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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 29 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Ponderosa Valley Estates
5 out of 5 average rating, 125 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Guest favorite
A cozy living area is highlighted by a sofa, decorated with a vibrant green cushion. A small table holds decorative items, and large glass doors open to a private pool area, framed by greenery and natural light.
Apartment in San Luis
4.96 out of 5 average rating, 129 reviews

Heated Pool, 2 Queen beds private apartment! Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Superhost
Place to stay in Yuma
4.86 out of 5 average rating, 164 reviews

Adobe Encanto “house”

Beautiful and Unique Spanish-Style Home Since 1925, this stunning Spanish-style house has been part of Yuma, AZ’s rich history. Recently renovated, it features a vibrant, colorful design and a lush garden perfect for relaxing and spending time with your family. The home sits on a large lot, and the backyard is divided by a fence that separates it from a charming tiny house—also an Airbnb. Both homes are completely independent and do not share any spaces.

Top guest favorite
A spacious bed is placed against a soft blue wall, featuring a neutral quilt and decorative striped pillow. Natural light is captured through a window with light curtains, enhancing the calming ambiance of the room, complemented by a macramé wall hanging.
Apartment in San Luis
5 out of 5 average rating, 28 reviews

Private Studio | Quiet & Comfy | Separate Entry

This charming 1-bed / 1-bath Studio offers a cozy and inviting space perfect for anyone seeking comfort and convenience. Ideally located near the border, convenience stores. The studio features a well-equipped kitchenette, allowing for simple meal preparation, and a bright, open layout that maximizes space. With its central location, you're just moments away from everything you need, 5 min from the border with Mexico and 25 min from Yuma, Az.

Guest favorite
Home in Residencias
4.97 out of 5 average rating, 103 reviews

Casa Victoria | Central, Comfortable, Balcony and Garage

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Guest favorite
A bright living area features a comfortable sectional sofa and a patterned area rug. Natural light filters through sheer curtains, illuminating the space. A stylish cabinet houses a TV, while potted plants add a touch of greenery to the inviting atmosphere.
Home in Yuma
4.94 out of 5 average rating, 398 reviews

LUXURY Living!

You will enjoy your stay at this fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet cul-de-sac. Relax on the large covered patio, next to the pool, or by fire pit. Great location in the center of town near the hospital, golf courses, shopping, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.

Guest favorite
Guesthouse in La Mesa Hermosa
4.89 out of 5 average rating, 113 reviews

Comfortable Art Deco Studio in the Heart of Yuma

Enjoy your stay in Yuma in this artistic beautiful studio. Fitting up to 4 guests in a comfortable queen size bed and an air mattress. Full bathroom, spacious kitchen with all the utensils. We are 5 min to Onvida Hospital, 10 min away from Yuma Palms mall and airport, within walking distance to restaurants, coffee shops and supermarkets. Washer and dryer available for guests.

Guest favorite
Home in Palo Verde
4.81 out of 5 average rating, 176 reviews

Yuma Cozy Casita

Enjoy our cozy home. Less than a mile away from the Yuma airport. We welcome you to come to enjoy The beautiful weather yuma has to offer in the winter. You will also have a dedicated workspace with a desk. Close to all your shopping needs. Algodones is about 25 minutes, and San Luis Mexico is approx. 45 minutes. Please note that the POOL IS NOT GATED, NOR HEATED.

Superhost
The modern house is presented with a sleek façade featuring contrasting dark and light colors. A driveway leads to a garage with horizontal design elements. Flanking the entrance are palm trees, and soft landscaping enhances the welcoming appearance of the home.
Home in San Luis
4.92 out of 5 average rating, 106 reviews

Contemporary 3 Bedroom Home + Pool

Kick back and relax in this calm and stylish space. This brand new-modern house is amazing !! with a play pool in the backyard and a grill to delight a tasty roast !! furniture super comfortable and a 85" TV in the living room to see your favorite movies ! located near Yuma and the border . Close to an urgent care , gas station , gym, supermarket and restaurants .

Guest favorite
A cozy sleeping area features a spacious bed with soft gray bedding and multiple plush pillows. A decorative wall map is displayed above the headboard, and a bedside lamp provides soft lighting. A small plant and a framed picture add subtle touches to the room.
Apartment in San Luis Río Colorado
4.98 out of 5 average rating, 88 reviews

Comfortable SLRC Apartment

Keep it simple at this peaceful and centrally-located place. Located in the geographic center of San Luis Rio Colorado, very close to the main shops, schools, and workplaces. 10 minutes from the international border crossing. This apartment is attached to a single-family house but has a separate entrance, private bathroom and a parking space in a closed garage.

Top guest favorite
A single-story house features a light-colored exterior and a dark wooden front door. Two windows are positioned symmetrically on either side of the entrance. A stone pathway leads up to the door, surrounded by gravel and bordered by a wooden fence.
Guesthouse in San Luis
5 out of 5 average rating, 39 reviews

Warm & Modern | Casa Luna w/ Patio & Kitchen

Welcome to Casa Luna! Casa Luna is your cozy and peaceful retreat ✨ A spacious bedroom, private bathroom, fully equipped kitchen, and comfy living room all in one open, inviting space ☕️🛏️ Whether you’re here to relax or explore, you’ll have everything you need for a comfortable and memorable stay. We can’t wait to welcome you! ❤️🏡

Popular amenities for San Luis vacation rentals

When is the best time to visit San Luis?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in San Luis?

    San Luis has more than 120 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in San Luis?

    Experience the best of San Luis with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis?

    Four-legged friends are welcome in San Luis. Choose from more than 70 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in San Luis?

    Yes! Work meets play with ease at over 90 vacation rentals in San Luis featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there San Luis house rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 house rentals with pools in San Luis, available on Airbnb. Make a splash and soak up the sun in style!

  • Where should I stay in San Luis?

    Make yourself at home in San Luis by choosing from our most frequently booked neighborhoods. We have over 190 vacation rentals in Comercial, over 190 vacation rentals in Frontera Estates, and over 190 vacation rentals in Parque Industrial.

  • Do house rentals in San Luis have air conditioning?

    Absolutely! We offer over 100 house rentals with air conditioning in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in San Luis have a kitchen?

    Absolutely! We offer over 30 apartment rentals with a kitchen in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in San Luis have wifi?

    Absolutely! We offer over 40 apartment rentals with wifi in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have free parking?

    Absolutely! We offer over 100 house rentals with free parking in San Luis. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in San Luis

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis

  • Nightly prices starting at

    San Luis vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 5,110 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 70 rentals that welcome pets

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

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