Guesthouse vacation rentals in Port St. Lucie

"Serene Escape" Private Apartment Style Guesthouse

Welcome to Serene Escape ✨ Your cozy and private retreat awaits! 🛋️💛 Step inside through your own private entrance and enjoy the comfort of a queen bed, sofa bed, and your very own bathroom. A convenient kitchenette with dining area and two spacious closets make your stay feel just like home. Stay entertained with Netflix and fast WiFi, and park stress-free in your private spot. Whether you’re here to relax, work, or enjoy a mini getaway, Serene Escape offers comfort, privacy, and good vibes

Location · Decor · Condition

Large In-law suite screened in porch w/pool access

This large 1-bedroom, 1-bathroom home offers expansive living areas, dinning table and a private screened patio overlooking the pool—perfect for relaxation. Centrally located, you'll have easy access to everything, whether you're exploring local dining, shopping, or outdoor adventures. You'll share the main entrance, pool, and common areas with the friendly homeowner and their beloved rescue dog. Parking is dedicated to you, it is to the right of the main driveway (curved drive with pavers)

Family · Location · Getting around

Cozy River Retreat

Conveniently located within a short driving distance from the beach 'Cozy River Retreat,' offers an oasis in Florida that seamlessly combines retreat, comfort, adventure, relaxation, and outdoor cooking. Whether kayaking and fishing by the river, unwinding by the fire pit, or cooking outdoors on the BBQ, discover your perfect escape where tranquility meets excitement." Enjoy the gentle rustle of palms and the soothing breeze as you step into our cozy accommodation, designed with you in mind.

Location · Value · Parking

Cozy place in sunny Vero Beach!

Relax with the family in this peaceful getaway. Enjoy the entire unit with private access, featuring 1 bedroom with king bed and 1 bathroom with essentials. Sofa in living room is a queen-size sofa bed, and the fully equipped kitchen includes dishes for four. You’ll also have your own washer and dryer, plus access to the shared pool. The owners’ residence is located on the same property. The property is just 7 miles from the beach, with plenty of restaurants, shops, and attractions nearby!

Value · Location · Bathroom

Comfy and Cozy

Comfy for one and Cozy for two - efficiency apartment. 10 min. drive to public beaches and 20 min. leisurely walk to downtown Stuart -full of inviting shops, restaurants, and music. Laundry facilities available for guests who are here at least a week. One of House Beautiful Magazine's Top Ten charming USA towns: #10 - Stuart, Florida The "sailfish capital of the world" is best for those who love the perfect climate during the winter but want a less touristy destination to soak up some sun.

Value · Location · Hospitality

Coastal Retreat

Kick back and relax in this calm, stylish space. Whether you are sent to work or a vacation with family you will be glad you came! Plenty of shopping and restaurants 5 minutes away. If you are a beach lover it’s 20-30 minutes drive to any beach you chose. For families we have a play pin available and a sectional couch that a couple of kiddos could sleep on. The queen bed is adjustable for extra comfort. Laundry room is available in house. Kitchenette has all you need to eat in or delivery.

Value · Family · Cleanliness

Private Detached Guesthouse Oasis

North Hutchinson Island locale a two minute walk to private beach/Indian River Lagoon/fishing dock. Preserve, and, park surroundings, great hiking trails, and, awesome fishing spots. Guest house, with bedroom, living room, and bathroom, includes an alcove with small fridge, Keurig, toaster oven, and microwave. -Never a cleaning fee -No pre check-out chores -This is a private property -Two night weekend minimum -10% discount off nightly rate 3 nights or more (paid in cash upon arrival)

Value · Location · Comfort

Private•Stylish guesthouse•Laundry inside•King bed

Feel at home in our totally private apartment, in a quiet neighborhood with all you need for a relaxing stay. Relax in the comfort of a spacious King bed and a cozy queen sofa bed providing ample space for additional guests. Newly added washer and dryer inside the unit for a quick wash. With its own private entrance, and safe and free parking you'll enjoy the freedom to come and go as you please. Stay connected with high-speed WiFi, and smart tvs on the bedroom and the living room.

Family · Value · Wifi

Serene Guesthouse | Saltwater Pool & Private Entry

Our recently remodeled guest-room with queen bed and full bath is detached from the main house offers our guest the sweet serenity of a home away from home. The in-ground pool just feet from the sliding glass doors and private entrance on the side of the house. We are just 10 mins. away from Jensen beach and Hutchinson Island, the mall, Publix, Walmart ect.. The area is full of restaurants, to navigate to I-95 is only a 20 min. drive, West Palm is about 30-45 mins!

Value · Family · Biking

Extraordinary location, private, beach path, cozy

Location, privacy, ocean. Due to health concerns, pool seen from aerial shots not available Nov-May because owners will be in residence in the main house. Welcome to Nova Beach Cottage, the guest house on the oceanfront estate of famous sculptor, Mihai Popa, a.k.a. “Nova”. Located on the south tip of North Hutchinson Island directly next to the Fort Pierce Inlet State Park. Garden and beach path a few steps from the cottage. Screened patio from bedroom.

Value · Location · Quiet

Sunny Boho Oasis – Casita Luna

One of the most beloved homes on Airbnb, fall in LOVE with Casita Luna! * Stand alone Casita Luna is designer decorated, a perfect base to explore Treasure Coast & beaches! * Enjoy your organic coffee or get work done in the window alcove * Sink into comfortable queen bed with luxurious linens, enjoy fully stocked kitchenette & a spacious bath * Watch Prime & Netflix, play games, browse through books * Convenience for long stays * Lovely private patio

Location · Value · Indoor spaces

Cozy Island Efficiency • Walk to Beach

Welcome to our cozy efficiency on South Hutchinson Island, Florida! Our one bedroom is perfect for singles or couples, with a queen Murphy bed and private ground-level entrance. an induction cooktop, convection oven, full-size refrigerator, Smart TV, and a full bathroom. Located in a friendly neighborhood, we're close to beaches, jetties, restaurants, and historic downtown. Come stay with us and enjoy all that the Treasure Coast has to offer!

Value · Location · View