Vacation rentals in Potrero Grande

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Potrero Grande

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

Home in Playa Costa Esmeralda

4.98 out of 5 average rating, 219 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

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Top guest favorite

Place to stay in Panama City

5.0 out of 5 average rating, 24 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

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Top guest favorite

An outdoor space features a heated pool surrounded by light-colored tiles. A covered patio includes modern seating arrangements and a table, suitable for dining. Lush greenery is visible beyond the walls, with a glimpse of the sky above, providing a bright and open feel to the area.

Home in Vacamonte

5.0 out of 5 average rating, 46 reviews

The Hidden Gem

Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

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Guest favorite

The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.

Home in Altos del María

4.82 out of 5 average rating, 332 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

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Guest favorite

Villa in Punta Chame

4.97 out of 5 average rating, 151 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

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Guest favorite

Home in Altos del María

4.77 out of 5 average rating, 163 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

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Guest favorite

A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.

Guesthouse in Panamá Oeste

4.84 out of 5 average rating, 159 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

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Superhost

The villa's modern exterior is illuminated at night, showcasing a sleek facade with clean lines. Lush landscaping with palm trees frames the entrance. A vehicle is parked in front, highlighting the spacious driveway. The large front steps lead to the welcoming double doors.

Home in Veracruz

4.94 out of 5 average rating, 31 reviews

Luxury beachfront villa!

Discover luxury in our new oceanfront villa in Veracruz Chumical, just 30 minutes from Panama City. With 5 bedrooms, 6 bathrooms, 5 king beds and 2 double cabins, it is ideal for families and friends. Relax in the infinity pool with spectacular views or enjoy the equipped kitchen, spacious living room and barbecue area. Take in the illuminated ships on the rooftop and enjoy a unique experience. Book now and enjoy being the first in our beautiful Villa!

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Guest favorite

Cabin in Panama City

4.93 out of 5 average rating, 92 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

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Top guest favorite

A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.

Home in Distrito Arraijan

4.98 out of 5 average rating, 233 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

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Guest favorite

Home in Gamboa

4.86 out of 5 average rating, 111 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

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Top guest favorite

A modern apartment building is presented, featuring a well-maintained pool area in the foreground. Multiple lounge chairs and tables are arranged neatly around the pool, which reflects the blue sky above. The building showcases large windows, enhancing natural light throughout its levels.

Apartment in La Chorrera

4.93 out of 5 average rating, 54 reviews

The best getaway place in Panama

Enjoy the charmed Panama from our beautiful apartment in Costa Verde, La Chorrera. 30 minutes away from Panama City and 30 minutes away from tipical Panama provinces. Walk distance to the mall, banks, restaurants, pharmacies, stores and much more. Perfect place for you to enjoy all places of Panama. Relax with the whole family at this peaceful place to stay.

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