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Vacation rentals in San Lorenzo District

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Top-rated vacation rentals in San Lorenzo District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern kitchen space is featured with a large island topped with granite. Black padded stools are positioned at the island. The cabinetry combines light and dark finishes, with stainless steel appliances visible. A dining area with a wooden table and decorative accents creates a functional setting.
Home in David
5 out of 5 average rating, 19 reviews

Enjoy David! House 3, comfortable, best location

This accommodation is ideal for group trips of up to 6 and a maximum of 8. A fully remodeled house, luxury finishes, full kitchen, with an island, 3 bedrooms, 1 king size bed, 1 queen size bed, 1 twin size bed and a double sofa bed, 3 bathrooms, 2 of them in the bedrooms, closets and W. Closet in master bedroom. Parking with electric gate. Quiet and residential place. Suitable for family outings or groups. Close to Pan-American Highway in David, close to Plaza Las Terrazas, public transportation very close.

Top guest favorite
A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.
Villa in Boca Chica
4.96 out of 5 average rating, 103 reviews

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

Top guest favorite
A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.
Home in Playa Hermosa
5 out of 5 average rating, 44 reviews

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

Superhost
A pathway flanked by vibrant tropical plants leads to an entrance. The wooden walkway is bordered by low greenery and lit by soft, glowing lights. The landscape reflects a serene outdoor environment, complemented by clear blue skies above.
Tiny home in Alto Boquete
4.81 out of 5 average rating, 171 reviews

10 min to Boquete I Cabaña Rio Vista 2-Free coffee

🌿 New Cabin in Boquete – Nature and Spectacular Views • 🌊 Direct access to a beautiful natural river • 🌄 Access to viewpoints with stunning panoramic views •• 🍳 Electric stove (no oven) and coffee maker • 🌬️ Cool mountain climate • 📍 2 minutes from the David-Boquete road • 🐶 Maximum 2 small dogs allowed • 🚗 Last stretch of stone (small car passes without problem) • 🫒 Complimentary coffee, sugar, salt, pepper, cream, and olive oil • 🕒 Check-in 3 pm | 🕛 Check-out 12 noon

Guest favorite
A wooden cabin with a sloped roof is set amidst a lush green landscape. A well-maintained lawn features decorative plants and trees, while a pathway leads to the entrance. Large glass doors reveal a glimpse of the interior space.
Cabin in Alto Boquete
4.84 out of 5 average rating, 258 reviews

Las cabañas del francés - Nature & comfort

Descubra nuestro complejo de 6 cabañas de madera, equipadas con cocina, cama king y dos individuales en el altillo. Disfrute de una vista espectacular al barranco y un entorno natural impresionante. Estamos a 15 min de Boquete y 25 min de David en carro, lo que permite disfrutar de la tranquilidad sin alejarse de la ciudad. Áreas comunes con piscina y barbacoa para momentos inolvidables. Viva una experiencia única, combinando confort moderno y naturaleza en armonía.

Top guest favorite
A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.
Guest suite in David
4.97 out of 5 average rating, 507 reviews

CasaMonèt

Suite with separate entrance: covered parking, double bed, bathroom, kitchenette and desk. Your personal space in the heart of David. It has split air conditioning, a ceiling fan, a TV with Netflix access, free WiFi internet, blackout curtains, a water reserve tank, hot water, a kitchenette equipped with an electric stove, a refrigerator, a coffee maker, a microwave, and basic utensils. It does not have a laundry room, electric generator, or soundproofing.

Superhost
A spacious living area features large windows allowing natural light to flood the space. A blue sofa is complemented by decorative pillows. Textile art in various shades of blue adorns the walls. A wooden table with chairs is positioned for dining or relaxation, with greenery visible outside.
Villa in San Lorenzo District
4.85 out of 5 average rating, 20 reviews

Villa Turquesa with sea view in Isla Boca Brava

Welcome to Villa Turquesa, a true hidden gem on the stunning Boca Brava Island. This tropical retreat blends luxury, comfort, and adventure—all with spectacular ocean views. It accommodates up to 8 guests, features a fully equipped kitchen, shared pool, free WiFi, and easy access to Playa Las Cocas, just a 25-minute walk from the villa, as well as trails where you can spot birds and howler monkeys. Book Villa Turquesa now and let the sea breeze do the rest!

Guest favorite
Home in Los Algarrobos
4.94 out of 5 average rating, 163 reviews

Cozy and relaxing house with a terrace

Relax with the whole family in this quiet place, just 10 minutes from downtown David and 25 minutes from the tourist Boquete. Close by you'll find shopping malls, restaurants and services, but far enough away from the hustle and bustle of the city. A safe, comfortable space full of details to enjoy your stay. Safe house with 3 bedrooms, Café-Bar style terrace, patio with barbecue and gazebo, air conditioning and all the amenities to enjoy your stay.

Guest favorite
A spacious bed is centered in a room with vibrant green walls. Decorative pillows are arranged neatly on the gray bedding, complemented by a bedside table with a lamp. Art featuring a flower and a hummingbird adorns the wall above the bed.
Bungalow in Boca Chica
4.94 out of 5 average rating, 79 reviews

Finca Colibri

A modern bungalow with unique views of the mangroves of Bajia de Muerte Bay, located in the heart of a nature reserve. The bungalow is very private and quiet. It's just a few minutes drive to the nearest beach. You can expect a fully equipped kitchen, a modern furnished panoramic bathroom and a very comfortable king size bed. By request we can also organize boat trips to the islands, yoga as well as horseback riding and fishing trips.

Guest favorite
A welcoming cabin is shown with a covered porch featuring colorful hammocks and a small wooden chair. Soft lighting illuminates the entrance, while surrounding greenery and cultivated plants complement the natural setting.
Cottage in Caldera
4.89 out of 5 average rating, 161 reviews

Cozy country house in Caldera, Boquete.

Relax with the whole family at this peaceful place to stay and enjoy nature, beautiful rivers, hot springs, waterfalls, hiking, good weather, with access to local mini shops and typical restaurants in the area, a terrace for BBQ and much more! It's a super quiet place, with a lovely view. One-bedroom cabin with a full bed, a large sofa bed. A fully-equipped kitchen. Bathroom with hot water. Indoor parking. Recently Wi-Fi. 👌

Guest favorite
The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.
Home in Playa Nanzal
4.86 out of 5 average rating, 37 reviews

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

Guest favorite
Cabin in Boquete
4.93 out of 5 average rating, 14 reviews

Cabin in Alto Boquete 2

Welcome to Cabañas Piedra del Risco. Our cabanas were designed to offer the perfect balance between modern and rural. From the terrace you will see the majestic Volcán Barú and the canyon of the Caldera river, you will be surrounded by nature and the unique tranquility of Boquete. We are just 12 minutes from downtown Boquete, close enough to explore, and far enough to disconnect.

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