
Vacation rentals in San Lorenzo District
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in San Lorenzo District
Guests agree: these stays are highly rated for location, cleanliness, and more.

Sand Dollar Villa by the sea at Boca Chica Panama
Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!
ValueFamilyComfort

Entire house with private pool facing beach !
Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.
LocationFamilyGrill

Escape to your oceanfront retreat: Sea La Vie!
This stunning new home, offers a 2-bedroom, 2.5-bath main house and a separate studio casita, hosting up to six guests. Enjoy open living spaces, a gourmet kitchen, and panoramic ocean views. Solar-powered and nearly off-grid, with Starlink Wi-Fi for modern comfort. Surrounded by wildlife and waves, it’s a peaceful sanctuary where luxury meets nature.Wake to howler monkeys calling at dawn and fall asleep to the symphony of tree frogs and gentle surf. Your forever paradise in Playa Hermosa.
FamilyLocationView

Las cabañas del francés - Nature & comfort
Descubra nuestro complejo de 6 cabañas de madera, equipadas con cocina, cama king y dos individuales en el altillo. Disfrute de una vista espectacular al barranco y un entorno natural impresionante. Estamos a 15 min de Boquete y 25 min de David en carro, lo que permite disfrutar de la tranquilidad sin alejarse de la ciudad. Áreas comunes con piscina y barbacoa para momentos inolvidables. Viva una experiencia única, combinando confort moderno y naturaleza en armonía.
FamilyLocationLayout

CasaMonèt
Suite with separate entrance: covered parking, double bed, bathroom, kitchenette and desk. Your personal space in the heart of David. It has split air conditioning, a ceiling fan, a TV with Netflix access, free WiFi internet, blackout curtains, a water reserve tank, hot water, a kitchenette equipped with an electric stove, a refrigerator, a coffee maker, a microwave, and basic utensils. It does not have a laundry room, electric generator, or soundproofing.
FamilyLocationHospitality

Escape with a panoramic view
Welcome to Escape with panoramic views, a modern and cozy apartment in Santa Cruz Tower, David. Enjoy a spectacular view from the balcony, queen size bed, air conditioning, desk, Wi-Fi, private bathroom and hot water. Located in a quiet area, but minutes from shopping malls such as Federal Mall and Plaza Terronal, restaurants, supermarkets and businesses. It also has direct access to Boquete, Chiriquí's most popular mountain destination. English or Spanish!
LocationValueGetting around

Cozy and relaxing house with a terrace
Relax with the whole family in this quiet place, just 10 minutes from downtown David and 25 minutes from the tourist Boquete. Close by you'll find shopping malls, restaurants and services, but far enough away from the hustle and bustle of the city. A safe, comfortable space full of details to enjoy your stay. Safe house with 3 bedrooms, Café-Bar style terrace, patio with barbecue and gazebo, air conditioning and all the amenities to enjoy your stay.
LocationFamilySleep quality

Stunning seaside villa with pool and jacuzzi
Wake up to these second to none ocean views that are always changing with high tide and low tide. The house is located inside the Hermosa Bay residence on the front line of the beach to which the residents have private access. Spacious with all amenities, including a jacuzzi, BBQ and three different fitness machines. The house uses solar energy so never suffers from power outage. The rental comes with usage of the remote controlled garage.
FamilyLocationCheck-in

Finca Colibri
A modern bungalow with unique views of the mangroves of Bajia de Muerte Bay, located in the heart of a nature reserve. The bungalow is very private and quiet. It's just a few minutes drive to the nearest beach. You can expect a fully equipped kitchen, a modern furnished panoramic bathroom and a very comfortable king size bed. By request we can also organize boat trips to the islands, yoga as well as horseback riding and fishing trips.
LocationValueAir conditioning

Best alpine cabin with jacuzzi and amazing weather
Alpine cabin located between Boquete and Volcán. Set in a very peaceful area and fully equipped so you can enjoy an amazing vacation. It features a terrace and a balcony with views of Volcán Barú and the ocean. It also has a hot-water jacuzzi so you can take relaxation to the next level. Paraíso is known for its excellent climate, rivers, lush vegetation, canopy tours, and hiking trails so you can make the most of your stay.
LocationValueOutdoor spaces

Private Beachfront Getaway
Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.
ValueLocationSleep quality

beach house: Villa Pacifica
Villa Pacifica, by far your best choice on the Pacific Ocean. constructed this year, at 30 mt from the private beach of our farm Punta Vittoria in Boca Brava island. Your own beachbar, boat dock, situated in our valley, guaranteeing your total privacy. 3 bedrooms/bath,totally equipped kitchen, large terrace, AC, fresh water pool,and elegantly decorated. A unique blend of nature, wildlife and ocean living.
FamilyLocationBeach
Popular amenities for San Lorenzo District vacation rentals
Other great vacation rentals in San Lorenzo District

Modern and spacious Doral House
LocationFamilyGetting around

HarveyHouse: safe, quiet, 3-bedroom house
LocationFamilyAmenities

Wanakaset River Front Charming 2BR, shared Pool
LocationFamilyRiver

Modern house via airport
FamilyLocationWifi

Cozy country house in Caldera, Boquete.
LocationFamilyCondition

Enjoy Nature
ValueLocationAccess

A BEACHLOVER'S PARADISE, serene, large estate home
FamilyLocationIndoor spaces

Jungle House (El Refugio la Brisa del Diablo)
ValueLocationSleep quality
Destinations to explore
- Panama City Vacation rentals
- San José Vacation rentals
- Tamarindo Vacation rentals
- Jaco Vacation rentals
- Cahuita Vacation rentals
- Quepos Vacation rentals
- Cobano Vacation rentals
- Bahía Ballena Vacation rentals
- Nosara Vacation rentals
- Sámara Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Liberia Vacation rentals





