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Apartment vacation rentals in Rochester

Find and book unique apartments on Airbnb

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Popular amenities for Rochester apartment rentals

Weekly apartment rentals

Superhost
A comfortable living area features a large sectional sofa with decorative pillows. A glass coffee table is centered on a soft area rug. A workspace with a desk and chair is present, along with wall art and a lamp providing ambient light.
Apartment in Rochester
4.77 out of 5 average rating, 226 reviews

Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo

Anthony & NancyRating, 5 stars3 weeks ago
This was our third stay at Terri and Brett’s. Each time, it has been in a different apartment. Getting in is easy. If you have to do laundry, it’s right there. The WiFi is the best of the three apartments. The apartment is cozy and inviting. You are 2 1/2 blocks from the Mayo subway where you can find one of the healthiest Mayo cafeterias in the Dan Abraham Healthy Living Center. While the healthy living center is for Mayo employees, the cafeteria is open to anyone. A couple of blocks away is Kutzy Park, which provides a nice, secluded walk. A short drive away are Hy-Vee, Nupa North, a no frills Mediterranean restaurant, and Forager, a locally sourced restaurant, that are consistently recommended by locals.
Guest favorite
A modern living area features large windows allowing natural light to fill the space, showcasing views of the outdoors. Two plush sofas face a sleek coffee table and a mounted television, enhancing the open and airy atmosphere.
Apartment in Rochester
4.92 out of 5 average rating, 25 reviews

Stunning Urban Loft with 30ft Windows – Near Mayo

IngridRating, 5 stars2 weeks ago
Beautiful unit in a great location. Easy walk to Mayo and downtown. Very clean and well stocked. Communication was exceptional. Thanks for a great stay!
Guest favorite
The living area features a spacious gray sofa and a coordinating armchair, positioned around a circular wooden coffee table. A flat-screen TV is mounted on the wall. Natural light streams through sliding glass doors that lead to a private balcony, enhancing the inviting atmosphere.
Apartment in Rochester
4.91 out of 5 average rating, 23 reviews

Spacious Apartment Near Mayo Clinic – Free Parking

NanRating, 5 stars5 months ago
Great location if you are visiting Mayo. Walkable distance from the hospital and also a supermarket within walkable distance. The room is spacious and the sofa in the living room opens up to two beds if needed. Host is extremely quick to reply on any messages. The building management team is also very helpful. I had an amazing time there!
Superhost
A cozy den area features a brown sofa with a light blue throw blanket and decorative pillows. A small table is positioned nearby, accompanied by a lamp. Natural light filters through sheer curtains, illuminating the wood-paneled walls and a patterned area rug.
Apartment in Rochester
4.86 out of 5 average rating, 88 reviews

Large 1 BR in 4plex, 1 mile from Mayo.

JacquelineRating, 5 stars5 months ago
Nice apartment and hosts were very responsive and helpful!
Guest favorite
The entrance to Nicholas Apartments is marked by a welcoming archway. Lush greenery and neatly manicured lawns surround the pathway, which leads to the inviting brick building featuring multiple balconies and large windows.
Apartment in Rochester
4.92 out of 5 average rating, 13 reviews

Free Parking, New Apartment, Steps From Mayo!

MarionRating, 5 stars1 week ago
I would definitely stay again. Really cozy and comfortable stay. Beautiful location and everything was very easy. Very clean and tidy and up to date. Highly recommend.
Superhost
A well-appointed living area is highlighted by a brown couch adorned with decorative pillows. A mid-century modern coffee table is center stage on a patterned rug. Natural light fills the space through two large windows, and a blue accent chair adds a pop of color.
Apartment in Rochester
4.86 out of 5 average rating, 29 reviews

Fresh space near Mayo Clinic and downtown

HawraRating, 5 stars10 months ago
We recently completed a 3 month stay at this Airbnb, and it truly felt like a home away from home. The place was clean and decorated in a lovely, modern style. It felt fresh and new, which made a big difference for such a long stay. One of the biggest perks was the location. It was incredibly convenient, with close proximity to almost everything we needed. Most importantly for us, it was super close to the Mayo Clinic, which we had to visit frequently for appointments. The river was just a block away, which provided a lovely spot to walk and fresh air. Kris and Doug were fantastic hosts. They were incredibly responsive and attentive to our needs. Whenever a minor issue arose, the host came right away to fix it. It was clear they cared about our comfort throughout our stay. The Airbnb itself was well-equipped with all the gadgets and appliances we needed for an extended stay. We were able to cook meals easily and felt comfortable settling in for the long term. Highly recommended.
Guest favorite
The living area features a large, comfortable sofa with plush cushions, positioned around a coffee table. A flat-screen TV is mounted on the wall opposite the seating, while the kitchen area is in view with modern appliances, including a refrigerator and stove.
Apartment in Rochester
4.94 out of 5 average rating, 53 reviews

Spacious 2 bedroom 2 bath Apartment Steps from May

JaimieRating, 5 stars1 month ago
This was comfortable, clean, modern, and easy to access/directions! Would stay here again!
Superhost
A living area is presented with a beige sofa adorned with decorative pillows. Glass side tables are placed beside the sofa, and two lamps provide soft lighting. A circular dining table with black, metal chairs is positioned nearby, alongside a colorful area rug.
Apartment in Rochester
4.73 out of 5 average rating, 153 reviews

Relaxing, main floor apartment in 4plex, #2.

