House vacation rentals in Panhandle

Find and book unique houses on Airbnb

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Popular amenities for Panhandle house rentals

House rentals with a pool

Guest favorite
Home in Amarillo
4.96 out of 5 average rating, 114 reviews

Private indoor mineral pool & spa retreat house

LauraRating, 5 stars1 week ago
This is a beautiful, cozy, and relaxing home. The spa room is amazing! The pool is not heated but still easy to adjust to the temperature of the water once you get in. The hot tub was so relaxing. It was nice to be able to have a movie night while in the hot tub! The kitchen is very spacious and well equipped with dishes, utensils, and appliances. The rooms were very cozy. Beds were comfortable. We had a couple of non-essential things that needed maintenance. They were repaired within a timely manner. I would definitely recommend this home. It would be an awesome sisters or couples getaway.
Top guest favorite
Home in Amarillo
5 out of 5 average rating, 27 reviews

Private Pool + Park Across Street

ElaineRating, 5 stars1 week ago
Loved the house, plenty of room, fully stocked with pots and pans and everything we needed plus plenty of towels. The pool was great with lots of pool toys. The kids loved it.
Guest favorite
Home in Amarillo
4.94 out of 5 average rating, 243 reviews

McKinley House Prime - Pool * Patio * Garage

ChaseRating, 5 stars1 week ago
We loved our stay. The back patio is very relaxing and we enjoyed the pool. It’s always nice to have a garage to park in as well. The house was very clean and had everything we needed. The beds were very comfortable as well. We will definitely be back.
Superhost
Home in Amarillo
4.78 out of 5 average rating, 18 reviews

Panhandle Hideaway

JulianRating, 5 stars2 weeks ago
Thank you, Mat, for a wonderful stay! The place was clean, comfortable, and exactly as described, great communication, would definitely stay again!
Guest favorite
Home in Clarendon
5 out of 5 average rating, 8 reviews

Parkside Retreat

MarcieRating, 5 stars8 months ago
We had a wonderful stay! The home was very nice and had a beautiful outdoor area in the backyard. The kitchen was stocked with lots that made it easy to eat in. Lots of room to spread out!
Home in Amarillo
5 out of 5 average rating, 4 reviews

Holyoke Haven

DarsyRating, 5 stars2 months ago
Vanessa was a wonderful host. Beautiful and welcoming home. Definitely recommend this Airbnb. We look forward to future stays.
Home in Pampa

Home with office and Wi-fi

IsaiahRating, 5 stars3 months ago
The house is just as good as the listing shows. I really enjoyed the homey vibes it gave. The backyard is great for hanging out, grilling and eventually swimming. The host were great and always responsive when something was needed or more information was needed! Definitely plan on being back!
Guest favorite
Home in Amarillo
4.85 out of 5 average rating, 27 reviews

Friends & Family Fresno House

CheriRating, 5 stars2 weeks ago
Jacky‘s place was exactly what we wanted for our sister’s weekend getaway. The expansive outdoor living area was where we parked it… Cooking, dining, lounging, floating in the pool. It’s like a resort!

Weekly house rentals

Top guest favorite
Home in Panhandle
5 out of 5 average rating, 37 reviews

Mellow out on Main

Chris & LacieRating, 5 stars1 week ago
Mellow out on Main was a beautiful place to stay! It was easy to find, very clean, and has a cute, charming vibe. The house is also very spacious and we enjoyed playing pool as well!
Top guest favorite
Home in Amarillo
4.93 out of 5 average rating, 137 reviews

*Close to Restaurants, Shopping, Medical, Theater*

MatthewRating, 5 stars1 week ago
Very nice neighborhood and large enough home for our family of 8 comfortably great location close to parks restaurants and discovery science center in Amarillo
Guest favorite
Home in Canyon
4.83 out of 5 average rating, 194 reviews

Peaceful Valley

MelanieRating, 5 stars1 week ago
We had a great stay and were very thankful for the carport (due to some storms / hail that came through). Highly recommend!
Top guest favorite
Home in Amarillo
4.99 out of 5 average rating, 134 reviews

