Vacation rentals in Santa Clara, Panama City

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Top-rated vacation rentals in Santa Clara, Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.

Apartment in Panamá

4.97 out of 5 average rating, 112 reviews

The Spot Panama - Comfy, great view & much more

Ideally located in Panama City Panama 🇵🇦 we're just 15-20 minutes from Tocumen Airport 🛩 . Approximately 10 minutes from Albrook Mall, SoHo Mall, Alta Plaza, Multiplaza and much more! Enjoy easy access to supermarkets and restaurants!. Experience peace of mind with 24/7 security and outstanding facilities: pool, gym, and free parking! More than a stay, it's a chance to shop, unwind, and soak in Panama City views. Don't hesitate- Book instantly or contact us if you have any questions.

Top guest favorite

A comfortable sleeping area is presented with a spacious bed covered in a soft, patterned blanket. Lively artwork featuring tulips adorns the wall above, while bedside tables with lamps provide gentle illumination. Dark curtains frame the window, and air conditioning is installed overhead.

Loft in Panama

4.94 out of 5 average rating, 49 reviews

Modern apartment 20 minutes from the airport

Comfortable and cozy apartment on Av. la Pulida, 8 minutes from the Cincuentenario metro station. For business travelers and couples, this apartment features a bedroom with a full bed, a TV in the room, a full bathroom with hot water, a fully equipped kitchen, a living-dining room, a Smart TV, air conditioning, a laundry room, and a closet. It's just 8 minutes from the metro station and offers easy access to any point in the city. Centrally located, yet quiet. Enjoy a perfect stay!

Guest favorite

A panoramic view of the Panama City skyline is displayed, showcasing a lively urban landscape at dusk. The dark water reflects city lights, while notable icons for air conditioning, kitchen amenities, and WiFi are presented prominently, representing essential features of the accommodation.

Apartment in Panamá

4.92 out of 5 average rating, 25 reviews

Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá

✔️ SuperAnfitrión Verificado ¡Tu estadía estará en las mejores manos! Apartamento en Panamá, Panamá 📍Excelente ubicación 🏡 Espacio limpio, cómodo y seguro. 💬 Estoy disponible para ayudarte durante toda tu estancia. 🔑 ¡Reserva hoy y siéntete como en casa en Panamá! 👨‍👧‍👧 Ideal para todo tipo de turista El apartamento ofrece: 🌐 Wifi 📺 TV 🍳 Cocina 💻Zona de trabajo 🌬️Aire acondicionado 🚗Estacionamiento 🌸Lavadora 🧖‍♂️🧖‍♀️ducha con agua caliente

Top guest favorite

The kitchen area features a black dining table with four chairs, complementing a modern microwave and refrigerator. Warm decorative elements, including wall art and a candle, add character to the space, which is equipped with essential appliances and a clean countertop.

Home in Panamá

4.93 out of 5 average rating, 379 reviews

Estudio Privado a 10 Min del Aeropuerto !

Apartamento Entero a 10 MINUTOS del Aeropuerto! El apartamento está completamente amueblado incluyendo electrodomésticos y artículos de cocina , productos de aseo , sala comedor ,mesa de trabajo y demás. A sólo minutos caminando de la Estacion de METRO SAN ANTONIO, restaurantes, centros comerciales,lavanderias,supermercados y farmacias. Ofrecemos Tours a San Blas para que aproveches al maximo tu viaje. Nuestra casa es Tu casa en Panamá 🇵🇦

Top guest favorite

A spacious living area is highlighted by large windows that offer views of urban high-rises and the distant ocean. A soft, rounded sectional sofa and a plush armchair provide comfort, while a dark area rug anchors the space beneath a sleek coffee table.

Apartment in Costa del Este

5 out of 5 average rating, 19 reviews

Elegante Apt en Costa del Este. Amenidades Premium

Disfruta de una estancia de lujo en nuestro apartamento de diseño moderno ubicado en la exclusiva zona de Costa del Este. Cuenta con una habitación con baño privado, sala acogedora y cocina totalmente equipada. Las instalaciones del edificio incluyen gimnasio de última generación, piscina y espacio de coworking ideal para trabajo remoto. Perfecto para estancias prolongadas, combinando confort y conveniencia en el corazón de Panamá.

Top guest favorite

The kitchen features modern cabinetry and a granite countertop, equipped with stainless steel appliances. A dining table with stylish chairs is set elegantly with plates and glasses. Fresh flowers are placed in a vase, adding a touch of color to the dining area.

