Places to stay in Little Italy, San Diego

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Top-rated places to stay in Little Italy, San Diego

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Top guest favorite

A modern multi-level building showcases white stucco exteriors and various balconies. Lush greenery and palm trees surround the property, providing a vibrant contrast against the bright architecture. Neighboring homes offer glimpses of a charming residential area, with the distant ocean visible beyond the rooftops.

Guesthouse in Mission Hills

5 out of 5 average rating, 186 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Guest favorite

Loft in Little Italy

4.96 out of 5 average rating, 75 reviews

Contemporary Loft with Harbor & City Views

Book this spectacular contemporary loft with 25-foot ceilings and views from every window! Located in the heart of Little Italy, an area with a walking score of 9.8/10, and near great restaurants, bars, and shops. The unit is meticulously designed with huge bright windows, electric shades & contemporary high-end furnishings, and artwork. Only steps from the waterfront, you can decide if you want to sip cocktails and sample cuisine in the night scene or relax all day walking along the waterfront.

Superhost

A modern living area is seen with high ceilings and a light color palette. A sleek, tan sofa faces a large television. A patterned area rug lies beneath a round table, surrounded by a chair and pouf. Natural light streams in through the large windows.

Townhouse in Little Italy

4.79 out of 5 average rating, 154 reviews

Contemporary, Fully Renovated Loft in Little Italy

Book this spectacular contemporary loft with 25 foot ceilings & views! The loft is in an area with a 9.8/10 walk score & known for having the best restaurants, bars &shops. The unit is newly renovated & meticulously designed with bright windows, contemporary high-end furnishings & an everyday spa inspired bathroom. Only steps from the waterfront, you decide if you want to enjoy cocktails & cuisine in the night scene or relax all day walking along the harbor. Free parking spot with access to all.

Guest favorite

An outdoor seating area features plush circular pink chairs around round tables, highlighted by warm ambient lighting. A bar area extends along one side, with sleek gold accents. The vibrant city skyline is visible in the background, under a twilight sky.

Apartment in Little Italy

4.92 out of 5 average rating, 315 reviews

PENTHOUSE + VIEW DECK Urban Design in Little Italy

Cozy memory foam King-size bed with two additional sleeper sofas! This penthouse suite is located in the heart of San Diego's highest rated neighborhood, Little Italy! Quick and secure access. Boasting over 36 retail establishments within a two block radius! Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Guest favorite

A modern apartment building features a combination of sleek architecture and natural wood accents. Large windows are framed by dark panels, allowing for ample natural light. Lush trees line the entrance, enhancing the urban landscape.

Apartment in Little Italy

4.93 out of 5 average rating, 137 reviews

Modern Inner City Pad w/ Patio | Walk Everywhere!

Enjoy everything Little Italy has to offer right on your doorstep from this bright, light and inviting apt. Open the floor-to-ceiling glass doors and let the sounds of the city in as you relax on the lounge and shaded patio. Cook in the modern kitchen, feel pampered in the luxe bathroom, then retire to the chic, king bedroom. Explore quaint streets, cafes, gelato shops, and charming trattorias just steps away then discover downtown, Balboa Park, & the Gaslamp Qtr, an easy 5/10 min drive away!

Superhost

The two-story building features a light-colored exterior with large front windows and a welcoming entrance. A staircase leads to the upper level, while two garage doors are visible below, providing access to parking. Lush greenery in a pot adds a touch of nature to the entrance.

Bungalow in Little Italy

4.88 out of 5 average rating, 297 reviews

Explore Little Italy from this Gorgeous Mini Villa

La Scala rises from the center of Villa Little Italy in the heart of San Diego’s most popular restaurant and entertainment district. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

Superhost

The living room features a spacious sectional sofa with orange and gray accent pillows. A modern coffee table sits in the center, complemented by a sleek television on a wooden stand. Natural light filters through large windows draped with sheer curtains, enhancing the airy atmosphere.

Townhouse in Little Italy

4.82 out of 5 average rating, 756 reviews

BEST LOCATION in all of Little Italy & downtown!

Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Superhost

A compact kitchenette is visible, featuring white cabinetry and stainless steel appliances, including a refrigerator. Two wicker chairs are placed around a small marble table. Natural light enters through the windows, which are adorned with white blinds, and warm wood flooring complements the brick wall.

