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Vacation rentals in Santa Clara

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
Home in Gamboa
4.87 out of 5 average rating, 98 reviews

BirdHouse@ Gamboa Panamá Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Top guest favorite
An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.
Home in Costa Esmeralda
4.98 out of 5 average rating, 184 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favorite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 77 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favorite
The exterior of a modern house is shown, featuring a covered entrance and a driveway with a parked car. Lush green grass and tropical plants add a touch of greenery, complemented by a palm tree. Large windows offer light to the interior spaces.
Home in Panamá
4.81 out of 5 average rating, 16 reviews

Excelente y económica casa en La Chorrera.

La casa es completamente privada, tiene estacionamiento en la entrada, la recámara principal tiene cama doble, aire acondicionado y smart tv de 65” y baño completamente privado, habitación secundaria con cama doble, aire acondicionado y smart tv de 43”, habitación secundaria con cama twin, ventilador y smart tv de 32”, baño compartido. La sala-comedor tiene sofá, mesa de centro, mesa tv con smart tv de 32”, comedor de 4 puestos y la cocina completamente equipada con refrigeradora de 16 pies.

Top guest favorite
An outdoor space features a heated pool surrounded by light-colored tiles. A covered patio includes modern seating arrangements and a table, suitable for dining. Lush greenery is visible beyond the walls, with a glimpse of the sky above, providing a bright and open feel to the area.
Home in Vacamonte
5 out of 5 average rating, 27 reviews

The Hidden Gem

Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Top guest favorite
A balcony area is presented with a small, round table and two folding chairs, offering a view of the ocean. A colorful hammock is hung nearby, surrounded by palm trees, providing a relaxed atmosphere. Glasses sit atop the table, ready for refreshments.
Condo in Vacamonte
4.93 out of 5 average rating, 82 reviews

¡Vista Al Mar y piscina!

Te encantará esta escapada única frente al mar, disfrutando el sonido de las olas, y el ambiente de playa, sol y un amanecer espectacular! Incluido acceso a club privado con piscina y toboganes... y la mejor parte a solo 30km de cuidad de Panama!!! La piscina y toboganes está ABIERTA de Martes a Domingo y *Feriados* en horario de 8am a 5pm. ** Lunes - cerrado por mantenimiento ** El apartamento está ubicado en "Residencial Playa Dorada", queda camino hacia al puerto de Vacamonte.

Guest favorite
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.95 out of 5 average rating, 200 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 218 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favorite
Chalet in Veracruz
4.89 out of 5 average rating, 113 reviews

A beachfront property very near to Panama city

The village name is Veracruz, this is a small fishing village located at the pacific ocean. It´s 20 minutes driving to Panama city. There are public buses or taxis available 24/7 The studio is located in a very quit área of Veracruz. And it´s an ideal place to retrait in the evening and enjoy the tranquility. On the beach of Veracruz are several nice restaurants and bars with live music located

Guest favorite
A modern apartment building is presented, featuring a well-maintained pool area in the foreground. Multiple lounge chairs and tables are arranged neatly around the pool, which reflects the blue sky above. The building showcases large windows, enhancing natural light throughout its levels.
Apartment in La Chorrera
4.89 out of 5 average rating, 38 reviews

The best getaway place in Panama

Enjoy the charmed Panama from our beautiful apartment in Costa Verde, La Chorrera. 30 minutes away from Panama City and 30 minutes away from tipical Panama provinces. Walk distance to the mall, banks, restaurants, pharmacies, stores and much more. Perfect place for you to enjoy all places of Panama. Relax with the whole family at this peaceful place to stay.

Guest favorite
A cozy living area is highlighted by a light-colored wooden table placed on a textured rug. Two comfortable chairs face the table, with a small plant centerpiece and books visible. Natural light floods the space through large windows, revealing lush greenery outside.
Loft in Panamá
4.95 out of 5 average rating, 73 reviews

Canal Loft

Apartamento en 1er Piso, ideal para parejas amantes del buen gusto, tranquilidad y confort. Cerca del apartamento hay senderos hacia el el Canal de Panamá, colinas y selva. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.

Top guest favorite
A spacious living area features a comfortable gray sofa and a stylish wooden coffee table. A swing chair hangs beside a large window, providing natural light. The dining area, with a wooden table and black chairs, is seen in the background, enhancing the open layout.
Home in Gamboa
4.9 out of 5 average rating, 31 reviews

Casa familiar en Gamboa junto al Canal

Gamboa fue fundada en los años 30 por los americanos de la antigua zona del Canal de Panamá. Desconecta de tus preocupaciones en este espacio tan amplio y sereno. Disfruta de paseos en el Canal de Panamá y lago Gatún. Avistamiento de Aves y senderos rodeados de fauna y vegetación.

Popular amenities for Santa Clara vacation rentals