Apartment in Costa del Este

5 out of 5 average rating, 14 reviews

Luxury Apartment in Panama | 2BR + Views + Pool

Live a Luxury Experience in the Heart of Panama City 🏙️✨ Welcome to your home away from home: a modern and elegant apartment designed to offer you the highest level of comfort, style, and functionality. Perfect for tourists, business travelers, or remote workers, every space has been thoughtfully designed to ensure an unforgettable stay. We look forward to welcoming you and offering you a luxurious and comfortable experience.

Guest favorite

Apartment in Panamá

4.98 out of 5 average rating, 122 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Guest favorite

A modern living room is depicted, featuring a wall-mounted television above a black media console. Two light-colored armchairs are positioned beside a round coffee table, which is adorned with decorative items. A large window allows natural light and offers views of the surrounding area.

Apartment in Costa del Este

5 out of 5 average rating, 6 reviews

1bd/2Bthrm Costa del este-Panama

¿Qué esperas para conocer y disfrutar de Panamá? Alójate en nuestro apartamento moderno, amoblado y tranquilo en Costa del Este, donde podrás disfrutar de una vista espectacular, Wi-Fi rápido, cocina totalmente equipada, acceso a la piscina en el último piso con vista a la ciudad y un increíble atardecer, gimnasio y más. Rodeado de cafés, parques y todo lo que necesitas para tener la mejor experiencia en la ciudad.

Guest favorite

The living area features a light blue accent wall and a cozy gray sectional sofa accompanied by a round ottoman. A large window with striped awnings allows natural light to fill the space. Wall art and a small shelf with a clock add functional decor.

Apartment in Distrito de Panamá

4.79 out of 5 average rating, 14 reviews

Hippodrome Suites

Hippodrome Suites is located in a safe gated community in the suburbs of Panama City, just a short drive 🚘 from the Tocumen International Airport (✈️PTY), Santa Maria and Costa del Este Budiness District. City views, 24-hours security and covered parking. It is ideal for resting and working, business trips or layover nights. This condo offers a perfect mix of comfort, convenience, and tranquility.

Guest favorite

An air conditioning unit is mounted on the wall above a wooden desk. A small lamp provides soft lighting beside a potted plant. A television is positioned on the desk, with a coffee maker and utensils visible in the foreground. The entrance can be seen to the left.

Guesthouse in Panama City

4.89 out of 5 average rating, 225 reviews

#1 Studio personal 9 km Aeropuerto Internacional

Mini room independiente, Cuenta con A/C , con su baño pequeño. Ubicado cerca del Aeropuerto Internacional de Tocumen, de 10 a 13 minutos en auto. El Studio está Cerca de 2 Centros Comerciales, Metromall y Los Pueblos. La zona residencial es segura al caminar, calles organizadas y limpias. Tenemos la estación del Metro de Cerro Viento afuera en Metromall. Espacio para preparar alimentos ligeros.

Guest favorite

A modern living space features a gray sectional sofa adorned with decorative pillows. A compact table and a television are situated nearby. Large glass doors provide natural light, leading to a small outdoor area, while patterned tile flooring adds visual interest.

Apartment in San Miguelito

4.89 out of 5 average rating, 9 reviews

Apto con balcón y buena ubicación en Cerro Viento

Bienvenido a tu hogar en Cerro Viento Disfruta de este moderno apartamento de 2 habitaciones, ideal para familias o viajeros de negocios. Ubicación perfecta: a 5 minutos de Metromall, del Corredor Sur y del Metro de Panamá. * Comodidades: cocina equipada, aire acondicionado, WiFi. Ideal para estancias largas y cortas: tranquilo, limpio y con todos los servicios cerca. Reserva con confianza.

Guest favorite

A modern living area features a sleek white entertainment center, accompanied by framed black-and-white photographs on the wall. A large window provides ample natural light, highlighting the glass coffee table with candles. A minimalist armchair and decorative plant add to the sophisticated ambiance.

Condo in Panamá

4.95 out of 5 average rating, 66 reviews

Cantabria Apto boutique +WI-FI+AC

Relájate en este espacio tan tranquilo y elegante. Ideal para viajes de negocios, familias, grupos de amigos o pequeños escalas PH CANTABRIA V se encuentra a 10 minutos del Aeropuerto de Tocumen, a 5 minutos caminando de la Estación del metro. Disfruta de una cocina totalmente equipada y mantente conectado con WIFI de alta velocidad.