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Vacation rentals in New Madrid

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in New Madrid

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A charming lodge exterior is showcased with white siding and a dark brown porch. Two steps lead up to the covered entrance, framed by greenery. String lights add subtle illumination, enhancing the inviting appearance. The address is displayed prominently above the door.
Home in Hornbeak
4.85 out of 5 average rating, 113 reviews

Duck Nest Lodge

Located just across the lane from Reelfoot lake . Public ramp about 3/4 of mile away with several more close by. Enjoy lake views from the covered front porch. Living room with dish tv and internet. Full kitchen with cookware. Separate 20x20 garage for boat storage and a fish/duck cleaning house. Close to local restaurants and stores. 1 bedroom with queen bed , 2nd bedroom with bunk beds and a sofa sleeper. Can sleep 4 to 5 people. Pet friendly. Great location to enjoy beautiful Reelfoot Lake

Guest favorite
A single-story home is presented, featuring a white exterior with black shutters and a welcoming front door. A covered porch with hanging lights is visible, framed by two potted plants. The lawn is well-maintained, surrounded by trees under a clear blue sky.
Tiny home in Bloomfield
4.95 out of 5 average rating, 135 reviews

1-bedroom tiny home located in historic Bloomfield

Kick back and relax in this calm and stylish space located minutes from the Missouri Veterans Cemetery and The Stars and Stripes Muesum and Library. 1bdrm/1bath comfortably sleeps 2 and is furnished with everything you need. Inside you will find all new appliances, bedding, and linens. Circle drive with parking. No smoking or pets allowed. Local restaurants include Las Brasis and Elderland. Or try out locally owned businesses just 6.5 miles drive to Dexter such as Hickory Log and Dexter BBQ!

Guest favorite
The living room features a spacious sectional sofa in light tones, complemented by colorful drapes with floral patterns. A teal ottoman and a plush armchair add comfort, while a side table with a lamp provides soft lighting. A textured area rug anchors the design.
Home in Portageville
5 out of 5 average rating, 34 reviews

Cozy 2 Bedroom Cottage in Portageville - Sleeps 4

Looking for a cozy and comfortable Airbnb in Portageville? 🏡✨ This charming, newly updated cottage is the ideal destination for unforgettable memories with your loved ones. Conveniently located in a fantastic residential area right behind the town's elementary school, you're just moments away from local attractions, shopping, and dining spots. With ample parking, you can easily come and go as you please. Enjoy the comfort and convenience of our family-friendly home during your stay.

Top guest favorite
The exterior of a quaint guesthouse features a light green facade with a vibrant pink door. Two chairs are placed on the small porch, along with greenery surrounding the house, offering a welcoming entrance.
Guesthouse in Dexter
5 out of 5 average rating, 77 reviews

The Cottage at Evergreen

This guesthouse is located on the grounds of an historic, 1898, Dexter home. While a studio floor plan, it offers a queen bed, living room area, a small bathroom and a kitchenette. There is a smart TV, internet, a small fridge, microwave and Keurig coffee maker. The decor is a warm, cottage theme that is changed with the seasons. A small porch offers outdoor seating for 2. Beside the garage is a fire bowl and chairs guests may use. An assortment of snacks and drinks await you!

Top guest favorite
A cozy living room is presented, featuring a comfortable sofa with colorful cushions and a wooden coffee table at its center. A flat-screen TV is positioned against the wall, with a recliner and chair nearby. Light streams through the window, illuminating the warm tones of the space.
Home in Union City
4.95 out of 5 average rating, 361 reviews

Gloria’s on Exchange-Entire Home-3rd bedroom opt

Welcome to Gloria’s on Exchange, a cozy home away from home located in a quiet historic neighborhood. The bones of our home date to 1910, but this little house has received a loving renovation. Local art gives off a “rustic” feel, but all is completely tricked out with smart technology and very cozy furniture and bedding. 2 BEDROOMS/2 BATHS ARE INCLUDED IN THE LISTED PRICE. ADD ON OPTION for 3rd bedroom access w queen bed for $30 per night.

