Guesthouse vacation rentals in Port St. Lucie

5 out of 5 average rating, 30 reviews

Private Coastal Studio | Walk to Food & Boating

Welcome to The Parakeet — a newly renovated historic cottage in downtown Port Salerno, a charming fishing village on Florida’s coast. Just a short stroll to waterfront restaurants, live music, marinas, and scenic views, this private retreat blends Old Florida charm with modern comfort. The Parakeet is part of a larger home, fully separated from the main house by a locked utility room with two sets of secure double doors for complete privacy. Our doors are open to all, and we’d love to host you!

The image features a designer-decorated bedroom with a comfortable bed adorned in soft linens. A decorative table holds fresh flowers, almonds, and apples, while a cozy area rug enhances the room's warmth.

5 out of 5 average rating, 73 reviews

Sunny Boho Oasis with a Pool – Casita Luna

One of the most beloved homes on Airbnb, fall in LOVE with Casita Luna! * Stand alone Casita Luna is designer decorated, a perfect base to explore Treasure Coast & beaches! * Enjoy your organic coffee or get work done in the window alcove * Bask in the the sun or swim in the pool * Sink into comfortable queen bed with luxurious linens, enjoy fully stocked kitchenette & a spacious bath * Watch Prime & Netflix, play games, browse through books * Convenience for long stays * Lovely private patio

A bright guest suite features a spacious bed with a light-colored blanket. A ceiling fan circulates air above, while a dresser and decorative wall art complete the room. Natural light filters in through a window, enhancing a calm and cozy atmosphere.

5 out of 5 average rating, 14 reviews

Hideaway Guest Suite Hot Tub, Projector, Pool Tabl

Stay in a beautiful boho themed guest suite fitted with a king size bed, bathroom and shower. This is the perfect place where you can relax and destress in your own spacious outdoor sheltered lanai, guests will have full access to the hot tub with jets, colored lights , 120 inch roll down projector, pool table, piano, lounge area, yoga zen area, mini kitchenette with basic kitchen appliances. Outdoor amenities full use of patio, grill, two reclining lounge chairs, dining table, cold shower.

Superhost

A tranquil canal scene is depicted at sunset, with a thatched-roof hut and lush palm trees framing the waterway. A lounge chair is positioned on the dock, inviting relaxation while reflecting the vibrant colors of the sky.

4.82 out of 5 average rating, 55 reviews

Cozy River Retreat

Conveniently located within a short driving distance from the beach 'Cozy River Retreat,' offers an oasis in Florida that seamlessly combines retreat, comfort, adventure, relaxation, and outdoor cooking. Whether kayaking and fishing by the river, unwinding by the fire pit, or cooking outdoors on the BBQ, discover your perfect escape where tranquility meets excitement." Enjoy the gentle rustle of palms and the soothing breeze as you step into our cozy accommodation, designed with you in mind.

An outdoor shared patio area is shown, featuring a wooden table surrounded by four wicker chairs. String lights create a warm ambiance above, and a hammock hangs nearby. The space is adorned with potted plants and a decorative star-shaped light fixture.

4.96 out of 5 average rating, 158 reviews

Comfy and Cozy

Comfy for one and Cozy for two - efficiency apartment. 10 min. drive to public beaches and 20 min. leisurely walk to downtown Stuart -full of inviting shops, restaurants, and music. Laundry facilities available for guests who are here at least a week. One of House Beautiful Magazine's Top Ten charming USA towns: #10 - Stuart, Florida The "sailfish capital of the world" is best for those who love the perfect climate during the winter but want a less touristy destination to soak up some sun.

An open-concept living area is depicted, featuring a leather sofa opposite a dining table with four chairs. The kitchen showcases modern appliances, including a stainless steel refrigerator. A washer and dryer are visible within cabinetry. Light-colored walls and wood flooring enhance the spacious feel.

4.94 out of 5 average rating, 100 reviews

Private apt. for 4, king bed, laundry inside.

Feel at home in our totally private apartment, in a quiet neighborhood with all you need for a relaxing stay. Relax in the comfort of a spacious King bed and a cozy queen sofa bed providing ample space for additional guests. Newly added washer and dryer inside the unit for a quick wash. With its own private entrance, and safe and free parking you'll enjoy the freedom to come and go as you please. Stay connected with free high-speed WiFi, and smart tvs on the bedroom and the living room.

Guesthouse in Hutchinson Island

A scenic view of the beach and water features a wide wooden boardwalk leading to the Atlantic Ocean. Lush greenery accompanies the path, with sandy areas visible in the foreground. Another section showcases a fishing dock extending over calm waters, with blue skies framed by clouds.

4.9 out of 5 average rating, 187 reviews

Private Detached Guesthouse Oasis

North Hutchinson Island locale a two minute walk to private beach/Indian River Lagoon/fishing dock. Preserve, and, park surroundings, great hiking trails, and, awesome fishing spots. Guest house, with bedroom, living room, and bathroom, includes an alcove with small fridge, Keurig, toaster oven, and microwave. -Never a cleaning fee -No pre check-out chores -This is a private property -Two night weekend minimum -10% discount off nightly rate 3 nights or more (paid in cash upon arrival)

A bright, open backyard features a circular pool with clear blue water, surrounded by a concrete deck. Two lounge chairs sit next to the pool, and an umbrella provides shade. The lush green lawn complements the bright sky with scattered clouds.

