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Vacation rentals in Santa Cruz Mixtepec

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Top-rated vacation rentals in Santa Cruz Mixtepec

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A vibrant garden blooms with pink bougainvillea and lush greenery, leading to the rustic facade of the Hacienda. The charming red iron front door is framed by the tranquil landscape, with mountains rising in the background under a clear blue sky.
Home in Tlacolula de Matamoros
4.98 out of 5 average rating, 60 reviews

Nature Lover's Paradise

Our fully restored Hacienda is peaceful, private, and beautiful. 45 mins. from Downtown Oaxaca, Hacienda Don Pedrillo awaits you to dive into the Oaxacan way of life. Minutes from Tlacolula's market, Mitla's ruins, mezcal distilleries in Matatlan, Hierve el Agua. Built in 1643, you’ll enjoy all the private trails. This is a comfortable respite after a day of exploring sites, cultural experiences, and outdoor adventures nearby. Fabian is available to drive. We're here to support you!

Guest favorite
An inviting lounge area features a spacious built-in sofa adorned with colorful cushions. Large windows offer a view of the surrounding greenery, while rustic wooden beams highlight the ceiling. A circular table with dark leather chairs completes the cozy atmosphere.
Home in San Pablo Etla
4.92 out of 5 average rating, 98 reviews

Casa Labra - Labra House Etla, Oaxaca

Beautiful, secluded, surrounded by a natural preserve on all sides rustic and chic well equipped country house with gorgeous terrace, splendid mountain views and a lovely pond. Great for bird watching, hiking, cooking,meditation and focused working. Enjoy our terrace with living room dining room and a beautiful set of hamaca and hanging seat to keep you fresh on a warm afternoon, or relax in our inside lounge and living room. Wifi speed 100 mb, free parking 4700m garden 2 rooms. 2 bathrooms.

Guest favorite
The spacious living area is characterized by warm tones and textured walls, featuring an inviting sofa next to a striking coffee table. A kitchenette, adorned with simple cabinetry, includes essential appliances. Lush plants are positioned throughout, enhancing the tranquil ambiance.
Apartment in Oaxaca Centro
4.94 out of 5 average rating, 151 reviews

Magical Restored house, KS Bed/AC in Oaxaca heart

📍A solo 3 cuadras de Santo Domingo y del Andador Turístico. Recorre caminando los mejores restaurantes, cafeterías, museos, galerías y bares de Oaxaca. ✨ Casa recién restaurada que fusiona diseño contemporáneo con la esencia oaxaqueña. ✔ Cama King Size con colchón memory foam ✔ Aire acondicionado ✔ Cocina totalmente equipada ✔ Amplia sala y comedor En CASA Espíritu Fuego disfrutarás comodidad, diseño y una ubicación privilegiada para descubrir la ciudad a pie, nos vemos pronto en Oaxaca. ✨

Top guest favorite
A traditional adobe house features a terracotta roof and a welcoming porch. Surrounding gardens showcase various cacti and greenery. A winding gravel pathway leads to the entrance, while a staircase on the side provides access to the upper level of the home.
Home in Tlalixtac de Cabrera
5 out of 5 average rating, 26 reviews

Altar of the Mountains

This traditional Oaxacan house, that has four beds, was handcrafted by local artisans in exquisite adobe walls, a shading porch, furnishings and decor. It nestles in gardens of trees and blooming succulents. Guests enjoy multiple level terraces, hammocks, an outside dining area, a 22-meter lap pool and spectacular mountain views. We are in a Zapotec town with nearby restaurants and have easy transportation to Oaxaca city (20 minutes). We offer tours to villages and archaeological sites.

Guest favorite
A serene temazcal room is featured, showcasing curved stone walls gently illuminated by candles. A small potted plant and a decorative drum are placed within the space, creating a calming atmosphere. The room is designed for relaxation and holistic experiences.
Home in Oaxaca
4.92 out of 5 average rating, 226 reviews

Casa MaryFer

Casa MaryFer is located 1.5 km from Oaxaca City's International Airport and 10.3 km from the city's Zócalo and Santo Domingo church. What sets it apart is that it is located in the tranquility of a picturesque village, as well as the friendliness of its people and their traditions. The Mexican-style decoration offers its guests the comfort and friendliness of "being at home", in addition to having a temazcal bath for 6 people and therapeutic massages (at an extra cost and by appointment).