The Crystal Dragonfly

MichaelRating, 5 stars1 week ago
Mary's home was great! It was as described and she was very responsive and easy to communicate with. We will stay again !
Superhost
Home in Amarillo
4.87 out of 5 average rating, 488 reviews

5 Bedroom/2 Bath, Gameroom + Firepit- Haven House

CharlesRating, 5 stars1 week ago
It was a great place. My family and I made a trip to Sequoia National Park. This place was amazing. We only had one bad Air b and b on the whole trip. The night before we stayed in a basement with no air conditioning in Flagstaff Arizona so that made this place even better.
Guest favorite
Home in Borger
4.88 out of 5 average rating, 49 reviews

Big Davis

RachelRating, 5 stars1 month ago
Michelle was extremely responsive and kind. So hospitable to myself and my family here for a graduation. The house had a great backyard, plenty of towels and linens and felt cozy!
Guest favorite
Home in Borger
4.92 out of 5 average rating, 24 reviews

Davenport

DaleRating, 5 stars1 month ago
We {two couples} really liked this property and hopefully it will be available on our next visit. This trip was adults only but we would have no issues having the grandkids along. Nice big rooms and plenty of space to spread out. Pictures and amenities were spot on. We did not have time to utilize the outdoor space but it was more than ample for a family cookout and the huge covered patio is a plus.The beds were comfortable and the kitchen well stocked. Detail to cleaning did not go unnoticed. Communication was fast and friendly,check in was super easy. It's a keeper on our list.
Guest favorite
Home in Canyon
4.9 out of 5 average rating, 179 reviews

Greener Pastures with large covered patio

Mike & DianaRating, 5 stars1 week ago
Jessica was very responsive and helpful. The beds were so comfortable!

Private house rentals

Top guest favorite
Home in Canyon
4.95 out of 5 average rating, 44 reviews

Cozy Cabin by WTAMU- Gateway to Palo Duro Canyon

Maureen Rating, 5 stars4 days ago
Perfect place to stay after our visit to Palo Duro Canyon- comfy and cozy.
Top guest favorite
Home in Canyon
4.98 out of 5 average rating, 53 reviews

Chateau Bliss: Stylish Stay w/ HOT TUB

SamanthaRating, 5 stars5 days ago
We had a great stay here! Everything was how it looked in the photos and in a great neighborhood! Would definitely stay here again!
Top guest favorite
Home in Pampa
5 out of 5 average rating, 11 reviews

Very centrally located

JoshuaRating, 5 stars1 month ago
House was great and clean
Guest favorite
Home in Amarillo
4.87 out of 5 average rating, 53 reviews

Amarillo By Morning (I-27/I-40)

JenniferRating, 5 stars4 days ago
Great location, easy to get to off the I-40. We had a budget truck pulling a car trailer and it fit just perfectly along the street! Dog friendly and super responsive host
Guest favorite
Home in Amarillo
4.96 out of 5 average rating, 76 reviews

Cozy Corner on Lazy B

PriRating, 5 stars3 weeks ago
Perfect little house and very well maintained
Guest favorite
Home in Amarillo
4.9 out of 5 average rating, 72 reviews

Historical Downtown Beauty. Clean and charming!

YolandaRating, 5 stars1 month ago
Loved the location. Was very convenient for all the activities we had planned. The house is beautiful and well kept. Felt right at home. Marcus communicated very well. Fast and friendly. we enjoyed our stay very much
Guest favorite
Home in Amarillo
4.91 out of 5 average rating, 45 reviews

Entire Updated Family Friendly Home in Amarillo

MorganRating, 5 stars2 weeks ago
Place was spacious enough for my family to stay and for the grandkids and their parents to come over and visit. Had everything we needed and more. Kids enjoyed the games they had there.
Top guest favorite
Home in Amarillo
5 out of 5 average rating, 28 reviews

Horned Frog Trail House

ConnieRating, 5 stars4 months ago
David’s place is in an established quiet neighborhood but still close enough to everything. House is clean and spacious with a nice back yard for the pups.

Destinations to explore