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Vacation rentals in Santiago Canyon

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santiago Canyon

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Lake Forest
5 out of 5 average rating, 61 reviews

Private Retreat*Pool* Spa*BBQ*A/C*Disney 20 mn*TVs

VERY CLEAN! PERFECT RETREAT FOR COUPLES OR SMALL FAMILIES: - 24-Hour Self Check-In - Private Entrance/No Shared Spaces - Free Private Parking - Pool/Spa/Clubhouse - Private Backyard w/BBQ - Living Room, Bedroom, Kitchen, Full Bath - Private Washer & Dryer - High Speed Wi-Fi - 2 TVs w/ Netflix, Hulu, Sling - Full Office Workspace - DISNEY - 25 min - JOHN WAYNE AIRPORT - 20 min - LAGUNA BEACH - 20 min - LONG BEACH - 30 min - LA/HOLLYWOOD - 75 min - SAN DIEGO - 90 min - IRVINE SPECTRUM - 10 min

Top guest favorite
A spacious bed with a decorative pillow is positioned in the room, with natural light streaming in through open glass doors. A private deck with lounge seating and lush greenery is visible, creating a serene connection to the outdoor space.
Guest suite in Murrieta
4.99 out of 5 average rating, 599 reviews

Soft Air...A Luxury suite with a view!

'Soft Air' is becoming a destination in itself. A getaway surrounded by nature, this Murrieta luxury suite in Temecula Valley overlooks an oak filled canyon... fresh ocean air! Close to wineries, your own private exterior entrance, king size bed, fireplace, large bathroom with soaking tub & shower...comfort & atmosphere. An exquisite experience! Enjoy the wonderful view from your own private spacious deck complete with a relaxing swing and outdoor kitchen. First morning breakfast included.

Guest favorite
A stone archway frames a view of rolling hills and mountains. The scene showcases a wooden deck extending outward, with greenery visible in the foreground and a clear blue sky above. The natural landscape emphasizes the tranquil setting of the getaway.
Home in Temecula
4.89 out of 5 average rating, 207 reviews

2Bedroom 2bath in-law unit with kitchen and washer

Take it easy at this unique and tranquil getaway, situated in an organic citrus farm on a 27-acre private land with mountain and valley view of citrus and avocados groves. This unit has its own private entrance and a private deck with outdoor sink, BBQ and dining area. The indoor living space is about 960 sf, and the deck area is about 800 sf. The house is powered by solar array and Tesla batteries, so we won’t have a blackout even during power outages as long as not a lot of AC being used.

Top guest favorite
Home in Old Towne
4.95 out of 5 average rating, 61 reviews

A Little Shangri-La Close to Chapman U & Disney

Welcome to “Little Shangri-La, “ a studio at a historic home in Orange Plaza. Steps to Chapman University , Dining & Boutiques. The Studio has kitchenette and spacious outdoor area for dining Alfresco . Enjoy your morning coffee on your private patio . Only 6 miles to Disneyland, 20 miles to Newport Beach, 35 miles to Downtown LA, and 90 miles to San Diego. A peaceful, central escape with charm, comfort. Separate driveway parking underneath the shade of the 100 year old Avocado Tree.

Top guest favorite
An outdoor seating area is set beneath a covered deck, featuring a cozy sofa and two armchairs arranged around a coffee table. A patterned area rug brings warmth to the space, with panoramic views visible through the railing.
Guesthouse in Fullerton
4.96 out of 5 average rating, 583 reviews

Aviary with Amazing Views!

Perched on a hilltop with Amazing Views, Our place is walking distance from CSU of Fullerton and Fullerton Arboretum. We are located off the 57 fwy and a 20 min drive to Disneyland! It is a tiny cottage with modern amenities and although the cottage is detached from the main home, there is a cottage directly below, where you may hear noise if occupied. You may never see us, but available if needed. Enjoy a tranquil space with sounds of morning birds, outdoor fountains and a dog!

Top guest favorite
Tiny home in San Juan Capistrano
5 out of 5 average rating, 25 reviews

Coastal Tiny Home Retreat w/ Fire Pit-near town

Charming Tiny Home lovingly known as the Swallows Nest in San Juan Capistrano Please reach out for specific dates needed. 30 day rental. Enjoy a relaxing stay in this thoughtfully designed tiny home in beautiful San Juan Capistrano. Take a fun bike ride to historic downtown and the new River Street, filled with great restaurants and shops. Just minutes from local beaches, this cozy retreat is the perfect home base for a coastal getaway, weekend escape, or peaceful reset.

