House vacation rentals in Saint Louis County

A well-lit guest room features tall vaulted ceilings with exposed wooden beams and skylights. A cozy bed is adorned with patterned bedding, while decorative plants are placed around the space. Large windows allow natural light to fill the room, complemented by soft curtains.

4.9 out of 5 average rating, 440 reviews

Sunny South City Guest House

Newly-rehabbed & cozy guest house. Everything you need is located here in the historic Bevo Mill neighborhood. In the heart of south St. Louis city, you’re steps away from local businesses, including the picturesque, historical Das Bevo. Step into a vintage-styled oasis, featuring large windows with plenty of natural light, tall vaulted ceilings, comfy queen bed, unique fridge, breakfast bar, sizable bathroom with a large walk-in shower. Hang outside at the picnic table under cute string lights.

Superhost

A vibrant backyard scene is captured, featuring a refreshing pool surrounded by lush greenery and colorful flower arrangements. Comfortable seating areas are arranged nearby, complemented by decorative umbrellas and a flag waving in the breeze, creating an inviting outdoor environment.

4.78 out of 5 average rating, 108 reviews

Spacious Family Home w/ Pool & Amazing Spaces

The pool is open and guests are swimming! This pool is surrounded by gardens and entertainment areas. 2400 sqft of living space inside with multiple entertainment areas and rooms well spread out. This is the perfect house for multiple families or generations to enjoy together! The house is amenity packed and offers a stunning kitchen, as well as a vegetable garden for guests to use and save on groceries! Located in the perfect central location within 5-15 minutes of the cities main attractions!

4.97 out of 5 average rating, 663 reviews

The charming front porch features a white wicker chair and a decorative wreath, inviting relaxation. Greenery surrounds the entryway, complemented by a well-maintained lawn. A gravel pathway leads from the porch to the driveway, creating a welcoming entrance to the guest house.

Home in Saint Charles

301 Guesthouse- Historic Main street-Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

4.97 out of 5 average rating, 231 reviews

A comfortable living area features a gray sofa, patterned chairs, and a round coffee table on a natural fiber rug. Light streams through sheer curtains, highlighting the artwork of bicycles on the wall, creating a relaxed setting for guests.

Home in Kirkwood

A Kirkwood Cottage, Quaint Suburb of St Louis

Quaint cozy cottage on a “No Thru Street”. The best place to stay in Kirkwood.This was my childhood home. Only 1/2 mile to downtown Historic Kirkwood with its many shops & restaurants,Farmers Market, Kirkwood Park & Pool & Train Depot. A couple of miles to Museum of Transport,Powder Valley Nature Center & Magic House Museum is a MUST if you have children. Home has steps to entry & is 4th house from railroad tracks that are up on the hill at end of street.Close easy access to all major highways

A light-filled living room features a comfortable sofa adorned with decorative pillows, complemented by two yellow accent chairs. A glass coffee table sits atop a textured rug, with natural light entering through windows dressed with blinds. The open layout leads to a dining area in the background.

4.99 out of 5 average rating, 144 reviews

Dogtown Century home near Forest Park & Maplewood

Our historic home has lots of natural light and high ceilings. The two bedrooms are furnished with comfy queen beds. The sunroom also doubles as a third sleeping room. Enjoy a morning cup of coffee on the large front porch, or yard games and bbq in the fenced back yard. The updated kitchen comes fully equipped with everything you need to help you feel right at home. Minutes from Forest Park, BJC and SSM hospitals, universities, downtown, many great restaurants and shops. Furry friends welcome!

A light-filled living area features a neutral color palette with hardwood flooring. A comfortable sofa and armchairs surround a wooden coffee table, while a cozy rug adds texture. A fireplace and a television are positioned on the white brick wall, complemented by windows dressed in sheer curtains.

