Guesthouse vacation rentals in Santa Ana

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Santa Ana

  • Total vacation rentals

    Explore 80 vacation rentals in Santa Ana

  • Nightly prices starting at

    Santa Ana vacation rentals start at ﺩ.ﺇ 257 per night before taxes and fees

  • Verified guest reviews

    Over 8,130 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    80 of Santa Ana vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Ana rentals

  • 4.9 Average rating

    Santa Ana stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated guesthouse rentals in Santa Ana

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern living area features a light-colored sofa and a wooden coffee table placed on a soft area rug. In the background, a dining table with chairs is visible, alongside a well-equipped kitchen with wooden cabinets. Natural light brightens the space through large windows.
Guesthouse in Santa Ana
4.97 out of 5 average rating, 202 reviews

Cozy 2-bedroom private guesthouse near South Coast

Step into this getaway house, away from all the hustle and bustle of daily life. You will find calmness and peace on your vacation. Indulge in a hot cup of coffee under the patio in a quiet environment or make your family a hot breakfast in the new kitchen before you head out to nearby attractions. Just bring your sun glasses and luggages. 5 minutes from South Coast Plaza. 25 Minutes from Disneyland Park. 20 minutes from all beautiful beaches, shopping centers and top restaurants of the region.

Guest favorite
The master bedroom features two queen beds with patterned bedding and a large closet. Natural light enters through multiple windows, and the room is accented by a plush area rug that enhances the space's comfort.
Guesthouse in Santa Ana
4.78 out of 5 average rating, 253 reviews

Pri. GH to Disneyland 5 mins. Christ Cathedral C

Hi Everyone! Welcome to my beautiful private guest house. There’s one master bedroom with a lovely closet and two queen memory foam beds. In the private house there’s also a very roomy living room with a reversible sofa bed. In the living room there’s a nice fireplace and a 55” inches TV with Netflix connection. There’s also a kitchen, laundry room and 1 bathroom. You will truly enjoy living in this wonderful newly built private guest house. There’s also HS WiFi and it’s own private pathway.

Top guest favorite
A well-lit kitchenette is equipped with a full-size refrigerator, electric skillet, and microwave. Natural light enters through large windows adorned with sheer curtains. A small basket holds snacks, while essential kitchen tools are organized on the counter, creating a functional space for simple cooking.
Guesthouse in Santa Ana
4.95 out of 5 average rating, 1,410 reviews

Quiet Peaceful Studio

Private studio apartment. Second-story unit, set back from the street, in a separate building behind the hosts' home. Located in a beautiful historic neighborhood, on a quiet street shaded by oak trees. Disneyland and the Anaheim Convention Center are only 10 minutes away. The Honda Center and Anaheim Stadium 5 minutes. The beaches are an easy 20 minute drive. Excellent restaurants and shopping are abundant. Close to Old Town Orange, Chapman University, and the Santa Artists Village.

Guest favorite
The spacious studio features a queen-size bed framed by minimalist decor. A comfortable sofa bed is positioned opposite a sleek coffee table. Large windows bring natural light into the room, while a stylish light fixture adds a modern touch to the space.
Guesthouse in Santa Ana
4.91 out of 5 average rating, 277 reviews

Lux Upper-Level Guest House 3mi to Disney Magic

Step into our inviting and snug haven! Our AirBnB is for anyone seeking a practical and budget-friendly lodging option. Situated in a secure and welcoming community, it offers seamless access to public transit and a plethora of eateries, coffee houses, and stores. Additionally, it's strategically placed near popular spots like Disney, Knotts Berry Farm, and Angel Stadium. Be it a work trip or a leisurely escape, our AirBnB promises a cozy abode away from home. We can't wait to host you!

Top guest favorite
A neatly organized kitchen features dark blue cabinets and light countertops, enhancing the functional space. Stainless steel appliances, including a gas range and microwave, are prominently displayed. A washing machine is positioned to one side, offering convenience for guests.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 214 reviews

Near Disney, Private, Fast Wifi, Self Check-in

Private Guesthouse in the Heart of Orange County! Enjoy your own peaceful retreat in this newly built, detached guesthouse nestled in a quiet residential neighborhood. This bright and modern space offers complete privacy with its own entrance and a fully fenced patio—perfect for morning coffee or evening relaxation. Centrally located in Orange County, you’ll be just a short drive from top attractions, beaches, shopping, and dining, while still enjoying a calm, cozy place to unwind.

