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House vacation rentals in Mira Mesa

Find and book unique houses on Airbnb

Quick stats about house rentals in Mira Mesa

  • Total vacation rentals

    Explore 210 vacation rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

  • Verified guest reviews

    Over 10,980 verified reviews to help you choose

  • Family-friendly vacation rentals

    90 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    40 properties feature pools

  • Rentals with dedicated workspaces

    140 properties have a dedicated workspace

  • Wi-Fi availability

    210 of Mira Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Mira Mesa

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A two-story house features a stylish facade with a sloped roof and decorative elements. A garage is visible on the left, with a driveway leading to the entrance. Lush greenery surrounds the home, enhancing the inviting exterior.
Home in Mira Mesa
4.94 out of 5 average rating, 214 reviews

Spacious, Yard+Patio+Beach+Zoo+Legoland

A home great for families. Conveniently 1 mile to the shopping center and popular restaurants. One block walk to a pet friendly park with playground. Just ask me for recommendations for where to go and eat! This is a popular home for families wanting to visit Legoland, Torrey State Beaches, and is only 16 minutes to Balboa Park and the Zoo! We have many outdoor amenities to help you host your group - Games, BBQ, Fire pit, dining table, outdoor sofa, and string lights throughout the backyard!

Top guest favorite
An open living area showcases modern furnishings, including a light gray sectional sofa and a sleek coffee table. A workspace with a desk and chair is positioned near a window, while a bright kitchen area features stylish cabinetry and countertops visible in the background.
Home in Rancho Penasquitos
4.94 out of 5 average rating, 132 reviews

Peaceful in Penasquitos

NO AIRBNB FEES ARE CHARGED TO GUEST. Relax with the friends and family at this peaceful place to stay. Newly remodeled kitchen, bathrooms, appliances. Child friendly. Property is off of 56 Freeway and Rancho Peñasquitos Blvd. Driving Distance: 25 mins from San Diego Convention Center 25 min from San Diego International Airport 30 mins from Legoland (North County) 20 mins from San Diego Safari Park Zoo (North County) 25 mins from San Diego Zoo 25 mins from Mission Bay 25 mins from Downtown

Guest favorite
A wooden play structure featuring a slide and windows is placed on mulch in the backyard. A green sandbox sits nearby, under a shaded tree. The fenced area provides a safe and inviting space for outdoor play.
Home in Mira Mesa
4.94 out of 5 average rating, 363 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Guest favorite
A comfortable living room features a gray sectional sofa arranged around a coffee table. A large TV is positioned against the wall, complemented by a minimalist wooden console. A rug enhances the space, while natural light enters through the windows, illuminating a decorative plant in the corner.
Home in Scripps Miramar Ranch
4.93 out of 5 average rating, 140 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Superhost
An open living space features a comfortable sofa facing a mounted television. A stone accent wall complements the modern design. In the background, a fully equipped kitchen and dining area are visible, with natural light streaming through large windows.
Home in Mira Mesa
4.82 out of 5 average rating, 268 reviews

Modern Kitchen Zen Backyard Putting Green with AC

Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Top guest favorite
A spacious living room is showcased with vaulted ceilings and wooden beams. Light-colored furnishings include a large sectional couch and striped armchairs, arranged around a decorative coffee table. Natural light enters through a window, enhancing a sense of openness and comfort.
Home in Mira Mesa
5 out of 5 average rating, 127 reviews

Beautifully designed 5 Bedroom home w/ large yard

Our cozy modern remodeled home is a beautiful 5 bedroom/ 2.5 bath, newly furnished duplex that comfortably sleeps 10. Our space is perfect for families and reunions for a relaxing getaway to either sit back and BBQ in our spacious backyard or go out and explore the city. The house is a 2 minute walk to many stores and restaurants. It is located between popular destinations like the SD Zoo - Balboa Park, Legoland, the Wild Animal Park, and La Jolla Shores.

Guest favorite
A tropical pool area is featured, showcasing a winding design with clear waters. A thatched gazebo and lush greenery surround the pool, and a water slide is visible cascading into the pool. Sunlight reflects off the surface, enhancing the tranquil environment.
Home in Scripps Miramar Ranch
4.96 out of 5 average rating, 125 reviews

Luxurious Home w/Hot Tub & Pool + Water Slide

Splash into your San Diego getaway — our private pool with a waterslide is the heart of this family-friendly tropical oasis. Sleeps 8 across 4 bedrooms, with a full kitchen, multiple living areas, a hot tub, and a built-in BBQ. Set in Scripps Ranch, under 30 minutes from downtown, the beaches, and the Wild Animal Park — and a couple miles from the lake for jogging, biking, and canoeing. Built for the kind of family trip where nobody wants to leave.

Guest favorite
A spacious kitchen and dining area features light cabinetry and modern appliances. A wooden dining table is set for meals. A ceiling fan provides airflow. Double glass doors lead to an outdoor space, while a television screen displays a program.
Home in Mira Mesa
4.9 out of 5 average rating, 178 reviews

Relaxing Sunny Diego Style & Working Remotely!

We offer monthly discounts for corporate travelers and remote workers looking to enjoy the sun, beaches, and more! The house is configured to work from home with high-speed Wi-Fi. Escape to beautiful Sunny Diego! You can enjoy and relax in this centrally located property. It's a convenient location close to Sorrento Valley, UTC, and most attractions & destinations in San Diego - the beaches, Sea World, Legoland, San Diego Zoo, and many more.

Top guest favorite
A single-story ranch home is set amidst a landscaped front yard featuring vibrant green grass and white gravel accents. A large tree provides shade by the entrance, while a well-maintained driveway leads to a garage. Clear skies add to the welcoming exterior ambiance.
Home in Mira Mesa
4.98 out of 5 average rating, 101 reviews

Charming Family 3BR w/ Game Room

Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Top guest favorite
A spacious living room features a high, beamed ceiling and large windows allowing natural light. Comfortable seating includes a blue sofa and two armchairs, arranged around a central coffee table. A stone fireplace and decorative plants add to the inviting ambiance.
Home in Mira Mesa
4.93 out of 5 average rating, 131 reviews

Open Concept modern ranch w/ bounce house included

Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

Top guest favorite
The living room features high ceilings with a modern design. Comfortable seating is arranged around a round wooden coffee table. A textured area rug covers the floor, while various plants and decorative elements add a touch of greenery. Natural light streams through the windows.
Home in Mira Mesa
4.96 out of 5 average rating, 105 reviews

Aesthetic Plant Home in MiraMesa

Our home is decorated with some modern, and French inspired fixtures along with many living plants ,please don’t touch but admire 😊 2 story home. 2 driveway parking (no garage use) 6 bedrooms, 5 beds are queens and 1 is a double 3 full bathrooms Tesla only fast charger Closest beaches La Jolla shores & Torrey Pines 20 mins away 25-30 mins to most SD attractions such Seaworld, SD Zoo, legoland, airport & downtown.

Top guest favorite
Home in Encinitas
4.98 out of 5 average rating, 511 reviews

Lux Casita with Pickleball & Resort Amenities

Escape to this inviting Casita, where bright white walls and French doors fill each room with light and warmth. Thoughtfully furnished and full of charm, it offers a serene retreat with private resort-style amenities, including a tennis court, pool, and lush gardens. Step outside to hiking and biking trails, then return to cozy comfort. An optional second suite provides extra space for a relaxed, luxurious stay.

Popular amenities for Mira Mesa house rentals

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