4.96 out of 5 average rating, 220 reviews

Terra House - Lafayette Square Hideaway

This charming home built in 1925 is located in a peaceful neighborhood conveniently situated just moments from Soulard, Lafayette Square, and downtown! This prime location means easy access to a variety of restaurants, bars, and entertainment! Lafayette Square Park and hip cafes are just a stone's throw away, making it ideal for those who love to explore the local scene. The perfect combination of convenience, comfort, and character, making us an excellent choice for visitors to St. Louis!

A charming bedroom features a spacious bed layered with colorful pillows and a textured throw. Brightly painted walls are adorned with an array of artwork and photographs. Natural light filters in through large windows, while a ceiling fan adds a touch of elegance to the vibrant decor.

4.99 out of 5 average rating, 121 reviews

Kalisto House: 420 Retreat w/Concierge & Hottub

Take it easy at this tranquil retreat in historic Tower Grove Heights, St. Louis. Nestled in a preserved 120-year-old flat, Kalisto House offers an immersive experience for the canna-curious to the Cannaseur. With cannabis-inspired art, a serene meditation room, and concierge service, this sanctuary invites you to explore, unwind, and connect. From personalized pairings to guided rituals, every detail is curated for an unforgettable, elevated escape. Ask about premium & bespoke experiences.

A comfortable living room is showcased, featuring a large sectional sofa and a decorative stone fireplace. Colorful stained glass windows allow natural light to filter in, while a patterned area rug adds warmth to the hardwood floor.

4.99 out of 5 average rating, 213 reviews

Sparkling Vintage Charmer, King Bed, Quiet Comfort

The Fairview is a vintage modern 2BR home in desirable North Hampton (south StL city). We've taken special care to offer a unique, memorable experience while providing the convenient, clean comfort you expect in an overnight stay. You'll have easy access to two major highways which means most StL attractions will be minutes away. (The drive to Barnes Hospital is less than 10 min.) The Fairview is nearby restaurants, coffee shops and shopping––it's the perfect place to live like a local!

The exterior of the home is shown at dusk, highlighting brick walls and well-lit windows. A small seating area with a stone table and metal chairs is visible, surrounded by gravel and scattered leaves. Outdoor lighting casts a warm glow along the pathway.

4.99 out of 5 average rating, 166 reviews

The Clementines Experience

We purchased this home in 2022 and as we work through our remodeling projects we deciding to share the home on the Airbnb app. It’s been so nice to share and assist guests visiting St Louis with recommendations. We have a strict no party rule and quiet time in the neighborhood starts at 9pm. The only individuals allowed on the property are the ones on the reservation up to a total of 6. If not followed your reservation will be cancelled and you will have to leave the premises.

A living area is featured with a modern sectional sofa positioned near large windows, allowing natural light to fill the space. A wooden dining table with chairs stands nearby, and a fireplace adds a cozy element to the room, complemented by a mirror and wall art.

4.95 out of 5 average rating, 156 reviews

Large Fenced Yard & Deck-Cozy Fam Friendly Home

**FAMILY FRIENDLY** (See details for the items avail for families) This 2 bedroom home has everything you need for a relaxing trip! Fully updated with stylish and comfortable furniture and decor. Fully equipped kitchen and an amazing backyard/deck. Quiet street by one of the best Mexican restaurants in St. Louis - Hacienda - (can walk 2 min there) Close to everything! 13 minutes to the St. Louis Zoo 10 minutes to The Magic House 15 minutes to Busch Stadium & Union Station

4.98 out of 5 average rating, 196 reviews

Entire home-King bed-2 Bedroom-Close to Everything

Kick back and relax in this calm, stylish space. Located in one of the safest neighborhoods in St. Louis, this home is just a short walk or drive from parks, restaurants, and local attractions. Take in all of St. Louis as you'll be only minutes away from everything! This beautiful, single family home is full of warm and welcoming boho chic decor. Both king and queen beds are memory foam hybrids. Fully equipped kitchen and coffee bar. Wifi, laundry, and parking are included.

Superhost

A spacious bed with a dark headboard is dressed in crisp white linens and accented with bright red pillows. Abstract wall art hangs above, adding a contemporary touch. Soft lighting emanates from a bedside lamp, illuminating the neutral gray walls.