RachelRating, 5 stars1 week ago
They were super responsive and accommodating for what I needed for check in and check out due to my appointments at Mayo and coming from MI.

Private apartment rentals

Superhost
The living area is furnished with a brown sofa and a black chair, complemented by a small round table. A kitchen can be seen in the background, equipped with modern appliances. A light-colored rug lies on the floor, enhancing the space's comfort.
Apartment in Rochester
5 out of 5 average rating, 3 reviews

Cozy Nook | Right Across From St Marys!+Parking

SusanRating, 5 stars6 months ago
While here at Mayo it was a perfect location for me as it was close to the clinic. The apartment was quiet and peaceful. If I had to give a downfall it would only be that the parking, getting to the actual apartment could use a walkway of sorts as it's gravel (rocks). Would stay again. Host was great. Highly recommend.
The living area features a comfortable gray sofa adorned with decorative pillows and a stylish throw. A wooden coffee table sits on a patterned area rug, accented by a modern lamp. The backdrop includes a kitchen area with wooden cabinetry, visible in soft light.
Apartment in Rochester
4.68 out of 5 average rating, 47 reviews

♢ Mayo in 2 Blocks ♢NO STEPS/Elevator❥Private Code

SusanRating, 5 stars2 months ago
The location is very convenient if you’re visiting Rochester for appointments at Mayo Clinic. It was a short walk to my appointments at the Gonda Building and there are many restaurants within walking distance too. Jackie was extremely helpful and responsive.
A cozy living area features a light sofa draped with a throw, complemented by a glass coffee table. Natural light floods the space through sliding glass doors, which open to a patio area. A television sits on a wooden console, and a small tree adds greenery.
Apartment in Rochester
4.75 out of 5 average rating, 4 reviews

Luxury 1 bedroom Serenity

AdelRating, 5 stars6 months ago
Brand new place with a piece of mind location. Very quiet, green areas, and sidewalks around the property. Great clubhouse, gym, and amenities. Host was very friendly, responsive, and accommodating. On-site team was just as good. Highly recommend it for those who want stay in calming place while getting things done in town or Mayo Clinic.
A bright dining area is highlighted by large, arched windows with soft fabric curtains. A small white table is accompanied by two yellow chairs, offering a cheerful spot for meals, with views of the surrounding neighborhood visible through the window.
Apartment in Rochester
4.67 out of 5 average rating, 108 reviews

A Pet friendly, bright and warm, Private apartment

LeahRating, 5 stars2 weeks ago
Very close to the Mayo campus and hospital. Elizabeth was proactive with her communication, very friendly and gave very clear instructions on parking and how to get into the house.
A cozy living area is highlighted by a light-colored sofa and a brown armchair. Natural light enters through a window, illuminating a rug with intricate patterns laid on the floor. A piece of artwork is displayed on the wall, complementing the calming green tones.
Apartment in Hammond
4.71 out of 5 average rating, 14 reviews

Zumbro Valley Getaway

EmmelineRating, 5 stars2 weeks ago
We were in the area for a 50 mile race my husband was running and brought along the whole family. The hosts were friendly, thorough and very accommodating. When they heard that a toddler and a baby would be staying they asked us how we could make their space safer for my sons and that meant a lot to me. They even left out a little veggie cutting play set that my 2 year old played with all weekend. They just really went above and beyond to make us feel comfortable and welcome. I would certainly stay here again!
Guest favorite
A living area features comfortable seating with a recliner and a neutral-toned couch. Light streams through sheer curtains, illuminating a decorative coffee table on an area rug. A desk with a lamp is positioned against the wall, providing a functional workspace.
Apartment in Rochester
4.81 out of 5 average rating, 21 reviews

5-Star 5 Mins to Mayo 2 Bedroom Discounted Duplex!

RickRating, 5 stars1 month ago
We stayed here because one of us had surgery at Mayo, so we didn't do things around town or use the walking trail, etc. Things we really liked in the rental: memory foam toppers on the beds made them super comfortable; plentiful outlets and USB ports that were easily accessible; well-stocked kitchen; comfortable double recliners; and a lift recliner that was a godsend after surgery. John was very responsive with a couple of issues, and was easy to communicate with. I'd highly recommend this rental.
Guest favorite
A welcoming living area features a blue sofa adorned with colorful pillows in various patterns. An abstract artwork hangs above, complementing the space. Soft, natural light enters through the large windows, which are dressed with sheer curtains, enhancing the cozy ambiance.
Apartment in Rochester
5 out of 5 average rating, 12 reviews

Penthouse Suite—Steps from Mayo Clinic Hospital

KimberlyRating, 5 stars2 months ago
We stayed in the Penthouse apartment, and it was perfect for our week of appointments at Mayo Clinic. We walked to/from appointments at the Mayo/Gonda buildings as well as to local restaurants and parks.
The bedroom features a dark wooden bed with layered bedding and a decorative cushion. A matching armchair sits in the corner, and a lamp is placed on a bedside table. The window is covered with a golden curtain, allowing for natural light.
Apartment in Rochester
4.7 out of 5 average rating, 10 reviews

Cozy 1 Bed 1 Bath apartment - walk to Mayo

SherenaiRating, 5 stars7 months ago
Had a wonderful stay! Clean, cozy and private. I was in town for 3 weeks while transitioning to a new job and the fact that I had a nice place to return to each day was such a relief. Great host, very responsive and he gave clear instructions on how to get in and out.

