
House vacation rentals in Santo Domingo Este
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo Este
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santo Domingo Este house rentals
House rentals with a pool

Casa Grullon, an Oasis in the Colonial Zone
Incredible location, literally 20 second walk to Maraca, a great restaurant I ended up eating at twice while I was there. Corner store 30 seconds away in the opposite direction for drinks, etc. super cool architecture and pool area was peaceful. Ice cold AC in bedroom I stayed in. Few notes, city is working on the street, so must be dropped at a corner, which is only 30 seconds walk to unit. Water unexpectedly was out the last day, wasn’t the hosts fault and they were extremely accommodating and helpful. Would stay there again.

PrivatePool - BBQ - Terrace - Excelent for Big Fam
This Lacasa was a very good condition and the place the area very safe nice private pool inside look amazing is you’re beautiful to stay with your family and friend to enjoy your vacation. You won’t regret it and I will come soon. Possible for my vacation. Thank you. Let us know.

House/Santo Domingo Oeste/ POOL
Best stay i ever had in dominican republic very gracious host very attentive, polite , great prices , beautiful peaceful home , very responsive , highly recommended close to supermarkets beautiful neighborhood will 100% stay there again

Pool+Private House+A/C+Wi-Fi+BBQ, Santo Domingo
I have no complaints I enjoyed myself There's a supermarket across the street A lot of local activity In the area I would definitely return

Casa Aló:Private house with jacuzzi in the Capital
I feel at home!!! Tony and Ramona very good and nice. It's already my top 1 to enjoy with family and friends. 200% recommended!!!

Royal Villa with a swimming pool in Villa Mella SD Norte.
I loved the place, everything was very clean and organized. My friends and I really enjoyed the place and had a great time. The host was very nice and responded quickly. I would definitely come back.

House located in the center of La capital
Jenci was extremely informative. Very responsive. His home was beautiful! Definitely the perfect home to stay in.

• City Oasis • Luminous House nr Colonial Zone
The place is exactly as shown in the photos. I was in Santo Domingo for work with a group of colleagues, so we couldn't enjoy the house as much as we would have liked. However, it maintains an open and pleasant concept, the area is quiet and allows you to move easily to any place in Santo Domingo.
Weekly house rentals

Luxury Morden house with Jacuzzi Zona Colonial.!
Absolutely loved my stay in the Zona Colonial! The apartment was charming, beautifully decorated, and spotlessly clean. It’s perfectly located within walking distance to all the historic sites, cafes, and vibrant streets. Maitee was incredibly friendly and attentive, making sure I had everything I needed. The neighborhood has such a lively, authentic vibe, and I felt very safe exploring around. Highly recommend this place for anyone looking to experience the rich culture and history of Santo Domingo. Would definitely stay here again!

Casa Feliz
The best place to stand, I loved it.

Cozy & Beautiful City Center House with Jacuzzi
It is a great place to stay. I recommend it for others to stay.

BEAUTIFUL AND MODERN HOUSE
Great stay. 👍🏾

House in Santo Domingo
Everytime I'm in Santo Domingo I stay at Jormy's. I highly recommend him as a great host and his home is very nice in a very quiet safe neighborhood. 5 stars as always!

Comfort and Style
I liked the house a lot, nice and quiet area. everything was on point, Catherine is amazing host.

Penthouse Palazzo
Awesome place!!! Private terrace!!! You will love this place!!!

New - 3 Bd House Zona Colonial + Private Rooftop
It was such a beautiful house. The pictures don’t do it justice. You will love staying here. It has everything you need to enjoy your stay. It’s walking distance to shops. The rooms were so comfortable for my family of 8. We didn’t get to enjoy the rooftop terrace because we were only in the house when it was too hot. But it’s a great area to hang out.
Private house rentals

A little corner of paradise
This is my second time coming to this place and every day it's more and more beautiful and cleaner. Come, come and enjoy this beautiful place, I recommend it 100% a perfect place for everyone.

