
House vacation rentals in Little Italy, San Diego
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Top-rated house rentals in Little Italy, San Diego
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Popular amenities for Little Italy, San Diego house rentals
House rentals with a pool

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa
Our home away from home. The property was conveniently located to major stores. It is 30 minutes to the San Diego Zoo, Birch Aquarium, and Sesame Street. The house is very spacious and brings in light energy. Our family loved the beds and comfy pillows which can make or break a vacation. The bathrooms were spacious and worked conveniently with the needs of our family, especially the Bluetooth speakerđ. The backyard was our favorite! Beautiful space during the day with plenty of space for our 3 year old to run. Serene and chill views in the evening. We 100% recommend this property for your family. And would definitely stay again.

Your Modern Lux Pool Resort in the Heart of SD
Stay at Katriâs was great. Had delicious cookies waiting for us when we checked in, which was a breeze. House was spacious and entire lot was very big. Pool was great and even after we had told them that no heated pool would be necessary, Mother Nature had a different idea and gave us some more than unexpected chilly weather, so they had no problem throwing the heater on for us. Freeway in the background was hardly a noise problem for us personally. Just far enough that it didnât affect us, and was nice to see what our morning commute was going to be like. Brought two dogs with the group that absolutely loved everything (after one of them finally got over his fear of the staircase). All in all a great stay in a great neighborhood. Cant comment more how quickly they responded to us in the days leading up to the trip, and while we were there. Great hosts!

Luxurious North Park Home - Walk to Dining & Shops
We loved our stay at Mari Katherineâs Airbnb for a girlâs weekend in SD! It is a beautiful home that was spacious and thoughtfully designed and decorated to create a warm and welcoming atmosphere. The home feels private, but was in a fantastic location in North Park that was easily walkable to coffee shops, restaurants, etc. Mari Katherine sent clear instructions leading up to our stay, so the logistics of check in were clear and easy! When some logistical challenges came up during our stay, Mari Katherine was very responsive (even late in the evening) and offered solutions - we would be thrilled to visit again!

Lionhead - Private Boutique Home
Quiet location, exactly as pictured and described. Parking could be a challenge if you have a large vehicle but being able to park in the garage made it easier. Great communication!

University Heights Oasis Getaway
Exactly as the other reviewers have described, it is just a beautiful oasis in a perfect quiet neighborhood. Donât wait, book now!

Oasis with ocean views/Pool/Hot tub! Sleeps 10!
Van was very friendly, even had great food recommendations for my family and I. The home was one of the best Airbnbs Iâve ever stayed in. My children thought we were in a place of royalty with how well put together the house was. Loved our stay and will definitely be back

5BR | Salt Water Pool | Hot Tub | Fire Pit| BBQ
The place was clean and well-kept. The 5 rooms had comfortable beds and individual A/C units, adding to the comfort. The backyard was great for hosting. The only minor criticism was the lack of instructions for the fire pit. I managed to turn it on successfully; it produced a strong fire, perfect for cozy nights. There was adequate seating for everyone. Inside, the house felt clean, including the bathrooms. The living room had a large couch and the dining area had a large table, accommodating our group's size. A small improvement would be to hang the towels in the bathrooms to avoid a scavenger hunt. The wifi was down upon arrival and never regained function despite troubleshooting, but my cellular service (T-mobile) was sufficient. The host was very communicative and responsive throughout my stay. I didnât receive dining recommendations, but it was easy to find places to eat.

Canyon House: Sunset View Tranquil Private Pool
Jessicaâs home is beautiful and located in a lovely neighborhood that is close proximity to many things. We came to celebrate the graduation of my niece and Jessicaâs home was a great place for the family to connect, rest between events and spend time together! Her home is beautifully appointed and was perfect for our stay. Jessica is a great host who communicates with her guests and is very responsive! Her home is filled with good energy and I would definitely book again! for future family events when visiting San Diego!
Weekly house rentals

Ocean View in the Heart of Ocean Beach/Point Loma
Wonderful place and an exceptional host! The host was warm and welcoming, making our stay even more enjoyable. The property was in a great locationâvery close to scenic spots like Ocean Beach, Sunset Cliffs, and La Jolla. I would highly recommend this place and would definitely consider staying here again on my next trip to San Diego.

Charming Coastal Cottage- close to beach/ downtown
I had a wonderful stay at this Airbnb! The house was incredibly quiet, which made for a relaxing and peaceful getaway. I absolutely loved the aestheticâthoughtfully designed, cozy, and full of charm. Everything was spotless and well-maintained, which made it feel even more comfortable. Highly recommend if you're looking for a serene and stylish place to unwind!

Walkable North Park Urban Oasis with Private Yard
This a great home base for an outstanding stay in North Park. We loved the small backyard for our dog! The house was cozy and extremely comfortable. We slept so well all three nights of our vacation The location is amazing. Itâs a short walk to dozens of restaurants and bars/breweries. Highly recommend this place!!!!!