Superhost
The exterior of a 1930s house is presented, featuring a metal roof and a welcoming front porch with steps leading to the entrance. The porch is bordered by a white railing and is complemented by grassy areas surrounding the home.
Home in New Madrid
4.54 out of 5 average rating, 13 reviews

River Bend Guest House

Two bedroom home that sleeps 7-8 comfortably. Can sleep 10 if roll away beds are used. Fully furnished. Sheets, blankets, towels etc supplied. Soap, shampoo and conditioner supplied. Kitchen is stocked with dishes, pots, pans, silverware, etc. Smoking not allowed in the house but there is an enclosed porch where smoking is allowed. Baseboard heat. Window Air conditioners. Smoke and carbon monoxide detectors installed.

Top guest favorite
The charming house is framed by large trees, creating a natural border. A covered porch with seating is visible, inviting relaxation. Lush green grass and landscaping enhance the setting, while blue skies above contribute to a serene atmosphere. A wide, open space is present in the front yard.
Cottage in Martin
4.93 out of 5 average rating, 244 reviews

Country Cottage Home on 2 Acres Close to UTM

The whole group will enjoy easy access to everything from this centrally located place. Just down the road from the local medical businesses including the hospital and Cane Creek rehabilitation center , UTM and local shops. Quite and safe neighborhood with plenty of parking. One king bed in bedroom along with a couch and air mattresses. Extra linens included. Plenty of towels. Washer/dryer. Refrigerator,Stove,Microwave.

Top guest favorite
Home in New Madrid
5 out of 5 average rating, 7 reviews

Family Home near the MS River with a toy Room

The whole group will enjoy easy access to everything from this centrally located place. 3 blocks from the New Madrid boat ramp / levee. Less than 5 miles from HWY 55. Large family style home - on the first level - living room, dining room, kitchen, laundry room, guest bathroom, main bedroom and main bathroom. The upstairs has 2 bedrooms and a toy room with another full bathroom upstairs.

Top guest favorite
A cozy living room is showcased with a gray sofa adorned with decorative pillows, flanked by two red armchairs. A wooden coffee table sits in the center, holding a glass bowl and remote control. A rug adds texture, while natural light filters through a sheer curtain.
Home in Sikeston
5 out of 5 average rating, 26 reviews

Emma’s Cottage

Take it easy at this unique and tranquil getaway. Emma’s cottage is located in the historic north end of Sikeston, just minutes away from the local hospital and power plant, which makes it a perfect place for traveling professionals and people coming into town to visit friends and family. This cottage is 2 bedrooms, 1 bathroom, with a queen bed and a full bed.

Top guest favorite
A cozy bedroom features a dark brown accent wall, providing a warm backdrop for a spacious wooden bed dressed in crisp white linens. A small seating area with a round table and chairs is positioned nearby, with soft lighting from a stylish chandelier above.
Home in Clinton
4.99 out of 5 average rating, 192 reviews

The Peery House at Springhill Farms

The Peery House is our family home-place, built circa 1900, transformed into a quaint Airbnb. It is located on our farm, Springhill Family Farms in Western KY and is a great place for someone looking to get away from the busyness of life, looking for rest and relaxation or just looking for a unique, little farmhouse while passing through the area.

Top guest favorite
A cozy living room is arranged with four leather chairs and a small side table. A black fireplace serves as a focal point, accompanied by a mounted television above. Wall frames display various photographs, contributing to a homely atmosphere.
Home in Hornbeak
4.99 out of 5 average rating, 144 reviews

THE DREAMCATCHER

Beautiful brick home with lake view and access to Reelfoot Lake (no ramp), paved drive with ample parking for boat / trailer, back deck with table and chairs, open space kitchen and den, perfect for group fishing trip, hunting trip, or just sight seeing, (area known for its large population of eagles), quiet neighborhood, peaceful place to stay.

Guest favorite
A newly renovated modular home is set in a large yard with well-maintained grass. The home features a welcoming wrap-around deck with a colorful sign, surrounded by trees. The driveway provides ample parking space, enhancing the property’s accessibility.
Home in Hornbeak
4.92 out of 5 average rating, 51 reviews

Buddy's Reel 'Em Inn

Relax with the whole family at this peaceful place to stay. Buddy's Reel' Em Inn is located between HWY 22 and Lake Drive. 3 minute walk to the lake. Newly renovated modular home . This home has large yard space as well as truck and boat parking. House has all the amenities you would need except food!

Popular amenities for New Madrid vacation rentals

  1. Airbnb
  2. United States
  3. Missouri
  4. New Madrid County
  5. New Madrid