4.83 out of 5 average rating, 206 reviews

Serene Guesthouse | Saltwater Pool & Private Entry

Our recently remodeled guest-room with queen bed and full bath is detached from the main house offers our guest the sweet serenity of a home away from home. The in-ground pool just feet from the sliding glass doors and private entrance on the side of the house. We are just 10 mins. away from Jensen beach and Hutchinson Island, the mall, Publix, Walmart ect.. The area is full of restaurants, to navigate to I-95 is only a 20 min. drive, West Palm is about 30-45 mins!

An aerial view captures the spacious grounds of Nova Beach Cottage, surrounded by lush greenery and palm trees. The property is located steps from the beach, with a clear view of the ocean in the background. The layout of the buildings and pathways is evident.

4.98 out of 5 average rating, 209 reviews

Extraordinary location, private, beach path, cozy

Location, privacy, ocean. Due to health concerns, pool seen from aerial shots not available Nov-May because owners will be in residence in the main house. Welcome to Nova Beach Cottage, the guest house on the oceanfront estate of famous sculptor, Mihai Popa, a.k.a. “Nova”. Located on the south tip of North Hutchinson Island directly next to the Fort Pierce Inlet State Park. Garden and beach path a few steps from the cottage. Screened patio from bedroom.

Guesthouse in Hutchinson Island

A lush garden area features green grass, surrounded by tropical foliage and flowers. A covered patio offers a cozy seating space with soft lighting, creating an inviting atmosphere in the evening. Lanterns add a touch of warmth to the serene outdoor setting.

4.96 out of 5 average rating, 238 reviews

Cottage Efficiency on South Hutchinson Island

Welcome to our cozy efficiency on South Hutchinson Island, Florida! Our one bedroom is perfect for singles or couples, with a queen Murphy bed and private ground-level entrance. an induction cooktop, convection oven, full-size refrigerator, Smart TV, and a full bathroom. Located in a friendly neighborhood, we're close to beaches, jetties, restaurants, and historic downtown. Come stay with us and enjoy all that the Treasure Coast has to offer!

The exterior of a well-maintained home is displayed, featuring a neatly landscaped lawn with lush green grass and decorative plants. A paved driveway leads to a dark garage door. The white facade is accented by a gray metal roof and surrounded by a tidy white fence.

4.9 out of 5 average rating, 378 reviews

Port St Lucie - Peaceful home away from home.

Defined as a dwelling attached to my private home with its own private entrance, containing all the essentials of a home. Lovely, safe, quiet, family neighborhood, decorated with blackout drapes. Host only 1 person or 1 couple max at a time. Freshly renovated with private patio, independent with full kitchen. Mini fridge, coffee maker, microwave, Iron, hair dryer available. 42” LCD tv/premium channels, WiFi, streaming.

4.8 out of 5 average rating, 160 reviews

The exterior of a quaint cottage is captured, featuring light-colored siding and blue accents. A pathway made of stone leads to the entrance, bordered by lush green grass and small shrubs. A blue canopy is positioned over part of the entrance area.

Guesthouse in Hobe Sound

Sandee's Cottage

Cute little cottage in a quiet small beach town neighborhood. One and a half miles to beautiful Hobe Sound Beach, an easy walk or bike ride.! Plenty of little shops and grocery stores within a mile of the cottage. If you like fishing bring your poles, lots of good spot Animals under 40lbs. are welcome; we do have a nice fenced in yard.! No cats! Highly allergic!!! A 25.00 fee 1 time will be charged for all pets

Popular amenities for Port St. Lucie guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

New place to stay

Organic Hideaway, Jungle Suite

Guesthouse in Palm City

New place to stay

Estelle's Place

A light-filled mini-living room features a white couch paired with a wooden coffee table. A small dining table with two chairs occupies the corner by a window. Subtle wall art adds character to the serene space, which is adorned with tiled flooring.

Your own vacation mini-house

A spacious outdoor dining area features a large table surrounded by comfortable chairs, with a ceiling fan overhead. The screened space opens directly to the pool area, providing views of lounge chairs and greenery in the background. Natural light enhances the inviting setup.

Your King suite with YOUR pool

The image displays a charming single-story building surrounded by lush greenery. The exterior features a light-colored facade and a small porch area with four white lounge chairs. Tall palm trees provide shade, while a grassy yard offers an open and inviting outdoor space.

Guest Cottage

The exterior of the Mediterranean-style guesthouse is showcased, featuring a tiled roof and light-colored stucco walls. A wooden door with a modern light fixture is visible, alongside two garage doors. Lush greenery and a paved area enhance the inviting atmosphere of the entrance.

Casa Sol: Historic Beachy Villa

A deep blue sofa is highlighted in the living area, adorned with two white, fluffy pillows. In the background, a neatly made bed with navy blue headboard is visible alongside two bedside lamps and a blue cabinet. A large mirror reflects the room's openness.

