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House vacation rentals in San Luis

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Top-rated house rentals in San Luis

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Yuma
5 out of 5 average rating, 148 reviews

Desert Escape Heated Pool/2king beds/ Toy parking

Year-Round Comfort and Relaxation in Yuma Escape the summer heat or bask in the warm winter sun in this private, tranquil retreat. This spacious home offers everything you need to unwind and enjoy your time in Yuma. 2 king beds & 2.5 baths there is plenty of space. Conveniently located close to I-8 shopping, dining, and fuel. Whether you are looking to relax in the sun, cool off in the pool, or enjoy time with family and friends, this is the perfect place to make the most of your stay in Yuma.

Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 29 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
The exterior of the home features a spacious front yard with artificial turf and a curved pathway leading to the entrance. A two-car garage with dark doors is visible, complemented by a distinctive tiled roof and large arched windows.
Home in Mesa del Sol
4.98 out of 5 average rating, 107 reviews

La Casa De Tortuga

This pool (fee to heat) home boasts an incredible 2400 sqFt. 4 bedroom , 3 bathrooms. This stunning master bath has a large walk-in glass shower with 2 shower heads. Also featured is a beautiful soaking tub, and a delightful view of this crisp-modern yet romantic bath right from the adjustable kind sized bed, with *Ah Hem* MASSAGE! If you need a break from the day, you'll definitely find total comfort and relaxation in this Master suite! Love the outdoors? Telegraph Pass is a 10 minute drive.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Ponderosa Valley Estates
5 out of 5 average rating, 125 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Superhost
A single-story home is presented with a tiled roof and stone accents. Lush greenery frames the entrance, with gravel landscaping surrounding the property. A driveway leads to a garage, and a rock feature adds a natural element to the front yard.
Home in Yuma
4.83 out of 5 average rating, 110 reviews

Large beautiful 3 bedroom pool home

Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in La Mesa Hermosa
4.98 out of 5 average rating, 212 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
A cozy living area features two brown sofas with accent pillows, positioned around a central coffee table. Natural light enters through large sliding doors, which are framed by floor-to-ceiling curtains. A green plant adds a touch of nature to the space.
Home in Falls Ranch
4.93 out of 5 average rating, 116 reviews

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA

Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Guest favorite
A bright living area is highlighted by a white sectional sofa and a plush area rug. Natural light enters through windows, illuminating the space. Two hanging pendant lights provide soft overhead lighting. A kitchen island is visible in the background, along with bar stools and decorative wall art.
Home in Yuma
4.94 out of 5 average rating, 120 reviews

Yuma Boho/Airy 3 bedroom home with free parking

Bring the whole family to this great place with lots of room for fun. This townhome is located in a new neighborhood in Yuma. This is a new built spacious home that was decorated to make it your little home away from home . Conveniently located near Walmart and shops. We are located close to Yuma palms mall where there is lots of places to eat, shop and entertainment. The house is equipped with all you need to make sure you have the best stay away from home.

Guest favorite
Home in Residencias
4.97 out of 5 average rating, 103 reviews

Casa Victoria | Central, Comfortable, Balcony and Garage

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Top guest favorite
A modern living area features a charcoal gray sectional sofa adorned with holiday-themed pillows. A wooden coffee table sits in front, displaying decorative items. In the background, a dining area with a small table and chairs is visible, along with light-colored curtains framing the windows.
Home in Yuma
4.96 out of 5 average rating, 101 reviews

Bee House

ATTENTION: Border Patrol, Military, First Responders, and Traveling Nurses! Great place for fishermen/boaters and hunters with room for boats and RVs. ‘Bee’ our guest at this sweet, modern one bedroom home. Our home features a large smart tv, Keurig, coffee pot, blender, toaster oven/air fryer, etc. Couch pulls out to be used as a sleeper. Futon available and located in the bedroom. The house is professionally cleaned.

Guest favorite
Home in Palo Verde
4.81 out of 5 average rating, 176 reviews

Yuma Cozy Casita

Enjoy our cozy home. Less than a mile away from the Yuma airport. We welcome you to come to enjoy The beautiful weather yuma has to offer in the winter. You will also have a dedicated workspace with a desk. Close to all your shopping needs. Algodones is about 25 minutes, and San Luis Mexico is approx. 45 minutes. Please note that the POOL IS NOT GATED, NOR HEATED.

Superhost
The modern house is presented with a sleek façade featuring contrasting dark and light colors. A driveway leads to a garage with horizontal design elements. Flanking the entrance are palm trees, and soft landscaping enhances the welcoming appearance of the home.
Home in San Luis
4.92 out of 5 average rating, 106 reviews

Contemporary 3 Bedroom Home + Pool

Kick back and relax in this calm and stylish space. This brand new-modern house is amazing !! with a play pool in the backyard and a grill to delight a tasty roast !! furniture super comfortable and a 85" TV in the living room to see your favorite movies ! located near Yuma and the border . Close to an urgent care , gas station , gym, supermarket and restaurants .

Popular amenities for San Luis house rentals

When is the best time to visit San Luis?

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Avg. priceﺩ.ﺇ338ﺩ.ﺇ382ﺩ.ﺇ353ﺩ.ﺇ364ﺩ.ﺇ386ﺩ.ﺇ382ﺩ.ﺇ371ﺩ.ﺇ375ﺩ.ﺇ367ﺩ.ﺇ334ﺩ.ﺇ367ﺩ.ﺇ378
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Quick stats about house rentals in San Luis

  • Total vacation rentals

    Explore 100 vacation rentals in San Luis

  • Nightly prices starting at

    San Luis vacation rentals start at ﺩ.ﺇ73 per night before taxes and fees

  • Verified guest reviews

    Over 2,550 verified reviews to help you choose

  • Family-friendly vacation rentals

    90 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    50 properties have a dedicated workspace

  • Wi-Fi availability

    100 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

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