Top guest favorite
A serene bedroom space is seen, featuring a spacious bed with a simple white quilt set and neatly arranged towels. Natural light pours in through large windows, showcasing a view of lush garden greenery and colorful flowers outside.
Guesthouse in Fullerton
4.94 out of 5 average rating, 79 reviews

The OC View for You!

Note: Our pricing INCLUDES ALL FEES! No surprises! “Super Host!” Top 2% Guest Favorite! City lights views; fully stocked, light bright guest home. Spectacular sunsets! Quiet upscale neighborhood with hiking/biking trails, beautiful park, golf, ecclectic shopping and restaurants all nearby. Disneyland, Knotts, Convention Center, Angels, trains, beaches, mountains! OC Central yet peaceful location feels exclusive on top of the world! Adjacent parking/ Easy entry

Top guest favorite
Treehouse in Running Springs
4.98 out of 5 average rating, 59 reviews

Iconic A-Frame Epic Views, BBQ, Firepit, Stargaze

Before Bryan Cranston was Breaking Bad, he was chilling in this iconic Mid Century A-frame cabin in Running Springs! Here's your chance to enjoy the old stomping grounds of this Hollywood icon. This unique stay has history & charm all its own! ✔ LuluBelles Coffee House (5 min, 2 miles) ✔ Lake Arrowhead (6 miles west) ✔ Big Bear Lake (15 miles east) ✔ Iconic 1960's Floating Staircase ✔ Mid-Century Preway Fireplace ✔ Three Levels of Decks ✔ Fire pit ✔ Flat Grill BBQ

Guest favorite
A serene bedroom is framed by sheer white drapes, revealing a view of a garden through a wooden door. The spacious bed is adorned with crisp white linens and a bouquet of vibrant flowers. Nearby, a cozy seating area features warm wood tones and soft textures.
Cottage in San Juan Capistrano
4.91 out of 5 average rating, 270 reviews

Historic Cottage – Casa Mia

Exceptionally charming Cottage & Courtyard to celebrate with loved ones in the oldest neighborhood of California, yards from the Mission, River Street Marketplace, Playhouse, petting zoo, train depot, many fine restaurants, and shopping experiences all in the heart of town! Inquire within for onsite gatherings requiring a separately signed agreement from this reservation. May combine with adjacent Cottage. Quaint, cozy, and uniquely appointed.

Guest favorite
The exterior of a villa is framed by lush greenery and palm trees, showcasing natural textures. A wooden gate opens to a cobblestone pathway leading toward the entrance. Sunlight filters through the trees, creating dappled shadows across the well-maintained garden.
Guesthouse in Silverado
5 out of 5 average rating, 33 reviews

Romantic House

Casa Romantica is a hidden gem nestled in the picturesque foothills of Orange County on the Rancho Las Lomas private estate and event venue. This charming and tranquil one-bedroom, one-bath villa has a full kitchen, living room with pull-out couch and private patio area immersed in the natural surrounding . This enchanting retreat is surrounded by hiking trails, scenic drives and historic establishments. Book your getaway today!

Guest favorite
Guesthouse in North Tustin
5 out of 5 average rating, 13 reviews

Unbeatable Views - 15 min Disney! 2 br w/ Patio

Enjoy 2000 sq ft of spacious modern architecture, tons of amenities for large groups *KEY FEATURES* + Epic panoramic view of Orange County + Floor-to-ceiling glass walls + Indoor/outdoor living - glass walls that open to patio + Fully stocked kitchen + Top quality memory foam beds, gel pillows, and sheets + Speedy wifi + Smart TVs *LOCATION* + 15 min to Disneyland + 18 min to Knotts + 20 min to the beach + 15 min to Outlets

Top guest favorite
A remodeled studio space features a large bed with a geometric patterned blanket. A kitchenette is visible in the background, equipped with modern appliances. A dining table is set for two, and the space is well-lit by overhead lights and natural light from nearby windows.
Guesthouse in Orange
4.94 out of 5 average rating, 442 reviews

Studio Near Disneyland With King Bed

Large remodeled Studio near Disneyland & Anaheim Convention Center, Anaheim Honda Center/Stadium, UCI Medical Center, Chapman University, Orange circle. A very high end Serta CalKing size bed. Full kitchen. Private bathroom. Easy access to freeways. Closed to Target, restaurants, In and out bugert and super market. Nice and quiet neighborhood. Free parking. Watch 4th of July fireworks from your suite. Two nights minimum.

Popular amenities for Santiago Canyon vacation rentals