
Pet-friendly vacation rentals in Florence County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Florence County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Kuker Cottage Downtown Florence-Near I95 & I20
Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20
WalkabilityOutdoor spacesSolo travel

Saved by Grace Retreat 2 Rustic Creekside Cabins
Escape to Saved by Grace Retreat. A private creekside retreat w/ 2 RUSTIC cabins on the quiet banks of Black Creek. Wake up to birdsong, sip coffee beneath the canopy of trees, cast a line & fish along the creek, rest in the hammocks, & enjoy God’s presence in an UNPLUGGED santuary. Whether you're looking to relax, reconnect, or explore the outdoors, Saved by Grace Retreat offers the perfect balance of comfort & simplicity. “Come away by yourselves to a quiet place and rest awhile.” -Mark 6:31
PetsOutdoor spacesIndoor spaces

The Hideaway at Fox Fields
The Hideaway at Fox Fields tiny home sleeps up to 4 with one bedroom and a sleeper sofa (both queen size beds). The bathroom has a walk-in shower. There's full kitchen with dishwasher, oven, microwave, and dishes, plus a washer/dryer combo. There's TV (guests use their own streaming accounts), game cabinet, and two mini-split AC units. The front porch overlooks a pond; cows are in the pasture at times. Located 10 minutes from I-20 Exit 137 and 5 minutes from The Cabin at Old Spur wedding venue.
Outdoor spacesPetsHospitality

Gated and Private Catholic Hermitage house
Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.
Outdoor spacesPetsCheckout

Charming Home in Florence, SC
Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.
PetsOutdoor spacesCheck-in

The Cottage at Dream Acres & Petting Zoo I-95/I-20
The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller studio space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!
Outdoor spacesPetsFamily

Quiet Townhome | King Bed | Easy I-95/I-20
Style meets Southern comfort in this West Florence gem. Sleeping up to 6, our quiet rowhome is the ultimate sanctuary after a long drive. Enjoy the luxury of a King-sized bed in the primary suite, outlets on every nightstand and a Smart TV in every room, or sip morning coffee on the private back patio. Tucked away from foot traffic yet only minutes from I-20/I-95, Florence Center, and the Florence Soccer Complex, we offer the perfect blend of total tranquility and city convenience.
PetsAmenitiesValue

Boho Private Downtown Stay Near I-95 & Hospital
Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!
Outdoor spacesWalkabilityValue

Quiet farmhouse near the beach
The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.
Outdoor spacesPetsWifi

King Bed Close to I-95
Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. ABSOLUTELY NO SMOKING OR VAPING ON OUR PROPERTY ($200 extra fee)!
WalkabilityPetsComfort

Cottage by the Pool: Close to Interstates
Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
Outdoor spacesPetsParking

Highway Oasis in Florence, Darlington & Hartsville
Welcome to this charming new house ideally situated close to both a major highway i 95 and i20 and the serene Myrtle beach, offering the perfect blend of convenience . Nestled in a great neighborhood, this residence boasts easy access to shopping center, ensuring that all your daily needs are just moments away. Very close to Florence Civic Center, 15 minutes to Buc-ee's Myrtle beach in 1 hr of a drive and shopping amenities.
PetsOutdoor spacesBackyard
Popular amenities for Florence County pet-friendly home rentals
Pet-friendly house rentals

Go With the Flo
PetsOutdoor spacesWifi

Sleeps on the Creek!
Outdoor spacesPetsAmenities

Cozy 2BR Near McLeod & MUSC | Pet-Friendly
PetsWalkabilityIndoor spaces

Peaceful cabin retreat! Collins Quarters
Outdoor spacesGetting aroundIndoor spaces

Clean Cozy Cottage near I-20 & I-95
Outdoor spacesPetsQuiet

Come Stay A While.
WalkabilityOutdoor spacesCheck-in

Home Sweet Home!
Outdoor spacesPetsBackyard

* NEW * Cozy and Clean 3B/2Bath
PetsHospitalityCheckout
Private, pet-friendly home rentals

Vintage Cottage @ I-20/I-95
Outdoor spacesPetsNearby

The Hanna Farmhouse
PetsWalkabilityLayout

Hide Away Studio Guesthouse
ParkingConditionSolo travel

Private apartment minutes from Darlington Raceway
PetsOutdoor spacesKitchen

Modern 1 bedroom condo near downtown Florence
WalkabilityPetsLocation

Home Away from Home! 1 Br & 1 Bath Apt. with Porch
Outdoor spacesWalkabilityGrill

Blu Grace Farm Apartment
PetsOutdoor spacesDecor

Private Apartment 5 Min Away From I-95 & I-20
Outdoor spacesPetsBackyard
Destinations to explore
- Myrtle Beach Boardwalk
- Garden City Beach
- Lakewood Camping Resort
- Huntington Beach State Park
- Broadway at the Beach
- Myrtle Beach State Park
- Family Kingdom Amusement Park
- Myrtle Beach SkyWheel
- Myrtle Waves Water Park
- Caledonia Golf & Fish Club
- Ripley's Aquarium of Myrtle Beach
- Murrells Inlet Marsh Walk
- WonderWorks Myrtle Beach
- Hollywood Wax Museum
- Oceanside Village
- Captain George's Seafood Restaurant
- The Bowery
- Pelicans Ballpark
- Atalaya Castle
- Medieval Times Dinner & Tournament
- Topgolf
- Wild Water & Wheels
- Broadway Grand Prix
- The Pavilion Park