Guest suite in Little Italy

4.84 out of 5 average rating, 138 reviews

Little Italy Downtown Boho 1BD w/ Private Patio

This remodeled studio is a couple blocks away from shops, restaurants + bars in Little Italy/Downtown SD. Centrally located & minutes from the airport w/ plenty of free street parking. Guests can also reserve the driveway for an additional fee. Walking distance to: - Waterfront Park - USS Midway - Balboa Park (half a mile) - Little Italy - Seaport Village - Embarcadero Short drive to: - Petco Park - Beaches (PB, Coronado, Ocean Beach, La Jolla) - Liberty Station/Point Loma - North Park

Superhost

A modern living area features a green sectional sofa with natural wood accents, arranged around a round coffee table. A large framed artwork is displayed on the wall, complemented by a decorative hanging element. Lush greenery from a tall potted plant adds a touch of nature.

Loft in Little Italy

4.83 out of 5 average rating, 326 reviews

Stylish Downtown Loft w/ Parking in Little Italy

Stylish Modern Loft In The Heart Of Little Italy. Immerse Yourself In San Diego's Trendiest Neighborhood With A Stay In This Elegant Loft. Featuring Exposed Brick, Tall Ceilings, A Cozy Loft Bed Accessed By A Ladder, And An Open Layout Adorned With Stunning Artwork, This Space Blends Charm And Sophistication. Enjoy Vibrant Culture, Renowned Dining, And Little Italy’s Lively Atmosphere—All Steps From Your Front Door. Includes 1 Free Onsite Parking Spot. 1 Dog Accepted With A $50 Pet Fee.

Guest favorite

Guesthouse in Bankers Hill

4.88 out of 5 average rating, 65 reviews

Upper Suite on Ivy St - Walk to Little Italy!

Welcome to the Ivy Street Suites! Your gateway to the best San Diego has to offer -- conveniently located within the buzzing restaurant district of both Little Italy + Bankers Hill. Drop your bags + explore the San Diego Zoo, Balboa Park, USS Midway Museum + the infamous Little Italy Mercato! All within a nice stroll from the space. Upper + Lower Suites which can be rented together or separately, with a shared courtyard + private deck/patio each. This listing is for the upper suite.

Superhost

The exterior of a restaurant features large, double doors flanked by greenery, creating an inviting entrance. The wooden façade showcases an industrial design, complemented by soft lighting above. The sidewalk is paved, leading up to the rustic styled entrance.

Apartment in Little Italy

4.85 out of 5 average rating, 366 reviews

Entire 2Bd in Most Convenient San Diego Location

Amazing, private apartment home is located in the most convenient location in San Diego. Beautiful Bankers Hill is blocks from Little Italy and just down the road from breathtaking museums and outdoor activities at Balboa Park. Spacious 2br/1ba with professional cleaning and management. Your entire, private apartment comes equipped with high-end appliances, renovated finishes and furnishings, and breath taking views of the city skyline and San Diego Harbor surrounding the property.

Guest favorite

The open kitchen features a stone countertop and white cabinetry, complemented by three bar stools. Modern stainless appliances are present, with pendant lighting hanging above. A view into the connected powder room is visible through a sliding door.

Condo in Little Italy

4.88 out of 5 average rating, 105 reviews

NEW Stylish❤️ of Downtown Little Italy w Parking/AC

Located in the heart of Little Italy San Diego, this street level condo has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. *AC w/ independent temp control in each room *Voice Controlled Sound System, 4K TVs in every room *Beautiful bathroom w/ dual showers *Walk to coffee, yoga & gyms, dining, entertainment, shopping! 6 min to Zoo 5 min Airport 9 min to SeaWorld 6 min Petco Park 8 min to Coronado

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Popular amenities for Little Italy, San Diego places to stay

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Other great vacation rentals in Little Italy, San Diego

Guest favorite

A spacious sleeping area is highlighted by a queen-sized bed, softly dressed in neutral linens and adorned with decorative pillows. The environment features exposed concrete walls and is illuminated by table lamps. A cozy seating area is positioned nearby, enhancing the room's comfort.

Apartment in Little Italy

4.94 out of 5 average rating, 157 reviews

State & Fir (Little Italy Loft, Free Parking)

PatriciaRating, 5 stars2 weeks ago

Thank you for your speedy communication! I appreciated our stay and would stay here again.

A lively street scene showcases the Parakeet Cafe, featuring large windows and outdoor seating surrounded by tropical plants. An Italian flag is displayed prominently, and vibrant umbrellas provide shade for patrons at nearby tables, creating an inviting atmosphere for enjoying meals outdoors.

Hotel room in Little Italy

4.65 out of 5 average rating, 159 reviews

Little Italy location near dining & theme parks

AmyRating, 5 stars2 weeks ago

Great location, you have to pay $25 a night for parking. Room is small but was perfect since we were just there to sleep

Guest favorite

The exterior of Villa Little Italy is showcased, featuring a modern Art Deco design with smooth white walls and circular windows. A wooden fence secures the patio area, while potted plants add greenery. The building is positioned at an angle, capturing the inviting entrance.

