
Mansion vacation rentals in Santo Domingo
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Santo Domingo
Guests agree: these mansions are highly rated for location, cleanliness, and more.

Casa Pantheon Luxury Colonial House
Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED

Beautiful Modern Penthouse close to Zona Colonial.
Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 4 smart TVs and much more. Smart lock for easy check-in.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Luxury Penthouse With Jacuzzi
Come and decompress into your private oasis retreat. This penthouse features 4 bedroom, 3 bath, fully equipped kitchen, and calming jacuzzi. Immerse yourself in panoramic views from rooftop terrace. We are located in one of the best residential area in Santo Domingo Este. Just 15 min. from Las America International Airport, and 20 min. from beaches. Nearby you will also find great restaurants, bars, supermarket, shopping centers and pharmacies. Book now for the utmost Dominican Experience!!

'Casa de Papel' Luxurious VILLA
Discover the ultimate party getaway at Villa Fiesta Oasis! This luxurious 4-bedroom villa offers everything you need for an unforgettable stay: a sparkling pool, a relaxing jacuzzi, and ample space for entertaining. Located just minutes from the airport, convenience and comfort come together in this stunning retreat. Whether you're hosting a celebration or simply seeking a relaxing escape, House of Cards (Casa de Papel) is your perfect destination. Experience the best of Santo Domingo!

Casa del Orfebre, circa 1525
Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.

Luxury apartment in Piantini, Santo Domingo.
This elegant and spacious accommodation is ideal for families and couples who require medium or long stays. It is located in the heart of Piantini in a building with only one apartment per floor on a very quiet street, equipped with a BBQ and all the luxuries and details you can imagine. All spaces have high-speed internet and state-of-the-art TVs. The kitchen includes luxury appliances, a wine cellar, and everything you need for an elegant dinner for eight people.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Paradise Luxury Penthouse With Private Jacuzzi
Apartamento cómodo y limpio en una area segura. Ubicado en la avenida España. A solo 20 minutos del aeropuerto, 25 minutos de la playa boca chica y 15 mins de la zona colonial. Cuenta con multiple opciones de restaurantes, bars, mixers, supermercado, farmacias, bodegas o colmados y mas a solo minutos. Aire acondicionado en cada dormitorio siempre que haya energía eléctrica, de no haber contamos con abanicos movidos por un inversor.

Penthouse | Top View | Jacuzzi | Near BlueMall
Modern 3-level penthouse with 5 bedrooms, 7 beds and panoramic city views. Located in Evaristo Morales, walking distance to Gold’s Gym, Smart Fit, supermarkets, restaurants and BlueMall/Acropolis. Perfect for families and groups, offering spacious social areas, balconies, fast WiFi and private parking. Minutes from main attractions like Mirador Sur, Parque Iberoamérica and the best dining spots in Santo Domingo.

Domus Santa Barbara Sleeps 8
In the heart of the colonial zone, a 17th-century house, remodeled while preserving the characteristic colonial style, a stone's throw from Plaza de Espana and the Atarazanas Museum. Ideal for groups, Domus Santa Barbara consists of four apartments around an incredible pool, which is for the exclusive use of our guests. Enjoy an unforgettable stay in a space designed for relaxing and sharing.

Villa Francisco RD, (15min Airport) Chef Included.
Do you want to disconnect and enjoy nature? This modern, welcoming apartment is ideal for a weekend with the whole family and will make you feel at home. Enjoy one of the best outdoor spaces by the pool, where you can prepare a delicious barbecue while relaxing and soaking up the sun. 15 minutes from Aeropuerto de las Americas (airport) and 12 minutes from downtown.
Popular amenities for Santo Domingo mansion rentals
Luxury mansion rentals

Santo Domingo, Available for events and day trips

Luxury House Pool + Jacuzzi + AC + Wifi @Colinial Zone

Three Harmony Condos in the Same Building@Pool•Gym

7 Rooms/Beds and 1 Sofa Bed. Free Breakfast

FIXIE Lofts: Elegant Colonial Villa with Pool

✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL

8 Bedroom Penthouse • Private Jacuzzi • Pool Table

® {Acqualina's ~ Views} @ DowntownSD + 4BR Penthouse + Pool
Pet-friendly mansion rentals

villa yaya

Beautiful and comfortable house in the Colonial City

Spacious 4BR pool house with private parking

Villa oasis

El Retiro Villa, San Antonio de Guerra.

MirResidence(Villa, BBQ, Cinema, Picuzzi, Terrace)

Luxe 4 Bedrooms, Pool, King Beds

House in the city with an oceanfront swimming pool
Mansion rentals with a pool

Bonita villa RD

VillaRosario-Resort-Pool-Wifi-BBQ-NearBeach-Relax

elpapi_new_ny_vacation_home

Villa Sabrina

PENTHOUSE WITH PICUZZI PRIVATE 4 BEDROOMS

House located in the center of La capital

Spacious Villa for large groups with Private Pool

Villa Flor, Las Americas
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