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Vacation rentals in South Tucson

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Tucson

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson
4.97 out of 5 average rating, 492 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Tiny home in Tucson
4.92 out of 5 average rating, 165 reviews

Chic Desert Casita- Immaculate And private

Stunning Studio Casita! Custom New build with an Open floor plan, Bright and cozy and in a wonderful, walkable, Downtown Tucson Neighborhood. Walking distance to A- Mountain, Annex, Mercado San Agustin, Streetcar, The Loop bike path, UofA Campus 2.5 miles, Art & Music venues, Saguaro National Park, Restaurants and Nightlife. -Tile floors -Cathedral ceilings with Beams -Luxurious Kitchen with Quartz countertops -A/C - Queen size bed - Smart TV - WIFI -Washer/Dryer -Enclosed yard -Pet Friendly

Top guest favorite
An outdoor space showcases a ping pong table at the center, surrounded by vibrant seating areas under a gazebo. The setting includes a putting green, lounge chairs, and a backdrop of greenery. Soft lighting decorates the gazebo, creating an inviting atmosphere for relaxation and enjoyment.
Home in Tucson
5 out of 5 average rating, 113 reviews

Villa Clemente Central 1br Resort Oasis UofA Dtwn

Welcome to Villa Clemente, your peaceful desert escape in the heart of Tucson! This stylish, resort-inspired 1-bedroom retreat is perfect for solo travelers, couples, or a trio seeking comfort and convenience. Whether you're here for a campus visit, golf weekend, hiking adventure, or a restful staycation, Villa Clemente offers everything you need to relax and recharge. 1BR w/ rain shower, full kitchen, coffee bar, grill, putting green, luxe touches, near UofA, Reid Park, golf & hiking trails.

Top guest favorite
Home in Tucson
4.99 out of 5 average rating, 147 reviews

Charming Vintage Adobe Bungalow, Central Location

1937 adobe bungalow, located in the historic Palo Verde neighborhood, just minutes away from UofA, downtown, Banner Medical Center, Tucson Botanical Gardens and a few blocks from The Arizona Inn. Thick adobe walls and double-pane windows make it a quiet retreat. Enjoy the covered patio, mature well-tended desert landscape--front and back--and a private outdoor shower. Combines contemporary convenience with vintage charm, including high-end appliances and a cabinet/desk/murphy bed combination

Guest favorite
The entrance of the adobe home features a covered porch framed by archways. Potted plants and cacti are placed around the entry, adding greenery to the space. A solid door is centered at the top of the steps, inviting guests inside.
Home in Tucson
4.93 out of 5 average rating, 152 reviews

Bright Historic Adobe Duplex near Downtown Tucson

Welcome to this bright historic adobe home in the center of Tucson. The home was built in the 1930s, and features thick mud adobe walls, high shiplap ceilings, and builtin features not found in modern homes. The home has been renovated with new flooring, a new kitchen, and appliances. The home also features a great covered front porch that I love to eat and read out on. Close to Downtown, University of Arizona, Starr Pass hiking and biking, and Saguaro National Park in a quiet neighborhood.

Top guest favorite
Earthen home in Barrio Viejo
4.95 out of 5 average rating, 171 reviews

The Root Beer Adobe Hotel

A striking 1890's adobe dwelling located in the renowned historic Barrio Viejo district. The Root Beer Adobe Hotel is an old-world experience nestled within a collection of folk art; primitive antique interiors complimented with high ceilings, concrete, brick, and saltillo floors, all bathed in natural desert light throughout. There are three large bedrooms, a great family den, a dining room, two fireplaces, a clawfoot tub washroom, and a native garden patio with outdoor living amenities.

Top guest favorite
A serene courtyard is defined by shaded areas created by overhead sails. Lush greenery, including tall cacti and potted plants, surrounds the space. A seating area with metal chairs and a table is visible, inviting relaxation in this outdoor oasis.
Home in Barrio Viejo
4.95 out of 5 average rating, 219 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Top guest favorite
Guesthouse in Tucson
5 out of 5 average rating, 117 reviews

Attractive Casita In Tucson

A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Guest favorite
An outdoor seating area is framed by wooden pillars, featuring a black table and chairs beneath a vibrant blue umbrella. A decorative area rug lies on the ground, surrounded by potted plants, while distant shrubs provide a natural backdrop.
Bungalow in Tucson
4.89 out of 5 average rating, 733 reviews

Perfect casita Minutes from U of A & downtown!

Brand new home located near the downtown area . Minutes from all Gem shows and Kino soccer fields. Many restaurants and bars nearby. There is also a Costco, Walmart, and movie theater nearby. 24 hour post office around the corner . This home is a few minutes to the U of A. 15 minutes from the airport. Very convenient location. Parking on premises. Open 600 sq ft space with two queen beds. Kitchen, bathroom & shower. The yard is gated so you can have pets outside only, NOT inside

Top guest favorite
Guesthouse in Tucson
4.96 out of 5 average rating, 907 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favorite
A spacious living area is highlighted by a brown leather sofa and an elegant coffee table. Natural light enters through multiple windows adorned with patterned curtains. A decorative ceiling fan and a stone fireplace add to the room's character, complemented by a small dining table in one corner.
Home in Tucson
4.96 out of 5 average rating, 252 reviews

1BR Casita on 17 Scenic Foothills Acres #9

Retreat to this peaceful 1-bedroom casita in West Foothills, set on a picturesque 17-acre property. Enjoy a king bed, AC/heat, full kitchen with RO water, icemaker, microwave, stove/oven, 65" Roku TV with 220 channels, fast WiFi, in-unit washer/dryer, and game table. ~800 sq ft of comfort and charm. Just 2 miles up Ironwood Hill Dr from Silverbell Rd, 6 miles to UofA. Impeccably clean and inviting, perfect for a tranquil escape. AZ TPT Lic 21337578

Guest favorite
An inviting outdoor space features a cowboy swimming pool surrounded by a patio area with comfortable seating. A wooden table and stylish chairs complement the relaxing atmosphere. The walls showcase vibrant murals and string lights enhance the ambiance for evening enjoyment.
Home in Barrio Viejo
4.85 out of 5 average rating, 119 reviews

CASA ALMA /Cowboy Pool/Game Room

Your Casa in Barrio Vijeo is centrally located 5-10 minutes from the University of Arizona, vibrant downtown Tucson, and walking distance to the Tucson Convention Center. The Mountain Avenue bikeway is a hop and skip away while some of the city’s most scenic hiking and biking trails are reachable in 20 minutes. Top nearby attractions include the El Presidio Historic District, Arizona-Sonora Desert Museum and awe-inspiring Saguaro National Park.

Popular amenities for South Tucson vacation rentals

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