Some info has been automatically translated. Show original language

House vacation rentals in Guadalupe River

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe River

Guests agree: these houses are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Guest favorite
Steps extend from the wooden deck towards a tranquil river, surrounded by lush greenery. The water reflects the sky, showcasing shades of blue and green. Sunlight filters through the trees, creating a serene outdoor environment.
Home in Canyon Lake
4.94 out of 5 average rating, 178 reviews

The River House Guadalupe

Welcome to Fluss Haus Guadalupe located on 1 acre on the beautiful Guadalupe River in the Texas Hill Country! Enjoy your own private river access right in our shady backyard, or travel just 5 mins to the Horseshoe or Canyon Lake, 20 mins to Historic Gruene, or 25 mins to Schlitterbahn in New Braunfels. This property offers a great river house (Fluss Haus) experience for those looking to relax and enjoy time with friends & family in the Texas Hill Country. Pet friendly! (2 pet limit, small fee)

Top guest favorite
The cabin is surrounded by lush trees, with a spacious deck offering outdoor seating. A rocky path leads to the entrance, and kayaks are visible on the side. Natural stone and greenery frame the area, creating a serene atmosphere in the Texas Hill Country.
Home in Wimberley
4.98 out of 5 average rating, 691 reviews

Salvation Cabin

Wimberley's #1 rated award-winning “Salvation Cabin" is in the beautiful Texas Hill County wilderness with outdoor exploration, hiking and a Blanco Valley porch view to observe birds, deer and other wildlife. A throw back to gentler times, you'll leave here touched by nature's healing power. Come and be restored. 500+ visitors testify this is a one of a kind place. Please note* the Hill Country area is in drought presently in 2025. Blanco River dry, but Cypress Falls Swimming Hole close by.

Top guest favorite
Industrial-style metal pipes are prominently featured, creating a unique steampunk aesthetic. An antique gauge with a circular face and clear numeric indicators is visible, contributing to the immersive atmosphere of the space.
Home in San Antonio
5 out of 5 average rating, 337 reviews

The Sherlock Home a House of Conundrums!

The Sherlock Home is an immersive overnight experience. Please note- due to its unique escape-like intricate game there is an extra guest fee of $40 per guest over the initial two guests. Become Sherlock Holmes surrounded by a Victorian/steampunk setting filled with puzzles and conundrums to solve while you stay. The Sherlock home is like no other Airbnb. If you are looking for a one-of-a-kind adventure, come stay and play at The Sherlock Home. Deduce, decode, decipher -The game is afoot!

Top guest favorite
A rustic stone building is partially shaded by trees, featuring vibrant red doors and windows. The word 'BAKERY' is displayed prominently on the front. Colorful chairs are arranged in a cozy outdoor seating area. Lush greenery and a gravel path create a welcoming entrance.
Home in Helotes
4.9 out of 5 average rating, 271 reviews

Texas Grounds Coffee Co. Bed and Breakfast

Nestled in the heart of Old Town Helotes, our 107-year old house is home to our beautiful bed and breakfast upstairs and our incredible coffee shop downstairs! The space is the entire second floor! With tons of natural light, feel free to people watch from the sunroom, or snuggle in the cozy living room! Enjoy the double-headed shower! Delicious smells of pastries and coffee roasting on site tempt you into the shop early! Check out the surrounding antique shops, clothing boutiques and more!

Top guest favorite
Two colorful lounge floats rest on the clear, shallow waters of the Medina River, surrounded by smooth rocks and gentle ripples. Lush green trees line the riverbank in the background, under a bright, blue sky dotted with fluffy white clouds.
Home in Pipe Creek
4.97 out of 5 average rating, 135 reviews

La Hacienda Rio on the Medina River - Tranquility Life

Come and enjoy the tranquility of the beautiful Medina River. The house sits on 2 acres and is privately located with 150ft of river front. Relish the beauty of nature and refresh yourself by relaxing & exploring the calm crystal water of the Medina River. At the end of the day relax on the 40ft Texas size covered porch overseeing the hill county. By night enjoy a cozy fire. La Hacienda Rio is a newly built home with all the furnishing and amenities you'll need to enjoy your stay.

Top guest favorite
A cozy living area is featured with two wooden chairs positioned near a decorative fireplace. A TV is mounted above the mantle, while a round wicker coffee table rests on a textured area rug. Natural light enters through a nearby window.
Home in Alamo Heights
4.99 out of 5 average rating, 221 reviews

Stylish, Charming Home In The Heart of San Antonio

Featured in Condé Nast Traveler. Enjoy a newly remodeled and tastefully designed home in a charming, elegant neighborhood in the heart of San Antonio. Our home is located in the Alamo Heights neighborhood, known as one of the best places to live in San Antonio & surrounding areas. Relax in our warm and welcoming home which is in close proximity to downtown, the airport, and major go-to spots and top restaurants in the city. We hope you have a wonderful stay in our beautiful home!

