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House vacation rentals in Patagonia

Find and book unique houses on Airbnb

Top-rated house rentals in Patagonia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
The spacious ranch house is situated on a gravel driveway, surrounded by green grass and gently rolling hills. A clear blue sky with wispy clouds serves as a backdrop, highlighting the peaceful rural setting and bringing attention to the home's exterior features.
Home in Sonoita
4.94 out of 5 average rating, 102 reviews

McFitz Guest Ranch

McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

Top guest favorite
A serene landscape features rolling mountains bathed in warm light from a setting sun. The view encompasses lush greenery and a dirt path leading to a guest house nestled among the hills, highlighting a peaceful rural retreat.
Home in Patagonia
5 out of 5 average rating, 36 reviews

Serenity, Starlink and waking up with bird songs

Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

Guest favorite
A southwestern-style ranch home is nestled on expansive land, surrounded by rolling plains. The structure features a white exterior with traditional architectural elements. Majestic mountains are visible in the distance under a clear sky, enhancing the serene rural landscape.
Home in Elgin
4.93 out of 5 average rating, 165 reviews

Peaceful SW-style ranch home in wine country

Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

Top guest favorite
A dining area features a long wooden table surrounded by six dark chairs. A large chandelier shaped like a star hangs above the table, casting intricate patterns on the walls. A decorative centerpiece of fresh fruits adds a touch of color.
Home in Tubac
5 out of 5 average rating, 142 reviews

A Tubac Getaway

Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Guest favorite
A spacious living area features a light-colored sofa with colorful accent pillows and a glass coffee table. Artwork adorns the walls, while natural light filters in through a window. A dining area with chairs and a modern workspace is visible in the background.
Home in Patagonia
4.94 out of 5 average rating, 109 reviews

Cottage on Santa Rita | Sundrenched 2 bd/1 bth

Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Superhost
Home in Nogales
4.84 out of 5 average rating, 187 reviews

Beautiful downtown house 10 minutes from the consulate and CAS.

Centrally located house with private parking ideal for visa procedures, business trips or just to relax and enjoy the day in this beautiful accommodation, it is located in a very safe and quiet area. 🛒Close to supermarkets, bakery, laundries, stationery stores and more. 🍕Close to restaurants, taco stands, plazas, and shops. 🔑100% autonomous access through a key safe, no need for a personal meeting, designed to make you feel at home. INVOICES ARE ISSUED

Top guest favorite
Home in Patagonia
5 out of 5 average rating, 7 reviews

Peaceful Family Friendly + Fire Pit + Volleyball

Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Top guest favorite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 285 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Top guest favorite
A scenic view showcases expansive green grass and a well-maintained golf course. Majestic mountains are visible in the background, framed by trees. Light shadows create a serene landscape under clear skies.
Home in Green Valley
4.96 out of 5 average rating, 148 reviews

Green Valley Golfers Haven

This home is perfect for a visit to Green Valley, Az. It sits on The Haven Golf Course, with a up close view from the patio. You will find two bedrooms both with queen beds in this two bath home. You will have access to the entire home which includes the kitchen as well as full laundry. For your convenience the home owners do live next door and are available for any questions or concerns that arise.

Top guest favorite
A modern kitchen area features wooden cabinetry and stainless steel appliances, including a stove and refrigerator. Natural light fills the space through the window, and a cozy dining table is set nearby. Decorative elements, such as wall art, enhance the inviting design.
Home in Sonoita
4.99 out of 5 average rating, 348 reviews

Winemaker's Casita in the heart of Wine Country

The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.

Top guest favorite
A modern single-story house is positioned on a hillside, featuring a neutral-colored exterior and a flat roof. A clearly marked sign displays the address '340 North 2nd Ave'. Surrounding landscape exhibits natural desert vegetation and gravel.
Home in Patagonia
4.97 out of 5 average rating, 112 reviews

Patagonia Hilltop House with all the Amenities!

Forget your worries in this brand new spacious and serene space. It is fully stocked and has all the tools to cook a meal or sip wine next to the fire pit. The house is on a hill and the views are amazing. Enjoy relaxing just a few streets away from the heart of Patagonia in country comfort and style.

Guest favorite
Home in Nogales
4.95 out of 5 average rating, 194 reviews

Ibiza House, we invoice, near the consulate

Enjoy the simplicity of this accommodation in a very central, quiet and safe area, with a security booth, electric gate to protect your vehicle, the house is equipped to make you feel at home and we can invoice your trip, close to the American consulate, shopping centers and restaurants

Popular amenities for Patagonia house rentals

When is the best time to visit Patagonia?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceﺩ.ﺇ 599ﺩ.ﺇ 555ﺩ.ﺇ 595ﺩ.ﺇ 555ﺩ.ﺇ 551ﺩ.ﺇ 551ﺩ.ﺇ 551ﺩ.ﺇ 551ﺩ.ﺇ 551ﺩ.ﺇ 602ﺩ.ﺇ 551ﺩ.ﺇ 588
Avg. temp7°C8°C11°C14°C19°C24°C25°C23°C21°C16°C11°C7°C

Quick stats about house rentals in Patagonia

  • Total vacation rentals

    Explore 10 vacation rentals in Patagonia

  • Nightly prices starting at

    Patagonia vacation rentals start at ﺩ.ﺇ 184 per night before taxes and fees

  • Verified guest reviews

    Over 1,210 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Wi-Fi availability

    10 of Patagonia vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Patagonia rentals

  • 4.9 Average rating

    Patagonia stays are highly rated by guests—averaging 4.9 out of 5!

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