Top guest favorite
Guesthouse in Stanton
4.96 out of 5 average rating, 281 reviews

Spacious & Central just 11 Min 2 Disney & ConvCntr

The price you see is the final price. There is NO hidden additional taxes! 🚗 Short 12 minute drive to Disneyland & Convention Center 🅿️ Free parking 🚪 Private Entry 🌐 Fast Wi-Fi 📺 55" Smart TV ☕ 14-cup coffee brewer ❄️ Air Conditioning & Heater 🍼 Pack 'n Play & Children’s dinnerware 🧺 Washer and Dryer 👩‍🍳 Private Fully equipped Kitchen 🧻 Towels, Blowdryer, Shampoo, Conditioner, & Body wash 👔 Iron & ironing board 🛏️ Additional memory foam floor mattresses available

Top guest favorite
Guesthouse in Santa Ana
4.98 out of 5 average rating, 126 reviews

Cozy 1BR-KingBed+SofaBed 6mi Disney 1.6mi Hosp

Luxury Unit with King-Size Bed, Relax and unwind in our fully equipped unit. With everything you need for a comfortable and enjoyable stay, you're sure to have a memorable time. The unit features: Spacious bedroom with a king-size bed, 54" TV, and a Desk. The Living-room has a sofa bed, making it the perfect place to relax. The kitchen is fully equipped with everything you need. Whether you're on a business trip, vacation, or simply need a place to stay for a few nights.

Top guest favorite
Guesthouse in Santa Ana
4.95 out of 5 average rating, 101 reviews

15 min Disney/SNA Airport - Cozy, Safe Studio Apt

Welcome to the perfect stay for solo or couple travelers. Cozy studio, centrally located within 15 mins of main Orange County tourist destinations! *CENTRALLY LOCATED* + Miles Square Park (2mi) + Asian Garden Mall/Phuoc Loc Tho (2mi) + Anaheim Convention Center (4mi) + The Observatory (4mi) + Disneyland (6mi) + South Coast Plaza (6mi) + Angel's Stadium (8mi) + OC Fairgrounds (8mi) + John Wayne/SNA Airport (9mi) + Knott's Berry Farm (10mi) + Huntington Beach Main St. (10mi)

Top guest favorite
The living area features a comfortable tan leather sofa paired with a woven storage ottoman. Natural light pours in through expansive sliding doors, leading to a private patio. A staircase with a black railing elegantly ascends beside the textured gray wall.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 261 reviews

D'Loft By JC

D'Loft is newly built in July 2023. Your family will be close to everything when you stay at this centrally-located place. We are located 10-15 Min from Disneyland, the beach, shopping and much more! D'Loft features an open concept design, dressed in high end appliances and it's own private patio. Relax in a comfy Cal King Bed in addition to a queen size sofa bed + a twin sleeper, available at your disposal. Open the double sliders and make indoor outdoor space!

Top guest favorite
A cozy sitting area features a day bed adorned with soft, neutral-colored pillows. A decorative chest sits in front, complemented by warm wall sconces. Light enters through the windows, illuminating the shiplap walls and wooden accents that enhance the inviting space.
Guesthouse in Fullerton
4.96 out of 5 average rating, 713 reviews

The Lemondrop Cottage

This is the most charming tiny studio cottage with separate entrance, and a private brick patio in a family friendly neighborhood in the Sunny Hills area of Fullerton, and is a short drive to great restaurants, and lots of activities including Disneyland and Knotts Berry Farm. Tucked away at the back of our home, affording guests ample privacy, and easy parking for one car on the driveway. Please note our place is tiny just as we advertise it as.

Top guest favorite
Guesthouse in La Verne
5 out of 5 average rating, 133 reviews

5-Acre Stay at The Emerald Grove

Hillside Guesthouse on 5 Acres! One of the last original orange grove homes, our property sits next to a nature preserve for a peaceful escape. Though private and serene, we're minutes from Claremont Colleges, Webb School, and local shopping. Enjoy a quiet retreat after a day of exploring, visiting family, or business. Your guesthouse features a private entrance, ample parking, and thoughtful amenities to make your stay comfortable.

Guest favorite
A bright sleeping area is accentuated by a wooden accent wall and colorful decorative pillows on the bed. A small desk is set against the wall, featuring a laptop and a vase with fresh flowers. Natural light fills the space through a nearby window.
Guesthouse in Little Saigon
4.8 out of 5 average rating, 107 reviews

Simple Stylist Guesthouse

Guesthouse 1 bedroom, queen bed, and a bathroom with separate entrance. Before booking, PLEASE READ THIS: 1.For safety purposes, address on Airbnb is proximate. We'll send the exact address after booking is confirmed. 2.This is not HOTEL, so it's more casual and homey feel. If you are looking for HOTEL STANDARD, please book Hotel instead. 3. If you are a picky and have high standards, please book somewhere else.

Popular amenities for Santa Ana guesthouse rentals

When is the best time to visit Santa Ana?

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Avg. priceﺩ.ﺇ 466ﺩ.ﺇ 485ﺩ.ﺇ 481ﺩ.ﺇ 415ﺩ.ﺇ 441ﺩ.ﺇ 459ﺩ.ﺇ 474ﺩ.ﺇ 455ﺩ.ﺇ 422ﺩ.ﺇ 437ﺩ.ﺇ 455ﺩ.ﺇ 496
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Destinations to explore