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Vacation rentals in South Tucson

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Tucson

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson
4.97 out of 5 average rating, 496 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Tiny home in Tucson
4.92 out of 5 average rating, 174 reviews

Chic Desert Casita- Immaculate And private

Stunning Studio Casita! Custom New build with an Open floor plan, Bright and cozy and in a wonderful, walkable, Downtown Tucson Neighborhood. Walking distance to A- Mountain, Annex, Mercado San Agustin, Streetcar, The Loop bike path, UofA Campus 2.5 miles, Art & Music venues, Saguaro National Park, Restaurants and Nightlife. -Tile floors -Cathedral ceilings with Beams -Luxurious Kitchen with Quartz countertops -A/C - Queen size bed - Smart TV - WIFI -Washer/Dryer -Enclosed yard -Pet Friendly

Top guest favorite
An outdoor space showcases a ping pong table at the center, surrounded by vibrant seating areas under a gazebo. The setting includes a putting green, lounge chairs, and a backdrop of greenery. Soft lighting decorates the gazebo, creating an inviting atmosphere for relaxation and enjoyment.
Home in Tucson
5 out of 5 average rating, 123 reviews

Villa Clemente Central 1br Resort Oasis UofA Dtwn

Welcome to Villa Clemente, your peaceful desert escape in the heart of Tucson! This stylish, resort-inspired 1-bedroom retreat is perfect for solo travelers, couples, or a trio seeking comfort and convenience. Whether you're here for a campus visit, golf weekend, hiking adventure, or a restful staycation, Villa Clemente offers everything you need to relax and recharge. 1BR w/ rain shower, full kitchen, coffee bar, grill, putting green, luxe touches, near UofA, Reid Park, golf & hiking trails.

Guest favorite
Earthen home in Barrio Viejo
4.95 out of 5 average rating, 171 reviews

The Root Beer Adobe Hotel

A striking 1890's adobe dwelling located in the renowned historic Barrio Viejo district. The Root Beer Adobe Hotel is an old-world experience nestled within a collection of folk art; primitive antique interiors complimented with high ceilings, concrete, brick, and saltillo floors, all bathed in natural desert light throughout. There are three large bedrooms, a great family den, a dining room, two fireplaces, a clawfoot tub washroom, and a native garden patio with outdoor living amenities.

Top guest favorite
Home in Barrio Viejo
4.95 out of 5 average rating, 220 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Guest favorite
An outdoor seating area is framed by wooden pillars, featuring a black table and chairs beneath a vibrant blue umbrella. A decorative area rug lies on the ground, surrounded by potted plants, while distant shrubs provide a natural backdrop.
Bungalow in Tucson
4.89 out of 5 average rating, 739 reviews

Perfect casita Minutes from U of A & downtown!

Brand new home located near the downtown area . Minutes from all Gem shows and Kino soccer fields. Many restaurants and bars nearby. There is also a Costco, Walmart, and movie theater nearby. 24 hour post office around the corner . This home is a few minutes to the U of A. 15 minutes from the airport. Very convenient location. Parking on premises. Open 600 sq ft space with two queen beds. Kitchen, bathroom & shower. The yard is gated so you can have pets outside only, NOT inside

Top guest favorite
A modern kitchen space is visible, featuring grey cabinetry and a white countertop with a small seating area. A bar stool is placed next to a round table. Light from a window illuminates the area, with a TV mounted on the wall in the background.
Guesthouse in Tucson
5 out of 5 average rating, 108 reviews

Modern 1 bdrm Casita in Central Broadmoor Village

Start your mornings on the front porch with hummingbirds dancing through the garden, or unwind out back beneath the shade of a palo verde tree. Inside, enjoy the airy, sun-filled vibe of a modern casita with warm southwestern farmhouse style. Just a 10 min walk along the nearby bike path brings you to local favorites like Barrio Bread, and several restaurants. Located in a quiet, central Tucson neighborhood, only 5 mins from the University of Arizona and 5–10 mins from downtown.

Top guest favorite
An inviting entrance showcases a wooden door with multiple panels, leading to a simple, open corridor. A framed artwork of a rider adorns the wall, while a cow skull adds a rustic touch above the doorway. Minimalist furnishings include a wooden bench and decorative cushions.
Home in Barrio Viejo
4.99 out of 5 average rating, 405 reviews

Barrio Viejo 1870 Adobe, KingBed, FirePit, downtwn

This unique, spacious, updated & authentic adobe is located in the historic Barrio Viejo of Tucson, nestled between downtown and Five Points. This desert Adobe has been abandoned since the 1970’s, but is now revitalized with new amenities, exposing the beautiful adobe walls and preserving the original ceilings. The fully stocked kitchen includes a gas range, dishwasher and granite countertops. Enjoy the smart TV in both the bedroom and living room. King size bed in bedroom

Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson
4.96 out of 5 average rating, 910 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favorite
The living area features a large sectional sofa facing a 65" smart TV, complemented by a dining table surrounded by black chairs. Natural light is welcomed through the open layout, and stairs are visible in the background leading to the upper level.
Apartment in Tucson
5 out of 5 average rating, 89 reviews

Modern Stylish Downtown Loft, By UofA + Foodie Hub

Secure Downtown Loft: Walk Everywhere! Modern loft in gated Flash TV courtyard between UofA (7min), Downtown (1min) & 5Points. Full kitchen, standing desk, fast WiFi, powerful AC mini-splits keep you cool. In-unit w/d, smart TVs, dedicated parking. Self check-in anytime. Walk to Convention Center, streetcar, dozens of restaurants/bars on 4th Ave & 5Points foodie scene. Perfect for remote work, campus visits, or exploring Tucson's UNESCO City of Gastronomy.

Top guest favorite
A spacious living area is highlighted by a brown leather sofa and an elegant coffee table. Natural light enters through multiple windows adorned with patterned curtains. A decorative ceiling fan and a stone fireplace add to the room's character, complemented by a small dining table in one corner.
Home in Tucson
4.96 out of 5 average rating, 255 reviews

1BR Casita on 17 Scenic Foothills Acres #9

Retreat to this peaceful 1-bedroom casita in West Foothills, set on a picturesque 17-acre property. Enjoy a king bed, AC/heat, full kitchen with RO water, icemaker, microwave, stove/oven, 65" Roku TV with 220 channels, fast WiFi, in-unit washer/dryer, and game table. ~800 sq ft of comfort and charm. Just 2 miles up Ironwood Hill Dr from Silverbell Rd, 6 miles to UofA. Impeccably clean and inviting, perfect for a tranquil escape. AZ TPT Lic 21337578

Guest favorite
Home in South Tucson
4.89 out of 5 average rating, 19 reviews

Relaxing home

Welcome to your home away from home! This bright and comfortable 4-bedroom (3Queen, 1full) , 2-bathroom house is the perfect getaway for families, groups, or anyone looking for plenty of space close to the action. Fully equipped. Located just minutes from downtown, you’ll have quick access to shops, restaurants, parks, and local attractions—while still enjoying the peace and comfort of a quiet residential neighborhood.

Popular amenities for South Tucson vacation rentals

  1. Airbnb
  2. United States
  3. Arizona
  4. Pima County
  5. South Tucson