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Guesthouse vacation rentals in Santa Ana

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Santa Ana guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Orange
4.91 out of 5 average rating, 312 reviews

Orange Slice - Near Disneyland, Chapman Univ.

DianaRating, 5 stars1 week ago
Tony and Shelly's "Orange Slice" was excellent. The space was the perfect size. Accommodations were comfortable and the outside space was beautiful and relaxing. Tony and Shelly were very responsive when we had questions and very generous hosts. I would recommend this space to others. We had a great experience!
Top guest favorite
Guesthouse in Corona Del Mar
4.98 out of 5 average rating, 264 reviews

Charming 2 br condo nr. beach

ValeriaRating, 5 stars1 week ago
Absolutely loved our stay in this beautiful Corona del Mar home! The location was perfect—just a short walk to the beach, shops and restaurants. The space was spotless, stylish, and thoughtfully stocked with everything we needed. The host was responsive, kind, and made check-in a breeze. We felt like locals and didn’t want to leave. Highly recommend—this is a gem!
Guest favorite
Guesthouse in Santa Ana
4.87 out of 5 average rating, 134 reviews

Disney Guesthouse Sleeps 7 near the Beaches in O.C

AlejandraRating, 5 stars3 weeks ago
They have great communication with me and didn’t take long to respond.
Guest favorite
Guesthouse in Lakewood
4.91 out of 5 average rating, 119 reviews

Entire Guest Pool House

AndyRating, 5 stars2 weeks ago
Place was an amazing stay. The area was nice and quiet. Entrance to the place was very easy and the place has a pool and outdoor patio with a fire pit which was amazing! Beds and sheets were very comfortable and soft with an AC available. The room has a complimentary coffee station which was amazing!!! The place was clean and aesthetic! Highly suggest this place!
Guest favorite
Guesthouse in Glendora
4.9 out of 5 average rating, 392 reviews

Cozy Guesthouse in Historic Village

MelissaRating, 5 stars3 weeks ago
Thoroughly enjoyed our time at Jacob’s space. It was three blocks from downtown and very easy to move around the area. They were wonderful host house was ex extraordinarily comfortable and had everything we needed for our stay. The space was cozy without feeling crap. We have plenty of room to unpack and plenty of room to move around. We had breakfast either in the dining area or out on the front patio every morning.
Guest favorite
Guesthouse in Eastside Costa Mesa
4.96 out of 5 average rating, 715 reviews

Fully Loaded Newport Beach Studio

RizalinaRating, 5 stars2 weeks ago
Peaceful comfortable place. We loved it. Ryan is very nice. The place is cleaned.
Superhost
Guesthouse in Carson
4.87 out of 5 average rating, 391 reviews

Cozy Place - Unit11

GelseyRating, 5 stars1 month ago
The house was easy to find, have clear instructions to check in and check out, the owner communicated everything with detail, I felt like a really comfy place with any essential you need on your stay
Top guest favorite
Guesthouse in Chapman
4.96 out of 5 average rating, 287 reviews

Two-room Cottage/Kitchen/Tennis Ct/Pool 独立俩房/厨房/泳池

JenniferRating, 5 stars5 days ago
First time in california and felt right at home. There’s so much to do around the area and we visited LA frequently throughout our stay. Sarah was super sweet and friendly, she let us drop off our luggage earlier than our check in time and gave us a mini tour of the beautiful guesthouse along with its amenities. We felt super comfortable and right at home. 10/10 would highly recommend.

Guest house rentals with a patio

Guest favorite
Guesthouse in Altadena
4.91 out of 5 average rating, 180 reviews

Adorable Back House w/Secluded Garden & Yard

OliverRating, 5 stars2 weeks ago
This place is absolutely stunning, with one of the most beautiful front and back gardens I’ve ever seen. The backyard was a peaceful spot to relax, and the pool added quite a bit of luxury. I didn’t meet Geoff, but Daren was incredibly warm and welcoming—easily one of the best hosts I’ve had, striking the perfect balance between friendliness and giving space. Has the basic kitchen essentials, hot plate in a drawer, kettle, toaster oven, microwave, wine fridge; it’s PLENTY for a short stay. The guest house feels closely connected to the main home, and the vibe was nothing but positive! I’d stay here again in a heartbeat—10/10 experience
Top guest favorite
Guesthouse in Eagle Rock
4.99 out of 5 average rating, 122 reviews

Private Spanish Guesthouse w/ Pool & Views

AvishiktaRating, 5 stars1 week ago
We had a wonderful stay at Pablo's house, which was not only beautiful but also felt like home. The house was immaculately clean, with a comfortable bed and bathroom, and its cozy atmosphere made it perfect for a couple. The neighborhood was very safe, with no parking issues, and the hosts were extremely friendly and responsive. We're grateful they shared their lovely home with us.
Guest favorite
Guesthouse in South Gate
4.93 out of 5 average rating, 179 reviews

Guest house unit B

MaheshRating, 5 stars1 day ago
This is a great place and Maricela is a gold-star host and person. Highly recommend. Will stay again.
Guest favorite
Guesthouse in Long Beach
4.92 out of 5 average rating, 145 reviews

