donde se pueden observar debajo restos romanos. Podrás caminar sobre un suelo de cristal y disfrutar de las ruinas romanas visibles e iluminadas debajo. Posee una habitación sobre el suelo de cristal; un salón comedor con cocina y un baño completo.

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Popular amenities for Santa Cruz de la Sierra apartment rentals