4.43 out of 5 average rating, 7 reviews

Cozy /Tranquil Private Studio in the Beautiful PSL

4.93 out of 5 average rating, 15 reviews

Serenity Now.

Guest house rentals with a patio

A wooden boardwalk extends towards the horizon, leading through sea oats to a sunset over the ocean. Soft colors of orange and blue blend in the sky, while gentle waves meet the sandy shore in the distance.

5 out of 5 average rating, 10 reviews

Sunshine house -15 min from Beach & Downtown-

4.97 out of 5 average rating, 31 reviews

A serene view of the waterway is presented from a wooden railing. Lush trees line the banks, reflected on the calm surface of the water, while boats are anchored along the dock in the distance, creating a peaceful natural atmosphere.

Guesthouse in Palm City

New Waterfront Hideaway Studio!

A vibrant pool area is framed by two guest house structures in contrasting colors. Lounge chairs are positioned next to the inviting water. Brightly colored pool floats, including a pink flamingo, rest on the surface, while soft drapery provides shade over the seating area.

5 out of 5 average rating, 14 reviews

Casola Guest House By the Beach Historic Stuart FL

A clean and spacious room features a wooden bed with soft pillows, dressed in patterned bedding. A wall-mounted television is positioned across from the bed, while dark curtains frame the window, providing privacy. Terrazzo tile flooring adds a warm touch to the space.

4.94 out of 5 average rating, 17 reviews

Clean And Cozy! Boat Parking!

A spacious guest house interior showcases a cozy seating area with a dark sofa and a television unit. Light-colored walls enhance the brightness, while a blue bed with subtle patterns is positioned near a doorway. A kitchen area with open shelving is subtly visible in the background.

4.94 out of 5 average rating, 98 reviews

Modern Guesthouse Minutes From Beaches & DT Stuart

4.98 out of 5 average rating, 66 reviews

A modern kitchen features sleek cabinetry with a light gray finish. Stainless steel appliances, including a full-sized refrigerator and convection microwave oven, complement the spacious white countertop. A blue tile backsplash adds a subtle pop of color. Two bar stools are positioned for dining.

Guesthouse in Hobe Sound

Adorable 1 bed/bath just 1 mile to the beach.

A comfortable living area is furnished with a large sectional couch adorned with decorative pillows. A glass coffee table sits in the center, complemented by a small green plant. Natural light fills the space through a curtain-draped window, while a flat-screen TV is mounted on the wall.

4.91 out of 5 average rating, 46 reviews

Coastal Retreat

The bedroom features a spacious bed adorned with neutral-toned bedding and decorative pillows. Soft lighting is provided by two bedside lamps on white nightstands. A vibrant artwork depicting a beach scene is mounted on the wall opposite the bed, while a large window offers natural light filtered through sheer curtains.

4.98 out of 5 average rating, 41 reviews

Sunnyside apt. near downtown

Guest house rentals with a washer and dryer

4.97 out of 5 average rating, 64 reviews

The entrance features a black door adorned with a decorative sign, framed by greenery and twinkling string lights. A welcoming doormat sits on the stone pathway, leading to the inviting interior of the guest house.

Guesthouse in Palm City

Blue Mind -Waterfront Home’s Guest House w/Dockage

An open living space features a modern kitchen with gray cabinetry adjacent to a wooden dining table surrounded by four chairs. A large mural of an octopus brightens the area, while a comfortable sectional couch and a TV add to the inviting atmosphere.

4.97 out of 5 average rating, 39 reviews

The Eight Legged Sailor, Downtown Stuart, Boating

Superhost

An aerial view captures a scenic coastal area, featuring a channel with boats and lush greenery along the water's edge. Residential buildings are visible along the shoreline, with roads and marinas stretching through the landscape under a clear blue sky.

Guesthouse in Hutchinson Island

Cozy 1/1 Island Getaway walk to beach/Restaurants

Superhost

New place to stay

Welcome to Aqua Aura of Stuart

The exterior of a two-story building is showcased, surrounded by lush greenery and palm trees. A well-maintained lawn is visible, with a paved driveway leading to the entrance. Soft evening lighting highlights the architectural details, offering a serene and inviting atmosphere.

4.91 out of 5 average rating, 33 reviews

1 Bed Studio Pet & Boat OK Near Marina & Beach

The living area is equipped with two leather sofas facing a wooden coffee table, creating a cozy seating arrangement. A large wall art piece is displayed above the table, while a ceiling fan provides comfort. Natural light enters through the windows, illuminating the space.

5 out of 5 average rating, 8 reviews

Epiphany's hideaway

The living area is equipped with a flat-screen TV and a stylish black coffee table. A cozy sofa faces the television, while a bookshelf featuring decorative items stands in the corner. The bright kitchen area is visible, highlighting modern white cabinetry and appliances.

4.92 out of 5 average rating, 151 reviews

Renovated 1/1 Guest House Apartment -Pets Welcome!

A bright bedroom features a spacious bed with a striped blanket and several pillows. Light streams through plantation shutters in the windows, illuminating the room. A dresser and colorful wall art depicting beach huts are visible, enhancing the serene atmosphere of the space.