
Hotel vacation rentals in South San Francisco
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in South San Francisco
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

Broadmoor Studio 429
The Broadmoor - A family-owned business since the 1960s. Step back in time and enjoy staying at a traditional residence hotel. While once a retirement community, The Broadmoor now serves many types of residents and guests. Breakfast in our restaurant is included with each night's stay. Centrally located on Cathedral Hill near Japantown and Lower Pacific Heights, all of San Francisco is easily accessible. If in need of assistance, our 24-hour front desk concierge and security are available.

Bright Studio Suite King Bed with Kitchen
Centrally located in the Silicon Valley, enjoy our spacious suite with fully equipped kitchen. Enjoy FREE breakfast, FREE wireless internet and more. Across the street from Safeway Grocery, Starbucks, Jamba Juice, many specialty shops and an array restaurants. Nearby to Levi Stadium, Shoreline Amphitheater, California's Great America, Winchester Mystery House, Twin Creeks Sports Complex, Santa Clara University, Santa Clara Swim Club, Santa Clara Kaiser and the Santa Clara Convention Center.

Rock Roulade Cocoon
Your own space/ no shared rooms, easy access ground floor and convenient location. This unique place has a fresh style all its own. Formally a secret famous recording studio for pop-rock bands, it was known as “The Hearst”. World famous records by the Killers were made here, “Hot fuss” and “Sawdust”. The first room, (now bedroom) was the control room with recording equipment and the second room (now tub room) was where the musicians played. Welcome pets for a fee if $35/per pet -per night.

SoMa 9 Residences Room 7 Shared Bath
SOMA (short for South of Market St) is top of the list for where to stay in San Francisco for the first time. SOMA 9 Residences is located in the Heart of SF SOMA District, were you'll find everything from shopping to fine dining, plus landmarks such as Yerba Buena, Moscone convention center, SF MOMA, and steps away to Giants Ballpark. The proximity to Market St. makes SOMA one of the most accessible areas of the city. There's buses and rail lines (called BART) on just about every block.

Sophisticated Stay | Cable Cars Tours. Gym
Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Elegant Noe Valley/Glen Park private suite
Elegant private suite in the Noe Valley/Glen Park neighborhood of San Francisco on a quiet, safe street convenient to transport (J Church Streetcar, 24 Muni bus, BART), restaurants and shopping. Private entrance, queen size bed, high fidelity entertainment system, private white marble bathroom w/ shower and soaking tub, private office with desk and printer; refrigerator, microwave and coffee maker. Free parking on quiet street. Ideal for couples who like to walk. Infants permitted.

San Francisco Suites Studio lV on Nob Hill
Experience true hospitality in an Edwardian setting that is filled with European paintings,antique furniture,crystal chandeliers and a full service kitchen in every suite. You can also have your coffee upstairs in the gazebo overlooking the City. In the afternoon wine,cheese and crackers are served in the lobby and sherry is offered in the evening in front of the fireplace. The concierge will make your dinner reservations and when you depart, the cable car awaits on Powell Street.

Union Square Stay | On Site Restaurant & Bar
Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24- hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Book-filled Writer’s Alcove in the lobby
Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Bay Area Escape | Hotel Room. Free Breakfast
If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

King Bed at Shashi Hotel in Mountain View
Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms. New for 2025 - daily wine tasting, yoga, zumba, and live music.

Boutique large studio in NoPa San Francisco
Self-contained large studio in San Francisco with kitchenette. Located in San Francisco's NoPa area which provides some of the best restaurants and bars in the city as well as close access to the outside spaces of the Panhandle and Golden Gate Park. The studio is located on a quiet street which is a 5 minute walk from the NoPa restaurants and Bi-Rite on Divisadero, 7 mins walk from Alamo Square and 15 mins walk from Golden Gate Park
Popular amenities for South San Francisco hotel rentals
Family-friendly hotel rentals

1 Bed Female Dorm w/Private Bath

Single Bed in 4 Bed Male Capsule Room

Berkeley Double Bed with Garden View | Indoor Pool

2 Queen Beds | Near Airport. Pool. Free Breakfast

Ideal spot next to SFO, perfect for early flights

Spot-on location for classic San Fran must-do’s

Relax Near SFO | Gym. Free breakfast & Parking

Historic Nob Hill location (iconic!)
Hotel rentals with a pool

Guild & Pepper bath amenities & courtyard views

Classic Double at Hotel Valencia Santana Row

Classic King Bed at Grand Bay Hotel San Francisco

Near Santana Row & San Jose Convention Center

Sleek, classic rooms in heart of SF

Sleeps 4 if you’re all game for sharing

Boutique stay tucked along Matadero Creek

Near Levi’s Stadium + Free Breakfast. Pool. Bar.
Hotel rentals with a patio

1 Br Ritz-Carlton San Francisco

Gorgeous Donatello Studio

Unique Hotel Inn at the Opera

Central SF Studio Perfect for Exploring the City

(Full Bed) Room

Courtyard Room with Queen Bed in Central Oakland

2 BR at Fisherman's Wharf

1 King bed in boutique hotel
Quick stats about hotel rentals in South San Francisco
Total rentals
50 properties
Nightly prices starting at
ﺩ.ﺇ1,249 before taxes and fees
Total number of reviews
250 reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with a pool
20 properties have a pool
Destinations to explore
- Northern California Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Francisco Vacation rentals
- Gold Country Vacation rentals
- Central California Vacation rentals
- San Francisco Peninsula Vacation rentals
- San Jose Vacation rentals
- Santa Barbara Vacation rentals
- Silicon Valley Vacation rentals
- North Coast Vacation rentals
- South Lake Tahoe Vacation rentals
- Monterey Vacation rentals
- Fitness-friendly rentals South San Francisco
- Apartment rentals South San Francisco
- Rentals with breakfast South San Francisco
- Family-friendly rentals South San Francisco
- Pet-friendly rentals South San Francisco
- Rentals with a fireplace South San Francisco
- Condo rentals South San Francisco
- Rentals with a washer and dryer South San Francisco
- Rentals with pools South San Francisco
- Rentals with a patio South San Francisco
- Private suite rentals South San Francisco
- Rentals with an EV charger South San Francisco
- House rentals South San Francisco
- Rentals with a hot tub South San Francisco
- Rentals with a fire pit South San Francisco
- Rentals with outdoor seating South San Francisco
- Hotel rentals California
- Hotel rentals United States
- Golden Gate Park
- Stanford University
- Oracle Park
- Muir Woods National Monument
- Twin Peaks
- Golden Gate Bridge
- Bolinas Beach
- SAP Center
- Mission Dolores Park
- Montara State Beach
- Henry Cowell Redwoods State Park
- Davenport Beach
- Six Flags Discovery Kingdom
- Pescadero State Beach
- Pier 39
- Brazil Beach
- California’S Great America
- Rodeo Beach
- Painted Ladies
- Winchester Mystery House
- Palace of Fine Arts'`
- San Francisco Zoo
- Bonny Doon Beach
- Santa Maria Beach