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Vacation rentals in South Tucson

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Tucson

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson
4.97 out of 5 average rating, 499 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Tiny home in Tucson
4.92 out of 5 average rating, 179 reviews

Chic Desert Casita- Immaculate And private

Stunning Studio Casita! Custom New build with an Open floor plan, Bright and cozy and in a wonderful, walkable, Downtown Tucson Neighborhood. Walking distance to A- Mountain, Annex, Mercado San Agustin, Streetcar, The Loop bike path, UofA Campus 2.5 miles, Art & Music venues, Saguaro National Park, Restaurants and Nightlife. -Tile floors -Cathedral ceilings with Beams -Luxurious Kitchen with Quartz countertops -A/C - Queen size bed - Smart TV - WIFI -Washer/Dryer -Enclosed yard -Pet Friendly

Top guest favorite
An outdoor space showcases a ping pong table at the center, surrounded by vibrant seating areas under a gazebo. The setting includes a putting green, lounge chairs, and a backdrop of greenery. Soft lighting decorates the gazebo, creating an inviting atmosphere for relaxation and enjoyment.
Home in Tucson
5 out of 5 average rating, 125 reviews

Villa Clemente Central 1br Resort Oasis UofA Dtwn

Welcome to Villa Clemente, your peaceful desert escape in the heart of Tucson! This stylish, resort-inspired 1-bedroom retreat is perfect for solo travelers, couples, or a trio seeking comfort and convenience. Whether you're here for a campus visit, golf weekend, hiking adventure, or a restful staycation, Villa Clemente offers everything you need to relax and recharge. 1BR w/ rain shower, full kitchen, coffee bar, grill, putting green, luxe touches, near UofA, Reid Park, golf & hiking trails.

Guest favorite
The entrance of the adobe home features a covered porch framed by archways. Potted plants and cacti are placed around the entry, adding greenery to the space. A solid door is centered at the top of the steps, inviting guests inside.
Home in Tucson
4.93 out of 5 average rating, 152 reviews

Bright Historic Adobe Duplex near Downtown Tucson

Welcome to this bright historic adobe home in the center of Tucson. The home was built in the 1930s, and features thick mud adobe walls, high shiplap ceilings, and builtin features not found in modern homes. The home has been renovated with new flooring, a new kitchen, and appliances. The home also features a great covered front porch that I love to eat and read out on. Close to Downtown, University of Arizona, Starr Pass hiking and biking, and Saguaro National Park in a quiet neighborhood.

Guest favorite
Earthen home in Barrio Viejo
4.95 out of 5 average rating, 171 reviews

The Root Beer Adobe Hotel

A striking 1890's adobe dwelling located in the renowned historic Barrio Viejo district. The Root Beer Adobe Hotel is an old-world experience nestled within a collection of folk art; primitive antique interiors complimented with high ceilings, concrete, brick, and saltillo floors, all bathed in natural desert light throughout. There are three large bedrooms, a great family den, a dining room, two fireplaces, a clawfoot tub washroom, and a native garden patio with outdoor living amenities.

Top guest favorite
Home in Barrio Viejo
4.95 out of 5 average rating, 220 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Guest favorite
A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.
Guesthouse in Tucson
4.96 out of 5 average rating, 170 reviews

Adobe Carriage House downtown Chiminea+Ramada

This studio is spacious & comfortable. It is detached, secluded, on a quiet street, ample street parking and completely fenced in. The yard has a ramada with a table, chairs, string lights and a chiminea Inside, you’ll love the exposed adobe, skylight, and wood beam ceilings. The fully stocked kitchen is updated, with full size appliances. In the heart of Armory Park, it is close to 5-points, downtown, historic 4th Ave and Uof A. Ask me for dining, hiking, shopping and day trip recs!

Guest favorite
An outdoor seating area is framed by wooden pillars, featuring a black table and chairs beneath a vibrant blue umbrella. A decorative area rug lies on the ground, surrounded by potted plants, while distant shrubs provide a natural backdrop.
Bungalow in Tucson
4.89 out of 5 average rating, 739 reviews

Perfect casita Minutes from U of A & downtown!

Brand new home located near the downtown area . Minutes from all Gem shows and Kino soccer fields. Many restaurants and bars nearby. There is also a Costco, Walmart, and movie theater nearby. 24 hour post office around the corner . This home is a few minutes to the U of A. 15 minutes from the airport. Very convenient location. Parking on premises. Open 600 sq ft space with two queen beds. Kitchen, bathroom & shower. The yard is gated so you can have pets outside only, NOT inside

Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson
4.96 out of 5 average rating, 912 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite
A cozy sleeping area features a spacious bed adorned with neutral linens and decorative pillows. A brown leather chair complements the wooden bed frame, while a round mirror reflects natural light from the nearby window. Soft textiles create an inviting atmosphere.
Guesthouse in Tucson
4.95 out of 5 average rating, 196 reviews

Central Casita Minutes from UA & Downtown

Perfect for a weekend getaway or a long-term stay, our casita in midtown is fully equipped with everything you need to experience all that Tucson has to offer. 344 sq ft, this small and mighty space offers a fully-equipped kitchenette, theater-quality entertainment center, high speed wifi access, and washer and dryer access. Enjoy the spacious patio while you sip morning coffee or grill in the evening. You may find it hard to check-out of this cozy gem!

Top guest favorite
A spacious living area is highlighted by a brown leather sofa and an elegant coffee table. Natural light enters through multiple windows adorned with patterned curtains. A decorative ceiling fan and a stone fireplace add to the room's character, complemented by a small dining table in one corner.
Home in Tucson
4.96 out of 5 average rating, 255 reviews

1BR Casita on 17 Scenic Foothills Acres #9

Retreat to this peaceful 1-bedroom casita in West Foothills, set on a picturesque 17-acre property. Enjoy a king bed, AC/heat, full kitchen with RO water, icemaker, microwave, stove/oven, 65" Roku TV with 220 channels, fast WiFi, in-unit washer/dryer, and game table. ~800 sq ft of comfort and charm. Just 2 miles up Ironwood Hill Dr from Silverbell Rd, 6 miles to UofA. Impeccably clean and inviting, perfect for a tranquil escape. AZ TPT Lic 21337578

Top guest favorite
A communal patio area is highlighted by a large round table decorated with colorful tiles, surrounded by several chairs. Lush plants in various sizes provide greenery, with cacti and large blue pots contributing to the vibrant setting. Decorative lanterns hang from the ceiling, adding a touch of charm.
Guesthouse in Tucson
4.99 out of 5 average rating, 328 reviews

Saguaro Courtyard Retreat near National Park

If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Popular amenities for South Tucson vacation rentals

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  4. Pima County
  5. South Tucson