Family-friendly apartment rentals

A cozy living area features a red upholstered sofa accompanied by a glass coffee table. Natural light filters through the adjacent windows, which are dressed with sheer curtains. A dining table with elegant chairs sits nearby, set with decorative dishware and a small centerpiece.
Apartment in Alma
4.67 out of 5 average rating, 24 reviews

Swan Suite River front comfort

ElizabethRating, 5 stars55 months ago
Hotel De Ville is a delightful home away from home. If you’re visiting the Alma, Wisconsin or the Buffalo County area and you need to making lodging arrangements this is the place to stay. Our suite was charming and comfortable. Daniel says he’s fastidious about cleanliness and he means it. Our rental was clean, and any worries about COVID-19 and proper sanitizing were rapidly dispelled after entering our suite. Daniel gave us great tips on eating establishments as well as the Castle Rock Museum and other points of interest.
A cozy living area is highlighted by floral wallpaper and a vintage patterned sofa. A wooden bookshelf contains books and decorative items, while a table lamp adds soft lighting. A suit of armor stands nearby, and a doorway leads into a formal dining area.
Apartment in Alma
4.92 out of 5 average rating, 12 reviews

Fountain Suite Apartment

AlexandraRating, 5 stars46 months ago
Super cute Airbnb! We really loved it! The garden was great, the beds comfortable, the location amazing!
Guest favorite
A bright kitchen area features modern appliances including a black stove and a white refrigerator. A dark wooden dining table is positioned centrally, surrounded by chairs. Natural light enters through sliding glass doors that open to a small outdoor space, enhancing the room's airy feel.
Apartment in Rochester
4.92 out of 5 average rating, 91 reviews

Beautiful Duplex home 5 minute walk to Mayo Clinic

KristinaRating, 5 stars14 months ago
Very welcoming. Close to Mayo. Nice for a stay at Mayo Clinic.
Apartment in Rochester
4.8 out of 5 average rating, 192 reviews

EXCEPTIONAL, CONTEMPORARY 2BD/1 BA/ CLOSE TO MAYO

MikeRating, 5 stars3 weeks ago
Everything was really nice. Perfect location close to the National Volleyball Center. Only gripe was the bathroom was not fully renovated, floor tile was incomplete and shower tile was just painted over.
A spacious living area features a checkered sofa adorned with two red pillows. Light wood flooring complements the warm tones of the walls. Arched doorways lead to adjacent rooms, enhancing the open feel of the space. A ceiling fan is present for added comfort.
Apartment in Blooming Prairie
4.91 out of 5 average rating, 221 reviews

Restful space for your momentary place in BP

AndreaRating, 5 stars5 months ago
We stayed at Eaton's place again for one quick overnight stay. Everything was great! Eaton is friendly and responsive. We'll stay again in the future!
A cozy living area features floral wallpaper and soft lighting. A wooden table is surrounded by vintage chairs, while a lamp provides additional illumination. Fresh flowers adorn a side table, and a doorway reveals a bedroom beyond, contributing to a warm and welcoming ambiance.
Apartment in Alma
4.88 out of 5 average rating, 40 reviews

Garden Suite River View in Elegance

WendyRating, 5 stars18 months ago
We enjoyed our stay in Alma. Daniel was very friendly and showed us how to lock the door. The apartment would benefit from a deep clean, but it was reasonably clean. There was no lightbulb in one of the lamps, but it was otherwise exactly as described. And the shower? Excellent. Great pressure and really nice shampoo and shower gel. Alma is a beautiful town - we enjoyed exploring the area. Thank you!
Guest favorite
The living area features large windows allowing natural light to illuminate the space. A comfortable sofa and chairs are arranged around a coffee table on a patterned rug. A lamp and a small desk add functionality, while a television is mounted on the wall.
Apartment in Rochester
4.89 out of 5 average rating, 89 reviews

Rochester Home (Duplex) 5 min walk to Mayo

ConnieRating, 5 stars2 weeks ago
Location was a comfortable walk to Mayo for appointments. Jordan responded quickly to concerns. Nice, comfortable accommodation!

Quick stats about apartment rentals in Rochester

  • Total rentals

    170 properties

  • Nightly prices starting at

    ﺩ.ﺇ73 before taxes and fees

  • Total number of reviews

    7.2K reviews

  • Family-friendly rentals

    60 properties are a good fit for families

  • Pet-friendly rentals

    60 properties allow pets

  • Rentals with dedicated workspaces

    110 properties have a dedicated workspace

Destinations to explore