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Vacation rentals in Rio Sereno

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Rio Sereno

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in San Vito
5 out of 5 average rating, 11 reviews

Private 40-Acre Hacienda Estate

Our Hacienda sits on 40 Acres of land that was once one of the areas original Coffee plantations. Today, it is a private Estate with big jungle trees, about 4km of trails, fruit orchards and beautiful gardens. The house has been fully renovated and is welcoming and comfortable. A large wrap-around terrace looks out toward Volcán Barú and La Amistad Park. Hacienda Viva offers a setting to slow down and reconnect. Our place offers something for everyone..a perfect place to enjoy and make Memories!

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Top guest favorite
A covered terrace features wooden rocking chairs, providing a relaxing space with views of lush gardens and mountains in the background. A small table holds a laptop and a plate of fresh fruit, inviting a peaceful atmosphere for work or leisure.
Bungalow in Provincia de Chiriquí
4.97 out of 5 average rating, 193 reviews

Romantic getaway A birdwatchers paradise

Very modern and spacious. Room includes its own terrace with private entrance ! Beautiful view of pond with Baru Volcano as background. The perfect place to enjoy your morning cup of coffee listening to birds. You have your own private fridge,stove top, a small counter top oven , microwave and coffee maker in your suite! Plus all the basics ( coffee, salt, pepper, olive oil , etc), pots and pans. Come enjoy and relax in this so romantic place! We also have high speed internet !

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Guest favorite
Home in Golfito
5 out of 5 average rating, 6 reviews

New! Romantic-Private-Incredible views-Luxury

Most luxurious one bedroom home in Golfito Completed May 2026 Escape to a private modern villa surrounded by lush jungle with beautiful Gulf views. This secluded retreat features a large private pool, spacious indoor-outdoor living, and a fully equipped kitchen. Floor-to-ceiling windows bring nature inside, while AC, high-speed internet, and a large TV provide comfort. Perfect for couples seeking privacy, wildlife, and easy access to Golfito, Corcovado, and nearby beaches.

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Top guest favorite
Loft in Coto Brus
4.97 out of 5 average rating, 31 reviews

Ecoluma 1: Cozy studio with garden in Sabalito

Bienvenidos a nuestro encantador estudio en Sabalito de Coto Brus. Este espacio ofrece la combinación perfecta entre la tranquilidad natural y la conveniencia de estar cerca del centro del pueblo. Además, estamos a 10 min de la frontera de La Unión y Río Sereno, a 1hr de Paso Canoas y 1.30hrs del Depósito Libre Golfito. Ideal para parejas, viajeros en solitario o profesionales que buscan un retiro tranquilo en la zona de Coto Brus. Contamos con factura electrónica.

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Guest favorite
A modern two-story house is displayed with a light-colored exterior and a red roof. Large windows are seen throughout, enhancing natural light inside. A gravel pathway leads to the entrance, bordered by lush greenery and flowering plants, providing a serene and inviting approach.
Home in Agua Buena
4.95 out of 5 average rating, 22 reviews

Casa Arzú San Vito Coto Brus

Located 1:00 from Paso Canoas Casa ARZÚ located in Santa Cecilia de Agua Buena, Coto Brus. It is a place full of peace, surrounded by nature, great views, including towards the Barú Volcano and surrounding communities. Cool weather. It is spacious, private, and has all the necessary amenities for a pleasant and satisfying stay. Ideal for disconnecting from the daily grind. To enjoy these beautiful views, you will have to walk about 7 minutes on the lastre road.

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Top guest favorite
Cave in Cuesta de Piedra
4.86 out of 5 average rating, 14 reviews

Cave in the Air Panoramic view of the Barú

IDEAL for couples looking for a romantic getaway, travelers who want to disconnect from stress, mountain lovers seeking inspiration and rest, as well as photographers, content creators and those who enjoy unique experiences. Located between Volcán and Boquete, a refuge INSPIRED by the air, surrounded by glass, volcanic stones, and abundant vegetation. Interior with a privileged view of the Barú Volcano. Its exclusive basalt bathroom is made of volcanic stones,

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Guest favorite
Cabin in Paraíso
4.88 out of 5 average rating, 42 reviews

Best alpine cabin with jacuzzi and amazing weather

Alpine cabin located between Boquete and Volcán. Set in a very peaceful area and fully equipped so you can enjoy an amazing vacation. It features a terrace and a balcony with views of Volcán Barú and the ocean. It also has a hot-water jacuzzi so you can take relaxation to the next level. Paraíso is known for its excellent climate, rivers, lush vegetation, canopy tours, and hiking trails so you can make the most of your stay.

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Top guest favorite
A private deck features two modern chairs with a small table between them, positioned on a textured area rug. A custom-built jacuzzi is visible in the background, surrounded by a wooden railing. Natural light floods the indoor living area through expansive glass doors.
Cabin in Boquete
5 out of 5 average rating, 11 reviews

New World Casita @ Finca Panda

Mundo Novo is one of our new, one-room casitas and has one of the most incredible views on the property. Perfect for couples, singles or family with a small child, Geisha sleeps 2 people comfortably in one king bed (maximum 3 guests when using sofa). Geisha was designed with every amenity needed to have a perfect and relaxing stay. Custom-built jacuzzi, fire-pit, kitchen, incredible shower, high-speed WiFi and more

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Guest favorite
Home in Renacimiento
5 out of 5 average rating, 5 reviews

Casa Mariposa Full Accommodation

Relax with the whole family in this quiet place surrounded by nature, located just 5 minutes from the Rio Sereno sector border, fully equipped, you will wake up with the birdsong. We have taken care of every detail to make you feel at home. From our accommodation you can enjoy all the natural beauties of Coto Brus and its surroundings. Your pets are welcome, fully enclosed property for added privacy.

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Guest favorite
Cabin in Boquete
4.93 out of 5 average rating, 27 reviews

Cabin in Alto Boquete 2

Welcome to Cabañas Piedra del Risco. Our cabanas were designed to offer the perfect balance between modern and rural. From the terrace you will see the majestic Volcán Barú and the canyon of the Caldera river, you will be surrounded by nature and the unique tranquility of Boquete. We are just 12 minutes from downtown Boquete, close enough to explore, and far enough to disconnect.

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Guest favorite
A spacious room features a wooden bed with a crisp white quilt. Two chairs with bright yellow cushions are placed beside a low wooden table. Natural light filters through the windows, and an abstract painting adds a splash of color to the wall.
Cabin in Paso Canoas
4.94 out of 5 average rating, 139 reviews

Guayacán Cabin

Cozy cabins that will make your stay in Paso Canoas pleasant. Excellent for shopping as they are 2km from the Paso Canoas free zone, in front of the Inter-American highway. Pet-friendly, we have some dogs. If you visit us with pets, you must pay at check-in $20 / ¢10,000 for the first night of the pets' stay and $10 / ¢5000 for each extra night.

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Top guest favorite
Two spacious beds are positioned in a well-lit room featuring a sleek, dark accent wall. Soft lighting highlights the beds, which are neatly made with minimalist bedding. Polished floors reflect the light, creating a clean and modern environment.
Home in San Vito
5 out of 5 average rating, 24 reviews

Casa Catalana

Your family will be close to everything when you stay in this centrally located accommodation less than 3 minutes from San Vito. The house is located in a very quiet family neighborhood with beautiful mountain views. The property is visited by beautiful birds and animals every day.

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Popular amenities for Rio Sereno vacation rentals