Top guest favorite
The exterior of Casa Grande is showcased among surrounding trees, featuring a combination of stone and wood. A covered porch with large windows invites natural light, while a stone wall and landscaped areas enhance the outdoor space.
Home in Wimberley
5 out of 5 average rating, 106 reviews

Riverfront home on 40 acres w/ firepit, hot tub

Casa Grande @ Shade Ranch is a 3 bed/2 bath home on a bluff overlooking the Blanco River on a beautiful 40-acre property offering tranquility and seclusion and 600+ feet of private river access–all within the Wimberley city limits! The house offers over 2,800 square feet of space for family entertainment. With two large living areas, three dining areas (2 indoor and 1 outdoor), fire pit, hot tub and bocce ball court Casa Grande is perfect for family or large group gatherings.

Guest favorite
Home in Seguin
4.93 out of 5 average rating, 104 reviews

Waterfront Family Getaway: Dock, Kayaks & Fire Pit

Waterfront adventure awaits at Camp Guadalupe! Private dock, kayaks & SUPs, inflatable dock and a glowing fire pit set the scene for easy family fun. Inside: 4 comfy bedrooms, full kitchen, fast Wi-Fi and smart TVs. ☀️Step-in River access ☀️Outdoor Dining & BBQ ☀️Board Games, ping pong & foosball ☀️5 min to downtown Seguin ☀️Superhost Service After a day on the water, gather around the fire for s’mores under the stars. Ready for memories? Reserve your stay today!

Top guest favorite
A three-story hillside home features multiple balconies and large windows, providing a view of the surrounding natural landscape. The structure is supported by a decked area, creating outdoor seating options. A tranquil setting is established among the greenery, showcasing the home’s elevation.
Home in Canyon Lake
4.92 out of 5 average rating, 172 reviews

Hilltop Paradise! Valley View! King & Queen beds!

Hilltop Views + Room for Everyone! Perched at the top of the hill, this 3-story getaway is all about views, space, and laid-back vibes. With 3 decks, 3 private bedrooms each with a King or Queen bed, extra beds in the Loft, a stocked kitchen, and a Game Loft for fun nights in, it's the perfect launchpad for Lake Days, River Floats, and Whitewater Amphitheater shows. Sunrise, sunset, and serious chill - this is the kind of place you’ll want to come back to.

Top guest favorite
A private heated pool is surrounded by a deck featuring a patio umbrella and comfortable seating. Scenic views of the hill country are visible in the background, with a clear blue sky overhead. The area offers space for relaxation and enjoyment.
Home in Canyon Lake
4.92 out of 5 average rating, 106 reviews

Cozy Cottage with heated pool and amazing views.

The Cozy Cottage is your ideal spot for relaxation and rejuvenation! It's nestled on a hilltop in a semi-secluded area of the Texas Hill Country. Escape to a warm, welcoming, and private, pet-friendly home offering all the comforts of cozy living. Located just minutes from restaurants, shopping, and Canyon Lake. Only 8 miles to the Guadalupe River and the Whitewater Amphitheater, and 19 miles to the charming town of Gruene. There's something for everyone!

Top guest favorite
A serene pool area is highlighted under soft evening lights, surrounded by lush greenery and decorative string lights. The water shimmers in inviting turquoise hues, while comfortable loungers are placed nearby for relaxation. A grill is positioned within easy reach, perfect for outdoor cooking.
Home in Bulverde
4.97 out of 5 average rating, 116 reviews

Hill Country LUX | Pool & Horses

Escape to a serene retreat on 8 picturesque acres, where peace and tranquility meet convenience. Despite the secluded feel, you’ll find popular spots like H-E-B, IHOP, Starbucks, Burger King, and Taco Bell just a 2-minute drive away. Enjoy easy access to local attractions, with the Guadalupe River just 15 minutes away, and New Braunfels and Canyon Lake only 25 minutes from the property. Plus, the San Antonio Airport is just a short 25-minute drive

Guest favorite
A spacious yard is covered in lush green grass and shaded by large pecan trees. The view extends towards the Blanco River, which is partially visible through the trees. Dappled sunlight creates a serene atmosphere across the landscape.
Home in Blanco
4.88 out of 5 average rating, 220 reviews

Blanco River Home - River view with new updates!

With a spacious back porch and sprawling yard with large pecan trees facing the beautiful Blanco River, this home provides a relaxing oasis for a week-end getaway or longer stay. Walk to the historic Blanco town square, stroll or picnic in the park or explore the scenic Hill Country. Enjoy the recent refresh which includes floor to ceiling windows in the living area, vinyl plank flooring throughout and updates to both bathrooms

Popular amenities for Guadalupe River house rentals

Destinations to explore

  1. Airbnb
  2. United States
  3. Texas
  4. Guadalupe River
  5. House rentals