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Vacation rentals in South Tucson

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Tucson

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The exterior of the home features a modern white façade, complemented by a spacious patio area. Comfortable lounge chairs and a dining set are arranged on the patio, surrounded by desert landscaping and cacti. Large windows invite natural light into the interior.
Home in Tucson
4.98 out of 5 average rating, 121 reviews

Luxury Home In Catalina Foothills Tucson

Stunning Modern Home in Catalina Foothills This beautifully remodeled home sits on a spacious one-acre lot in the highly sought-after Catalina Foothills. Featuring 3 master suites, each with brand-new bathrooms, walking showers, and double vanities, this home effortlessly blends comfort and modern design. Ideally located, you’re just minutes from shopping, fine dining, and a 10–15 minute drive to downtown, University Ave, and 4th Avenue. Space, style, and location--all in one stunning package!

Top guest favorite
Guesthouse in Tucson
4.97 out of 5 average rating, 495 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Tiny home in Tucson
4.92 out of 5 average rating, 172 reviews

Chic Desert Casita- Immaculate And private

Stunning Studio Casita! Custom New build with an Open floor plan, Bright and cozy and in a wonderful, walkable, Downtown Tucson Neighborhood. Walking distance to A- Mountain, Annex, Mercado San Agustin, Streetcar, The Loop bike path, UofA Campus 2.5 miles, Art & Music venues, Saguaro National Park, Restaurants and Nightlife. -Tile floors -Cathedral ceilings with Beams -Luxurious Kitchen with Quartz countertops -A/C - Queen size bed - Smart TV - WIFI -Washer/Dryer -Enclosed yard -Pet Friendly

Top guest favorite
An outdoor space showcases a ping pong table at the center, surrounded by vibrant seating areas under a gazebo. The setting includes a putting green, lounge chairs, and a backdrop of greenery. Soft lighting decorates the gazebo, creating an inviting atmosphere for relaxation and enjoyment.
Home in Tucson
5 out of 5 average rating, 121 reviews

Villa Clemente Central 1br Resort Oasis UofA Dtwn

Welcome to Villa Clemente, your peaceful desert escape in the heart of Tucson! This stylish, resort-inspired 1-bedroom retreat is perfect for solo travelers, couples, or a trio seeking comfort and convenience. Whether you're here for a campus visit, golf weekend, hiking adventure, or a restful staycation, Villa Clemente offers everything you need to relax and recharge. 1BR w/ rain shower, full kitchen, coffee bar, grill, putting green, luxe touches, near UofA, Reid Park, golf & hiking trails.

Guest favorite
Earthen home in Barrio Viejo
4.95 out of 5 average rating, 171 reviews

The Root Beer Adobe Hotel

A striking 1890's adobe dwelling located in the renowned historic Barrio Viejo district. The Root Beer Adobe Hotel is an old-world experience nestled within a collection of folk art; primitive antique interiors complimented with high ceilings, concrete, brick, and saltillo floors, all bathed in natural desert light throughout. There are three large bedrooms, a great family den, a dining room, two fireplaces, a clawfoot tub washroom, and a native garden patio with outdoor living amenities.

Top guest favorite
Home in Barrio Viejo
4.95 out of 5 average rating, 220 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Guest favorite
A modern living area features a brown leather sofa placed against a white wall, complemented by a multi-colored area rug beneath. A flat-screen television is positioned on a wooden media console. Natural light enters through a nearby window adorned with blinds, giving the space a bright ambiance.
Guesthouse in Tucson
4.95 out of 5 average rating, 105 reviews

Casita Caballo

¡Bienvenido a tu refugio perfecto! Esta casa está ubicada en el corazón de la ciudad, lo que te permite acceder fácilmente a los mejores restaurantes, tiendas y atracciones locales. Disfruta de la comodidad de un diseño moderno con todas las comodidades que necesitas para una estancia inolvidable. La propiedad cuenta con estacionamiento privado, ideal para mayor tranquilidad, y un amplio espacio exterior donde podrás relajarte, organizar reuniones o simplemente disfrutar del aire libre.

Guest favorite
A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.
Guesthouse in Tucson
4.96 out of 5 average rating, 170 reviews

Adobe Carriage House downtown Chiminea+Ramada

This studio is spacious & comfortable. It is detached, secluded, on a quiet street, ample street parking and completely fenced in. The yard has a ramada with a table, chairs, string lights and a chiminea Inside, you’ll love the exposed adobe, skylight, and wood beam ceilings. The fully stocked kitchen is updated, with full size appliances. In the heart of Armory Park, it is close to 5-points, downtown, historic 4th Ave and Uof A. Ask me for dining, hiking, shopping and day trip recs!

Top guest favorite
A dining area is presented with a wooden table set for a meal, surrounded by woven chairs. Large arched windows provide views of the garden, allowing natural light to fill the space. Decorative plants and vibrant table settings add a touch of warmth.
Guesthouse in Tucson
5 out of 5 average rating, 119 reviews

Attractive Casita In Tucson

A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Guest favorite
An outdoor seating area is framed by wooden pillars, featuring a black table and chairs beneath a vibrant blue umbrella. A decorative area rug lies on the ground, surrounded by potted plants, while distant shrubs provide a natural backdrop.
Bungalow in Tucson
4.89 out of 5 average rating, 737 reviews

Perfect casita Minutes from U of A & downtown!

Brand new home located near the downtown area . Minutes from all Gem shows and Kino soccer fields. Many restaurants and bars nearby. There is also a Costco, Walmart, and movie theater nearby. 24 hour post office around the corner . This home is a few minutes to the U of A. 15 minutes from the airport. Very convenient location. Parking on premises. Open 600 sq ft space with two queen beds. Kitchen, bathroom & shower. The yard is gated so you can have pets outside only, NOT inside

Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson
4.96 out of 5 average rating, 910 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite
The exterior of the guest house displays a charming design with a shaded seating area under a red canopy. A fenced entrance and a pathway lead to the private entry door, showcasing a gentle contrast between the earthy tones of the structure and the bright blue sky.
Guesthouse in Tucson
4.92 out of 5 average rating, 105 reviews

Guesthouse Studio in Barrio San Antonio

This 300 sq ft private guest house studio offers a quiet, tucked-away stay behind our main home in Barrio San Antonio. It features a full kitchen, bathroom, AC mini-split, and dedicated workspace—perfect for work or relaxation. Enjoy free parking and nearby bike path access, ideal for exploring downtown or visiting 4th Ave’s cafes and restaurants. 1 mi to UofA 1.5 mi to Downtown 7 mi to Tucson Airport ☀️ SUMMER SALE: Enjoy 15% off all month of June!

Popular amenities for South Tucson vacation rentals

  1. Airbnb
  2. United States
  3. Arizona
  4. Pima County
  5. South Tucson