Vacation rentals in Isla Grande

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Top-rated vacation rentals in Isla Grande

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Guest favorite

Home in Corregimiento de Isla Grande

4.96 out of 5 average rating, 83 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Mar 6 – 13

ﺩ.ﺇ1,846 per night

Superhost

Condo in Colón

4.86 out of 5 average rating, 167 reviews

HIDDEN BEACH RESORT & MARINA

The project is located in the Republic of Panama, in the coastal zone of Costa Arriba in the Caribbean Sea. You can spend the day preparing your BBQ in an oceanfront Bohío or if you prefer to delight in the delights of the Kayuco Restaurant located in the Club House. The project features activities with and at no cost depending on season, consult the administration office or the owner of the apartment. It has a swimming pool, lagoon, water park, games for children, sports fields, 2 islands.

Aug 30 – Sep 6

ﺩ.ﺇ982 per night

Guest favorite

Apartment in Juan Gallego

4.85 out of 5 average rating, 157 reviews

Pebos Reef, apt #1, Amazing location !

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Jul 3 – 10

ﺩ.ﺇ716 per night

Guest favorite

Villa in Portobelo

5.0 out of 5 average rating, 42 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Apr 18 – 25

ﺩ.ﺇ905 per night

Guest favorite

Loft in Panamá

4.91 out of 5 average rating, 179 reviews

Amazing Loft with the Best view of Casco viejo!

Hermoso loft ubicado en el centro de Casco Antiguo, la zona más turística de Panamá. Ven, disfruta y relájate en este impresionante loft, con una vista increíble de la Catedral de Panamá. Puedes visitar museos, bares, restaurantes e iglesias ubicados a tan solo unos cuantos metros de distancia. Beatiful Loft located in the center of Casco Antiguo, Panama´s most turistic location. Come, enjoy and relax at this amazing loft, with amazing view to Panama´s Cathedral.

Mar 18 – 25

ﺩ.ﺇ416 per night

Superhost

Cottage in Palenque, Colón

4.87 out of 5 average rating, 70 reviews

Tropical Retreat in the Caribbean:Beachfront House

Rustic and cozy remote cottage in front of the Caribbean with 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in argentinian parrilla, ideal for BBQs. Enjoy this remote cottage with its almost private beach surrounded by beautiful palm trees along the whole area. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise.

Oct 8 – 15

ﺩ.ﺇ1,077 per night

Guest favorite

Condo in Maria Chiquita

5.0 out of 5 average rating, 19 reviews

Playa Escondida Lux Beachfront Haven:Oceanview Apt

Waking up to the Caribbean blue from your balcony, coffee in hand, is possible in this home. Direct beach access upon opening the door and just an hour from the city. Enjoy paradise without walking. We offer WiFi and a peaceful workspace, your perfect escape! We have 4 cozy rooms where you can enjoy everything the Caribbean has to offer Find the perfect blend of luxury and nature. Book now and don't miss out on a home away from home.

Oct 11 – 18

ﺩ.ﺇ1,805 per night

Guest favorite

Home in Cacique

5.0 out of 5 average rating, 19 reviews

El Paraiso

We are happy to introduce you to a large beautiful house for rent between the village of Cacique and the village of José Pobre in the Portobelo National Park. Overlooking the Caribbean Sea, nestled in the jungle , this house has a unique character in the area . Its direct access to a small wild beach, with an exciting reef for snorkeling fans makes it a great place. Ideal for groups and families wishing to connect with nature .

Jan 28 – Feb 4

ﺩ.ﺇ1,050 per night

Guest favorite

Villa in Maria Chiquita

4.9 out of 5 average rating, 50 reviews

Villa en Playa Escondida Resort

Playa hidden Resort & Marina, is a jewel of the Caribbean , one of the most beautiful and exclusive beaches, one hour from Panama City or the Airport , located in Maria Chiquita, Columbus. The project is growing , currently there are constructions in development. Our exclusive Villa , has a terrace with BBQ, natural temperature Jacuzzi and low pumping system, direct access to the pool and a 1 mint walk to the beach .

Jul 7 – 14

ﺩ.ﺇ1,274 per night

Guest favorite

Villa in Cacique

5.0 out of 5 average rating, 23 reviews

CARA AL MAR Cacique

In the middle of the Parque National de Portobello (access only by 4x4), nestled at the top of the hill, between sky and sea, away from all eyes, at the first lodges, a small cozy love nest to rest and disconnect (as a couple or with friends), comfortable, bright (large and high windows), spacious, cool (central air conditioning), witness of a grandiose show... awaits you...!

Nov 23 – 30

ﺩ.ﺇ1,396 per night

Superhost

Home in Palenque

5.0 out of 5 average rating, 4 reviews

Caribbean Paradise - Beachfront Getaway

Welcome to our beachfront paradise in Palenque, Colón, Panama! Nestled along the stunning coastline, this spacious and inviting house offers the perfect retreat for your group getaway. With direct beach access, you'll wake up to the soothing sounds of the waves and the breathtaking views of the ocean right outside your doorstep.

Jul 10 – 17

ﺩ.ﺇ1,775 per night

Guest favorite

Cottage in Panamá

4.95 out of 5 average rating, 21 reviews

Modern House in Altos de Cerro Azul with 2 rooms

This stunning home offers an unparalleled combination of modern luxury and natural beauty, making it the perfect spot for those looking for a serene mountain getaway. Enjoy an open concept space that integrates seamlessly with the surrounding landscape. Air Conditioned Rooms Flexible check-in and check-out hours. Grill

Jun 29 – Jul 6

ﺩ.ﺇ493 per night