Top guest favorite
A spacious bedroom features natural stone walls and a smooth concrete ceiling. A large bed is centered in the room, flanked by two simple wooden nightstands. Comfortable seating is provided by two chairs, and a unique wooden table sits prominently in the middle of the space.
Home in Oaxaca Centro
4.98 out of 5 average rating, 95 reviews

La Danta Chayote

La Danta, a Garden retreat within the city center of Oaxaca. Stay in one of four incredible bungalows situated in the heart of Oaxaca, with access to all the best restaurants, museums and sights just walking distance from your front door. You will be staying inside an incredible Garden built over 30 years ago inside the aqueduct that brought water to the city. The bungalows are hand carved Cantera stone emulating the aqueduct, a unique experience surrounded by the incredible garden.

Top guest favorite
An open-concept living space features natural light streaming in through expansive glass doors. A mix of comfortable seating, including a sofa and armchairs, is arranged around a low coffee table. Wooden shelving displays various artworks and plants, creating a harmonious connection with nature.
Home in Reforma
5 out of 5 average rating, 69 reviews

Alcalá 226, An architectural gem

Nestled in the heart of Oaxaca, our 4-bed, 4.5-bath haven is a true embodiment of architectural brilliance, Curated by the owners of LA's iconic Guelaguetza. Each room narrates a story of elegance and comfort. Step onto the upstairs terrace for breathtaking views, or uncover the secret mezcal room curated with one-of a kind mezcales from the region. Immerse in a Oaxacan experience where modern luxury intertwines with rich cultural heritage. Welcome to your Oaxacan retreat!

Guest favorite
The exterior area is illuminated at night, showcasing a tranquil pool in the foreground. A covered wooden porch with seating is visible, surrounded by vibrant greenery and the trunk of a large tree. Soft lighting casts a warm glow across the space.
Home in Oaxaca Centro
4.98 out of 5 average rating, 115 reviews

Casa Verde Pool AC & Garden in Historic Center

Designed by Francisco López. It is a restored and improved construction to accommodate visitors who want a natural Oaxacan experience in the historic center. It has a spectacular garden with a pool that will allow you to enjoy peaceful days. Its strategic location allows you to be just a few steps from the most interesting sites. It has premium amenities and air conditioning in its bedrooms to work efficiently or to rest. To be your home in Oaxaca!

Top guest favorite
A bungalow is set against a backdrop of rolling green hills under a cloudy sky. The structure features a combination of stone and metal elements. Surrounding grasses and agave plants contribute to the natural landscape.
Place to stay in Tlalixtac de Cabrera
4.97 out of 5 average rating, 152 reviews

Bungalow at the foot of the Oaxacan mountain

Bungalow for one or two people. One bedroom, bathroom and equipped kitchen. Located in Tlalixtac de Cabrera, ten kilometers from the city of Oaxaca, at the foot of the mountains where the Sierra Norte begins. It borders an area protected by the existence of animal species: deer, hares, coyotes and others. Its location allows for hiking and mountain biking. Ideal for rest, reflection, creativity and for reuniting with yourself and the universe.

Guest favorite
Apartment in Oaxaca Centro
4.96 out of 5 average rating, 46 reviews

Charming apartment 10 minutes from downtown

CUISHE Apartments "Espadín" Apartment Brand new accommodation, with beautiful decor and design, enjoy the simplicity of this quiet and centrally located top floor apartment. It has a prime location, head to downtown and tourist walk just 8 blocks from the accommodation, convention center, museums, craft shops, markets, restaurants, etc. This place is strategically located: it will be very easy to plan your visit!

Top guest favorite
Casa particular in Oaxaca Centro
4.95 out of 5 average rating, 185 reviews

House of Miracles

Casa de los Milagros is the perfect spot for any traveler looking for privacy right in the heart of Oaxaca. Offering only three rooms, each with private bathrooms, daily cleaning for free, in a beautifully restored colonial home, it provides incomparable intimacy and service. We offer massage, temazcal, and tours. It's a great choice for families and groups. We also offer breakfast with an extra charge if you wish.

Guest favorite
Loft in Santa Lucía del Camino
5 out of 5 average rating, 10 reviews

Que ma ra vi lla en Marijo!

Located on the rooftop of our home, this charming apartment is the ideal retreat for one couple or up to three people looking for rest and privacy in Oaxaca. Enjoy wonderful views of the Cerro de Oaxaca, unforgettable sunsets and an atmosphere full of calm. Every detail is designed for you to live a comfortable and special stay. A loft for perfect rest and relaxation

Popular amenities for Santa Cruz Mixtepec vacation rentals

  1. Airbnb
  2. Mexico
  3. Oaxaca
  4. Santa Cruz Mixtepec