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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 29 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Ponderosa Valley Estates
5 out of 5 average rating, 125 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Guest favorite
A cozy living area is highlighted by a sofa, decorated with a vibrant green cushion. A small table holds decorative items, and large glass doors open to a private pool area, framed by greenery and natural light.
Apartment in San Luis
4.96 out of 5 average rating, 129 reviews

Heated Pool, 2 Queen beds private apartment! Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in La Mesa Hermosa
4.98 out of 5 average rating, 212 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
Tiny home in Yuma
4.86 out of 5 average rating, 145 reviews

Santa Fe 4 Tiny Studio

Welcome to Casa Santa Fe #4! "This boutique hotel-themed house" offers everything from single to double rooms. Santa Fe #4 is a cosy one-room studio that's fully equipped for a wonderful stay. Our fantastic communal pool area is all set for enjoyment! Just a quick note, if you fancy a dip in the jacuzzi, it does come with an extra fee of $40 USD. We've tailored everything here to provide you with a serene and peaceful stay. We're so excited for your visit!

Guest favorite
Home in Residencias
4.97 out of 5 average rating, 103 reviews

Casa Victoria | Central, Comfortable, Balcony and Garage

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Guest favorite
A close-up of a cow and a donkey is captured in a green pasture. The cow is prominently featured, with its gentle eyes and snug halter. The donkey stands nearby, also wearing a harness, contributing to the serene farm atmosphere.
Farm stay in Yuma
4.78 out of 5 average rating, 103 reviews

Adorable 1 bedroom 1 living room farm guest home

Visit this quiet county guest house and try your hand at farm living. Spend time with the cows, chickens, goats, and more. Reserve time in the pool or at the BBQ. Just minutes away from the Peanut Patch Store (Open Seasonally). 18 minutes away from the Hospital, perfect for traveling nurses or anyone visiting Yuma Long term. Take it easy at this unique and tranquil getaway. The guest house includes a refrigerator and kitchenette.

Top guest favorite
The bedroom features a spacious bed adorned with yellow and white bedding. Wooden cabinets flank the bed, each holding a lamp. A round wooden table is positioned next to a chair, offering a cozy workspace. Natural light enters through the window, decorated with light curtains.
Apartment in Yuma
4.97 out of 5 average rating, 124 reviews

Peaceful Yuma Stay

Welcome to your peaceful stay at Yuma 1 bed Apt. A charming apartment to fit comfortably up to 4 people. Perfect for short or long stays. Enjoy lazy afternoons in the shared pool and backyard. Located in a quiet, peaceful and safe neighborhood. Pool is not heated but is available all year. This apartment is adjacent to another airbnb property. Complete apartment is 100% private.Access to shared pool and backyard

Superhost
The modern house is presented with a sleek façade featuring contrasting dark and light colors. A driveway leads to a garage with horizontal design elements. Flanking the entrance are palm trees, and soft landscaping enhances the welcoming appearance of the home.
Home in San Luis
4.92 out of 5 average rating, 106 reviews

Contemporary 3 Bedroom Home + Pool

Kick back and relax in this calm and stylish space. This brand new-modern house is amazing !! with a play pool in the backyard and a grill to delight a tasty roast !! furniture super comfortable and a 85" TV in the living room to see your favorite movies ! located near Yuma and the border . Close to an urgent care , gas station , gym, supermarket and restaurants .

Top guest favorite
A single-story house features a light-colored exterior and a dark wooden front door. Two windows are positioned symmetrically on either side of the entrance. A stone pathway leads up to the door, surrounded by gravel and bordered by a wooden fence.
Guesthouse in San Luis
5 out of 5 average rating, 39 reviews

Warm & Modern | Casa Luna w/ Patio & Kitchen

Welcome to Casa Luna! Casa Luna is your cozy and peaceful retreat ✨ A spacious bedroom, private bathroom, fully equipped kitchen, and comfy living room all in one open, inviting space ☕️🛏️ Whether you’re here to relax or explore, you’ll have everything you need for a comfortable and memorable stay. We can’t wait to welcome you! ❤️🏡

Guest favorite
A cozy living area showcases a comfortable seating arrangement with a gray sectional and a wooden coffee table. A television is mounted on the wall, while a dining space is highlighted with a glass-top table surrounded by six chairs. Soft lighting and neutral tones create a welcoming environment.
Home in Yuma
4.92 out of 5 average rating, 184 reviews

My Saguaro Casita/private pool

Enjoy your stay at "My Saguaro Casita" Has a beautiful pool, new air conditioning unit, a very comfortable home centrally located in Yuma, near the free way and shopping centers. It offers you Outside and Inside options for entertainment with family and friends. Come and enjoy our home away from home.

Superhost
Guesthouse in Somerton
4.78 out of 5 average rating, 301 reviews

Full Studio In a Ranch

Enjoy your stay in a quiet and peaceful Studio in the Counties/outskirts of Yuma and Somerton . You will see my Rottweiler Dog in the backyard as well listen to the roosters sing in the morning. You can walk around the block peacefully. Enjoy your fully fenced private yard area

Popular amenities for San Luis vacation rentals

When is the best time to visit San Luis?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in San Luis?

    San Luis has more than 120 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in San Luis?

    Experience the best of San Luis with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis?

    Four-legged friends are welcome in San Luis. Choose from more than 70 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in San Luis?

    Yes! Work meets play with ease at over 90 vacation rentals in San Luis featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there San Luis house rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 house rentals with pools in San Luis, available on Airbnb. Make a splash and soak up the sun in style!

  • Where should I stay in San Luis?

    Make yourself at home in San Luis by choosing from our most frequently booked neighborhoods. We have over 190 vacation rentals in Comercial, over 190 vacation rentals in Frontera Estates, and over 190 vacation rentals in Parque Industrial.

  • Do house rentals in San Luis have air conditioning?

    Absolutely! We offer over 100 house rentals with air conditioning in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in San Luis have a kitchen?

    Absolutely! We offer over 30 apartment rentals with a kitchen in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in San Luis have wifi?

    Absolutely! We offer over 40 apartment rentals with wifi in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have free parking?

    Absolutely! We offer over 100 house rentals with free parking in San Luis. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in San Luis

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis

  • Nightly prices starting at

    San Luis vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 5,110 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 70 rentals that welcome pets

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

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