
Hotels in South San Francisco
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Top-rated hotels in South San Francisco
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Explore the City by the Bay! Pets are Welcome Here
Discover a plethora of attractions near the hotel's ideal location, next to San Francisco International Airport. Explore the vibrant city of San Francisco, where iconic sites like the Golden Gate Bridge, Fisherman's Wharf, and Alcatraz Island await. Visit the nearby Oracle Park for a memorable baseball game, or wander through the lush gardens of Golden Gate Park. Dive into the scientific wonders at the California Academy of Sciences, or indulge in world-class shopping and dining at Union Square.

Prime Location Union Square. Close to all
Private HOTEL room w/private bathroom, timeshare hotel property at THE DONATELLO in UNION SQUARE (sleeps 4) in the heart of San Francisco You are not obligated to attend a timeshare presentation. The front desk will require the following in order to get the room key: 1. Refundable security deposit $250 - credit card preferred Bank issued debit cards may be accepted. Sorry Chime, Netspend, Visa Gift etc are not accepted at this time for the deposit 2. Valid photo Government ID - must be 18+

Sophisticated Stay | Cable Cars Tours. Gym
Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Union Square Steps Away | On-Site Dining + Gym
Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24-hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Getaway by SF City Hall & Opera House - 50% Off
Discover the best of San Francisco from Club Wyndham Inn at the Opera, an elegant, budget-savvy gem nestled in the Civic Center. With City Hall, Opera House, Symphony Hall, and United Nations Plaza practically at your doorstep, every day becomes a cultural adventure. Savor world-class dining and chic favorites nearby. Transit takes you to iconic landmarks like the Golden Gate Bridge, Golden Gate Park, Alcatraz, and more. Enjoy all this at half the price of comparable hotels.

Hotel Room | Free Breakfast. Bay Area.
If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Near Stanford Univ + Breakfast. Kitchen. Pool.
Stay minutes from Stanford University, Google, and downtown Palo Alto at Residence Inn Palo Alto Los Altos. Enjoy spacious suites with full kitchens, separate living areas, and free Wi-Fi. Start your day with a complimentary hot breakfast, unwind by the outdoor pool, or keep up with workouts in the fitness center. Steps from shopping, dining, and tech hubs, this pet-friendly hotel offers the perfect blend of convenience, comfort, and Northern California charm.

Fun Escape | Happy Hour. Game Room. Location.
Axiom Hotel, a 4-star establishment in San Francisco's city center, is an ideal accommodation for those looking for a fun hotel to stay in during their trip to SF. It features a fitness center and a game room. Guests can also venture out to see prime attractions nearby, like Moscone Center and the Ferry Building. ✔ Fitness center ✔ Robot-delivered room service ✔ Pet-friendly ✔ Arcade games ✔ Cafe on-site ✔ Breakfast, lunch, dinner, boba and a full bar

Nob Hill Inn 1 Bedroom Apartment
This 1-bedroom apartment with a living room in the heart of Nob Hill offers the perfect blend of comfort and convenience. What makes this space special is the combination of privacy and space, featuring a separate living area for relaxation and a well-appointed bedroom for restful nights. Located in the prestigious Nob Hill neighborhood, you’ll be steps away from top San Francisco attractions, iconic landmarks, and local dining gems.

Near Montara Mountain + Free Breakfast & Parking
Tucked beside a coastal bluff in Moss Beach, Seal Cove Inn offers boutique charm just 30 minutes from San Francisco. Surrounded by cypress trees and steps from Fitzgerald Marine Reserve, this peaceful escape includes daily breakfast, free bike rentals, Wi-Fi, and parking. Explore Half Moon Bay’s beaches, trails, and shops, then unwind with wine on your private patio or by the in-room fireplace.

Donatello San Francisco Downtown Studio
This elegant resort is a quiet haven in San Francisco’s Union Square neighborhood. After spending your days touring the picturesque hills, parks, and waterfront by foot or famous cable car, step into a therapeutic hot tub or sauna before settling on the rooftop deck, cocktail in hand, to admire the city lights. Many great restaurants in the area including a highly rated on there in the resort.

King Bed at Shashi Hotel in Mountain View
Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms.
Popular amenities for South San Francisco hotels
Family-friendly hotels

1 Bed Female Dorm w/Private Bath

Minutes from Fisherman’s Wharf + Free Wi-Fi

Cow Hollow Inn

Private ensuite room with Balcony and AC

Near Oracle HQ | Free Breakfast + Full Kitchen

Petite Auberge

2 Queens | La Quinta Hayward | Go Shopping

Across Tesla Factory + Free Breakfast. Pool. Gym.
Hotels with a pool

Explore Winchester Mystery House! 2 Classy Units

Berkeley Marina Views + On-site Dining. Pool. Gym.

Downtown San Jose / King Bed Room

Hotel Nikko

Studio Suite in SF with Hot tub, Sauna & Roof Deck

Tech Meets Comfort In Sunnyvale | Restaurant

2 Queen | Lighthouse Hotel | near Gray Whale Cove

RIU Plaza Fisherman's Wharf
Hotels with a patio

Unique Hotel Inn at the Opera

(Full Bed) Room

Upscale Urban 2bd San Francisco

1 Bedroom Studio at The Donatello

Hotel at Fisherman Wharf 1 Room Sleeps 4 People

Stylish 1 Bedroom at Fisherman's Wharf!

1 King bed in boutique hotel

2 BR at Fisherman's Wharf
Quick stats about hotels in South San Francisco

Total vacation rentals
Explore 70 vacation rentals in South San Francisco

Nightly prices starting at
South San Francisco vacation rentals start at ﺩ.ﺇ331 per night before taxes and fees

Verified guest reviews
Over 480 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 50 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
60 properties have a dedicated workspace

Wi-Fi availability
70 of South San Francisco vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across South San Francisco rentals
Destinations to explore
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- Rentals with a hot tub South San Francisco
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- Pet-friendly rentals South San Francisco
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- Rentals with a fireplace South San Francisco
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- Rentals with breakfast South San Francisco
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- Rentals with a patio South San Francisco
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- Hotel rooms San Mateo County
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- Moscone Center
- Stanford University
- Golden Gate Park
- Oracle Park
- Muir Woods National Monument
- Golden Gate Bridge
- SAP Center
- Pier 39
- Mission Dolores Park
- Henry Cowell Redwoods State Park
- Twin Peaks
- University of California-Berkeley
- Six Flags Discovery Kingdom
- Rodeo Beach
- Palace of Fine Arts
- Levi's Stadium
- Winchester Mystery House
- Montara Beach
- Bolinas Beach
- California’S Great America
- Painted Ladies
- Davenport Beach
- San Francisco Zoo
- Googleplex