Mid-century house in the heart of North Park
I stayed here for the Rock n Roll Marathon and it was the best location for my family to be able to walk 2 min and greet me mid race. Loved the place and everything was close!

Private Luxurious Rooftop Deck & Private Jacuzzi.
Robs place was very cozy and suited my wife 3 year old and myself quite nicely. The location is great for a La Jolla trip, downtown and the San Diego zoo. It fit our needs perfectly and their jacuzzi is the nicest one my wife and I have seen (we usually prioritize jacuzzis for our stay). They were polite and even accommodated a 2 hour earlier check in for us as we had our 3 year old with us and they get fiesty đ. Thank you to everybody associated with this location, it was amazing

Spacious, centrally located, elegant Craftsman
We had a great stay at Ruth's place and would absolutely stay here when visiting San Diego again. The location was centrally located between everything we had planned for our vacation. The beds were so comfortable and the place was very clean. Ruth is very friendly, responsive and event let us drop our bags by when we landed so we did not have to lug our suite cases around the zoo before check in. I think the best part was getting to enjoy the front porch watching the planes land to unwind in the evenings. Thank you Ruth for making this stay so great!

Little Italy Historical
In more than 40 AirBnB stays around the world over the past 10+ years, this property was one of the best for me. Was traveling solo, but tons of room, great ammenities for the bathroom and sleeping. If you are looking for a full blown kitchen its not the right place as there is no dishwasher or stove/oven. There is however a microwave, air fryer coffee maker and full sized fridge. But, remember your a 3 block walk to some of the most amazing fresh meals in Little Italy and I did a lot of that. Plenty of bars to relax and chill and a great ice cream place called Salt and Straw that is always crowded. Remember CA pricesw, so things are a bit more expensive. Michael was a great host. I would def stay here again. Thanks Michael.

Quaint Studio for 2 in the Heart of Little Italy!
This place is great for a weekend in Little Italy, as itâs walkable to so many restaurants! We had a great time. The code was messed up upon our arrival, but the host was immediately responsive to clear up the issue! We would definitely stay again.
Private house rentals

Bright & Modern OB Getaway
Lindsey was an amazing host and the place was just as amazing! very nice and cozy inside and it was in a perfect location about 15 minutes from downtown. every place we had planned for the trip was very close and the beach less than 4 minutes away was a nice plus! it was very clean we spilled water on the floor and when we wiped it up the paper towel came up still white! i would definitely stay here again :)

Shadow House Mt. Helix
The most beautiful Airbnb! The location was amazing, it was very secluded. The hosts make you feel right at home.

Renovated private ADU & spa, Mission Bay/ SeaWorld
My stay here was exactly how I wanted it to be. The home was very clean and had a lot of necessities like cookware, silverware, shower products, and so much more! Everything was super neat and organized. The bed was extremely comfy. The host was very easy to communicate with and made sure we had everything we needed, also made sure all our questions were answered. I am looking forward to staying here again when I return to San Diego. I would definitely recommend this to anyone who is thinking about staying here. You definitely get your moneys worth.

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
Beautiful accommodation wonderful kind professional hospitality. Thanks for a lovely stay!

Coastal Chic Retreat in Bankers Hill
Great location within walking distance to everything we needed and wanted. Airplane noise overhead was a bit much at times, but it was expected from the listing. We quickly got used to the noise. Hosts were friendly and quick to respond to questions. Check-out was simple. Overall very happy with the stay.

Stylish&Comfy~Studio~Parking
Enjoyed my stay here! The location was great and close to a lot of stuff. The bathroom and kitchen were very spacious which I enjoyed. Parking was easy and there was always a spot available in the driveway or front of the house. Overall, enjoyed my stay and the space!

On The Beach Casita - Bay front access
Gorgeous Airbnb on an almost private beach. Location is great for those who know the area. Only one bedroom and patio space is shared with other unit. But the view and serene environment made up for it :)

Entire House with Private Yard
My stay there was great! The house was very clean and easy to travel and get around!
Quick stats about house rentals in Little Italy, San Diego
Total rentals
70 properties
Nightly prices starting at
ïș©.ïș220 before taxes and fees
Total number of reviews
5.4K reviews
Family-friendly rentals
50 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Destinations to explore
- Loft rentals Little Italy
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- Rentals with a hot tub Little Italy
- Family-friendly rentals Little Italy
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- Rentals with outdoor seating Little Italy
- Rentals with a fire pit Little Italy
- Rentals with a fireplace Little Italy
- Pet-friendly rentals Little Italy
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- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- Coronado Beach
- La MisiĂłn Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Belmont Park
- Liberty Station
- Moonlight Beach
- Sesame Place San Diego
- Playas Los Buenos
- Playa Popotla
- USS Midway Museum
- Torrey Pines Golf Course
- Hillcrest