Adorable 1 bedroom house with pool and patio

DonnishaRating, 5 stars2 months ago
Lovely place! Looks better in person and has a real homey feel to it, which makes you instantly comfortable. It also smelled really good upon entry which I appreciated. I would definitely recommend.
Top guest favorite
Guesthouse in Monrovia
4.98 out of 5 average rating, 178 reviews

Modern Hillside Escape surrounded by Nature

IbrahimRating, 5 stars2 weeks ago
I stayed at Dana’s place in Monrovia, CA for a couple of days and had a great experience. The space was super clean, peaceful, and relaxing—just what I needed. Dana was incredibly supportive; when I was confused during check-in, she showed up right away to help. The location is perfect for me since I come to the area for work once a month, it's close to the business and also near great hiking trails and restaurants. Most importantly, the neighborhood feels very safe. Highly recommend!
Top guest favorite
Guesthouse in Upland
5 out of 5 average rating, 103 reviews

Runaway Inn Minutes from Claremont/Pomona Colleges

DanielleRating, 5 stars1 week ago
Loved staying at Tammy’s place! This was a perfect airbnb we wished we could move in! Tammy provided so much. All of the cooking items and many spices. Bathroom came with all toiletries. The ac and electric fire was sooo nice and romantic!! We absolutely hated that we had to leave. The star jasmine outside was EVERYTHING!
Guest favorite
Guesthouse in Downey
4.87 out of 5 average rating, 135 reviews

Guest house has private Entrance

StephenRating, 5 stars3 days ago
Had a great stay. It was everything advertised, very clean, Albert was all ways very helpful. Would love to stay again.
Top guest favorite
Guesthouse in Burbank
4.98 out of 5 average rating, 263 reviews

Private Guest Quarters with Patio & Bathroom

ChrisRating, 5 stars1 day ago
I had a great stay and highly recommend this Airbnb if you are a solo traveler. It was very clean, updated, and well stocked. I felt safe and the hosts were very nice. I will definitely book again when I am in town to visit my daughter!

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Santa Ana
5 out of 5 average rating, 22 reviews

Guest Suite in Santa Ana

JoshRating, 5 stars1 week ago
We loved our stay! Very quiet and chill neighborhood, very conveniently located for exploring everything in the area. We had a couple extra requests and I appreciate the immediate and helpful responses. We'll gladly stay here again!
Top guest favorite
Guesthouse in La Verne
4.98 out of 5 average rating, 348 reviews

Villa del Sol in La Verne, CA Private Home

ScottRating, 5 stars1 week ago
Fantastic stay, well worth the price. The pool house feels like it's right out of the 30's or 40's. The pool itself was right out of the same time period with lavender lining one side and table and chairs on the other. The place was spotless and wonderful to stay in. I loved every minute of it. Kim did a fantastic job decorating the space. She was responsive and friendly. Just what I needed.
Top guest favorite
Guesthouse in Placentia
4.95 out of 5 average rating, 156 reviews

1919 Spanish Casita | 12 min. to Anaheim

AnnieRating, 5 stars1 month ago
I had a great stay at Jana's place with my 5 year old toddler. We had minor issue with wrong keypad during checkin. But Jana was responsive and we figured it out. The house is small, quite, clean and cozy. Kitchen had good amenities for light meal preps. The outdoor garden is beautiful. Jana was sweet to add a small step stool for my daughter and also gave us some toys for her to play with. My daughter was excited and noticed the small details.
Top guest favorite
Guesthouse in South Coast
4.95 out of 5 average rating, 21 reviews

Disneyland Neighbor Studio

WilliamRating, 5 stars4 days ago
Super nice place, much better than a hotel. Happy I found her place and will try to stay here again if available on my next trip!
Guest favorite
Guesthouse in Alhambra
4.89 out of 5 average rating, 138 reviews

Private Entrance/Bathroom Free Parking King Bed

Krystyna Rating, 5 stars3 weeks ago
Great place. Quiet, felt very safe. Host was very accommodating and pleasant. I was extremely happy with my stay and the price. Would love to stay here again on my next visit out.
Guest favorite
Guesthouse in El Monte
4.94 out of 5 average rating, 216 reviews

Cozy Lemon Tree Guest Studio with Garden

MarielRating, 5 stars1 week ago
Such a lovely airbnb to stay in. Me and my friend enjoyed the lemon tree. As long as you followed the instructions, finding the place was easy. Very responsive if any issues were to occur during the stay.
Guest favorite
Guesthouse in Gardena
4.91 out of 5 average rating, 412 reviews

Southbay Hideaway: Garden Oasis featuring hot tub!

Lynette MarileidyRating, 5 stars1 week ago
Great hosts, awesome spot. Loved it
Guest favorite
Guesthouse in Santa Ana
4.91 out of 5 average rating, 107 reviews

Welcom 3bedroom,2bath guesthouse Westminster OC

MaryRating, 5 stars1 week ago
The stay was good came to Disney felt like home everything clean.

Quick stats about guesthouse rentals in Santa Ana

  • Total rentals

    80 properties

  • Nightly prices starting at

    ﺩ.ﺇ184 before taxes and fees

  • Total number of reviews

    7K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

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