
Hotels in South San Francisco
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Top-rated hotels in South San Francisco
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Urban Retreat | Twin Peaks. Restaurant
Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Union Square Steps Away | On-Site Dining + Gym
Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24-hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Studio Suite in the cultural Epicenter of San Fran
Just one block from Union Square, this resort is ideally located to explore all the San Francisco sights. Just a short walk or iconic cable car ride away from popular attractions in the Bay Area & Michelin star eateries. Covid-19: Enhanced cleaning protocols in place. • Guest checking in must be 18+ with valid ID & card for $250 refundable security deposit (credit card only) • Name on reservation must match photo ID at check-in • Valet parking on-site for $57 + tax per night

Book-filled Writer’s Alcove in the lobby
Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Studio Suite with Rooftop Lounge in San Francisco
Just one block from Union Square, this resort is ideally located to explore all the San Francisco sights. Just a short walk or iconic cable car ride away from popular attractions in the Bay Area & Michelin star eateries. Covid-19: Enhanced cleaning protocols in place. • Guest checking in must be 18+ with valid ID & card for $250 refundable security deposit (credit card only) • Name on reservation must match photo ID at check-in • Valet parking on-site for $57 + tax per night

Stay in the heart of SF! Free parking. KN
Located at the vibrant intersection of Chinatown and North Beach (aka "Little Italy"), the Royal Pacific Motor Inn is 15 minutes' walk to Fisherman's Wharf, the Financial District, and Union Square. The property is a motel, and this is our guests' favorite part of San Francisco. A free parking space is included with your reservation. We offer free WiFi, in-room coffee, private bathrooms, and a 24-hour front desk. A coin-op laundry facility is available for guests as well.

Bay Area Escape | Hotel Room. Free Breakfast
If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Near Coyote Hills Park | Free Breakfast + Kitchen
Residence Inn Fremont Silicon Valley offers a relaxing home base in one of the Bay Area’s most convenient locations. Located just minutes from shopping, dining, Lake Elizabeth, and top attractions like Great America Theme Park, this extended-stay hotel blends apartment-style suites with thoughtful hotel amenities. Whether you're traveling for business or leisure, enjoy a full kitchen, complimentary hot breakfast, outdoor pool, and 24/7 fitness access.

Monroe Studio 303
The Monroe Residence Club is a residential hotel located centrally in the heart of San Francisco with public transportation at our doorstep and local shops and businesses nearby. It is conveniently located just a block from Whole Foods, blocks from a the iconic Lafayette Park, within walking distance of several hospitals and more! The Monroe offers 24-hour front desk security, breakfast and dinner on-site, as well as common areas for congregating.

King Bed at Shashi Hotel in Mountain View
Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms. New for 2025 - daily wine tasting, yoga, zumba, and live music.

Trendy Hotel Stay at Aloft Cupertino
Join us for nightly complimentary premium wine tasting, explore the neighborhood with Philz Coffee, Voyager Craft Coffee and Whole Foods just steps away. Centrally located between I-280 and Highway 85 with convenient access to Apple, Amazon, Google, Samsung and Netflix. Near Main St. Cupertino and endless restaurant options. Make your way to our rooms and suites, with ultra-comfortable beds, walk-in showers.

Silicon Valley Inn, 1 King Bed
Fuss-free motel-style setup right off Route 82, a 5-minute stroll from Belmont train station and 3 miles from Hiller Aviation Museum. San Mateo, San Carlos and Redwood City are easily accessible via CalTrain. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12% City Transient Tax) will be charged upon arrival. A refundable security deposit of $XX will also be collected.
Popular amenities for South San Francisco hotels
Family-friendly hotels

The Suites at Fisherman's Wharf One-Bedroom Suite

Bed in 6-Bed Mixed Dorm with AC

1 Bed Female Dorm w/Private Bath

Minutes from Fisherman’s Wharf + Free Parking

Single Bed in 6 Bed Female Room

Bold, boho hideaway in the heart of the city

Walk to shops, dining, Murphy Ave & CityLine

Near Oracle HQ | Free Breakfast + Full Kitchen
Hotels with a pool

Bayfront Stay Near Berkeley Marina + Dining & Pool

Guild & Pepper bath amenities & courtyard views

Downtown San Jose / King Bed Room

Classic 2 Double Beds

Minutes to Airport | Pool + Free Breakfast

Near Santana Row & San Jose Convention Center

California Spirit | Cable Cars | Chinatown

Experience All That Silicon Valley Has To Offer
Hotels with a patio

Club Wyndham Suites at Fisherman’s Wharf

Unique Hotel Inn at the Opera

Apart-hotel@California Street, Close to Union Sq6.

(Full Bed) Room

Upscale Resort The Donatello

Upscale Urban 2bd San Francisco

Deluxe 1BD in Fisherman's Wharf

2 BR at Fisherman's Wharf
Quick stats about hotels in South San Francisco

Total vacation rentals
Explore 50 vacation rentals in South San Francisco

Nightly prices starting at
South San Francisco vacation rentals start at ﺩ.ﺇ1,249 per night before taxes and fees

Verified guest reviews
Over 250 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
50 of South San Francisco vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across South San Francisco rentals
Destinations to explore
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- Rentals with pools South San Francisco
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- Stanford University
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