Some info has been automatically translated. Show original language

Guesthouse vacation rentals in Santo Domingo Este

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Santo Domingo Este

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Top guest favorite
A single-story studio is presented with a warm orange exterior and two front windows, framed by black metal bars. A gated fence and small grassy area enhance the inviting entrance, while a paved driveway provides access to the space.
Guesthouse in El Millón
4.95 out of 5 average rating, 40 reviews

Private Cozy Apartment Studio

One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.

Guest favorite
A spacious room features a full bed with crisp white linens, flanked by two bedside lamps. Decorative artwork is displayed on the walls, while a wooden desk and a chair are positioned adjacent to the bed. The original hydraulic tile floor adds character to the space.
Guesthouse in Ciudad Universitaria
4.92 out of 5 average rating, 25 reviews

Centrally located and unique colonial-style studio

Unique space in a 1930s house, with rustic-industrial elements. Elegant room with original hydraulic floor. Large patio with perimeter fence and electric gate. Centrally located, less than 3 kilometers from the Colonial Zone, 2.5 kilometers from the Central Polygon. Hospital, Laundry, Pharmacy, Malecon 1-2 blocks away. 500-600 meters from 2 subway stations, close to museums and restaurants. Updated technology. Smart speaker. Wi-Fi. TV with YouTube, Netflix, Prime Video. Double bed (full size).

Guesthouse in Santo Domingo
New place to stay

VillaMella Oasis 2bedroom2bathroom Patio Hot Water

Welcome to your Oasis in Villa Mella. Relax in comfort and luxury with a second-floor-level, 2 queen beds, 2 private baths, and a fold-out sofa. Enjoy A/C, hot water, fast WIFI, and 3 Roku TVs with Netflix. Secure smart lock entry and 24/7 on-site staff that will ensure peace of mind. Just a 5-minute walk from the Gregorio Gilbert Metro station. Bring the whole family to this great place with lots of room for fun. Need a driver? We've got you covered. Let us melt your stress away! Book now!

Superhost
A cozy bedroom is highlighted by a white bed with a bright yellow pillow. A small vase holds cheerful orange flowers, adding a touch of color to the space. Rich wooden cabinetry can be seen in the background, contributing to the room's inviting atmosphere.
Guesthouse in Santo Domingo Este
4.83 out of 5 average rating, 40 reviews

Cozy 2 BR with BBQ

This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.

Guest favorite
A lush backyard features a swimming pool surrounded by greenery and decorative elements. A barbecue grill is positioned on a stone patio, while comfortable seating arrangements invite relaxation. Colorful plants and well-maintained flower beds enhance the serene outdoor setting.
Guesthouse in Residencial Alameda
4.86 out of 5 average rating, 72 reviews

Private Oasis with Pool, Garden and Terrace.

Enjoy a private oasis designed for rest. An exclusive space with a swimming pool, large garden and terrace perfect for relaxing or sharing with the family. Ideal for those seeking tranquility, privacy and comfort without leaving the city. The property offers: - Exclusive use pool - Garden surrounded by nature - Terrace. Safe and private environment Close to supermarkets, restaurants and main roads A place to disconnect, enjoy in peace and create special moments.

A spacious studio is equipped with a cozy bed and a small dining area featuring a round red table with two chairs. A bathroom door is visible, alongside a framed artwork hanging on the wall. Blue curtains provide a pop of color against the neutral walls.
Guesthouse in Santo Domingo Este
4.67 out of 5 average rating, 30 reviews

Santo Domingo studio apartment 40 minutes from the beach.

You will have the entire apartment just for you. Enjoy the tranquility that the area offers, an ideal place to rest and work, and a strategic point to travel to places of interest You are responsible for cleaning the accommodation during your stay. It is delivered clean. If you need it, you can request cleaning service at an additional charge. The patio is rarely shared. Usually, only you will enjoy the patio. The host is in charge of cleaning the patio area.

Guest favorite
Guesthouse in Santo Domingo Este
4.75 out of 5 average rating, 12 reviews

Dorita's little house

Enjoy a quiet, comfortable and private space, where you can rest, work and get to know Santo Domingo. This home is 35 minutes from Boca Chica Beach and 15 minutes from the National District. It also has less than 5 mins. Supermarkets, plazas, clinics, fast food restaurants, recreation park, fuel station, shipping agencies and pharmacies. WE DO NOT RECEIVE PEOPLE OTHER THAN THE ACCOUNT OWNER

Top guest favorite
A bright living area features a decorative wall with a warm brick design, complemented by a wooden ceiling. A television is positioned on a simple black console, while a round dining table is adorned with a vase of elegant flowers, adding a touch of nature.
Guesthouse in El Millón
4.96 out of 5 average rating, 81 reviews

Cozy apartment for work / holidays.

Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.

Top guest favorite
The exterior of the property features a modern one-story structure with a terracotta roof. Steps lead down to a clear pool, surrounded by well-manicured hedges and lush greenery. Soft lighting highlights the entrance, offering a welcoming presence during twilight.
Guesthouse in Santo Domingo
5 out of 5 average rating, 14 reviews

Guest House w/Pool near the American Embassy

You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.

Top guest favorite
Guesthouse in Las Caobas
4.9 out of 5 average rating, 21 reviews

Your little corner of peace in SDO

Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.

Guest favorite
The outdoor area features a spacious parking lot with several vehicles, surrounded by greenery and landscaped pathways. A basketball court is visible in the background, alongside a multi-level patio area with seating for outdoor gatherings. Palm trees provide shade in this tranquil setting.
Guesthouse in Santo Domingo
4.93 out of 5 average rating, 14 reviews

U.S. Embassy Suites

Have fun with the whole family at this stylish place while taking it easy at a unique and tranquil getaway. Perfect while on the go or for appointments at the U.S. embassy. Guesthouse comes included with access to an olympic style pool, outdoor patio and barbecue grill. Great for evening get togethers and celebrations.

Guesthouse in Los Frailes
4.75 out of 5 average rating, 4 reviews

Mamuchi House apartment, Zona Franca San Isidro

2 bedroom apartment with A/C, private bathroom, 3rd floor. Ideal for you if you are looking for a comfortable space near the Free Trade Zone of San Isidro and Air Base, rest in a family atmosphere. Base rate valid for 2 people, one room.

Popular amenities for Santo Domingo Este guesthouse rentals

When is the best time to visit Santo Domingo Este?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceﺩ.ﺇ92ﺩ.ﺇ84ﺩ.ﺇ84ﺩ.ﺇ84ﺩ.ﺇ81ﺩ.ﺇ77ﺩ.ﺇ81ﺩ.ﺇ88ﺩ.ﺇ110ﺩ.ﺇ88ﺩ.ﺇ92ﺩ.ﺇ92
Avg. temp26°C26°C26°C27°C27°C28°C28°C28°C28°C28°C27°C26°C

Quick stats about guesthouse rentals in Santo Domingo Este

  • Total vacation rentals

    Explore 60 vacation rentals in Santo Domingo Este

  • Nightly prices starting at

    Santo Domingo Este vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 520 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    50 of Santo Domingo Este vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santo Domingo Este rentals

Destinations to explore