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Vacation rentals in Isla Grande

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Top-rated vacation rentals in Isla Grande

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Guest favorite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 113 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Superhost
Home in Isla Grande
5 out of 5 average rating, 3 reviews

BeachfrontHouse+Kitchen+Balcony+AC+WiFi@IslaGrande

✔️SuperAnfitrión Verificado ¡Tu estadía estará en las mejores manos! 🚨Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones especiales 📍 Apartamento en Isla Grande, Provincia de Colon, Panamá 🇵🇦 🏡 Espacio limpio, cómodo y seguro, con excelente ubicación 🧼 Dotado con insumos y productos de limpieza Durante tu reserva, tu Airbnb cuenta con: 🌐Wifi 📺TV 🍳Cocina 🌊Frente al mar ❄️A/C 🚗Parqueo 👉Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones

Top guest favorite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
4.98 out of 5 average rating, 57 reviews

CARA AL MAR Cacique (Parque de Portobello)

Une maison ! véritable îlot de verre au cœur de la jungle ! Au beau milieu du Parque National de Portobello (accès uniquement en 4x4 AWD) blotti au sommet de la colline, entre ciel/mer, à l'abri de tout regard, une maison transparente où le verre épouse la nature de tous côtés créant une connexion unique entre l'intérieur et l'extérieur, ideal pour se reposer, se déconnecter, confortable, spacieuse, fraîche (clim centrale), exclusive. Elle est le témoin d'un spectacle grandiose qui vous attend !

Guest favorite
A two-story building is surrounded by greenery, featuring a balcony that overlooks the lawn. Large windows and doors are visible, allowing natural light to enter. A rustic structure with a red-tiled roof is seen to the right, contrasting with the white exterior of the main house.
Home in Santa Rita Arriba
4.94 out of 5 average rating, 17 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favorite
A tranquil view of the clear, shallow waters of the Caribbean Sea is displayed, with gentle waves lapping against the shore. Smooth stones are partially visible above the waterline, and a distant mountain range is seen against a backdrop of scattered clouds.
Apartment in Maria Chiquita
4.95 out of 5 average rating, 141 reviews

Spacious 4Br Beachside Getaway at Playa Escondida

Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

Guest favorite
Serene waters reflect vibrant greens and blues, surrounded by lush vegetation. Two sailboats are anchored nearby a rustic hut, offering a glimpse of a tranquil lagoon. The distant hills cradle the scene, enhancing a connection with the natural landscape.
Home in Portobelo
5 out of 5 average rating, 15 reviews

AeolusGuestHouse Home in Portobelo National Park

Welcome to AeolusGuestHouse, a hidden retreat in Jose del Mar, inside the Portobelo National Park. Surrounded by protected jungle, mangroves, and calm lagoon. Ideal for disconnecting in nature. Kayaks are available, and boats pick you up at the dock in front of the house for local tours, including Venas Azules just 15 minutes away. The home offers 2 bedrooms, 4 beds, an equipped kitchen, AC, parking, and helpful hosts always ready to assist. Pure nature, zero crowds, unforgettable stays.

Guest favorite
A spacious wooden chalet is positioned on a lush green slope, surrounded by tropical vegetation. The structure features an open terrace with railings, allowing for expansive views of the sky. A few palm trees and various plants complement the natural landscape.
Home in Cacique
4.97 out of 5 average rating, 30 reviews

El Paraíso

Nous avons le plaisir de vous présenter une grande maison magnifique à louer entre le village de Cacique et le village de José Pobre dans le parc national de Portobelo. Surplombant la mer des Caraïbes , nichée en pleine jungle , cette maison a un cachet unique dans la région . Son accès direct à une petite plage sauvage , dotée d’ un récif passionnant pour les fans de snorkeling en fait un lieu privilégié. Idéale pour les groupes et les familles désirant se Re- connecter avec la nature .

Guest favorite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Apartment in Juan Gallego
4.88 out of 5 average rating, 153 reviews

Pebos Reef Apt 2 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favorite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.97 out of 5 average rating, 86 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favorite
Home in Maria Chiquita
4.98 out of 5 average rating, 45 reviews

“Hermosa y Cómoda Villa en Playa Escondida Resort”

Luxury Resorts y Villa, front lagoon view y playa solamente a 2min, Disfruta de una estadía cómoda y tranquila en este alojamiento totalmente equipado, ideal para matrimonios, familias, grupos pequeños o viajeros de negocios. Tiene capacidad para hasta 6 huéspedes, ofreciendo un ambiente acogedor, limpio y funcional,una terraza amplia,sin duda para una estancia agradable,

Superhost
An outdoor seating area is presented with four woven chairs positioned around a rectangular table. The view reveals a serene sea in the background, with a well-kept grassy area and scattered rocks leading to the water's edge. Bright sunlight enhances the peaceful atmosphere.
Home in La Guaira
4.69 out of 5 average rating, 180 reviews

Casa "El Terrenito" - Ocean Front

Amplia casa frente al mar con 2 habitaciones, una hab. con 3 camas queen y 2da con una king y una twin. Cocina, sala, comedor. Tiene todos los implementos para cocina, sabanas, estufa,nevera, A/C. Especial para relajarse!! Para fanáticos de la pesca podemos proporcionar una panga de pesca! Precio adicional por día y el capitán. Puede llevar mascota.

Guest favorite
A tranquil view of modern villas stretches alongside a large swimming pool, featuring clear blue water that reflects the sky. Lush greenery borders the pool area, contributing to a serene atmosphere. The elegant architecture of the villas is complemented by a backdrop of peaceful clouds.
Villa in Maria Chiquita
4.85 out of 5 average rating, 142 reviews

Disfruta espectacular Villa en Playa Escondida

Playa escondida Resort & Marina, es una joya del Caribe , una de las playas más hermosas y exclusivas , a una hora de la Ciudad de Panamá, ubicada en Maria Chiquita, Colón. Nuestra exclusiva Villa , cuenta con un jacuzzi natural en la terraza con acceso a la piscina y a un 1 mint a pie la playa .

Popular amenities for Isla Grande vacation rentals

Frequently Asked Questions

  • Where is Isla Grande located?

    Isla Grande is situated just off Panama's northern Caribbean coast, in Colón Province. It is found near the entrance to the Portobelo National Park area, surrounded by tropical waters and natural scenery.

  • When is the best time to visit Isla Grande?

    Travelers frequently suggest visiting Isla Grande during the dry season for clearer skies and calmer seas. The rainy months bring lush landscapes and a quieter atmosphere, with both offering distinct ways to experience the island.

  • What are some things to do near Isla Grande?

    You can explore sandy beaches, snorkel around coral reefs, and experience local seafood restaurants on Isla Grande. The island also has relaxed walking paths and is known for welcoming Afro-Caribbean cultural influences and music.

  • How is the weather near Isla Grande?

    Isla Grande typically has a warm, humid tropical climate year-round, with temperatures often between 77 and 88°F (25 and 31°C). Rain is common outside of the dry season, and brief showers can occur throughout the year.

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