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Vacation rentals in Rio Sereno

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Rio Sereno

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in San Vito
5.0 out of 5 average rating, 11 reviews

Private 40-Acre Hacienda Estate

Our Hacienda sits on 40 Acres of land that was once one of the areas original Coffee plantations. Today, it is a private Estate with big jungle trees, about 4km of trails, fruit orchards and beautiful gardens. The house has been fully renovated and is welcoming and comfortable. A large wrap-around terrace looks out toward Volcán Barú and La Amistad Park. Hacienda Viva offers a setting to slow down and reconnect. Our place offers something for everyone..a perfect place to enjoy and make Memories!

FamilyLocationQuiet

Top guest favorite
A private jacuzzi is visible, with water gently bubbling in a serene setting. Surrounding trees provide shade and a sense of privacy. The distant mountains create a tranquil backdrop, while a wooden deck and seating area are positioned nearby, enhancing the outdoor experience.
Home in Boquete
5.0 out of 5 average rating, 14 reviews

Catuai Casita @ Finca Panda

Catuai is one of our luxury casitas at Finca Panda in Boquete. Designed for the traveler wanting comfort, peace and privacy while still close to all of Boquete's amazing restaurants and activites. All details are on our website, but here are a few amenities - private jacuzzi, gas fire pit, walkout shower, full kitchen, washer/dryer, breakfast included, daily cleaning included, high-speed wifi, Netflix and much more. Perfect for couples, friends or families looking for the best in Boquete.

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Top guest favorite
A covered terrace features wooden rocking chairs, providing a relaxing space with views of lush gardens and mountains in the background. A small table holds a laptop and a plate of fresh fruit, inviting a peaceful atmosphere for work or leisure.
Bungalow
4.97 out of 5 average rating, 192 reviews

Romantic getaway A birdwatchers paradise

Very modern and spacious. Room includes its own terrace with private entrance ! Beautiful view of pond with Baru Volcano as background. The perfect place to enjoy your morning cup of coffee listening to birds. You have your own private fridge,stove top, a small counter top oven , microwave and coffee maker in your suite! Plus all the basics ( coffee, salt, pepper, olive oil , etc), pots and pans. Come enjoy and relax in this so romantic place! We also have high speed internet !

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Top guest favorite
Cave in Cuesta de Piedra
4.86 out of 5 average rating, 14 reviews

Cave in the Air A spectacular view of the Baru

IDEAL for couples looking for a romantic getaway, travelers who want to disconnect from stress, mountain lovers seeking inspiration and rest, as well as photographers, content creators and those who enjoy unique experiences. Located between Volcán and Boquete, a refuge INSPIRED by the air, surrounded by glass, volcanic stones, and abundant vegetation. Interior with a privileged view of the Barú Volcano. Its exclusive basalt bathroom is made of volcanic stones,

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Guest favorite
Home in Volcan
4.96 out of 5 average rating, 24 reviews

Comfortable stay at Casa La Perla.

The perfect getaway for your vacation just minutes from downtown Volcán. Here you will feel at home, while enjoying a delicious climate and beautiful landscapes overlooking the impressive Barú Volcano. Casa La Perla offers a space with all the necessary amenities for a pleasant stay: spacious and comfortable beds, equipped kitchen, bathroom with hot water, internet service, television, security and terrace with hammock. Don't miss this charming experience.

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Top guest favorite
Loft in Coto Brus
4.97 out of 5 average rating, 31 reviews

Ecoluma 1: Cozy studio with garden in Sabalito

Welcome to our charming studio in Sabalito de Coto Brus. This space offers the perfect combination of natural tranquility and the convenience of being close to downtown. In addition, we are 10 minutes from the border of La Unión and Río Sereno, 1 hour from Paso Canoas and 1.30 hours from the Golfito Free Warehouse. Ideal for couples, solo travelers, or professionals looking for a quiet retreat in the Coto Brus area. We have an e-invoice.

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Guest favorite
Cabin in Paraiso
4.88 out of 5 average rating, 42 reviews

Best alpine cabin with jacuzzi and amazing weather

Alpine cabin located between Boquete and Volcán. Set in a very peaceful area and fully equipped so you can enjoy an amazing vacation. It features a terrace and a balcony with views of Volcán Barú and the ocean. It also has a hot-water jacuzzi so you can take relaxation to the next level. Paraíso is known for its excellent climate, rivers, lush vegetation, canopy tours, and hiking trails so you can make the most of your stay.

FamilyValueOutdoor spaces

Superhost
The modern structure features distinct angular roofs and large glass doors, providing a clear view of the interior. Soft lighting highlights the building's exterior against a twilight sky, enhancing the serene environment surrounded by neatly arranged landscaping.
Cabin in Sabalito
5.0 out of 5 average rating, 5 reviews

Barrantes Accommodation.

This trendy spot offers lots of charming details. It is located near downtown Sabalito, just 10 minutes from the Rio Sereno Panama border crossing. Located in a quiet and safe place, with optimal facilities to rest properly and with a pleasant climate. If you are a person who enjoys exercising, just 500 meters away you can find an athletics track, as well as a beach soccer field and beach volleyball.

Check-inSleep qualityComfort

Guest favorite
Home in Renacimiento
5.0 out of 5 average rating, 5 reviews

Casa Mariposa Full Accommodation

Relax with the whole family in this quiet place surrounded by nature, located just 5 minutes from the Rio Sereno sector border, fully equipped, you will wake up with the birdsong. We have taken care of every detail to make you feel at home. From our accommodation you can enjoy all the natural beauties of Coto Brus and its surroundings. Your pets are welcome, fully enclosed property for added privacy.

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Guest favorite
Cabin in Boquete
4.92 out of 5 average rating, 26 reviews

Cabin in Alto Boquete 2

Welcome to Cabañas Piedra del Risco. Our cabanas were designed to offer the perfect balance between modern and rural. From the terrace you will see the majestic Volcán Barú and the canyon of the Caldera river, you will be surrounded by nature and the unique tranquility of Boquete. We are just 12 minutes from downtown Boquete, close enough to explore, and far enough to disconnect.

LocationFamilyRiver

Guest favorite
A spacious room features a wooden bed with a crisp white quilt. Two chairs with bright yellow cushions are placed beside a low wooden table. Natural light filters through the windows, and an abstract painting adds a splash of color to the wall.
Cabin in Canoas
4.94 out of 5 average rating, 139 reviews

Guayacán Cabin

Cozy cabins that will make your stay in Paso Canoas pleasant. Excellent for shopping as they are 2km from the Paso Canoas free zone, in front of the Inter-American highway. Pet-friendly, we have some dogs. If you visit us with pets, you must pay at check-in $20 / ¢10,000 for the first night of the pets' stay and $10 / ¢5000 for each extra night.

ValueFamilyGetting around

Guest favorite
A vibrant blue cabin is nestled among lush tropical plants, surrounded by tall palms and dense greenery. The elevated structure features a deck with chairs, offering an inviting outdoor space while maintaining privacy within the natural landscape.
Cabin in Zancudo
4.81 out of 5 average rating, 72 reviews

Stunning beach front cabin w/ wifi

Our cabin, called the Resting Dragon, has 250 feet (75 meters) of beach front property, offering gorgeous views and complete privacy. Perfect for a relaxing vacation with all amenities available: full kitchen, living room, queen bed and sofa bed, large deck and 10mbs high speed internet to facilitate teleworking and video conference calls.

LocationValueIndoor spaces

Popular amenities for Rio Sereno vacation rentals