Vacation rentals in Carlisle

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Carlisle

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Guest favorite
The kitchen features classic wooden cabinetry and retro-style appliances, including a pale cream refrigerator. A patterned backsplash complements the checkered floor, while shelves display colorful dinnerware. Natural light fills the space, enhancing the inviting atmosphere for cooking and gathering.
Home in Ankeny
4.97 out of 5 average rating, 202 reviews

Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar

Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5) & hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants. Up to 2 dogs allowed for an additional fee. ***Events/photo shoots are allowed with written permission only and will be an added fee. No events larger than 25 total.***

Guest favorite
A cozy living room features a reclining loveseat and couch, complemented by a wooden coffee table with a decorative basket. A ceiling fan hangs above, while woven wall decor adds warmth to the space. Light enters through windows covered with blinds, creating a welcoming atmosphere.
Apartment in Des Moines
4.85 out of 5 average rating, 110 reviews

Hillside Haven | Private Entry | Near Downtown

Escape to this charming apartment in the Indianola Hills neighborhood- minutes from downtown Des Moines, the airport, & some of the city’s best dining & entertainment. Pull up the driveway and enter through your private entrance. Inside, enjoy a warm & welcoming space designed for comfort: ✨Queen-size bed 📚Cozy reading nook 📺 55” smart TV 🛁Full-size tub Whether you’re here for business, a romantic escape, or just passing through, this little hideaway has everything you need to feel at home.

Top guest favorite
Cabin in Prole
4.98 out of 5 average rating, 121 reviews

Tranquil Cabin Retreat Near Des Moines

Welcome to Timberlandia! Just south of the Metro, at the border of Madison & Warren counties in the Middle River Valley, the cabin is on 2 acres of shaded lawns with plenty of exploring options on 18 acres of wooded paths & walking trails. Timberlandia is a secluded tranquil getaway, but only 15 minutes from the Airport, 20 minutes from West Des Moines Jordan Creek, and 25 minutes from downtown. Our cabin is great for romantic getaways, family gatherings, festivals, retreats & wedding stays.

Top guest favorite
A spacious living area features large windows, offering expansive views of the skyline. Modern furnishings include a cozy couch, two accent chairs, and a coffee table. A sleek electric fireplace is positioned beneath a wall-mounted TV, enhancing the contemporary design of the space.
Townhouse in Des Moines
4.94 out of 5 average rating, 149 reviews

This is the best Des Moines has to offer!

Welcome to a beautiful 3 story townhome in the heart of Des Moines. If an upscale modern home with an incredible view is your thing, you will be in heaven. Inside you’ll find a clean, bright and well decorated home with all the amenities you'll need to kick back, relax and enjoy your stay. Minutes from shopping, dining and nightlife. The bike trail is across the street where you can ride to Gray’s Lake or stroll to downtown DSM and enjoy the Farmer's Market, Civic Center and Principal Park.

Guest favorite
A spacious farmhouse is situated on a grassy expanse, framed by a serene sunset. The two-story structure features large windows, providing ample natural light. The building's exterior is painted in a calm gray with white accents, complemented by a welcoming front entrance.
Farm stay in Carlisle
4.79 out of 5 average rating, 107 reviews

Country Charm Homestead

Our farmhouse homestead retreat offers the quiet and private country space, while being conveniently located near the airport and downtown Des Moines and the Iowa State Fairgrounds. This 5400 sq ft home offers 5 bedrooms and 4 bathrooms with a 500 sq ft Master Suite that has it’s own private bathroom with a whirlpool tub. The property sits on over 2 acres with a comfortable walkout back porch with a fire pit. It is perfect for extended work trips, short term rental opportunities and groups.

Guest favorite
An open-concept living area features a cozy dining table with four chairs, complemented by a floral-patterned refrigerator. Two comfortable armchairs are positioned near a light-colored rug, while natural light illuminates the wood-tone cabinets and kitchen space in the background.
Home in Des Moines
4.85 out of 5 average rating, 195 reviews

Effortless Landing near Airport & Downtown

Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in couch, local coffee, & all the amenities like fiber wifi, TV, linens, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

Top guest favorite
Apartment in Des Moines
4.95 out of 5 average rating, 989 reviews

Unique "Little Italy" Apartment

Drive into the attached garage and go upstairs where you will find your very private entrance to a quiet, peaceful, and restful living. Located 1 mile from the downtown area on a street loaded with large Oak and Walnut trees. A huge back yard in which to stroll or barbecue. It is the top half of my house complete with it's own kitchen, bathroom, and bedroom. My residence is the bottom half of the house. Lots of excellent restaurants nearby. Check out the "Guide to Restaurants".

