
Vacation rentals in Carlisle
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Top-rated vacation rentals in Carlisle
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RARE Spacious Treehouse & Sauna Near Des Moines
Come home to luxury in nature in this spacious, double king-bed treehouse and sleep among the stars. Expansive views of rolling hills greet you as you sip your pour-over coffee on the wrap around balcony twenty feet above ground. Rain? No problem. Tuck away on the three-season screened-in porch to watch the iconic Iowa pink sunsets. Built with special touches including stained glass and intricate woodwork, this treehouse boasts warmth throughout and is sure to be a once-in-a-lifetime get-away.
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Tom's Retreat
Tom's Retreat is the perfect place for a relaxing staycation/vacation for couples/ groups of 7. It features no-step, handicap assess ability with an abundance of desirable amenities. Located just 10-20 minutes (just off Hwy 5/65) from virtually "everywhere" you might want to visit, you may find yourself staying put in the beautiful park-like setting, enjoying the covered patio & grill, retreating to a game of chess, or feasting on a home cooked meal in the fully stocked gourmet kitchen instead.
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Tranquil Cabin Retreat Near Des Moines
Welcome to Timberlandia! Just south of the Metro, at the border of Madison & Warren counties in the Middle River Valley, the cabin is on 2 acres of shaded lawns with plenty of exploring options on 18 acres of wooded paths & walking trails. Timberlandia is a secluded tranquil getaway, but only 15 minutes from the Airport, 20 minutes from West Des Moines Jordan Creek, and 25 minutes from downtown. Our cabin is great for romantic getaways, family gatherings, festivals, retreats & wedding stays.
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Country Charm Homestead
Our farmhouse homestead retreat offers the quiet and private country space, while being conveniently located near the airport and downtown Des Moines and the Iowa State Fairgrounds. This 5400 sq ft home offers 5 bedrooms and 4 bathrooms with a 500 sq ft Master Suite that has it’s own private bathroom with a whirlpool tub. The property sits on over 2 acres with a comfortable walkout back porch with a fire pit. It is perfect for extended work trips, short term rental opportunities and groups.
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Effortless Landing near Airport & Downtown
Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in couch, local coffee, & all the amenities like fiber wifi, TV, linens, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!
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Fairground Boho Bungalow
Have fun with family or friends at this stylish bungalow. One block from the west gates of the historic fairgrounds. Less than 3 miles from the East Village in beautiful downtown Des Moines. This property allows for pets offering a fenced in backyard. Amenities include a full kitchen, dishwasher, electric range, refrigerator, propane barbecue grill, and outdoor seating. There is offstreet parking that will accommodate two vehicles as well as free parking along the street.
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The Office - Pet Friendly Duplex near Downtown!
“The Office" is a 2-bedroom, 1-bathroom Dunder Mifflin themed duplex near downtown Des Moines. It's decorated with inspiration from the TV show. The duplex has a kitchen (but no stove), a comfy TV watching area, and offers a unique and central location with a large driveway. Whether you’re a die-hard fan or have never watched an episode, the Office is designed to be a comfortable and welcoming place for everyone. Traveling with a group? Check out our adjoining Airbnb, the Rosebud!
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Unique "Little Italy" Apartment
Drive into the attached garage and go upstairs where you will find your very private entrance to a quiet, peaceful, and restful living. Located 1 mile from the downtown area on a street loaded with large Oak and Walnut trees. A huge back yard in which to stroll or barbecue. It is the top half of my house complete with it's own kitchen, bathroom, and bedroom. My residence is the bottom half of the house. Lots of excellent restaurants nearby. Check out the "Guide to Restaurants".
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8000sqft Barndo | Indoor Court + 2 Living Qtrs
Welcome to The Lodge on 3rd - a massive 8000 sq ft Barndominum. Nestled in the heart of Des Moines, Iowa, this stunning retreat offers the perfect blend of rustic charm and modern elegance. With 4 spacious bedrooms and a large loft, there is plenty of room for you and your guests to unwind in style. This property is next door to Luxury Living on Third. airbnb.com/h/luxurylivingonthird These combined properties are ideal for family reunions, etc. ***$200 Pet Fee***
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Farmhouse-ish - all the charm without the farm
Tranquil Country Retreat on 2 Private Acres Escape the hustle and bustle at our peaceful rural getaway set on two acres with panoramic country views and star-filled skies. Enjoy morning coffee on the porch and unwind by the fire pit in the evenings. Our charming country home blends rustic charm with comfort — the ideal place to disconnect and recharge, while still being just 7 minutes from downtown Carlisle and 25 minutes from Des Moines.
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Relaxing galaxy bell tent getaway
Come sleep under the stars in this cozy galaxy bell tent. You can enjoy a good nights sleep in the comfortable King bed and stay comfortable with an air conditioner and heater. There is also a fridge for keeping your food fresh. Soak up nature while you hike the trails around Oak Haven Acres, a 32 acre farm in rural Iowa. For your security we have a trail camera at the beginning of the driveway that won’t intrude on your privacy.
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New A-Frame Cabin by Des Moines (Hackberry theme)!
Escape to one of our three brand-new, fully furnished A-frame cabins at River Oaks RV Park—where modern comfort meets rustic charm. Each A-frame is uniquely designed, stylishly appointed, and perfect for making unforgettable memories. Whether you’re relaxing by the river, roasting s’mores under the stars, or just soaking in the cool, creative vibe of your private space, this family-friendly getaway is anything but ordinary.
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Popular amenities for Carlisle vacation rentals
Other great vacation rentals in Carlisle

Cozy Retreat | Steps to Yellow Banks Park Sleeps 6
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Downtown Studio w/ Private Patio + Skyline Views
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Relaxing pond house nestled in nature
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A Touch of Pleasant
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CozyHouse w/ HotTub, Sleeps 8,3BR,2BA,2LvngRms
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Convenient Townhome (3 Bdrm / 2.5 Bath)
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Payton Landing ~ Cozy Classic! Walk to DSM Airport
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Stay Awhile Cottage in Carlisle
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