Bungalow in Little Italy

4.94 out of 5 average rating, 355 reviews

Gorgeous 2Bd Corner Bungalow in Little Italy

MarcoRating, 5 stars3 weeks ago

Great location. Just as pictured. Very walkable to many places around the neighborhood and to public transportation. Location could use some curtains. Great location to explore San Diego.

Superhost

A wooden gate marked with '435' stands closed at the entrance to the property. Light brick pavers create a walkway leading up to the gate, while potted greenery can be seen attached to it. Windows of adjacent buildings are visible on either side.

Cottage in Little Italy

4.84 out of 5 average rating, 182 reviews

Stylish, cozy studio in the heart of Little Italy

ChristineRating, 5 stars3 months ago

A perfect place for a weekend getaway! It truly is in a prime location. Everything is easily walkable. Safe neighborhood. So many phenomenal restaurants to choose from. George was an excellent host. Hotel quality linens. Clean. With plenty of amenities to make it feel like home. We would easily stay here again.

Guest favorite

An expansive outdoor patio is showcased, featuring a comfortable sectional sofa with soft cushions and a stylish coffee table. Bi-folding doors connect to a modern kitchen area adorned with sleek cabinetry. The distant view reveals the San Diego coastline under a clear blue sky.

Apartment in Little Italy

4.93 out of 5 average rating, 171 reviews

Calm Luxury Penthouse Getaway With Panoramic Views

NancyRating, 5 stars1 week ago

I highly recommend Jessica’s place. It was clean, well stocked with everything one would need for a lengthy stay, and nicer and bigger than the photos. Great view of downtown, little Italy and the water from the huge patio that had ample seating. Jessica was a very friendly, responsive and accommodating host. The elevator has access directly into the suite which made going in and out very convenient. The area felt very safe and there are many restaurants and cafes nearby. While it was close to the airport and had airplanes flying by, the noise was minimal and not at all a problem at night. My only suggestion for guests is to bring sleep masks if you plan on sleeping on the bunk beds as that area does not have dark/black out blinds and is bright in the morning. All in all a great stay and would come back in a heartbeat.

A panoramic view is offered, showcasing a bustling waterfront area with boats in the marina and palm trees lining the street. Colorful buildings filled with shops are visible, leading down to a plaza where people are gathered around a fountain.

Hotel room in Little Italy

4.69 out of 5 average rating, 13 reviews

Queen Studio in the Heart of Little Italy

CaylinRating, 5 stars1 week ago

we enjoyed our time, everything was nice and neat, and check in was very easy.

Superhost

A neatly made bed is paired with a soft gray headboard and white bedding. A nightstand holds a small potted plant and a lamp, with stacked books beneath. Natural light enters through the window, highlighting the room's clean aesthetic.

Bungalow in Little Italy

4.87 out of 5 average rating, 358 reviews

La Giardino, a Stylish Mediterranean Bungalow

NagiRating, 5 stars1 month ago

Great place. Great location. Great host!

Superhost

A spacious living area features a comfortable sofa facing a low coffee table and a flat-screen television. Stairs lead to a lofted space, while the adjoining kitchen is equipped with a gas stove and sink. A large green plant adds a touch of greenery.

Loft in Little Italy

4.77 out of 5 average rating, 798 reviews

Good Vibe (Little Italy Loft, Free Parking)

MattRating, 5 stars1 month ago

Where we stayed felt like a home; a home away from home. This place was located in one of the greatest spots of San Diego, every restaurant and place I wanted to go to was right around the corner! The place is breathtaking! Should be on DesignMilk or on a cover of some magazine! The host(s) we’re very kindhearted, helpful, and friendly! Would book again in a heartbeat

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Quick stats about vacation rentals in Little Italy, San Diego

Total rentals
540 properties
Nightly prices starting at
ﺩ.ﺇ37 before taxes and fees
Total number of reviews
30K reviews
Family-friendly rentals
200 properties are a good fit for families
Pet-friendly rentals
150 properties allow pets
Rentals with a pool
140 properties have a pool

Places to stay in Little Italy, San Diego

Top-rated places to stay in Little Italy, San Diego

Vacation rentals for every style

Popular amenities for Little Italy, San Diego places to stay

Other great vacation rentals in Little Italy, San Diego

Quick stats about vacation rentals in Little Italy, San Diego

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Family-friendly rentals

Pet-friendly rentals

Rentals with a pool

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