Top guest favorite
An open living area showcases comfortable seating and a decorative ottoman on a dark rug. The kitchen is visible in the background, featuring wooden cabinetry and appliances. Walls are adorned with framed art, contributing to a well-appointed and welcoming space.
Guest suite in Pleasant Hill
5.0 out of 5 average rating, 231 reviews

Windy Pines Suite

Windy Pines offers a spacious bedroom with a comfortable king sized bed and large bathroom. The kitchen and living room are great. This clean, comfortable, & uncluttered space is a home away from home! You will be surrounded by beautiful greenery, in a safe neighborhood with accessible parking. Close to interstate 80 & 35, the Iowa State Fair Grounds, and Downtown Des Moines. WP is attached to our home but with its own separate outside entrance. Please send me any questions.

Top guest favorite
A spacious living area features a modern design with a large sofa and two green accent chairs. A sleek entertainment unit with a fireplace is centered on the wall. Large windows provide natural light, enhancing the open and airy atmosphere.
Barn in Des Moines
5.0 out of 5 average rating, 169 reviews

8000sqft Barndo | Indoor Court + 2 Living Qtrs

Welcome to The Lodge on 3rd - a massive 8000 sq ft Barndominum. Nestled in the heart of Des Moines, Iowa, this stunning retreat offers the perfect blend of rustic charm and modern elegance. With 4 spacious bedrooms and a large loft, there is plenty of room for you and your guests to unwind in style. This property is next door to Luxury Living on Third. airbnb.com/h/luxurylivingonthird These combined properties are ideal for family reunions, etc. ***$200 Pet Fee***

Top guest favorite
A newly remodeled home is showcased, featuring a welcoming facade with a mix of light and dark exterior colors. A concrete driveway leads to the entrance, surrounded by a well-kept lawn and mature trees. A detached garage is visible nearby.
Home in Indianola
4.93 out of 5 average rating, 198 reviews

Charming Home in Indianola

Discover comfort in our newly remodeled 3-bedroom home in the heart of Indianola, Iowa. This charming space boasts modern amenities and stylish decor, providing a cozy retreat for your stay. Enjoy a fully equipped kitchen, spacious living areas, and a modern bathroom. Perfect for families or groups, our home offers a blend of convenience and warmth. Explore nearby attractions or simply relax in our inviting space. Your home away from home awaits in Indianola!

Top guest favorite
A sunroom features large windows allowing natural light to illuminate the space. An orange sectional sofa is complemented by a colorful throw pillow. A wooden console table with decorative items sits against the wall, while plants add a touch of greenery to the inviting atmosphere.
Home in Des Moines
4.98 out of 5 average rating, 151 reviews

White Oak Hillside Oasis

Our 3 bedroom hilltop 1950’s home with wonderful views of the capital and city of Des Moines is the perfect place for your stay. Nestled just south of downtown in a quiet historic Italian neighborhood, you are within walking distance from a world class brewery, bars, restaurants and miles of walking and biking trails surrounding Gray’s Lake. We are within a few miles of everything else that the downtown area of Des Moines has to offer!

Top guest favorite
The exterior of a galaxy bell tent is softly illuminated by string lights, highlighting its unique shape. The surrounding area features a natural landscape, with trees visible in the background, creating a serene nighttime setting.
Tent in Perry
4.95 out of 5 average rating, 251 reviews

Relaxing galaxy bell tent getaway

Come sleep under the stars in this cozy galaxy bell tent. You can enjoy a good nights sleep in the comfortable King bed and stay comfortable with an air conditioner and heater. There is also a fridge for keeping your food fresh. Soak up nature while you hike the trails around Oak Haven Acres, a 32 acre farm in rural Iowa. For your security we have a trail camera at the beginning of the driveway that won’t intrude on your privacy.

Popular amenities for Carlisle vacation rentals