
Vacation rentals in O'Brien
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Top-rated vacation rentals in O'Brien
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Popular amenities for O'Brien vacation rentals
Other great vacation rentals in O'Brien
Guest favorite

Guest suite in O'Brien
4.88 out of 5 average rating, 56 reviewsLittle River Spring Cave divers poolside Hideaway

Home in O'Brien
4.72 out of 5 average rating, 76 reviewsCozy O’Brien Home w/ Fire Pit & Patio Near Rivers!
Superhost

Camper/RV in Branford
4.81 out of 5 average rating, 59 reviewsThunderbolt River Retreat
Top guest favorite

Cabin in Branford
5 out of 5 average rating, 9 reviewsBurnt Pine Ranch - Springs Retreat

Camper/RV in O'Brien
4.78 out of 5 average rating, 18 reviewsComfy Cougar on unique historic FL clay roads
Top guest favorite

Home in Bell
4.88 out of 5 average rating, 99 reviewsSuwannee River Getaway
Top guest favorite

Camper/RV in High Springs
5 out of 5 average rating, 11 reviewsEdith - Vintage Cruiser RV
Top guest favorite

Camper/RV in O'Brien
4.97 out of 5 average rating, 77 reviewsThe Birdhouse: Delightful RV w/ indoor fireplace
Destinations to explore
- Seminole Vacation rentals
- Central Florida Vacation rentals
- Orlando Vacation rentals
- Saint Johns River Vacation rentals
- Florida Panhandle Vacation rentals
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- Charleston Vacation rentals
- Ginnie Springs
- Ichetucknee Springs State Park
- Gilchrist Blue Springs State Park
- Manatee Springs State Park
- Madison Blue Spring State Park
- Keaton Beach
- Shired Island Trail Beach
- Ironwood Golf Course
- Depot Park
- Fanning Springs State Park
- Suwannee Country Club
- Florida Museum of Natural History
- Horseshoe Beach Park
- Suwannee River State Park