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Vacation rentals in Santa Clara, Panama City

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Top-rated vacation rentals in Santa Clara, Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.
Condo in Panamá
4.97 out of 5 average rating, 129 reviews

The Spot Panama - Comfy, great view & much more

Ideally located in Panama City Panama 🇵🇦 we're just 15-20 minutes from Tocumen Airport 🛩 . Approximately 10 minutes from Albrook Mall, SoHo Mall, Alta Plaza, Multiplaza and much more! Enjoy easy access to supermarkets and restaurants!. Experience peace of mind with 24/7 security and outstanding facilities: pool, gym, and free parking! More than a stay, it's a chance to shop, unwind, and soak in Panama City views. Don't hesitate- Book instantly or contact us if you have any questions.

Top guest favorite
Apartment in Costa del Este
4.9 out of 5 average rating, 10 reviews

Modern Furnished Studio with Ocean Views in Panama

Discover elevated living in Costa del Este with this modern studio at Arcadia Condo Suites—where comfort meets convenience. Designed to cater to business travelers, families, or couples, this spacious and contemporary home offers the perfect balance of comfort and sophistication for both work and leisure. - Bright and spacious 70 m² studio - Partial views of the Pacific Ocean and surrounding cityscape - Fully equipped, modern kitchen - Pet-friendly accommodations - 24/7 concierge service

Guest favorite
A comfortable sleeping area is presented with a spacious bed covered in a soft, patterned blanket. Lively artwork featuring tulips adorns the wall above, while bedside tables with lamps provide gentle illumination. Dark curtains frame the window, and air conditioning is installed overhead.
Loft in Panama
4.94 out of 5 average rating, 51 reviews

Modern apartment 20 minutes from the airport

Comfortable and cozy apartment on Av. la Pulida, 8 minutes from the Cincuentenario metro station. For business travelers and couples, this apartment features a bedroom with a full bed, a TV in the room, a full bathroom with hot water, a fully equipped kitchen, a living-dining room, a Smart TV, air conditioning, a laundry room, and a closet. It's just 8 minutes from the metro station and offers easy access to any point in the city. Centrally located, yet quiet. Enjoy a perfect stay!

Superhost
A panoramic view of the Panama City skyline is displayed, showcasing a lively urban landscape at dusk. The dark water reflects city lights, while notable icons for air conditioning, kitchen amenities, and WiFi are presented prominently, representing essential features of the accommodation.
Apartment in Panamá
4.86 out of 5 average rating, 28 reviews

Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá

✔️ SuperAnfitrión Verificado ¡Tu estadía estará en las mejores manos! Apartamento en Panamá, Panamá 📍Excelente ubicación 🏡 Espacio limpio, cómodo y seguro. 💬 Estoy disponible para ayudarte durante toda tu estancia. 🔑 ¡Reserva hoy y siéntete como en casa en Panamá! 👨‍👧‍👧 Ideal para todo tipo de turista El apartamento ofrece: 🌐 Wifi 📺 TV 🍳 Cocina 💻Zona de trabajo 🌬️Aire acondicionado 🚗Estacionamiento 🌸Lavadora 🧖‍♂️🧖‍♀️ducha con agua caliente

Top guest favorite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.96 out of 5 average rating, 127 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favorite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Apartment in Panamá
4.94 out of 5 average rating, 108 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 127 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Superhost
The living area features a light blue accent wall and a cozy gray sectional sofa accompanied by a round ottoman. A large window with striped awnings allows natural light to fill the space. Wall art and a small shelf with a clock add functional decor.
Apartment in Distrito de Panamá
4.76 out of 5 average rating, 17 reviews

Hippodrome Suites

Hippodrome Suites is located in a safe gated community in the suburbs of Panama City, just a short drive 🚘 from the Tocumen International Airport (✈️PTY), Santa Maria and Costa del Este Budiness District. City views, 24-hours security and covered parking. It is ideal for resting and working, business trips or layover nights. This condo offers a perfect mix of comfort, convenience, and tranquility.

Top guest favorite
A spacious living area is highlighted by large windows that offer views of urban high-rises and the distant ocean. A soft, rounded sectional sofa and a plush armchair provide comfort, while a dark area rug anchors the space beneath a sleek coffee table.
Apartment in Costa del Este
5 out of 5 average rating, 21 reviews

Elegant Apt in Costa del Este. Premium Amenities

Enjoy a luxurious stay in our modern design apartment located in the exclusive Costa del Este area. It has a room with a private bathroom, a cozy living room, and a fully-equipped kitchen. Building facilities include a state-of-the-art gym, swimming pool, and co-working space ideal for remote work. Perfect for extended stays, combining comfort and convenience in the heart of Panama.

Guest favorite
A cozy living area is illustrated with a modern television positioned on a wooden console. A dining table with a simple setting is visible, accompanied by dark-colored chairs. Light-colored tiles cover the floor, and a clock is mounted on the wall, providing a functional accent.
Apartment in Panamá
5 out of 5 average rating, 12 reviews

Cozy, downtown and accessible

Enjoy the simplicity of this cozy and centrally-located place. Fully equipped and close to everything (transportation, supermarket, parks, restaurants). Rest in pleasure and tranquility, after a day full of activity in the wonderful city of Panama. It has TV, Internet, air conditioning, 1 luxury bathroom, hot water, top-notch white line with internal laundry and parking.

Guest favorite
Guesthouse in Panama City
4.9 out of 5 average rating, 232 reviews

Boho Studio-Private Terrace near the airport

Perfect for 1–2 guests, Wifi, quiet terrace, separate room, has A/C, and a small bathroom. Located near Tocumen International Airport, 10 to 13 minutes by car. The Studio is Close to 2 Shopping Centers, Metromall and Los Pueblos. The residential area is safe to walk, organized and clean streets. We have the Cerro Viento Metro station outside in Metromall.

Guest favorite
Apartment in Costa del Este
5 out of 5 average rating, 7 reviews

2BR Apartment Panama Costa del Este

Enjoy the perfect combination of style and comfort in this elegant apartment with two bedrooms and two full bathrooms, ideal for families, executives, or small groups. Located in Costa del Este, one of Panama City's most exclusive and secure areas, you'll have quick access to business centers, restaurants, supermarkets, and more.

Popular amenities for Santa Clara, Panama City vacation rentals

  1. Airbnb
  2. Panama
  3. San Miguelito
  4. Santa Clara