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Vacation rentals in Barro Colorado Island

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Barro Colorado Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Panamá
4.93 out of 5 average rating, 136 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favorite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.94 out of 5 average rating, 16 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.98 out of 5 average rating, 80 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top guest favorite
Cabin in Penonome
4.98 out of 5 average rating, 132 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favorite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.82 out of 5 average rating, 319 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Top guest favorite
The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.
Villa in Punta Chame
4.97 out of 5 average rating, 144 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 216 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite
Home in Altos del Maria
4.76 out of 5 average rating, 145 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 228 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Superhost
Cabin in Altos del Maria
4.82 out of 5 average rating, 141 reviews

Cabin in Altos del María

Cozy cabin in Altos del María, ideal for couples looking to relax in a mountain setting. Enjoy a cold climate, surrounded by nature. It is pet-friendly and is equipped with the essential amenities: a room with a queen-size bed, sofa bed, and inflatable mattress, perfect for up to 4 people. It has a washing machine, grill, hammocks and guard post for added security. The atmosphere is conditioned to blend in with nature. Parking for 3 cars.

Guest favorite
A private rooftop terrace offers expansive views of the ocean and skyline. Comfortable seating arrangements include a coffee table and lounge chairs beneath a shaded umbrella. Decorative plants enhance the outdoor space, while string lights provide a warm ambiance during evenings.
Home in Panamá
4.92 out of 5 average rating, 162 reviews

Exceptional three-story building with sea view

This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Top guest favorite
The modern two-story cabin features large glass windows that offer expansive views of the surrounding greenery. A spacious deck with seating is visible, surrounded by lush vegetation and natural stone pathways leading up to the entrance.
Cabin in Panamá Oeste
4.9 out of 5 average rating, 199 reviews

Altos del María Cabin La Loma de Styria

Relax with the whole family at this peaceful place to stay. It is a fantastic, cool and pleasant place where you can do many ecotourism activities, the best option if you want to have one of the best views you can imagine. Great for couples too. We have 2 bedrooms on the 2nd floor and 2 bathrooms. Multiple places to take beautiful photographs

Popular amenities for Barro Colorado Island vacation rentals