D3Freeee: BreakfastFullWifiNetflix+ComfortBed..
Great place to stay. Very clean, organized home converted into a boutique hotel/airbnb. Easy instructions. Nice area of santo domingo. I would absolutely stay here again, strongly recommended.

Luxury house in the East Zone
Very excellent place, I recommend it

Large Colonial House • Historic Center • Ideal for Groups
We have stayed with Manuel a couple of times actually I think three it’s always wonderful. The house is always great and we appreciate it. In fact will be back again soon.

Casa Escondidas is close to everything you need.
I had an amazing time staying at Ana's place. The home was beautiful and the neighborhood quiet. I felt right at home and enjoyed walking around and familarizing myself with the area. Ana was the best host, very helpful and went above and beyond to ensure my stay went well. She was always there when i had a question or issue and everything was always resolved quickly. I can't not thank her enough for her hospitality and kindness. This was the perfect home to celebrate my birthday and I hope to return and stay again. I definitely recommend this home if you're looking to be more off the beaten path and immerse yourself with the locals. You definitely won't regret it and can't ask for a better host than Ana. Thank you again for the great experience!

“Your home away from home”
What an incredible place. The host was lovely and attentive. The apartment was beautiful and well kept. The location is quiet and residential. We had a really amazing stay

Luxury house
Just excellent, I really love it❤️

Your House in the Caribbean..!
christian and his wife are very friendly the place is beautiful and clean everything is very close by. i will definitely visit there again on my next to DR.
Quick stats about house rentals in Santo Domingo Este
Total rentals
600 properties
Nightly prices starting at
ﺩ.ﺇ37 before taxes and fees
Total number of reviews
8.8K reviews
Family-friendly rentals
340 properties are a good fit for families
Pet-friendly rentals
170 properties allow pets
Rentals with a pool
130 properties have a pool
Destinations to explore
- Santiago de los Caballeros Vacation rentals
- Sosúa Vacation rentals
- Cabarete Vacation rentals
- La Romana Vacation rentals
- Juan Dolio Vacation rentals
- Bayahibe Vacation rentals
- Jarabacoa Vacation rentals
- Samana Vacation rentals
- Santo Domingo Vacation rentals
- San Juan Vacation rentals
- Punta Cana Vacation rentals
- Las Terrenas Vacation rentals
- Fitness-friendly rentals Santo Domingo Este
- Ski-in/ski-out rentals Santo Domingo Este
- Family-friendly rentals Santo Domingo Este
- Pet-friendly rentals Santo Domingo Este
- Smoking-friendly rentals Santo Domingo Este
- Rentals with a home theater Santo Domingo Este
- Rentals with a patio Santo Domingo Este
- Rentals with breakfast Santo Domingo Este
- Rentals with lake access Santo Domingo Este
- Rentals with beach access Santo Domingo Este
- Beachfront rentals Santo Domingo Este
- Rentals with a fireplace Santo Domingo Este
- Waterfront rentals Santo Domingo Este
- Kid-friendly rentals Santo Domingo Este
- Rentals with a sauna Santo Domingo Este
- Apartment rentals Santo Domingo Este
- Rentals with pools Santo Domingo Este
- Rentals with a washer and dryer Santo Domingo Este
- Serviced apartment rentals Santo Domingo Este
- Rentals with an EV charger Santo Domingo Este
- Guesthouse rentals Santo Domingo Este
- Hotel rentals Santo Domingo Este
- Rentals with outdoor seating Santo Domingo Este
- Rentals with a fire pit Santo Domingo Este
- Loft rentals Santo Domingo Este
- Rentals with an accessible height bed Santo Domingo Este
- Rentals with a hot tub Santo Domingo Este
- Villa rentals Santo Domingo Este
- Condo rentals Santo Domingo Este
- House rentals Santo Domingo Province
- House rentals Dominican Republic
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do Santo Domingo Este
- Things to do Santo Domingo Province
- Things to do Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Art and culture Dominican Republic
- Food and drink Dominican Republic
- Tours Dominican Republic