
House vacation rentals in Mira Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in Mira Mesa

Total vacation rentals
Explore 210 vacation rentals in Mira Mesa

Nightly prices starting at
Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 10,980 verified reviews to help you choose

Family-friendly vacation rentals
90 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
140 properties have a dedicated workspace

Wi-Fi availability
210 of Mira Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

4.8 Average rating
Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Mira Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.

Spacious, Yard+Patio+Beach+Zoo+Legoland
A home great for families. Conveniently 1 mile to the shopping center and popular restaurants. One block walk to a pet friendly park with playground. Just ask me for recommendations for where to go and eat! This is a popular home for families wanting to visit Legoland, Torrey State Beaches, and is only 16 minutes to Balboa Park and the Zoo! We have many outdoor amenities to help you host your group - Games, BBQ, Fire pit, dining table, outdoor sofa, and string lights throughout the backyard!
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Peaceful in Penasquitos
NO AIRBNB FEES ARE CHARGED TO GUEST. Relax with the friends and family at this peaceful place to stay. Newly remodeled kitchen, bathrooms, appliances. Child friendly. Property is off of 56 Freeway and Rancho Peñasquitos Blvd. Driving Distance: 25 mins from San Diego Convention Center 25 min from San Diego International Airport 30 mins from Legoland (North County) 20 mins from San Diego Safari Park Zoo (North County) 25 mins from San Diego Zoo 25 mins from Mission Bay 25 mins from Downtown
ValueFamilyGrill

Contemporary Family-Friendly Home in SD with EV&AC
Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.
ValueFamilyParks

20% OFF- Newly updated guesthome for families
Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.
LocationFamilyDecor

Modern Kitchen Zen Backyard Putting Green with AC
Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.
LocationFamilyDecor

Beautifully designed 5 Bedroom home w/ large yard
Our cozy modern remodeled home is a beautiful 5 bedroom/ 2.5 bath, newly furnished duplex that comfortably sleeps 10. Our space is perfect for families and reunions for a relaxing getaway to either sit back and BBQ in our spacious backyard or go out and explore the city. The house is a 2 minute walk to many stores and restaurants. It is located between popular destinations like the SD Zoo - Balboa Park, Legoland, the Wild Animal Park, and La Jolla Shores.
FamilyValueLaundry

Relaxing Sunny Diego Style & Working Remotely!
We offer monthly discounts for corporate travelers and remote workers looking to enjoy the sun, beaches, and more! The house is configured to work from home with high-speed Wi-Fi. Escape to beautiful Sunny Diego! You can enjoy and relax in this centrally located property. It's a convenient location close to Sorrento Valley, UTC, and most attractions & destinations in San Diego - the beaches, Sea World, Legoland, San Diego Zoo, and many more.
ValueFamilySleep quality

Charming Family 3BR w/ Game Room
Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.
ValueLocationCleanliness

Open Concept modern ranch w/ bounce house included
Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.
LocationFamilyIndoor spaces

Bright Cozy 3b/2b with nice backyard & BBQ
Relax and recharge in our cozy, family-friendly single-story home in the quiet neighborhood of Mira Mesa. Just minutes from dining, shopping, and groceries—and a short drive to San Diego’s beaches, hikes, parks, breweries, and top attractions. Enjoy a spacious living area, fully stocked kitchen, dining for 8, plush memory-foam beds, and a private turf backyard with patio seating—perfect for unwinding after a day of exploring.
LocationFamilyGetting around

Aesthetic Plant Home in MiraMesa
Our home is decorated with some modern, and French inspired fixtures along with many living plants ,please don’t touch but admire 😊 2 story home. 2 driveway parking (no garage use) 6 bedrooms, 5 beds are queens and 1 is a double 3 full bathrooms Tesla only fast charger Closest beaches La Jolla shores & Torrey Pines 20 mins away 25-30 mins to most SD attractions such Seaworld, SD Zoo, legoland, airport & downtown.
FamilyLocationHospitality

Charming & Spotless Studio with Own Entry
Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.
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Popular amenities for Mira Mesa house rentals
House rentals with a pool

Luxury family escape: Private pool paradise
ValueLocationGetting around

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
FamilyLocationAccess

Resort-Style Villa - Pool, Spa & Views
FamilyValueBackyard

Surf Cottage w/Pool & Firepit 10min from the beach
ValueFamilyKitchen

Luxury San Diego 5 Bedroom Oasis
LocationFamilyHeating

the Belvedere
ValueLocationLayout

3 Bed w/ Pool, Spa, Game Room, Family Friendly
LocationFamilyCheckout

San Diego Oasis- A Retro Retreat w/ King Size Bed!
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Weekly house rentals

Dream 3BR HOUSE San Diego - Spa BBQ Playroom
ValueFamilyNearby

5 Min > Convoy | King Bed | Parking | Private Yard
FamilyValueCleanliness

Del Mar LoveShack
LocationValueBiking

Tropical Paradise In Sunny San Diego!
LocationValueAmenities

Luxury 2 bedroom home with BBQ
ValueFamilyIndoor spaces

Coastal Paradise - Luxury Spacious Resort Living!
LocationFamilyCheckout

Private Home 1 bd, 1 ba, W/D & Private Backyard
LocationValueAmenities

Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
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Private house rentals

A Romantic Family Retreat Home - Game room-Hot tub
ValueLocationCheck-in

Bright & Spacious | Modern Getaway
LocationQuietBathroom

Mira Mesa Gem | Quiet 4BR Home Near Everything
ValueFamilyTV

Pixel Palace•Spa•Gameroom•Theatre•Sleeps 14
ValueLocationSleep quality

Newly Remodeled Luxury Home
LocationValueAmenities

HotTub~Cozy~Sunny~FamilyFriendly~SDCentral
LocationFamilyHot tub

A Luxury 4BR Home in San Diego, 8-10 guests
LocationComfortAccuracy

Cozy 5BR Oasis | Heated Pool & Patio | Sleeps 12
FamilyValueAccuracy
Destinations to explore
- Private suite rentals Mira Mesa
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- Rentals with a hot tub Mira Mesa
- Rentals with pools Mira Mesa
- Family-friendly rentals Mira Mesa
- Pet-friendly rentals Mira Mesa
- Hotel rooms Mira Mesa
- House rentals San Diego
- House rentals San Diego County
- House rentals California
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- SeaWorld San Diego
- Coronado Beach
- LEGOLAND California
- Rosarito Beach
- University of California-San Diego
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Tijuana Beach
- Balboa Park
- San Diego State University
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Oceanside City Beach
- San Clemente State Beach
- Las Olas Resort & Spa
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego





